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221. Effectiveness of Early Diagnosis, Prevention, and Treatment of Clostridium difficile Infection (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_disposition-comments.pdf
     March 01, 2012 - the gene-detection tests are generally more sensitive. … However, the use of toxin gene- detection tests has increased in recent years. … between tests. … results from expert in- house use of non-commercial tests. … We didn’t want to exclude studies that used other reasonable reference tests.

222. Localized Prostate Cancer | Effective Health Care
     effectivehealthcare.ahrq.gov/decision-aids/prostate-cancer/11.html
     June 08, 2018 - You will have regular checkups that might include lab tests, ultrasounds, and biopsies. … Watchful waiting means you have regular checkups with your doctor, but you may not have tests done often

223. Multigene Panels in Prostate Cancer Risk Assessment | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/prostate-cancer-risk-assessment-genes/research
     July 03, 2012 - validity, and clinical utility of commercially available single nucleotide polymorphism (SNP) panel tests … insufficient to conclude that the panels assessed would perform adequately as screening or risk stratification tests

224. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0398_06-17-2008.pdf
     January 01, 2008 - What impact would standardization of these marker tests have on the effectiveness of iron replacement …  The two traditional tests used to assess serum iron status are TSAT and serum ferritin. … Although both tests are easy to perform, there are some limitations to using these traditional laboratory

225. What are the comparative diagnostic accuracy, diagnostic thinking, therapeutic, and patient outcome efficacy of non-invasive tests for the risk stratification of patients with coronary artery disease? | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-are-the-comparative-diagnostic-accuracy-diagnostic-thinking-therapeutic-and-patient-outcome-efficacy-of-non-invasive-tests-for-the-risk-stratification-of-patients-with-coronary-artery-disease
     February 27, 2012 - diagnostic accuracy, diagnostic thinking, therapeutic, and patient outcome efficacy of non-invasive tests … Multiple stress tests are available to aid in the evaluation of patients at intermediate risk of patients

226. Comparative Effectiveness of Screening for Glaucoma | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/glaucoma-screening/research-protocol
     November 16, 2010 - hand, such strategies have been hampered by the lack of an adequately sensitive and specific test or tests … This review will also include a summary of the diagnostic accuracy of screening examinations/tests for … Key Question 3 What is the predictive value of screening tests for open-angle glaucoma? … Key Question 3 explores comparisons of screening/diagnostic tests to the gold/reference standards of … We acknowledge that there is no consensus on the gold standard test (or combination of tests) for the

227. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/glaucoma-screening_research-protocol.pdf
     November 16, 2010 - hand, such strategies have been hampered by the lack of an adequately sensitive and specific test or tests … This review will also include a summary of the diagnostic accuracy of screening examinations/tests … Key Question 3 What is the predictive value of screening tests for open-angle glaucoma? … Key Question 3 explores comparisons of screening/diagnostic tests to the gold/reference standards of … We acknowledge that there is no consensus on the gold standard test (or combination of tests) for the

228. Effective Health Care Program
     effectivehealthcare.ahrq.gov/health-topics/medicaid-0
     December 07, 2009 - Methods Guide for Authors of Systematic Reviews of Medical Tests: A Collaboration Between the Agency

229. Disposition of Comments Report for Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
     September 25, 2013 - LTA and the VerifyNow tests are based on light transmittance, but the VASP assay is not. … These differences result in a lack of standardization among platelet function tests. … We agree that MACE are relevant to the assessment of tests for platelet reactivity. … or combinations of genetic tests were rarely assessed.” … We agree that none of the tests considered in this review are “perfect” predictors.

230. Imaging Tests for the Staging of Colorectal Cancer | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/colorectal-cancer-staging/

231. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea_research-protocol.pdf
     March 15, 2010 - The value of the different tests and of the questionnaires and other screening tools remains unclear … There is also lack of clarity as to whether the tests can be http://www.effectivehealthcare.ahrq.gov … Pulse oximetry will be evaluated among the diagnostic tests. … Key question 3 will evaluate different screening tests and protocols. … Correlation, concordance, or agreement among tests (Not KQ 4) 2.

