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481. Research Methods & Tools | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/research-methods
     April 01, 2022 - investigators in the EPC Program on preparing, conducting, and using systematic reviews of medical tests

482. Disposition of Comments for Comparative Effectiveness Review 130 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/preoperative-testing_disposition-comments.pdf
     January 29, 2014 - with concerns about the sizable cost of testing, overtesting and the consequences of false positive tests … (e.g., complications due to unnecessary biopsies performed to follow up false positive laboratory tests … Thank you Peer Reviewer #8 Introduction The subsection on “preoperative tests” seems to be repetitive … e.g., pain, hemorrhage, or bruising from a blood draw, exposure to ionizing radiation from imaging tests … Given the heterogeneity of tests and surgeries, almost all our evidence boils down to single studies

483. Kravitz_ECCS2012 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/kravitz_eccs2012.pdf
     January 01, 2012 - outpatients made requests for physician action. o Requests were made for:  Laboratory testing, imaging tests … for care after their visits. o Most, but not all, of the unmet expectations concerned medications, tests

484. Renal-Cancer Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/renal-cancer_research-protocol.pdf
     April 20, 2015 - or biopsy) Composite models (combination of demographics, clinical characteristics, blood/urine tests … biopsy) • Composite models (combination of demographics, clinical characteristics, blood/urine tests … .[38-39] The results of the diagnostic tests will be tabulated and sensitivity, specificity, positive … of bias • Medium risk of bias • High risk of bias Well designed and executed studies of new tests … Grading a Body of Evidence on Diagnostic Tests. In: Chang SM, Matchar DB, Smetana GW, et al, eds.

485. An analytical framework for quantifying components of variability in prescriber decisions (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/instrumental-variable-methods_research.pdf
     April 01, 2010 - Specification tests in econometrics. Econometrica 1978;46:1251- 1271. 69. Wu DM. … Alternative tests of the independance between stochastic regessors and disturbances. … These tests assume that one has available a valid IV and the test then attempts to determine whether … Tests of this sort have been proposed by Durbin, 67 Hausman, 68 and Wu. 69 One limitation of … these tests is that they assume homogeneous treatment effects.

486. Template for Reports Developed (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/c-difficile-future_research.pdf
     October 26, 2012 - Comparative data were not found for many currently used tests. … Substantial differences in false positives, that is, specificity, were not found among the tests that … Comparative data were not always available for the three currently available gene detection tests. … Comparative data were not found for many currently used tests. … Comparative data were not found for many currently used tests.

487. Liver-Cancer Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
     October 01, 2014 - liver that are clinically suspicious for HCC.4 The evaluation phase involves the use of additional tests … We excluded studies in which the reference standard involved one of the imaging tests under evaluation … Technical information for different imaging tests was abstracted.11 Assessment of Methodological Risk … We identified 274 studies that evaluated diagnostic accuracy of imaging tests. … Fifty-four studies evaluated diagnostic accuracy of imaging tests in diagnosing HCC among individuals

488. Diagnosis and Management of Gout: Current State of the Evidence (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/gout_clinician.pdf
     January 01, 2017 - One review evaluated the evidence regarding the accuracy and safety of tests used to initially diagnose … The role of clinical algorithms (which often draw upon clinical signs, symptoms, and laboratory tests … The two systematic reviews summarized here assessed the accuracy of tests to diagnose gout and also

489. Prostate-Cancer-Risk-Assessment-Genes Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/prostate-cancer-risk-assessment-genes_executive.pdf
     July 01, 2012 - Amidst substantial debate,17-23 the argument has been made for developing more accurate screening tests … In general, proposed tests with an AUC of 75 percent or less are unlikely to be clinically useful.60,61 … For one of the panels,54 we noted the development of separate tests for SNPs in steroid hormone pathway … the risk models based on SNP panels improved the AUC only marginally compared with non–SNP-based tests … Misconceptions about the use of genetic tests in populations. Lancet. 2001;357(9257):709-12.

