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301. Disposition of Comments Report for Imaging Techniques for the Diagnosis and Staging of Hepatocellular Carcinoma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_disposition-comments.pdf
     October 23, 2014 - We agree that heterogeneity was substantial; however, this is expected in reviews of diagnostic tests … We added Table 24 with post-test probability for various imaging tests in populations with different … This represents an enormous undertaking - a huge number of studies of different tests and conducted … In fact, in clinical practice, a patient may have multiple diagnostic tests, with additional value … In addition, some diagnostics tests are synergistic.

302. Cardiac Troponins Used as Diagnostic and Prognostic Tests in Patients With Kidney Disease | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/renal-function/research
     August 11, 2014 - Nov. 24, 2014 Disposition of Comments Report Cardiac Troponins Used as Diagnostic and Prognostic Tests

303. Disposition of Comments Report for Cardiac Troponins Used as Diagnostic and Prognostic Tests in Patients Wtih Kidney Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-function_disposition-comments.pdf
     August 11, 2014 - Disposition of Comments Report for Cardiac Troponins Used as Diagnostic and Prognostic Tests in Patients … Disposition of Comments Report Research Review Title: Cardiac Troponins Used as Diagnostic and Prognostic Tests … Cardiac Troponins Used as Diagnostic and Prognostic Tests in Patients With Kidney Disease. … Summary Change title to: “Critical Review of Cardiac Troponins Used as Diagnostic and Prognostic Tests … with Kidney Disease” We changed the title to “Cardiac Troponins Used as Diagnostic and Prognostic Tests

304. Siminoff_ECCS2012 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/siminoff_eccs2012.pdf
     January 01, 2012 - a specific set of facts, namely the patient's reported signs and symptoms and accrued objective  tests …    Medical  history  Physical exam  Laboratory  tests • Patient’s  approach o Application … Percentage Confidant confirmed symptom  appraisal 56.0% Confidants advocated getting more information/tests

305. Imaging Techniques for Treatment Evaluation for Metastatic Breast Cancer | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/breast-cancer-imaging/research-protocol
     December 17, 2013 - $115 for ultrasound to $1114 for PET-CT, 9,10 increasing the need to determine whether more expensive tests … and bone, in addition to obtaining medical histories, physical examinations, and relevant laboratory tests … For example, are patients aware that the accuracy of these imaging tests varies? … Do any themes, such as cost, accuracy of tests, or discomfort, inconvenience, often arise when metastatic … Do patients generally know how much they will have to pay out of pocket for imaging tests?

306. breast-cancer-imaging-protocol-131217 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-cancer-imaging_research-protocol.pdf
     December 17, 2013 - $115 for ultrasound to $1114 for PET-CT,9, 10 increasing the need to determine whether more expensive tests … and bone, in addition to obtaining medical histories, physical examinations, and relevant laboratory tests … For example, are patients aware that the accuracy of these imaging tests varies? 3. … Do any themes, such as cost, accuracy of tests, or discomfort, inconvenience, often arise when metastatic … Do patients generally know how much they will have to pay out of pocket for imaging tests?

307. Arthritis-Knee-Physical-Therapy Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-knee-physical-therapy_research-protocol.pdf
     April 01, 2010 - • Population Same as KQ1 • Interventions Tests and measurements (intermediate outcomes of … physical therapy): o Muscle performance or strength tests: – Manual muscle test – Hand-held … For KQ 2, we will include the studies of tests and measures in adults with knee OA. … Studies that validated tests and measures in populations with other diseases. 6. … Studies that reported absolute values of the diagnostic tests in adults with knee OA. 7.

308. Chronic-Kidney-Disease-Anemia-2011 Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-kidney-disease-anemia-2011_executive.pdf
     January 01, 2011 - What are the adverse effects or harms associated with the treatments guided by tests of iron status? … Not rated (descriptive data) • There is a lack of generally accepted reference standard tests for … Low • Two short-term RCTs (4 and 6 months) showed a reduction in the number of iron status tests and … Typically, the assessment of diagnostic tests follows the Fryback approach,47 progressing from the … , blinded interpretation of test results, and independence of the index and reference standard tests

309. AHRQ’s Evidence-based Practice Center Program: Synthesizing evidence to improve health care practice and delivery (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/epc-health-care-practice-delivery.pdf
     November 01, 2022 - ◆ Clinical areas (e.g., treatments for depression, management of opioid overdose) ◆ Diagnostic tests

310. Localized Prostate Cancer | Effective Health Care
     effectivehealthcare.ahrq.gov/decision-aids/prostate-cancer/22.html
     June 08, 2018 - How willing would you be to have frequent testing to monitor your cancer (for example, blood tests and

