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321. Localized Prostate Cancer | Effective Health Care
     effectivehealthcare.ahrq.gov/decision-aids/prostate-cancer/07.html
     June 08, 2018 - Risk groups may help your doctor decide whether you need to have more tests before making a treatment

322. Research on Optimal Second-Line Therapy for Hypertension | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/hypertension-therapy/abstract
     January 01, 2005 - antihypertensive drug use; to compare the changes in intermediate measures (e.g., blood pressure, laboratory tests

323. Disposition of Comments for Comparative Effectiveness Review 130 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/preoperative-testing_disposition-comments.pdf
     January 29, 2014 - with concerns about the sizable cost of testing, overtesting and the consequences of false positive tests … (e.g., complications due to unnecessary biopsies performed to follow up false positive laboratory tests … Thank you Peer Reviewer #8 Introduction The subsection on “preoperative tests” seems to be repetitive … e.g., pain, hemorrhage, or bruising from a blood draw, exposure to ionizing radiation from imaging tests … Given the heterogeneity of tests and surgeries, almost all our evidence boils down to single studies

324. Kravitz_ECCS2012 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/kravitz_eccs2012.pdf
     January 01, 2012 - outpatients made requests for physician action. o Requests were made for:  Laboratory testing, imaging tests … for care after their visits. o Most, but not all, of the unmet expectations concerned medications, tests

325. Renal-Cancer Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_research-protocol.pdf
     April 20, 2015 - or biopsy) Composite models (combination of demographics, clinical characteristics, blood/urine tests … biopsy) • Composite models (combination of demographics, clinical characteristics, blood/urine tests … .[38-39] The results of the diagnostic tests will be tabulated and sensitivity, specificity, positive … of bias • Medium risk of bias • High risk of bias Well designed and executed studies of new tests … Grading a Body of Evidence on Diagnostic Tests. In: Chang SM, Matchar DB, Smetana GW, et al, eds.

326. Interventions To Improve Antibiotic Prescribing for Uncomplicated Acute Respiratory Tract Infections | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/antibiotics-respiratory-infection/clinician
     April 06, 2016 - Interventions include clinical strategies (e.g., use of point-of-care diagnostic tests, delayed antibiotic … Other point-of-care tests (such as the rapid strep test, multi-viral polymerase chain reaction [PCR] … testing) reduced antibiotic prescribing, but evidence on adverse consequences associated with these tests … otitis media; CRP = C-reactive protein; PCR = polymerase chain reaction Clinical Point-of-care tests

327. Instrumental Variable Methods in Comparative Safety and Effectiveness Research | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/instrumental-variable-methods/research
     May 14, 2010 - Specification tests in econometrics. Econometrica 1978;46:1251-1271. 69. Wu DM. … Alternative tests of the independance between stochastic regessors and disturbances. … These tests assume that one has available a valid IV and the test then attempts to determine whether … Tests of this sort have been proposed by Durbin, 39 Hausman, 40 and Wu. 41 One limitation of these … tests is that they assume homogeneous treatment effects.

328. An analytical framework for quantifying components of variability in prescriber decisions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/instrumental-variable-methods_research.pdf
     April 01, 2010 - Specification tests in econometrics. Econometrica 1978;46:1251- 1271. 69. Wu DM. … Alternative tests of the independance between stochastic regessors and disturbances. … These tests assume that one has available a valid IV and the test then attempts to determine whether … Tests of this sort have been proposed by Durbin, 67 Hausman, 68 and Wu. 69 One limitation of … these tests is that they assume homogeneous treatment effects.

329. Decision-Analytic Modeling to Evaluate Benefits and Harms of Medical Tests – Uses and Limitations | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/benefits-harms-modeling/research

330. SEAD Submission Form for Blood-based Tests for Multiple Cancer Screening: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/form/cell-free-dna/sead

331. Template for Reports Developed (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-future_research.pdf
     October 26, 2012 - Comparative data were not found for many currently used tests. … Substantial differences in false positives, that is, specificity, were not found among the tests that … Comparative data were not always available for the three currently available gene detection tests. … Comparative data were not found for many currently used tests. … Comparative data were not found for many currently used tests.

