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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0334_08-04-2010.pdf
    January 01, 2010 - An evidence-based review is needed, however, to determine whether and how these tests should be used
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-disease-medicine_research-protocol.pdf
    November 01, 2010 - damage, including abnormalities in the composition of the blood or urine, or abnormalities in imaging tests … behaviors, and/or co-morbid or biological risk factors; (2) Whether the accuracy of available screening tests … deficiency, hyperkalemia) Possible Harms - Misclassification/false positive diagnosis - Unnecessary tests … deficiency, hyperkalemia) Possible Harms - Misclassification of CKD severity - Unnecessary tests … The quality of studies of diagnostic tests included in the review will be assessed using the QUADAS
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-201-indoor-allergen-asthma-disposition-comments.pdf
    February 15, 2018 - Moreover, 43 studies confirmed sensitization using skin prick tests, while 13 used blood tests. … The authors should be aware that blood tests are less reliable than skin tests (epicutaneous testing … versus blood tests. … Ten of the 16 used skin prick tests, while the other studies used blood tests. … Ten of these 16 used skin prick tests, while the other studies used blood tests.
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-cancer-imaging_technical-brief.pdf
    October 01, 2014 - other hand, if tests show treatment is working, that is very heartening for patients. … • Patient preferences usually push clinicians to do more tests and more expensive tests. … • Patients often don’t have tests explained to them, particularly the pros/cons, etc. … • Patients don’t grasp the use of tests, their accuracy, interpretation, etc. … • Patients expect their tests to show them if treatment has been successful.
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/pressure-ulcer-prevention_research-protocol.pdf
    January 10, 2012 - Risk assessment Risk Assessment/ or Risk Factors/ or Nursing Assessment/ or "Predictive Value of Tests … Risk Assessment/ 7 Risk Factors/ 8 Nursing Assessment/ 9 "Predictive Value of Tests … Published Online: January 10, 2012 16 8 Nursing Assessment/ 9 "Predictive Value of Tests … Risk Factors") OR "risk factors" S9 (MH "Nursing Assessment") S10 (MH "Predictive Value of Tests … Risk Assessment/ 7 Risk Factors/ 8 Nursing Assessment/ 9 "Predictive Value of Tests
  6. effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-is-the-comparative-effectiveness-of-genetic-and-other-diagnostic-tests-to-identify-and-treat-intellectual-and-developmental-disabilities-caused-by-genetic-mutations-in-post-natal-to-early-childhood-populations
  7. effectivehealthcare.ahrq.gov/sites/default/files/c-diff-infections-nomination-140925.pdf
    February 19, 2014 - § Immunoassays for toxins A and B § Gene detection tests versus immunoassays for toxins A and B §
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-knee-physical-therapy_executive.pdf
    November 01, 2012 - treatments (any known) Intermediate Outcomes Joint movement, swelling, impairments in performance tests … For Key Question 2, we did not review validation of tests in populations with diseases other than knee … We reviewed validity and reliability of the tests within the scope of physical therapy practice. … Diagnostic tests 4: likelihood ratios. BMJ. 2004 Jul 17;329(7458):168-9. PMID: 15258077. 49. … Diagnostic tests 3: receiver operating characteristic plots. BMJ. 1994 Jul 16;309(6948):188.
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/epc-evidence-reviews-federal-agencies.pdf
    July 01, 2020 - Methods Guide for Medical Test Reviews https://effectivehealthcare.ahrq.gov/topics/methods-guidance-tests
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prioritization-selection-of-harms.pdf
    February 01, 2018 - lower priority than clinical outcomes, for certain interventions (e.g., those addressing diagnostic tests … Year Condition/ Population Harms Related Key Question(s) Interventions Harms Outcomes Imaging Tests … MRI- allergic reactions to intravenous contrast agents and nephrogenic systemic fibrosis Imaging Tests … and intensification of statin therapy Cardiac Troponins Used as Diagnostic and Prognostic Tests … ); women of reproductive age, pregnant women, and the elderly What are the harms of diagnostic tests
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-imaging_disposition-comments.pdf
    October 01, 2014 - Peer Reviewer #5 General Comments Good description of current studies on multiple tests. … Personalized medicine and blood tests - unclear whether advocacy for research for these is related to … While we agree that personalized medicine and blood tests are not relevant imaging modalities, they … In fact, in clinical practice, a patient may have multiple diagnostic tests, with additional value from … In addition, some diagnostics tests are synergistic and are ordered to better evaluate findings from
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/urinary-incontinence-update_research-protocol.pdf
    June 06, 2017 - Conversely, researchers define improvement as a decrease in the amount of UI based on objective tests … be patient-centered and based on factors important to women, rather than on the results of invasive tests … be evaluated according to what women report to be significant symptom changes based on objective tests … Bladder and pelvic tests that do not measure UI specifically or are used for diagnostic purposes (e.g … Interventions (KQ 1-4) Adverse events of intervention (KQ 1b/d, 2b/d, 3b, 4b) UI Measures: Pad tests
  13. effectivehealthcare.ahrq.gov/sites/default/files/estimation-and-reporting_chapter-3.pptx
    January 01, 2013 - Cautions for tests of interactions: Generally have low power to detect subgroup effects Do not correspond … still a danger of falsely detecting a difference in subgroup effects if we perform separate interaction tests … adequate statistical power to detect subgroup effects and to appropriately report results of interaction tests
  14. effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1506.pdf
    December 01, 2015 - AHRQ is interested in innovations in drugs and biologics, medical devices, screening and diagnostic tests … to identification of new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests
  15. effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - AHRQ is interested in innovations in drugs and biologics, medical devices, screening and diagnostic tests … to identification of new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests
  16. effectivehealthcare.ahrq.gov/sites/default/files/developmental-delays-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - AHRQ is interested in innovations in drugs and biologics, medical devices, screening and diagnostic tests … to identification of new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests
  17. effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - AHRQ is interested in innovations in drugs and biologics, medical devices, screening and diagnostic tests … to identification of new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests
  18. Brooks_ECCS2012 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/brooks_eccs2012.pdf
    January 01, 2012 - . • There are  tests  to  find it early. • We don’t  yet  know  if the benefits of testing
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prosthesis_research-protocol.pdf
    March 16, 2017 - OMTs are used as predictive tools (predictive tests). … Predictive tests should be valued with respect to their ability to predict future outcomes. … KQ • Also allow studies of amputees, whether or not they use LLPs (KQ 1 & 2) Predictors/Tools/Tests … (KQ 1 & 2) • Assessment techniques (that are used prior to prescription) (KQ 1) o Tests, scales, … Predictor tools (used prior to prescription to predict functional outcomes with prosthesis) (KQ 2) o Tests
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-decision-support-tools_research-protocol.pdf
    November 12, 2013 - For all statistical tests, except those for heterogeneity, statistical significance will be defined … qualitative dispositions based on the results of the SIP requests, rather than perform formal statistical tests … Although these tests are often referred to as tests for publication bias; reasons other than publication … between smaller and larger studies, other biases, and chance, rendering the interpretation of the tests … non-specific and the tests noninformative.39, 40 Therefore, instead of relying on statistical tests

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