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41. Diagnosis of Celiac Disease | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/celiac-disease/research
    December 01, 2019 - Promising results were reported for deamidated gliadin peptide antibodies (DGP) IgA tests (sensitivity … Evidence for algorithms using multiple tests was insufficient because of diverse results, low number … sensitivity of tTG IgA tests and excellent specificity of both tTG IgA and EmA IgA tests. … Sensitivity of DGP IgA and immunoglobulin G tests is slightly less than for tTG IgA. … Additional studies are needed to confirm the accuracy of diagnostic tests in special populations and

42. Imaging Tests for the Diagnosis and Staging of Pancreatic Adenocarcinoma | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/cancer-pancreas/research
    December 01, 2019 - EHC FAQs Home Evidence Reports Imaging Tests … SHARE: Imaging Tests … the available information on the diagnostic accuracy and clinical utility of commonly used imaging tests … accuracy, screening accuracy, clinical management, quality of life, survival, and harms of imaging tests … Project Timeline Imaging Tests for the Diagnosis and Staging of Pancreatic Adenocarcinoma Feb 27

43. Deciding Whether to Complement a Systematic Review of Medical Tests with Decision Modeling | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-decision-models/slides
    December 01, 2019 - Evidence Reports Deciding Whether to Complement a Systematic Review of Medical Tests … : Deciding Whether to Complement a Systematic Review of Medical Tests … faculty instructing investigators and clinicians interested in systematic review methods for medical tests … Project Timeline Deciding Whether To Complement a Systematic Review of Medical Tests With Decision … https://effectivehealthcare.ahrq.gov/products/methods-guidance-tests-decision-models/slides

44. Modeling to evaluate benefits and harms of new diagnostic tests compared to established diagnostic tests – uses and limitations (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/benefits-harms-modeling_research.pdf
    November 19, 2009 - Modeling to evaluate benefits and harms of new diagnostic tests compared to established diagnostic tests … Decision-analytic modelling to evaluate benefits and harms of medical tests. … To a large extent, effects of medical tests are indirect in nature. … Empirical evidence of design-related bias in studies of diagnostic tests. … Meta- analysis of diagnostic tests with imperfect reference standards.

45. Choosing the Important Outcomes for a Systematic Review of a Medical Test | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-outcomes/slides
    December 01, 2019 - faculty instructing investigators and clinicians interested in systematic review methods for medical tests … https://effectivehealthcare.ahrq.gov/products/methods-guidance-tests-outcomes/slides  

46. Assessing Applicability of Medical Test Studies in Systematic Reviews | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-applicability/slides
    December 01, 2019 - faculty instructing investigators and clinicians interested in systematic review methods for medical tests … https://effectivehealthcare.ahrq.gov/products/methods-guidance-tests-applicability/slides

47. Options for Summarizing Medical Test Performance in the Absence of a Gold Standard | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-performance/slides
    December 01, 2019 - faculty instructing investigators and clinicians interested in systematic review methods for medical tests … https://effectivehealthcare.ahrq.gov/products/methods-guidance-tests-performance/slides

48. Introduction to the Methods Guide for Medical Test Reviews | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-introduction/slides
    December 01, 2019 - faculty instructing investigators and clinicians interested in systematic review methods for medical tests … https://effectivehealthcare.ahrq.gov/products/methods-guidance-tests-introduction/slides

49. Meta-analysis of Test Performance Evidence When There is a “Gold Standard” | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-metaanalysis/slides
    December 01, 2019 - faculty instructing investigators and clinicians interested in systematic review methods for medical tests … https://effectivehealthcare.ahrq.gov/products/methods-guidance-tests-metaanalysis/slides

50. Assessing Risk of Bias as a Domain of Quality in Medical Test Studies | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-bias/slides
    December 01, 2019 - faculty instructing investigators and clinicians interested in systematic review methods for medical tests … https://effectivehealthcare.ahrq.gov/products/methods-guidance-tests-bias/slides  

51. Diagnostic Imaging | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/health-topics/diagnostic-imaging?page=0
    October 25, 2024 - Certain tests involve exposure to a small amount of radiation . … For some imaging tests, doctors insert a tiny camera attached to a long, thin tube into your body. … Metastatic Breast Cancer Systematic Review Archived September 23, 2014 Imaging Tests … Pancreatic Adenocarcinoma Systematic Review Archived September 10, 2014 Imaging Tests … for Metastatic Breast Cancer Research Protocol Archived August 9, 2013 Imaging Tests