332. Liver-Cancer Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
     October 01, 2014 - liver that are clinically suspicious for HCC.4 The evaluation phase involves the use of additional tests … We excluded studies in which the reference standard involved one of the imaging tests under evaluation … Technical information for different imaging tests was abstracted.11 Assessment of Methodological Risk … We identified 274 studies that evaluated diagnostic accuracy of imaging tests. … Fifty-four studies evaluated diagnostic accuracy of imaging tests in diagnosing HCC among individuals

333. Topic Suggestion Description | Effective Health Care Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/topic-nomination-lower-urinary-tract-symptoms-secondary-to-benign-prostatic-hyperplasia-1questions-to-consider-1-what-is-the-comparative-efficacy-and-effectiveness-of-currently-available-and-emerging-treatments-for-lower-urin
     October 31, 2013 - What are the necessary tests to determine if BPH or bladder outlet obstruction (BOO) is the cause of … What are the necessary tests to determine if a patient with a predominant complaint of nocturia has a … Should these tests be required or recommended to determine if BPH is the cause of LUTS before treatment

334. Pharmacologic and Non-pharmacologic Therapies in Adult Patients with Acute Exacerbation of COPD: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/copd/protocol
     October 10, 2018 - Mortality; Quality of life; Hospital admission; ICU admission; Physical capacity (timed walking tests … , endurance tests) Number of intubations KQ 1, 2,3 & 4: Adverse effects of interventions (harms … Mortality; Quality of life; Hospital admission; ICU admission; Physical capacity (timed walking tests … , endurance tests) Number of intubations None Timing All None Settings Outpatient, hospital … will evaluate potential publication bias by evaluating funnel plots symmetry and using statistical tests

335. Prostate-Cancer-Risk-Assessment-Genes Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-risk-assessment-genes_executive.pdf
     July 01, 2012 - Amidst substantial debate,17-23 the argument has been made for developing more accurate screening tests … In general, proposed tests with an AUC of 75 percent or less are unlikely to be clinically useful.60,61 … For one of the panels,54 we noted the development of separate tests for SNPs in steroid hormone pathway … the risk models based on SNP panels improved the AUC only marginally compared with non–SNP-based tests … Misconceptions about the use of genetic tests in populations. Lancet. 2001;357(9257):709-12.

336. Disposition of Comments for PCA3 Testing for the Diagnosis and Management of Prostate Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-test_disposition-comments.pdf
     April 01, 2013 - that have analyzed 2 or more tests in the same patients. … TEP # 13 ES-10, line 23 Refers to the PCA3 tests as "noninvasive" and "from urine." … Would it be sufficient to simply say that the tests are done using a urine sample, or to qualify the … At very low, or high specificities, the two tests will be most likely similar. … screening tests for cancer or for other diseases.

337. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - AHRQ is interested in innovations in drugs and biologics, medical devices, screening and diagnostic tests … to identification of new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests … .21 These tests may include blood tests to measure nutrient levels in the bloodstream, abdominal x-rays … or ultrasound to provide images of the abdomen, stool-sample tests to detect infection or unabsorbed … and protein, endoscopy or 4 colonoscopy to examine the inside of the intestine, and other tests

338. Enzyme-Replacement Therapies for Lysosomal Storage Diseases | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/lysosomal-storage-diseases-therapies/technical-brief
     January 02, 2013 - and skeletal abnormalities, renal function, cardiac function, pulmonary function, growth, and walking tests

339. Real World Effectiveness of Carotid Artery Stenting (CAS) in Medicare Patients | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/coronary-stents-effectiveness/abstract
     April 14, 2010 - from 2005-2008; 3) all Medicare patients who had CAS or CEA; and 4) patients who had carotid imaging tests

340. Topic 0502 Non-Muscle Invasive Bladder Cancer NSD FINAL_SJ (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0587-131115.pdf
     March 06, 2013 - How do the accuracies of imaging tests, cystoscopy, urine cytology, urine-based from Nominator: biomarkers