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141. Diagnostic Imaging | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/diagnostic-imaging?page=1
     September 13, 2012 - They include X-rays CT scans Nuclear medicine scans MRI scans Ultrasound Many imaging tests … Certain tests involve exposure to a small amount of radiation . … For some imaging tests, doctors insert a tiny camera attached to a long, thin tube into your body. … Risk Adults Systematic Review Archived February 13, 2012 Noninvasive Diagnostic Tests … Research Protocol Archived June 28, 2010 Comparative Effectiveness of Non-Invasive Diagnostic Tests

142. 13-MDM347013 30..38 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/outcomes-testing-evaluation_research.pdf
     January 01, 2009 - based on an understanding of how tests can benefit or harm patients. … , such as the decision to order more tests or to start, stop, or modify treatment. … to undergoing other tests or no testing at all. … This requires an understanding of how tests can affect patient outcome. … Various randomized designs can be used to evaluate medical tests.

143. 13-MDM347013 30..38 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/whitepaper4-bossuyt02262010-2.pdf
     January 01, 2009 - based on an understanding of how tests can benefit or harm patients. … , such as the decision to order more tests or to start, stop, or modify treatment. … to undergoing other tests or no testing at all. … This requires an understanding of how tests can affect patient outcome. … Various randomized designs can be used to evaluate medical tests.

144. MRI Scans | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/mri-scans
     April 28, 2015 - Metastatic Breast Cancer Systematic Review Archived September 23, 2014 Imaging Tests … Pancreatic Adenocarcinoma Systematic Review Archived September 10, 2014 Imaging Tests … for Metastatic Breast Cancer Research Protocol Archived August 9, 2013 Imaging Tests … breast cancer Systematic Review Archived February 13, 2012 Noninvasive Diagnostic Tests … Systematic Review Archived February 9, 2006 Effectiveness of Noninvasive Diagnostic Tests

145. Methods Guide for Medical Test Reviews - Editorial (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guide-editorial_methods.pdf
     July 01, 2012 - Reviews - Editorial E-1 Editorial Methods Guide for Authors of Systematic Reviews of Medical Tests … Clinicians obtain medical tests for a number of non-overlapping reasons. … An additional two workgroups addressed issues unique to genetic and prognostic tests. … Medical tests. White paper series; Nov. 16, 2009. … Methods guide for authors of systematic reviews of medical tests: a collaboration between the Agency

146. PowerPoint Presentation (ppt file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/medical-test-reviews-options-summarizing.ppt
     June 01, 2012 - Index and reference tests are correlated within strata of disease. … A probabilistic model for the comparison of diagnostic tests. … Meta-analysis of diagnostic tests with imperfect reference standards. … A probabilistic model for the comparison of diagnostic tests. … Meta-analysis of diagnostic tests with imperfect reference standards.

147. PowerPoint Presentation (ppt file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/medical-test-reviews-options-summarizing.ppt
     June 01, 2012 - Index and reference tests are correlated within strata of disease. … A probabilistic model for the comparison of diagnostic tests. … Meta-analysis of diagnostic tests with imperfect reference standards. … A probabilistic model for the comparison of diagnostic tests. … Meta-analysis of diagnostic tests with imperfect reference standards.

148. Appendixes: Blood-based Tests for Multiple Cancer Screening: A Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cell-free-dna-appendices.pdf
     May 22, 2024 - Appendixes: Blood-based Tests for Multiple Cancer Screening: A Systematic Review Appendix A. … Detailed inclusion and exclusion criteria for systematic review on blood-based tests for multiple cancer … cancer; tests using any analytes with any technology are eligible … • Blood tests used in combination with other tests such as imaging are eligible. … KQ 5 • Tests or interventions not performed as a result of a positive MCST.

149. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0068_01-30-2009.pdf
     January 01, 2009 -  Although immunologic laboratory tests can have great utility in the diagnosis and management of … The nominator has expressed interest in the diagnostic accuracy of the ANA and RF tests in children …  In addition, because these tests are known to have a low predictive value in this population, … Because these tests are used as prognostic indicators, information on the prognostic significance of … the tests may also be helpful to include in a report

150. Imaging for the Pretreatment Staging of Small Cell Lung Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/lung-cancer-staging/research
     December 01, 2019 - Review methods We included studies of pertinent imaging tests on SCLC patients before treatment that … principally due to failure to report on patient selection, reader blinding to results of comparator tests … The most frequently reported imaging tests were MDCT, [ 18 F]-fluorodeoxyglucose (FDG) PET/CT, and bone … Research gaps include the dearth of evidence on several tests of interest (particularly MRI, EBUS, EUS … , and PET/MRI), a lack of study designs to compare tests on patient-oriented outcomes such as survival

151. Fatty Liver Disease | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/fatty-liver-disease
     Your doctor may suspect that you have it if you get abnormal results on liver tests that you had for … To make a diagnosis, your doctor will use Your medical history A physical exam Various tests, … including blood and imaging tests , and sometimes a biopsy As part of the medical history, your … condition that causes your skin and whites of your eyes to turn yellow You will likely have blood tests … , including liver function tests and blood count tests .