52. Diagnostic Imaging | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/health-topics/diagnostic-imaging
    October 25, 2024 - Certain tests involve exposure to a small amount of radiation . … For some imaging tests, doctors insert a tiny camera attached to a long, thin tube into your body. … Metastatic Breast Cancer Systematic Review Archived September 23, 2014 Imaging Tests … Pancreatic Adenocarcinoma Systematic Review Archived September 10, 2014 Imaging Tests … for Metastatic Breast Cancer Research Protocol Archived August 9, 2013 Imaging Tests

53. Genetic Testing for Developmental Disabilities, Intellectual Disability, and Autism Spectrum Disorder | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/genetic-testing-developmental-disabilities/technical-brief
    December 01, 2019 - Genetic tests (e.g., array comparative genomic hybridization, sequencing) are rapidly diffusing into … An urgent need exists for a better understanding of these tests and their clinical utility. … Purpose This Technical Brief collects and summarizes information on genetic tests clinically available … It also identifies, but does not systematically review, existing evidence addressing the tests' clinical … National Center for Biotechnology Information's Genetic Testing Registry (GTR) to identify genetic tests

54. Prenatal Testing | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/health-topics/prenatal-testing
    Some routine tests during pregnancy also check on your health. … Throughout your pregnancy, your health care provider may suggest a number of other tests, too. … Results of routine tests Some tests are screening tests. … Based on screening test results, your doctor might suggest diagnostic tests. … Diagnostic tests confirm or rule out health problems in you or your baby.

55. Blood-based Tests for Multiple Cancer Screening: A Systematic Review | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/cell-free-dna/protocol
    July 01, 2024 - Blood tests used in combination with other tests such as imaging are eligible. … on cancers with standards of care screening tests. … However, they may be useful for describing the landscape of current tests and determining which tests … , with few tests evaluated by more than one study. … For KQ 3, we will consider the pace of evolution and enhancements of the tests evaluated, whether tests

56. Evaluating Practices and Developing Tools for Comparative Effectiveness Reviews of Diagnostic Test Accuracy: Methods for the Joint Meta-Analysis of Multiple Tests (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/diagnostic-tests-accuracy_research.pdf
    January 01, 2013 - two tests. … We use M to denote the number of tests. … The Case of Two Tests Consider a meta-analysis of two tests (indexed by m ) and data from K studies … The Case of Three or More Tests One can extend the models to M > 2 tests that have been applied in … Humerus and tests. Med Decis Making.

57. Blood-based Tests for Multiple Cancer Screening: A Systematic Review | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/cell-free-dna/draft-report
    January 01, 2025 - Home Evidence Reports Blood-based Tests … SHARE: Blood-based Tests … was to assess the accuracy, benefits, and harms of screening with blood-based multicancer screening tests … The sensitivity, specificity, and positive predictive value varied widely across tests, subgroups, and … 2025 Internet Citation: Draft Comments: Blood-based Tests

58. Blood-based Tests for Multiple Cancer Screening: A Systematic Review (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cell-free-dna-draft-report.pdf
    December 01, 2024 - for rare cancers. 1.1.2 Multicancer Screening Tests Multicancer screening tests (MCST) are assays … Some test developers refer to such tests as multi-cancer early detection (MCED) tests or multicancer … detection tests. … and across time as tests evolve. … Laboratory Developed Tests. 2024.

59. Editorial. Methods Guide for Authors of Systematic Reviews of Medical Tests: A Collaboration Between the Agency for Healthcare Research and Quality (AHRQ) and the Journal of General Internal Medicine | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/methods-guide-editorial/methods
    December 01, 2019 - Methods Guide for Authors of Systematic Reviews of Medical Tests: A Collaboration Between the Agency … Clinicians obtain medical tests for a number of non-overlapping reasons. … An additional two workgroups addressed issues unique to genetic and prognostic tests. … Medical tests. White paper series; Nov. 16, 2009. … https://effectivehealthcare.ahrq.gov/products/medical-tests-series/overview/ .

60. Hepatitis Testing | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/health-topics/hepatitis-testing
    There are blood tests for each type of viral hepatitis. … Some tests check for antibodies to the virus. … Other blood tests look for parts of the virus, such as proteins or genetic material. … Some tests show that you have the infection now. … Other tests show that you have had it at some time, or that you have immunity to it.