232. Prostate-Cancer-Therapies-Update Consumer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_consumer.pdf
     January 01, 2016 - Yes, this information is right for you if: � Your doctor* said all tests show you have localized prostate … Common tests to check for prostate cancer include: � Digital rectal exam: Your doctor inserts a finger … If the test results are not normal, your doctor may recommend more tests, such as a biopsy. … Your doctor will not do any tests to see if your cancer is growing. … If tests show your cancer is starting to grow, your doctor will talk with you about other treatment

233. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_executive.pdf
     July 01, 2011 - How do these tests compare in different subgroups of patients, based on: race, sex, body mass index, … The search strategy included terms for OSA, sleep apnea diagnostic tests, sleep apnea treatments, and … Of note, where interventions (either diagnostic tests or treatments) are not discussed, this does not … tests in selected patients) with full evaluation (by PSG). … , quality of life tests, neurocognitive tests, and blood pressure. 17 Table A.

234. Core Needle and Open Surgical Biopsy for Diagnosis of Breast Lesions — An Update to the 2009 Report | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/breast-biopsy-update/research-protocol
     September 20, 2013 - Among women screened annually for 10 years, approximately 50 percent will need additional imaging tests … Although these tests are often referred to as tests for publication bias, reasons other than publication … nonspecific and the tests noninformative. 32,33 Therefore, instead of relying on statistical tests, … Empirical evidence of design-related bias in studies of diagnostic tests. … Grading a body of evidence on diagnostic tests.

235. Disposition of Comments for CER 171 Noninvasive Testing for Coronary Artery Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/coronary-artery-disease-testing_disposition-comments.pdf
     March 29, 2016 - It would be helpful to more clearly describe the difference between functional and anatomic tests earlier … The initial description of anatomic and functional tests is on page 2 of the full report. … However, some of the unknowns regarding CMR in relation to other tests such as downstream testing, … Testing technologies examined included functional tests (i.e. … We have added a table that outlines the tests compared.

236. antibiotics-respiratory-infection-protocol-140922 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_research-protocol.pdf
     September 22, 2014 - Clinical strategies include delayed prescribing of antibiotics or use of point-of-care diagnostic tests … Examples include inflammatory tests (e.g., procalcitonin, C- reactive protein [CRP], white blood cell … Reporting bias will be assessed following EPC guidance (Appendix A), 13 using tests for funnel plot … expert in such tests to participate in reviewing the draft report. … Expert review of the point of care tests evidence review will improve the final report.

237. Colorectal-Cancer-Screening Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-screening_executive.pdf
     February 01, 2012 - What is the effectiveness of fecal DNA testing (alone or in combination with other screening tests) … to fecal immunochemical test (FIT) tests. … Finally, this review will likely be out of date as new tests and evidence supporting these tests becomes … Empirical evidence of design-related bias in studies of diagnostic tests. … Fecal multiple molecular tests to detect colorectal cancer in stool.

238. Comparative Effectiveness of Fecal DNA Testing in Screening for Colorectal Cancer in Average Risk Adults. (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-screening_disposition-comments.pdf
     February 01, 2012 - Currently, there are no fecal DNA tests approved by the FDA for screening or diagnosing of CRC. … Currently, there are no fecal DNA tests approved by the FDA for screening or diagnosing of CRC. … Failure of Health Care Professionals to Interpret Fecal Occult Blood Tests Accurately. … What are the most important issues discussed for new tests/test versions going forward? … We believe this approach should set the standard for any future CRC screening tests.

239. Screening and Diagnosis of Gestational Diabetes Mellitus | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/gestational-diabetes-screening-diagnosis/research-protocol
     December 16, 2011 - The sensitivity and specificity of these tests reflect how correctly they are able to rule in and rule … Tests with poor performance may result in patient stress, anxiety, and unnecessary investigation and … KQ1: What are the sensitivities, specificities, reliabilities, and yields of current screening tests … We will not grade the evidence on the test properties of the screening and diagnostic tests (KQ1). … "Predictive Value of Tests"/ 26.

240. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/gestational-diabetes-screening-diagnosis_research-protocol.pdf
     December 16, 2011 - The sensitivity and specificity of these tests reflect how correctly they are able to rule in and rule … Tests with poor performance may result in patient stress, anxiety, and unnecessary investigation and … KQ1: What are the sensitivities, specificities, reliabilities, and yields of current screening tests … We will not grade the evidence on the test properties of the screening and diagnostic tests (KQ1). … "Predictive Value of Tests"/ 26.