-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-observational-studies_methods.pdf
June 01, 2010 - paucity of RCT
evidence is common, particularly for many surgical and diagnostic procedures, and for
therapeutic … disease, facilitating interpretation of comparative benefits of a drug with respect to
duration of therapy … high-quality observational studies that focus on outcome measures such as persistency
or adherence to therapy … Challenges and opportunities for
pharmacoepidemiology in drug-therapy decision
making. … A review of uses of
health care utilization databases for
epidemiologic research on therapeutics.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/medicine-safety-call-center_research.pdf
September 01, 2007 - This
should include information on drug usage, interactions, adverse effects, and treatment outcomes … widely implemented mechanism for the reverse flow of information on adverse
events and medication and treatment … surveillance system has several
uses such as early detection of adverse drug reactions, discovery of new therapeutic … Further, the research team studied questionnaires designed
by researchers of the Center for Research Therapeutics … satisfaction, is a key driver in increased pharmacist involvement in patient
counseling and drug therapy
-
effectivehealthcare.ahrq.gov/sites/default/files/it-architecture-for-post-marketing-surveillance-arizona-cert.pdf
September 01, 2007 - This
should include information on drug usage, interactions, adverse effects, and treatment outcomes … widely implemented mechanism for the reverse flow of information on adverse
events and medication and treatment … surveillance system has several
uses such as early detection of adverse drug reactions, discovery of new therapeutic … Further, the research team studied questionnaires designed
by researchers of the Center for Research Therapeutics … satisfaction, is a key driver in increased pharmacist involvement in patient
counseling and drug therapy
-
effectivehealthcare.ahrq.gov/sites/default/files/01_arthritis_potential_high_impact_2012-12-10.pdf
January 01, 2012 - new (and new uses of existing) pharmaceuticals, medical devices,
diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and care
delivery innovations that address … MSC therapy
has the potential to be a first-line OA-treatment option that could regenerate articular … As with MSC therapy, preparation
ES-4
protocols and injection frequency vary among treatment … improvement provided by PRP for knee OA was 9 months.
27
Autologous PRP is not considered a drug or a therapeutic
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1506.pdf
June 01, 2015 - , screening and diagnostics, therapeutics, surgery, programs, and
care delivery innovations that address … Effective treatments are needed. … Patients with AS who did not respond to prior treatment with
TNF therapies showed significant improvement … Secukinumab (Cosentyx) for Treatment of Psoriatic Arthritis
Key Facts: Current treatments for PsA … Clinical Pathway at Point of This Intervention
AS treatment focuses on physical therapy and exercise
-
effectivehealthcare.ahrq.gov/sites/default/files/s77.pdf
October 01, 2007 - because legislation
requires Part D plans to have formularies that include drug
coverage across major therapeutic
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/lysosomal-storage-diseases-therapies_research-protocol.pdf
November 15, 2012 - Some 50 different LSDs have been identified.3
For a majority of LSDs, therapeutic management consists … have growth
impairment and pubertal delay.4 Supportive care may then consist of a combination of
therapies … What adjunct treatments are used with each FDA-approved ERT product?
3. … Concurrent/prior treatments
f. Length of follow up
g. … searches will be conducted in the United States Food and Drug Administration
website concerning the 6 ERT treatments
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/aggression_research-protocol.pdf
October 05, 2015 - is preventing proper treatment). … health outcomes, including improved
quality of life, functioning, or patient experience; improved therapeutic … Final health outcomes: improved quality of life, functioning, or patient
experience; improved therapeutic … therapeutic!relationshipP!
decreased!subsequent!aggressive!
behaviorP!decreased!subsequent!use! … Nonpharmacological Versus
Pharmacological Treatments for Adult Patients with Major Depressive Disorder
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_11-user-guide-to-ocer_130129.pdf
January 03, 2012 - of interest, mostly in
cases where there is differential adherence in the
data source between two therapeutic … Key Subpopulations
Therapies are often tested on an ideal population
(e.g., uncomplicated patients … However, there are several cases
where it is possible that the effectiveness of
specific therapies … would an unmeasured confounder
have to be to explain the magnitude of the
difference between two treatments … analysis and external
adjustment for unmeasured confounders in
epidemiologic database studies of therapeutics
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-report-3-acute-pain.pdf
June 01, 2022 - • Nonpharmacologic therapy versus inactive treatments or usual care. … outcome/
8. exp Therapeutics/
9. … (exercise [and related therapies],
cognitive behavioral therapy, meditation,
relaxation, music therapy … pharm therapy:
placebo; included therapies
vs. excluded therapies; dose
ranging studies; NSAID vs … controls; included
therapies vs. excluded
therapies
Outcomes Opioid therapy:
a-d, g, i.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prioritization-selection-of-harms.pdf
February 01, 2018 - similar across
interventions used to treat a given condition (e.g., medications, non-pharmacological therapies … Title
EPC, Year
Condition/ Population Harms Related Key Question(s) Interventions Harms Outcomes
Therapies … Dual agent therapy (statin
+ lipid modifying
medication) and
intensification of statin
therapy … Graded Exercise
Treatment;
pharmaceutical;
counseling/behavioral
therapy; complimentary
alternative … Therapeutic:
suppression of adrenal
glucocorticoid responsiveness;
increased appetite; weight gain
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-surveillance-report-3_0.pdf
May 01, 2022 - Opioid
treatments for chronic pain. … Nonopioid Pharmacologic Treatments for
Chronic Pain. … The therapeutic use of Δ9-
tetrahydrocannabinol (dronabinol) in
refractory neuropathic pain. … Efficacy of dronabinol as an adjuvant
treatment for chronic pain patients on opioid
therapy. … I-14
Journal of Cannabis Therapeutics.
