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321. breast-biopsy-update-130920 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_research-protocol.pdf
     September 20, 2013 - Among women screened annually for 10 years, approximately 50 percent will need additional imaging tests … ● Comparators (reference standard and comparator index tests) For test performance outcomes … Although these tests are often referred to as tests for publication bias, reasons other than publication … nonspecific and the tests noninformative.32, 33 Therefore,  instead of relying on statistical tests … Grading  a  body  of  evidence  on  diagnostic  tests.  

322. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hyperactivity-disorder-protocol.pdf
     November 10, 2024 - Questions The literature for the review on diagnosing ADHD in adults will use a combination of known tests … negatives); unintended consequences and impact associated with diagnosing ADHD Provider opinion of tests … Included ADHD tests will not be limited to a set of pre-specified tools; instead, the review will document … A systematic review of the utility of continuous performance tests among adults with ADHD. … tiab] OR diagnosis[tiab] OR diagnostic[tiab] OR diagnosed[tiab] OR Measure [tiab] OR test[tiab] OR tests

323. Diagnosis of Attention-Deficit/Hyperactivity Disorder in Adults: A Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hyperactivity-disorder-protocol-amendment.pdf
     January 08, 2025 - Questions The literature for the review on diagnosing ADHD in adults will use a combination of known tests … negatives); unintended consequences and impact associated with diagnosing ADHD Provider opinion of tests … Included ADHD tests will not be limited to a set of pre-specified tools; instead, the review will document … A systematic review of the utility of continuous performance tests among adults with ADHD. … tiab] OR diagnosis[tiab] OR diagnostic[tiab] OR diagnosed[tiab] OR Measure [tiab] OR test[tiab] OR tests

324. Diagnosis of Attention-Deficit/Hyperactivity Disorder in Adults: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/hyperactivity-disorder/protocol
     February 01, 2025 - Questions The literature for the review on diagnosing ADHD in adults will use a combination of known tests … negatives); unintended consequences and impact associated with diagnosing ADHD Provider opinion of tests … Included ADHD tests will not be limited to a set of pre-specified tools; instead, the review will document … A systematic review of the utility of continuous performance tests among adults with ADHD. … [tiab] OR diagnosis[tiab] OR diagnostic[tiab] OR diagnosed[tiab] OR Measure [tiab] OR test[tiab] OR tests

325. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0174_10-20-2009.pdf
     January 01, 2009 - What tests and measures have been used to determine outcomes (e.g., for strength – manual muscle test … What are the psychometric properties of these tests and measures (reliability, validity, minimal clinically

326. Skin Conditions | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/skin-conditions?page=1
     August 23, 2010 - Research Protocol Archived June 28, 2010 Comparative Effectiveness of Non-Invasive Diagnostic Tests … Systematic Review Archived February 9, 2006 Effectiveness of Noninvasive Diagnostic Tests

327. Meta-analysis of Test Performance Evidence When There is a “Gold Standard” Reference Standard (ppt file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/medical-test-reviews-meta-analysis.ppt
     June 01, 2012 - Empirical evidence of design-related bias in studies of diagnostic tests. … Diagnostic tests 4: likelihood ratios. BMJ 2004 Jul 17;329(7458):168-9. … Exploring sources of heterogeneity in systematic reviews of diagnostic tests. … Exploring sources of heterogeneity in systematic reviews of diagnostic tests. … Empirical evidence of design-related bias in studies of diagnostic tests.

328. Meta-analysis of Test Performance Evidence When There is a “Gold Standard” Reference Standard (ppt file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/medical-test-reviews-meta-analysis.ppt
     June 01, 2012 - Empirical evidence of design-related bias in studies of diagnostic tests. … Diagnostic tests 4: likelihood ratios. BMJ 2004 Jul 17;329(7458):168-9. … Exploring sources of heterogeneity in systematic reviews of diagnostic tests. … Exploring sources of heterogeneity in systematic reviews of diagnostic tests. … Empirical evidence of design-related bias in studies of diagnostic tests.

329. Technical Brief 13: Gene Expression Profiling for Predicting Outcomes in Stage II Colon Cancer (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_technical-brief.pdf
     December 01, 2012 - Given the additional studies on tests reported in that publication and the emergence of new tests, followup … Food and Drug Administration (FDA) status of these tests? … • Currently, how widely used are these tests? Guiding Question 3. … Currently, how Widely Used are These Tests? … ACCE Model Process for Evaluating Genetic Tests.

330. Bladder-Cancer-Non-Muscle-Invasive Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/bladder-cancer-non-muscle-invasive_research-protocol.pdf
     July 21, 2014 - survival rates from 63 to 15 percent).7 Diagnosis and surveillance of bladder cancer A number of tests … Many of the tests are investigational. … There are five diagnostic biomarker tests approved by the FDA for diagnosis or surveillance of bladder … The CxBladder™ test, which tests for five specific mRNA biomarkers, is a “Laboratory Developed Test” … and tests with high false negative rates could lead to missed diagnoses.