490. Disposition of Comments for PCA3 Testing for the Diagnosis and Management of Prostate Cancer (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/prostate-cancer-test_disposition-comments.pdf
     April 01, 2013 - that have analyzed 2 or more tests in the same patients. … TEP # 13 ES-10, line 23 Refers to the PCA3 tests as "noninvasive" and "from urine." … Would it be sufficient to simply say that the tests are done using a urine sample, or to qualify the … At very low, or high specificities, the two tests will be most likely similar. … screening tests for cancer or for other diseases.

491. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - AHRQ is interested in innovations in drugs and biologics, medical devices, screening and diagnostic tests … to identification of new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests … .21 These tests may include blood tests to measure nutrient levels in the bloodstream, abdominal x-rays … or ultrasound to provide images of the abdomen, stool-sample tests to detect infection or unabsorbed … and protein, endoscopy or 4 colonoscopy to examine the inside of the intestine, and other tests

492. Topic 0502 Non-Muscle Invasive Bladder Cancer NSD FINAL_SJ (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0587-131115.pdf
     March 06, 2013 - How do the accuracies of imaging tests, cystoscopy, urine cytology, urine-based from Nominator: biomarkers

493. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0430_04-22-2011.pdf
     January 01, 2011 - ultrasound, cystoscopy, x-ray, computed tomography scan, prostate-specific antigen measurement, urodynamic tests

494. Data Points 15: Breast Cancer Diagnostic Workup: Prognostic factor testing among older women with ductal carcinoma in situ and early invasive breast cancer (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/dcis-prognostic-tests_research.pdf
     August 22, 2012 - However, rates of positive ER tests have not increased. … Rates of testing varied significantly across race groups for all tests. … However, the pat- tern of change differed between tests. … These tests provide information about the tumor’s aggressiveness, based on how it responds to external … BRCA: We identified tests for BRCA 1 and 2 in the Medicare claims data using HCPCS codes 83080, 83890

495. Colorectal-Surgery-Preparation Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/colorectal-surgery-preparation_research-protocol.pdf
     March 26, 2013 - o The same as for KQ 2a, with the additional requirement that studies report formal interaction tests … For all statistical tests, Source: http://effectivehealthcare.ahrq.gov Posted: March 26, 2013 12 … Although these tests are often referred to as tests for publication bias; reasons other than publication … smaller and larger studies, other biases, and chance, thereby rendering the interpretation of the tests … nonspecific and the tests noninformative.32,33 Therefore, instead of relying on statistical tests,

496. Urinary-Incontinence-Treatment Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/urinary-incontinence-treatment_research-protocol.pdf
     September 30, 2010 - methods—questionnaires, checklists, scales, self-reports of UI during a clinical examination, pad tests … methods—questionnaires, checklists and scales, self-reports of UI during a clinical examination, pad tests … Studies that reported absolute values of the diagnostic tests in incontinent women; 9. … Studies that did not report true and false positive and negative cases of diagnostic tests. … We will also analyze urinary continence defined as negative stress and pad tests.

497. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pregnancy_hi_impact.pdf
     January 01, 2012 - AHRQ is interested in innovations in drugs and biologics, medical devices, screening and diagnostic tests … to identification of new (and new uses of existing) pharmaceuticals, medical devices, diagnostic tests … Upon receiving a positive result from these first-trimester tests, a woman may be counseled to undergo … These confirmatory tests pose a risk of miscarriage. … , the increased patient comfort relative to invasive tests, and the ability of most any physician’s

498. Comparing the long-term and real-world effectiveness of initial management strategies for ductal carcinoma in situ (DCIS) | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/dcis-effectiveness/abstract
     November 01, 2017 - You Might Also Like Research Protocol Jul 22, 2024 Blood-based Tests

499. Chemotherapy in Advanced Colorectal Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/colorectal-cancer/abstract
     November 01, 2017 - Locally Advanced Gastric Adenocarcinoma Research Protocol Jul 22, 2024 Blood-based Tests

500. Pancreatic Diseases | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/pancreatic-diseases
     August 09, 2013 - pancreaticdiseases.html Products Research Protocol Archived August 9, 2013 Imaging Tests