2004;3(4):153-61. doi:
10.1300/J175v03n04_03.
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1412.pdf
December 01, 2014 - new (and new uses of existing) pharmaceuticals, medical
devices, diagnostic tests and procedures, therapeutic … , screening and diagnostics, therapeutics, surgery, programs, and
care delivery innovations that address … Because of even greater morbidity risk, therapeutic intervention is considered to
be urgently needed … In September 2014, FDA approved naltrexone-bupropion
(Contrave®, Orexigen Therapeutics, Inc., La Jolla … A
pathway to endoscopic bariatric therapies.
Gastrointest Endosc. 2011 Nov;74(5):943-53.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-nomination-apbi-breast-cancer.pdf
April 01, 2017 - When compared with whole breast
irradiation (WBI), APBI offers several benefits, including
reducing treatment … that subtle
variations in planning techniques and/or dose constraints
may substantially modify the therapeutic … Correa et al Practical Radiation Oncology: March-April 2017
treatment in every situation. … Radiotherapy and oncology
journal of the European Society for Therapeutic Radiology and
Oncology. 2007 … Impact of radiation treatment parameters and adjuvant systemic
therapy on cosmetic outcomes after accelerated
-
effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1506.pdf
October 01, 2015 - new (and new uses of existing) pharmaceuticals, medical
devices, diagnostic tests and procedures, therapeutic … Therapies targeting CFTR mutations have been proposed; however, therapies targeting
molecular defects … Additionally,
4.2% of patients who received combination therapy discontinued treatment because of adverse … However, this expert also
noted as more targeted therapies with high treatment costs emerge, payers … Prime Therapeutics LLC.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-radiation_appendixes.pdf
June 16, 2008 - Gesellschaft fur
Radiooncologie
http://www.degro.org/jsp_public/cms/index.jsp
European Society for Therapeutic … Radiology and Oncology
http://www.estroweb.org/estro/index.cfm
American Society for Therapeutic … Relative survival rates after alternative therapies
for uveal melanoma. … Clinical application of proton beams in the treatment
of uveal melanoma: the first therapies carried … Peripheral dose in ocular
treatments with CyberKnife and Gamma Knife radiosurgery compared
to proton
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-future_research.pdf
October 26, 2012 - power
Placebo comparators would contribute
indirect evidence to help guide
potential combination therapies … power
Placebo comparators would contribute
indirect evidence to help guide
potential combination therapies … Patients’ attitudes toward
novel therapies may inhibit enrollment; alternatively
they may be open to … understanding the gut microbiome is a long-term type of endeavor which has the potential to lead
to new therapeutics … , but in the interim, they are critical needs for immediate therapeutic options
and prevention).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/musculoskeletal-disorders-imaging_research-protocol.pdf
August 05, 2010 - conventional diagnostic imaging)
Interventions
• Positional MRI testing and positional MRI test-directed treatments … (i.e., effect on additional diagnostic testing, effect on limiting the differential
diagnosis)
o Therapeutic … impacts (i.e., effect on treatments received, changes in planned treatment
regimen)
• Clinical outcomes … selection of treatment. … Monitoring: assessing response to treatment or relapse after therapy.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-de-novo-processes_methods.pdf
September 01, 2009 - In surgical reviews, it may be important to know what supportive treatments
were used in the past compared … Checklists have been developed to improve the quality of reporting of meta-
analyses evaluating therapeutic … The
effect of antidepressant treatment on chronic
back pain. … Challenges in systematic reviews of
therapeutic devices and procedures. … Nonpharmacologic therapies for acute and
chronic low back pain: a review of the
evidence for an American
-
effectivehealthcare.ahrq.gov/sites/default/files/systematicreviewsreplacedenovo.pdf
September 01, 2009 - In surgical reviews, it may be important to know what supportive treatments
were used in the past compared … Checklists have been developed to improve the quality of reporting of meta-
analyses evaluating therapeutic … The
effect of antidepressant treatment on chronic
back pain. … Challenges in systematic reviews of
therapeutic devices and procedures. … Nonpharmacologic therapies for acute and
chronic low back pain: a review of the
evidence for an American