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61. Introduction to the Methods Guide for Medical Test Reviews | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/methods-guidance-tests-introduction/slides

62. Options for Summarizing Medical Test Performance in the Absence of a Gold Standard | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/methods-guidance-tests-performance/slides

63. Meta-analysis of Test Performance Evidence When There is a “Gold Standard” | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/methods-guidance-tests-metaanalysis/slides

64. PowerPoint Presentation (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-frameworks.ppt
    June 01, 2012 - Developing the topic and structuring systematic reviews of medical tests. … In revealing potential benefits and harms of the tests? … Adverse events of subsequent treatment/ other tests? … The same cases must be detected by both tests. … This requires that both tests detect the same cases.

65. PowerPoint Presentation (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-frameworks.ppt
    June 01, 2012 - Developing the topic and structuring systematic reviews of medical tests. … In revealing potential benefits and harms of the tests? … Adverse events of subsequent treatment/ other tests? … The same cases must be detected by both tests. … This requires that both tests detect the same cases.

66. Methods Guide for Medical Test Reviews Chapter 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-introduction_methods.pdf
    July 01, 2012 - Introduction With the growing number, complexity, and cost of medical tests, which tests can reliably … The second tenet is that medical tests (and therefore assessments of those tests) are about improving … tests are among the most commonly employed. … and prognostic tests, respectively. … ACCE Model Process for Evaluating Genetic Tests.

67. Decision Modeling (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-decision-modeling.ppt
    June 01, 2012 - Decision Modeling Deciding Whether To Complement a Systematic Review of Medical Tests With Decision … Deciding whether to complement a systematic review of medical tests with decision modeling. … Deciding whether to complement a systematic review of medical tests with decision modeling. … Inference between tests If the sensitivities of two tests are very similar, it is reasonable to expect … Extrapolation between tests Tests operate on same principle, so the clinical/biological characteristics

68. Decision Modeling (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-decision-modeling.ppt
    June 01, 2012 - Decision Modeling Deciding Whether To Complement a Systematic Review of Medical Tests With Decision … Deciding whether to complement a systematic review of medical tests with decision modeling. … Deciding whether to complement a systematic review of medical tests with decision modeling. … Inference between tests If the sensitivities of two tests are very similar, it is reasonable to expect … Extrapolation between tests Tests operate on same principle, so the clinical/biological characteristics

69. PROPOSALS FOR A PHASED EVALUATION OF (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-tests-proposals_research.pdf
    January 01, 2009 - Proposals for a phased evaluation of medical tests. Medical Tests—White Paper Series. … of diagnostic tests. … process for evaluating data on emerging genetic tests. … Can a similarly staged model be used for the evaluation of medical tests? … ACCE: A Model Process for Evaluating Data on Emerging Genetic Tests.

70. PROPOSALS FOR A PHASED EVALUATION OF (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/whitepaper3-lijmer02262010-2.pdf
    January 01, 2009 - Proposals for a phased evaluation of medical tests. Medical Tests—White Paper Series. … of diagnostic tests. … process for evaluating data on emerging genetic tests. … Can a similarly staged model be used for the evaluation of medical tests? … ACCE: A Model Process for Evaluating Data on Emerging Genetic Tests.

71. Appendix-Table-B-1-Observational-Studies (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendix-table-B-1-observational-studies.xlsx
    March 20, 2021 - PCR (viral genome sequencing of a subset) Positive: 1.9 tests per-person; 0.5 tests per-person after … first Ab+ test Negative:1.7 tests per-person; 0.9 tests per-person after first Ab+ test 0.5 Any (% … during second surge (%) Positive 0 tests: 3,525 (32) 1 test: 2,426 (22) 2–3 tests: 2,719 (25) 4+ tests … : 2,398 (22) Negative 0 tests: 124,165 (24) 1 test: 117,711 (23); 2–3 tests: 154,359 (30) 4+ tests: 118,036 … occurring in the positive cohort ≥90 days after primary PCR+ test PCR Tests per 10,000 days at risk

72. Methods Guide for Medical Test Reviews Chapter 12 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-prognostic_methods.pdf
    July 01, 2012 - tests do not necessarily address the most important questions about prognostic tests that are used … tests, are appropriate topics for systematic reviews. … These are commonly known as predictive tests. … In contrast to diagnostic tests, many prognostic tests are incorporated into multivariable regression … Many studies of prognostic tests do not provide this ultimate evidence.

73. Diagnosis and Treatment of Clinical Alzheimer’s-Type Dementia: Evidence Summary (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/Evidence%20Summary_1.pdf
    April 01, 2020 - tests (n=4,061), five of individual executive function tests (n=1,167), and ten of individual language … confirmed diagnoses, and none examined blood tests. … ; or any blood tests. … metrics, different cut-points for defining tests as abnormal, or combinations of tests, we could not … We found no analogous data for MRI or other CSF tests.

74. Appendicitis Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendicitis_executive.pdf
    December 01, 2015 - selected laboratory tests. … tests. … Among laboratory tests, white blood cell count, 15 C-reactive protein, and tests derived from combinations … that the results of earlier tests determine the choice of subsequent tests). … Comparative studies are needed for all tests and all populations.

75. Methods Guide for Medical Test Reviews Chapter 4 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-search_methods.pdf
    July 01, 2012 - Reviews Chapter 4 4-1 Chapter 4 Effective Search Strategies for Systematic Reviews of Medical Tests … When a review focuses on specific named tests, searching is relatively straightforward. … The FDA regulates many medical tests as devices. … ,26 all possible diagnostic tests were not known. … Effective Search Strategies for Systematic Reviews of Medical Tests.

76. Considering the Range of Decision-Relevant Effects (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-choosing-outcomes.ppt
    June 01, 2012 - genetic and prognostic tests. … tests Prognostic tests Genetic tests How To Choose Important Outcomes: Illustrative Examples Segal JB … Screening Tests Segal JB. … Diagnostic Tests Diagnostic tests from are differentiated from screening tests largely by the population … Prognostic Tests Prognostic tests are tests used in individuals with known disease to predict outcomes

77. Considering the Range of Decision-Relevant Effects (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-choosing-outcomes.ppt
    June 01, 2012 - genetic and prognostic tests. … tests Prognostic tests Genetic tests How To Choose Important Outcomes: Illustrative Examples Segal JB … Screening Tests Segal JB. … Diagnostic Tests Diagnostic tests from are differentiated from screening tests largely by the population … Prognostic Tests Prognostic tests are tests used in individuals with known disease to predict outcomes

78. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests_executive.pdf
    February 01, 2006 - test to confirm whether cancer is present, many women who do not have cancer will undergo diagnostic tests … Are there other factors that affect the accuracy or acceptability of the tests considered in Questions … To place the tests’ accuracy information into perspective, an average woman in the United States who … For women at this average level of risk of cancer after an abnormal mammogram, based upon the tests’ … Effectiveness of Noninvasive Diagnostic Tests for Breast Abnormalities.

79. A Primary Care-Focused, Computer-based Clinical Decision Support Tool to Assess Patients’ Risk for Deleterious BRCA Mutations | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/breast-cancer-genetic-tests/research

80. Methods Guide for Medical Test Reviews Chapter 3 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-outcomes_methods.pdf
    July 01, 2012 - tests, and prognostic tests, although prognostic tests are also discussed in Chapter 11. … It is likely that the direct health effects of screening tests are less than in tests used for diagnosis … and prognosis: screening tests are generally designed to be less invasive than tests used to make diagnoses … Example of a Diagnostic Test We differentiate diagnostic tests from screening tests largely by the population … effects than tests used for other purposes.