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341. Hypertension-Pulmonary-Arterial Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hypertension-pulmonary-arterial_research-protocol.pdf
     January 30, 2013 - be tailored specifically to the patient and can include a chest radiograph, full pulmonary function tests … polysomnography, left heart catheterization, a 6-minute walking test, and a multitude of laboratory tests … nuclear antigens, anti–SCL-70 antibody, pregnancy, and prothrombin time.12 Use of Noninvasive Tests … data (or related methodology paper of an included article) for any of the screening or diagnostic tests … type, derived from the core elements described in the Methods Guide.16 For studies of diagnostic tests

342. Towards a Framework for Communicating Confidence in Methodological Recommendations for Systematic Reviews and Meta-Analyses (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methodological-recommendations-framework-communications_research.pdf
     September 01, 2013 - In addition, it is expected that most peers will agree that properly selected procedures or tests can … the likelihood of publication bias, and others who opted to focus on developing improved statistical tests … testable in a practical manner, e.g., through simulation studies comparing alternative statistical tests … The performance of tests of publication bias and other sample size effects in systematic reviews of … The appropriateness of asymmetry tests for publication bias in meta-analyses: a large survey.

343. Screening and Diagnosing Gestational Diabetes Mellitus Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gestational-diabetes-screening-diagnosis_disposition-comments.pdf
     January 01, 2020 - The authors aimed to identify test properties for GDM screening and diagnostic tests, evaluate potential … job of organizing this body of evidence given the complex combinations of screening and diagnostic tests … Based on your findings, what test or tests will be most likely to optimize sensitivity and specificity … How do these screening tests relate to current practice in the US and Canada? … A review of diagnostic tests for type 2 diabetes was beyond the scope of the report.

344. Work Plan for Methods Research on (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/study-design-classification_research.pdf
     December 01, 2010 - Although the statistical tests accommodate for this to some extent, the more testers and response categories

345. Disposition of Comments for Efficacy and Safety of Screening for Postpartum Depression (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_disposition-comments.pdf
     May 01, 2013 - overall are quite similar to those of our review in terms of performance characteristics of screening tests … and the importance of appropriate management of positive screening tests. … Especially when tests such as the EPDS have a reasonably high specificity. … We agree that studies of screening tests that do not exclude subjects with known preexisting disease … For scaled tests, we believe it is reasonable to vary the threshold for “normal” in order to estimate

346. Disposition of Comments for Pulmonary Arterial Hypertension: Screening, Management, and Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_disposition-comments.pdf
     April 25, 2013 - Public Reviewer - ACCP 3 Abstract “Eighty studies involving 7224 patients evaluated biomarker tests … They are both tests that measure the same thing. … In group 1, these tests are used to look for a diagnosis to explain the patient’s symptoms. … Here the strength of the tests is based on their specificity or positive predictive value. … In group 2, the same tests are used to screen asymptomatic patients.

347. Quantitative Synthesis: Learning Objectives and Recommendations (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-learning-objectives-recommendations.pdf
     July 01, 2019 - On tests of the overall treatment effect in meta‐analysis with normally distributed responses. … Improved tests for a random effects meta‐regression with a single covariate.

348. Frameworks for Determining Research Gaps During Systematic Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-research-steps-framework_research.pdf
     June 01, 2011 - , clinical assessments, and screening tests. … Research gaps relating to screening tests can be fit into the PICOS framework by considering these tests … Impact of gene expression profiling tests on breast cancer outcomes. … Special Considerations Research gaps relating to the accuracy of diagnostic tests can be fit into the … Research gaps relating to screening tests can be fit into the PICOS framework by considering these tests

349. Gastric-Cancers-Supplementary-App-I (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-supplementary-app-i.xlsx
     January 01, 2019 - those in the FU plus LV arm (P interaction > .005 on the basis of a Bonferroni-adjusted P value for 10 tests … those in the FU plus LV arm (P interaction > .005 on the basis of a Bonferroni-adjusted P value for 10 tests

350. Can Physical Activity Improve the Health of Wheelchair Users? Amended Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/wheelchair-users-amended-protocol.pdf
     June 21, 2019 - priority outcomes are cardiovascular mortality; myocardial infarction; stroke; pulmonary function tests … of evidence include: cardiovascular mortality; myocardial infarction; stroke; pulmonary function tests … mortality, resting heart rate, resting blood pressure, lipid profile Respiratory • Pulmonary function tests … • Lipid profile • Resting blood pressure • Resting heart rate Respiratory Pulmonary function tests … myocardial infarction, stroke, development of diabetes, depression incidence, pulmonary function tests

