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501. Towards a Framework for Communicating Confidence in Methodological Recommendations for Systematic Reviews and Meta-Analyses (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methodological-recommendations-framework-communications_research.pdf
     September 01, 2013 - In addition, it is expected that most peers will agree that properly selected procedures or tests can … the likelihood of publication bias, and others who opted to focus on developing improved statistical tests … testable in a practical manner, e.g., through simulation studies comparing alternative statistical tests … The performance of tests of publication bias and other sample size effects in systematic reviews of … The appropriateness of asymmetry tests for publication bias in meta-analyses: a large survey.

502. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1512.pdf
     December 01, 2015 - AHRQ is interested in innovations in drugs and biologics, medical devices, screening and diagnostic tests … to identification of new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests … behavior after incidents such as disciplinary proceedings, hospital admission, or standardized screening tests … In these models, clinicians or other care providers first use various diagnostic tests to screen for

503. Gestational-Diabetes-Screening-Diagnosis Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gestational-diabetes-screening-diagnosis_executive.pdf
     October 01, 2012 - glucose (FPG), and risk factor-based screening, as well as other, less common tests such as HbA1c, … Therefore, no conclusions can be made about the test characteristics of the screening tests for this … However, because both the 75 g and 100 g load tests are positively linked with outcomes3,51 and the … Relationship between predictive values and prevalence for different screening tests Screening Test … Criteria for screening tests for gestational diabetes. Am J Obstet Gynecol. 1982;144(7):768-73.

504. Urinary-Incontinence-Treatment Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_surveillance.pdf
     October 29, 2012 - methods—questionnaires, checklists, scales, self reports of UI during a clinical examination, pad tests … methods questionnaires, checklists, scales, self reports of UI during a clinical examination, pad tests … different methods—questionnaires, checklists, scales, selfreports of UI during a clinical examination, pad tests … The majority of studies demonstrated that the tests had only small diagnostic value in distinguishing … The majority of studies demonstrated that the tests had only small diagnostic value in distinguishing

505. Disposition of Comments for Efficacy and Safety of Screening for Postpartum Depression (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_disposition-comments.pdf
     May 01, 2013 - overall are quite similar to those of our review in terms of performance characteristics of screening tests … and the importance of appropriate management of positive screening tests. … Especially when tests such as the EPDS have a reasonably high specificity. … We agree that studies of screening tests that do not exclude subjects with known preexisting disease … For scaled tests, we believe it is reasonable to vary the threshold for “normal” in order to estimate

506. Chronic Urinary Retention (CUR) Treatment | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/chronic-urinary-retention/research-protocol
     June 14, 2013 - Therefore, providers may first conduct tests to identify the etiology. … Commonly performed tests include: Urinalysis Urine culture Measures of renal function Prostate-specific … Retrograde cystourethrography While testing is commonly performed, there is no standard set of tests

507. Strategies for Improving the Lives of Women Aged 40 and Above Living with HIV/AIDS | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/women-hiv/research-protocol
     March 03, 2016 - The third interest area includes studies that assess the performance of tests for diagnosing co-occurring … Eligible are studies of the performance of tests, including imaging tests, laboratory measurements, and

508. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear_disposition-comments.pdf
     October 05, 2010 - Although clinical assessment is part of the diagnostic work-up, the literature indicates that clinical tests … The following statement has been revised to reflect this (page 14): “Since most clinical tests for rotator … Since clinical tests alone are often inaccurate in establishing the diagnosis of a tear, we believe

509. Disposition of Comments for Pulmonary Arterial Hypertension: Screening, Management, and Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_disposition-comments.pdf
     April 25, 2013 - Public Reviewer - ACCP 3 Abstract “Eighty studies involving 7224 patients evaluated biomarker tests … They are both tests that measure the same thing. … In group 1, these tests are used to look for a diagnosis to explain the patient’s symptoms. … Here the strength of the tests is based on their specificity or positive predictive value. … In group 2, the same tests are used to screen asymptomatic patients.