311. The series of articles beginning with this issue of the Journal form the most up-to-date version of the Guide for Conducting Comparative Effectiveness Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-principles_methods.pdf
     August 01, 2009 - • Present benefits and harms for different treatments and tests in a consistent way so that decisionmakers … Balance of Benefits and Harms CERs aim to present benefits and harms for different treatments and tests … also identified future research that is needed, including methodologies for the assessment of medical tests … address issues such as when and how to use modeling, how to assess the quality of studies of medical tests … outcomes on decisions to use a medical test, and the assessment of studies of genetic and prognostic tests

312. Project Name: (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_disposition-comments.pdf
     October 25, 2011 - We have added a future research recommendation for studies that evaluate the appropriate tests based … A more accurate statement is "If screening tests are found to be sufficiently predictive..." … Tests" We have changed all the “Wakefulness tests” titles to “Objective sleepiness and wakefulness … tests” 4 Page 52 line 7 "The range of differences between the two interventions was large (-1.0 … results of initial tests) with full testing (overnight PSG) alone.

313. Antibiotics-Respiratory-Infection Clinician (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_clinician.pdf
     March 01, 2016 - Interventions include clinical strategies (e.g., use of point-of-care diagnostic tests, delayed antibiotic … Other point-of-care tests (such as the rapid strep test, multi-viral polymerase chain reaction [PCR … testing) reduced antibiotic prescribing, but evidence on adverse consequences associated with these tests … Interventions To Reduce Antibiotic Prescribing Category Explanations and Examples Clinical Point-of-care tests

314. Disposition of Comments Report for Noninvasive Technologies for the Diagnosis of Coronary Artery Disease in Women (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_disposition-comments.pdf
     June 12, 2012 - Peer Reviewer 2 General Added value is important for screening tests and risk factors, but may not be … Does this mean that these tests should not be performed in the clinical environment? … Noninvasive tests may be equally predictive or even better predictive of events during follow-up. … Noninvasive tests may be equally predictive or even better predictive of events during follow-up. … The comparative cost of these tests is outside the scope of our report.

315. Breast-Biopsy-Update Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
     September 01, 2014 - We did not use a search filter for studies of diagnostic tests to increase search sensitivity.10, 11 … Reference standard tests also differed across studies: 26 used open biopsy on all included patients; … In general, differences among tests were relatively small: for example, differences in sensitivity … This allowed us to assess the comparative performance of tests (when using the same type of imaging … Grading a body of evidence on diagnostic tests. In: Chang SMM, D. B. Smetana, G. W. Umscheid, C.

316. Interventions for Preventing Cognitive Decline, Mild Cognitive Impairment, and Alzheimer’s Disease | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/cognitive-decline/research-protocol
     March 23, 2016 - Biomarkers are measured using lab tests and imaging (e.g., total brain and hippocampal volumes; white … how to distinguish between normal age-related cognitive decline, diagnosed exclusively by cognitive tests … cognitive manifestations of MCI and dementia, diagnosed using specific biomarkers and neurocognitive tests … Furthermore, the cognitive disorder must be based on objective cognitive tests. … For KQ3: Adults with normal or abnormal cognition who have had testing such as cognitive tests, blood

317. Microsoft Word - cognitive-decline-protocol-160322.docx (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cognitive-decline_research-protocol.pdf
     March 22, 2016 - Biomarkers are measured using lab tests and imaging (e.g., total brain and hippocampal volumes; white … how to distinguish between normal age-related cognitive decline, diagnosed exclusively by cognitive tests … Furthermore, the cognitive disorder must be based on objective cognitive tests. …  test results Brain  matter volume Brain  cell  activity level As determined  by: �Blood/CSF  tests … For  KQ3:  Adults with  normal or abnormal cognition  who  have  had testing such   as  cognitive  tests

318. Effective Health Care Program
     effectivehealthcare.ahrq.gov/health-topics/medicare-0
     December 08, 2017 - Methods Guide for Authors of Systematic Reviews of Medical Tests: A Collaboration Between the Agency

319. Quantitative Synthesis: Chapter 4. Quantifying, Testing, and Exploring Statistical Heterogeneity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-4.pdf
     July 01, 2019 - plots can be difficult to detect visually, and may owe to multiple contributing factors.8 ► Formal tests … least one study has an effect different from the summary effect. • A common statistical heterogeneity tests … Improved tests for a random effects meta‐regression with a single covariate. … Improved tests for a random effects meta‐regression with a single covariate.

320. Updating Current Effectiveness Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-assessment-research-updates_research.pdf
     September 15, 2008 - 6 3 Background The Effective Health Care Program (EHC) researches available health care tests … health care they want to have, and can help clinicians and health care purchasers to focus on the best tests … Effectiveness of Noninvasive Diagnostic Tests for Breast Abnormalities 02/2006 3. … We conducted pilot tests of the initial letter among the principal investigator and several Technical … for Gastroesophageal Reflux Disease 6 1 1 4 Yes Yes Effectiveness of Noninvasive Diagnostic Tests