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361. Disposition of Comments Report for The Clinical Utility of Fractional Exhaled Nitric Oxide (FeNO) in Asthma Management (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-197-fractional-exhaled-nitric-oxide-disposition-comments.pdf
     December 20, 2017 - discuss the interpretability of the answer for each of these questions relative to the diagnostic tests … Abstract: FeNO test and reference tests were used to diagnose suspected asthma patients. … In a recent comparative meta-analysis of a variety of tests for diagnosing asthma (e.g. spirometry,

362. Attention Deficit Hyperactivity Disorder: Diagnosis and Treatment in Children and Adolescents - Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/deficit-hyperactivity-protocol.pdf
     November 01, 2021 - references address predominantly diagnostic questions such as the diagnostic validity of specific tests … Neuropsychological tests as well as genetic markers are included in 1a and 1b. … eligibility criteria are unchanged from the prior report, with the exception of now including further tests … being promoted, Vanderbilt Teacher Form Academic Performance Subscale, standardized achievement tests … If sufficient numbers of RCTs are available, we will review Begg and Egger tests.

363. Calcineurin_Inhibitors_Protocol_FINAL_10-07-2014 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/calcineurin-inhibitor_research-protocol.pdf
     October 08, 2014 - For KQ1a, KQ1b, and KQ2, the monitoring tests will include commercially available immunoassay tests … Internal validity and reporting adequacy: Were the tests performed with positive or negative control

364. Arcia-notes-Teresa (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/arcia-presentation.pdf
     May 29, 2025 -  be integrated   into with  the EHR so that the provider can   remind  patients of upcoming tests

365. Noninvasive Testing for Coronary Artery Disease | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/coronary-artery-disease-testing/research-protocol

366. Noninvasive Testing for Coronary Artery Disease | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/coronary-artery-disease-testing/research

367. Genetic Testing for Developmental and Intellectual Disabilities | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/genetic-testing-developmental-disabilities/research-protocol

368. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hypothyroidism-hyperthyroidism-screening-treatment_research-protocol.pdf
     March 11, 2010 - levels of 4.5-10 mIU/L based on insufficient evidence; they did recommend repeating thyroid function tests … Psychological or social impact of false positive screening tests. ii. … Thyroid Function Tests [mesh] 3.

369. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1412.pdf
     December 01, 2014 - AHRQ is interested in innovations in drugs and biologics, medical devices, screening and diagnostic tests … to identification of new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests … In the summary review, CDER scientists noted that in user-experience tests, adult and juvenile volunteers

370. women-hiv-protocol-160301 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/women-hiv_research-protocol.pdf
     March 01, 2016 - The third interest area includes studies that assess the performance of tests for diagnosing co-occurring … Eligible are studies of the performance of tests, including imaging tests, laboratory measurements,

371. Disposition of Comments for CER 153 Non-Muscle-Invasive Bladder Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/bladder-cancer-non-muscle-invasive_disposition-comments.pdf
     October 27, 2015 - This would be very helpful for the non cystoscopist who frequently orders these tests prior to referral … estimate is based on a single study, the confidence interval for the LR is similar to the other tests … as they seem to offer both clinical and commercial benefits beyond all other molecular diagnostic tests … These being; a) Replace the need for other urine-based tests in primary workup.

372. Comparative Effectiveness of Medications in Patients with Epilepsy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_disposition-comments.pdf
     March 01, 2012 - suggested change: A high level of statistical heterogeneity was detected (I2: 70.3 percent), but tests … Peer Reviewer #2 Results “No statistical heterogeneity was detected (I2: 0 percent), but tests for … We have made the suggested change: No statistical heterogeneity was detected (I2: 0 percent), but tests … Peer Reviewer #2 Results “No statistical heterogeneity was detected (I2: 0 percent), but tests for … Peer Reviewer #2 Results “No statistical heterogeneity was detected (I2: 0 percent), and tests for

373. GRADING THE STRENGTH OF A BODY OF EVIDENCE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
     November 01, 2013 - It does not address reviews of medical tests. … , they can evaluate consistency in magnitude of effect both qualitatively and through statistical tests … By contrast, as EPCs increasingly assess diagnostic tests, screening strategies, and health services … Grading a body of evidence on diagnostic tests. … On the one hand, when only a few studies constitute a body of evidence, then funnel plot tests may be

374. Making Healthcare Safer IV Rapid Response_Active Surveillance Culturing of Clostridioides difficile and Multidrug-Resistant Organisms: Methicillin-Resistant Staphylococcus aureus, Carbapenem-Resistant Enterobacterales, and Candida auris (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-active-infection-rapid-response.pdf
     May 01, 2024 - difficile disease.20,21 Laboratory methods used for ASC include both rapid, non-culture based molecular tests … using selective growth media to enhance MDRO recovery but with longer turn-around times than molecular tests

375. Disposition of Comments for CER 172 Clostridium Difficile Diagnosis Prevention Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/c-difficile-update_disposition-comments.pdf
     March 29, 2016 - line 10-11—on the flip side, clinicians are also not always aware of the low sensitivity of certain tests … TEP Reviewer #3 Introduction Questions may need to be considered for the clinical utility of the CDI tests … The summary statements for diagnostic tests have been reorganized. … Peer Reviewer #5 Discussion Page 34, line 40: the most clinically relevant tests are toxin assays. … If this is a key point, then many of the distinctions between the tests are less crucial (since 3 have

376. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0095_04-10-2009.pdf
     January 01, 2009 - Effective Health Care Topic Number: 0142 Document Completion Date: 7-15-09 1 Results of Topic Selection Process & Next Steps  Noninvasive diagnosis of coronary artery disease in women will be developed as a systematic review by the Effective Health Care (EHC) Program.  When key questi…

377. Disposition of Comments Report for Evaluation and Treatment of Cryptorchidism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_disposition-comments.pdf
     December 11, 2012 - Disposition of Comments Report for Evaluation and Treatment of Cryptorchidism Source: http://effectivehealthcare.ahrq.gov/search-for-guides-reviews-and- reports/?pageaction=displayproduct&productID=1353 Published Online: December 11, 2012 Comparative Effectiveness Research Review Disposition of Comments Repor…

378. Health Information Exchange (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/health-information-exchange_executive.pdf
     December 01, 2015 - that examined whether HIE improved resource use defined this as: (1) reduced ordering of laboratory tests … Studies of reduced laboratory tests, radiology exams, and costs showed the most consistent associated … Four U.S. studies found reductions in ED orders of lab tests and radiology exams,5-8 and three more … laboratory testing 4 and no impact on imaging,12 while a Finland-based study found that orders for lab tests

379. Disposition of Comments Report for Core Needle and Open Surgical Biopsy for Diagnosis of Breast Lesions: An Update to the 2009 Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_disposition-comments.pdf
     September 10, 2014 - We believe that comparisons among diagnostic tests are directly informative for clinical decisionmaking … (unlike assessments of individual tests in isolation). … Informal comparisons across tests suggest that – when used in the populations where they are considered … Long-term cancer outcomes represent clinical indirect effects of testing (via the impact of tests on … Please note that our statements about applicability refer to whether the populations, tests/interventions

380. Prostate-Cancer-Therapies-Update Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_research-protocol.pdf
     April 01, 2013 - They also estimated that there would be 100 to 120 men with false-positive tests and 110 men with true-positive … tests; among the latter, rates of complications from treatment would range from fewer than 1 death … clinical (based on a digital rectal examination of the prostate gland, prostate biopsy, and laboratory tests … We will use I-squared29 and tau30 tests to assess heterogeneity in study results. … Improved tests for a random effects meta-regression with a single covariate.