331. Colorectal-Cancer-Staging Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_executive.pdf
     September 01, 2014 - 1 Comparative Effectiveness Review Number 142 Imaging Tests for the Staging of Colorectal Cancer … Studies must have directly compared the tests with each other and with a reference standard; all tests … obsolete and experimental imaging tests. … See the answer to Key Question 1d for harms associated with any use of these imaging tests. … Imaging Tests for the Staging of Colorectal Cancer. Comparative Effectiveness Review No. 142.

332. Laboratory Biomarkers for Iron Deficiency Anemia in Late Stage Chronic Kidney Disease | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/chronic-kidney-disease-anemia-2011/research-protocol
     December 01, 2019 - Since test results have little direct impact on patient-relevant outcomes, the utility of medical tests … Although overarching studies that assess the overall impact of tests on the clinical management process … What are the adverse effects or harms associated with the treatments guided by tests of iron status? … A meta-analysis of diagnostic tests, such as summary receiver operating curve, will be undertaken when … (if all the other kidney tests are normal, there is no CKD) CKD stage 2: a GFR between 60 and 90 ml

333. Comparative Effectiveness of Noninvasive Technologies for the Diagnosis of Coronary Artery Disease (CAD) in Women | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/cad-women-diagnosis/research-protocol
     December 01, 2019 - predictive value in women and that a positive ECG result in women indicates that further diagnostic tests … However, neither one of these tests is applicable to the symptomatic population under consideration in … To explore additional sources of potential bias, we will also record whether the diagnostic tests were … interpreted in a blinded fashion; that is, without knowledge of results of other diagnostic tests or … Radiation risk from coronary artery disease imaging: how do different diagnostic tests compare?

334. SEAD Submission Form for Management of Attention-Deficit/Hyperactivity Disorder in Adults: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/form/management-adhd-adults/sead
     January 01, 2025 - documents, please reference the main product: Draft Comments January 22, 2025 Blood-based Tests … to Prevent Hospital-Acquired Infections Research Protocol July 22, 2024 Blood-based Tests … You Might Also Like Draft Comments Jan 22, 2025 Draft Comment Form for Blood-based Tests

335. SEAD Submission Form for Diagnosis of Attention-Deficit/Hyperactivity Disorder in Adults: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/form/hyperactivity-disorder/sead
     January 01, 2025 - documents, please reference the main product: Draft Comments January 22, 2025 Blood-based Tests … to Prevent Hospital-Acquired Infections Research Protocol July 22, 2024 Blood-based Tests … You Might Also Like Draft Comments Jan 22, 2025 Draft Comment Form for Blood-based Tests

336. Screening for Hepatitis C | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/hepatitis-c-screening/research-protocol
     December 01, 2019 - Clarity: KQ 1a: “asymptomatic” to “asymptomatic adults without known abnormal liver function tests … parts: Does screening for HCV infection in nonpregnant adults without known abnormal liver function tests … posting of the KQs, we decided to exclude the following from our review: Fibroscan® and breath tests … individuals without signs or symptoms suggestive of liver disease or known abnormal liver function tests … We will use standard x 2 tests to assess the presence of statistical heterogeneity among studies and

337. Evidence-based Practice | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/evidence-based-practice
     November 04, 2021 - Chapter June 1, 2012 Chapter 4: Effective Search Strategies for Systematic Reviews of Medical Tests … Chapter June 1, 2012 Chapter 10: Deciding Whether To Complement a Systematic Review of Medical Tests

338. Serum-Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma Cell Dyscrasias | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/plasma-cell-dyscrasias-sflc-assay/research-protocol
     December 01, 2019 - The standard tests have limited efficacy for the diagnosis of PCDs that are characterized predominantly … the SFLC assay as a screening and initial diagnostic tool for PCD could eliminate the need for urine tests … when combined with serum electrophoresis and serum immunofixation and compared with the traditional tests … Question 2 When compared with traditional tests, how well does the SFLC assay independently predict … If the studies do not directly compare the tests of interest, we will use network analysis to estimate

339. Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/antiplatelet-treatment/research
     December 01, 2019 - evaluated the analytic validity, prognostic value, and comparative effectiveness of two types of medical tests … analytic validity, prognostic ability for intermediate (platelet reactivity) or clinical outcomes, use of tests … Medical Care for Adults with Down Syndrome Research Protocol Jul 22, 2024 Blood-based Tests

340. X-Rays | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/x-rays?page=1
     May 18, 2011 - Research Protocol Archived June 28, 2010 Comparative Effectiveness of Non-Invasive Diagnostic Tests … Systematic Review Archived February 9, 2006 Effectiveness of Noninvasive Diagnostic Tests