510. Cer-238-Cervical-Ripening-Appendix-E-1 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-e-1.xlsx
     January 01, 2009 - PGE2 gel (multiparous) administered by a midwife or doctor -After administration of study drug, if all tests … -Patient returned for weekly sonograms and twice weekly for non-stress tests cervical scoring and vaginal … Patient returned for weekly sonograms and twice weekly for non-stress tests NR Sawai, 1994 USA Fair

511. Frameworks for Determining Research Gaps During Systematic Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-research-steps-framework_research.pdf
     June 01, 2011 - , clinical assessments, and screening tests. … Research gaps relating to screening tests can be fit into the PICOS framework by considering these tests … Impact of gene expression profiling tests on breast cancer outcomes. … Special Considerations Research gaps relating to the accuracy of diagnostic tests can be fit into the … Research gaps relating to screening tests can be fit into the PICOS framework by considering these tests

512. Conducting Quantitative Synthesis when Comparing Medical Interventions: AHRQ and the Effective Health Care Program (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_conductingquantitativesynthesis.pdf
     October 01, 2010 - Statistical tests of heterogeneity are useful to identify variation among effects estimates, but their … As discussed earlier, tests of statistical heterogeneity should not be the only consideration for the … Statistical tests of heterogeneity are helpful, but investigators should not make a decision on combining … studies based only on tests of heterogeneity. 4. … interesting topics, such as meta-analysis of individual patient data, meta-analysis of diagnostic tests

513. Conducting Quantitative Synthesis when Comparing Medical Interventions: AHRQ and the Effective Health Care Program (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-quantitative-synthesis_methods.pdf
     October 01, 2010 - Statistical tests of heterogeneity are useful to identify variation among effects estimates, but their … As discussed earlier, tests of statistical heterogeneity should not be the only consideration for the … Statistical tests of heterogeneity are helpful, but investigators should not make a decision on combining … studies based only on tests of heterogeneity. 4. … interesting topics, such as meta-analysis of individual patient data, meta-analysis of diagnostic tests

514. Diagnosis and Management of Febrile Infants (0–3 Months) | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/febrile-infants-diagnosis-management/research
     March 27, 2012 - Current Page Topic Timeline Jan. 26, 2011 Topic Initiated Mar. 27, 2012 Systematic Review Diagnosis and Management of Febrile Infants (0–3 Months) Systematic Review Archived March 27, 2012 Web Version [NLM Site] Download Main Document PDF 2.2 MB Related Files Download Executive Summary [PDF · 277.9 K…

515. S77 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s77.pdf
     October 01, 2007 - Methods: We reviewed income and asset tests performed at the Salt Lake City VA in fiscal year 2005, and

516. Renal-Function Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-function_executive.pdf
     August 01, 2014 - Comparative Effectiveness Review Number 135 Cardiac Troponins Used as Diagnostic and Prognostic Tests … He is admitted to the hospital with pneumonia but repeated tests of troponin indicate a level of 0.24 … Should cardiac troponin testing include other diagnostic tests, such as stress testing or echocardiography … Cardiac Troponins Used as Diagnostic and Prognostic Tests in Patients With Kidney Disease.

517. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0095_04-10-2009.pdf
     January 01, 2009 - Effective Health Care Topic Number: 0142 Document Completion Date: 7-15-09 1 Results of Topic Selection Process & Next Steps  Noninvasive diagnosis of coronary artery disease in women will be developed as a systematic review by the Effective Health Care (EHC) Program.  When key questi…

518. Heart-Failure-Natriuretic-Peptide Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_executive.pdf
     November 01, 2013 - Covariates, especially age and renal function, have important effects on the performance of these tests … A gray zone assigned to inconclusive results of quantitative diagnostic tests: application to the use … Analytical and clinical performance of three natriuretic peptide tests in the emergency room. … ultrasound helps for differentiating the causes of acute dyspnea with available B-type natriuretic peptide tests

519. Grading Strength of Evidence: Interactive Quiz (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading-quiz.ppt
     September 02, 2013 - Any of these four domains can be used when they are relevant and the appropriate data or statistical tests

520. Grading Strength of Evidence: Interactive Quiz (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/grading-quiz.ppt
     September 02, 2013 - Any of these four domains can be used when they are relevant and the appropriate data or statistical tests