152. Hepatic-Fibrosis White-Paper (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hepatic-fibrosis_white-paper.pdf
     April 01, 2014 - However, our review of diagnostic blood tests 5 had limitations. … Optimization and robustness of blood tests for liver fibrosis and cirrhosis. … Routine blood tests to predict liver fibrosis in chronic hepatitis C. … Optimization and robustness of blood tests for liver fibrosis and cirrhosis. … Routine blood tests to predict liver fibrosis in chronic hepatitis C.

153. Hi Les, (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rtc-design-principles_research.pdf
     January 01, 2009 - Hi Les, Medical Tests—White Paper Series Using the Principles of Randomized Controlled … Pap tests takes next priority. … Randomised comparisons of medical tests: sometimes invalid, not always efficient. … Various randomized designs can be used to evaluate medical tests. … Comparative accuracy: assessing new tests against existing diagnostic pathways.

154. Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/antiplatelet-treatment/research-protocol
     December 01, 2019 - variants and phenotypic tests for platelet reactivity. … standardized than tests of reactivity. … The figure illustrates that results of genetic tests for CYP2C19 or of phenotypic tests of platelet reactivity … Various randomized designs can be used to evaluate medical tests. … of platelet reactivity as “phenotypic tests” (see above).

155. Liver Diseases | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/liver-diseases
     October 23, 2014 - Tests such as imaging tests and liver function tests can check for liver damage and help to diagnose … April 2, 2014 Impact of Contacting Study Authors on Systematic Review Conclusions: Diagnostic Tests

156. Cancer-Pancreas Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
     September 01, 2014 - For any KQs comparing two or more tests, the study must have compared both tests to a reference standard … We also used a minimum of 10 for KQ3b on patient perspectives of imaging tests. … , the harms of concern are different for different tests. … after different tests. … Imaging Tests for the Diagnosis and Staging of Pancreatic Adenocarcinoma.

157. Diagnosis of Celiac Disease | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/celiac-disease/research-protocol
     December 01, 2020 - A number of diagnostic methods have been developed; they include various serology tests, HLA typing, … Serology tests include Anti-gliadin antibodies (AGA), IgA & IgG; Anti-tissue Transglutaminase (tTG), … These tests are often used by providers as a panel in order to increase specificity and prevent false … positives that are associated with tests that don’t work well under varying circumstances. … The diagnosis of celiac disease is further complicated by the limitations of the various tests, lack

158. Methods Guide for Medical Test Reviews Chapter 10 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-decision-models_methods.pdf
     July 01, 2012 - Reviews Chapter 10 10-1 Chapter 10 Deciding Whether To Complement a Systematic Review of Medical Tests … Therefore, test performance is typically not sufficient for assessing the usefulness of medical tests … Medical tests exert most of their effects in an indirect way. … detected by the more sensitive tests may not have the same treatment response. … Evaluating new screening tests for breast cancer. BMJ 2006; 332(7543):678-679. 20.

159. Appendicitis Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/appendicitis_research-protocol.pdf
     December 09, 2013 - The test performance of clinical signs and symptoms, laboratory tests, or imaging tests may be modified … or decision rules, imaging tests, nuclear imaging studies, diagnostic laparoscopy. … Comparators Alternative tests or test combinations (as listed above), clinical observation. … Although these tests are often referred to as tests for publication bias; reasons other than publication … nonspecific and the tests noninformative.64, 65 Therefore, instead of relying on statistical tests,

160. Gene Expression Profiling for Predicting Outcomes in Patients With Stage II Colon Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/colon-cancer-gene-profiling/research-protocol
     December 01, 2019 - Given the additional studies on tests reported in that publication and the emergence of new tests, follow-up … Food and Drug Administration (FDA) status of these tests? … Currently, how widely used are these tests? … Impact of Gene Expresion Profiling Tests on Breast Cancer Outcomes. … Genomic Testing: ACCE Model Process for Evaluating Genetic Tests.