351. Is there an easier way to test for Celiac disease? | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/is-there-an-easier-way-to-test-for-celiac-disease

352. Cer-238-Cervical-Ripening-Appendix-E-1 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-e-1.xlsx
     January 01, 2009 - PGE2 gel (multiparous) administered by a midwife or doctor -After administration of study drug, if all tests … -Patient returned for weekly sonograms and twice weekly for non-stress tests cervical scoring and vaginal … Patient returned for weekly sonograms and twice weekly for non-stress tests NR Sawai, 1994 USA Fair

353. Conducting Quantitative Synthesis when Comparing Medical Interventions: AHRQ and the Effective Health Care Program (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-quantitative-synthesis_methods.pdf
     October 01, 2010 - Statistical tests of heterogeneity are useful to identify variation among effects estimates, but their … As discussed earlier, tests of statistical heterogeneity should not be the only consideration for the … Statistical tests of heterogeneity are helpful, but investigators should not make a decision on combining … studies based only on tests of heterogeneity. 4. … interesting topics, such as meta-analysis of individual patient data, meta-analysis of diagnostic tests

354. Conducting Quantitative Synthesis when Comparing Medical Interventions: AHRQ and the Effective Health Care Program (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_conductingquantitativesynthesis.pdf
     October 01, 2010 - Statistical tests of heterogeneity are useful to identify variation among effects estimates, but their … As discussed earlier, tests of statistical heterogeneity should not be the only consideration for the … Statistical tests of heterogeneity are helpful, but investigators should not make a decision on combining … studies based only on tests of heterogeneity. 4. … interesting topics, such as meta-analysis of individual patient data, meta-analysis of diagnostic tests

355. Additional Patient Outcomes and Alternative Pathways in Evaluations of Testing | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/outcomes-testing-evaluation/research

356. Renal-Function Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-function_executive.pdf
     August 01, 2014 - Comparative Effectiveness Review Number 135 Cardiac Troponins Used as Diagnostic and Prognostic Tests … He is admitted to the hospital with pneumonia but repeated tests of troponin indicate a level of 0.24 … Should cardiac troponin testing include other diagnostic tests, such as stress testing or echocardiography … Cardiac Troponins Used as Diagnostic and Prognostic Tests in Patients With Kidney Disease.

357. S77 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s77.pdf
     October 01, 2007 - Methods: We reviewed income and asset tests performed at the Salt Lake City VA in fiscal year 2005, and

358. Executive Summary_Comparative Effectiveness Review No. 261_Postpartum Care up to 1 Year After Pregnancy: A Systematic Review and Meta-Analysis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-261-postpartum-care-executive-summary.pdf
     June 01, 2023 - Executive Summary_Comparative Effectiveness Review No. 261_Postpartum Care up to 1 Year After Pregnancy: A Systematic Review and Meta-Analysis Comparative Effectiveness Review Number 261 Postpartum Care up to 1 Year After Pregnancy: A Systematic Review and Meta-Analysis Executive Summary Main Points …

359. AHRQ Evidence-based Practice Center Program Research Gaps Summary: Primary Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
     March 01, 2022 - Key Messages • Many brief cognitive tests were highly (>0.8) sensitive and specific distinguishing … (FDG)- PET was highly sensitive and moderately (>0.5 to <0.8) specific; cerebrospinal fluid (CSF) tests … Interventions • Studies comparing the accuracy of individual and combined accuracy of cognitive tests … (including the MoCA, Mini-Cog, SLUMS, TICS, CANTAB, and other web-based tests), to help identify the … best test or combination of tests for maximizing classification accuracy and feasibility in typical

360. Heart-Failure-Natriuretic-Peptide Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_executive.pdf
     November 01, 2013 - Covariates, especially age and renal function, have important effects on the performance of these tests … A gray zone assigned to inconclusive results of quantitative diagnostic tests: application to the use … Analytical and clinical performance of three natriuretic peptide tests in the emergency room. … ultrasound helps for differentiating the causes of acute dyspnea with available B-type natriuretic peptide tests