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121. Diagnostic Imaging | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/diagnostic-imaging?page=2
     April 14, 2010 - They include X-rays CT scans Nuclear medicine scans MRI scans Ultrasound Many imaging tests … Certain tests involve exposure to a small amount of radiation . … For some imaging tests, doctors insert a tiny camera attached to a long, thin tube into your body. … Systematic Review Archived February 9, 2006 Effectiveness of Noninvasive Diagnostic Tests

122. Prostate Cancer Screening | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/prostate-cancer-screening
     Researchers are studying different tests to find those with the fewest risks and most benefits. … If your screening results are abnormal, your doctor may do more tests, such as an ultrasound , MRI … may not improve your health or help you live longer The results can sometimes be wrong Follow-up tests … You and your doctor should discuss your risk for prostate cancer, the pros and cons of the screening tests

123. Screening for Glaucoma: Comparative Effectiveness | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/glaucoma-screening/research
     December 01, 2019 - We also summarized the accuracy of diagnostic tests. … For diagnostic test accuracy, we included case control studies, designs in which tests were performed … , optic nerve damage, visual field progression, and harms as well as sensitivity and specificity of tests … One systematic review evaluated the diagnostic accuracy of screening tests for OAG. … We identified 4,960 studies, of which 83 studies addressing the accuracy of screening tests were eligible

124. Diagnosis of Right Lower Quadrant Pain and Suspected Acute Appendicitis | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/appendicitis/research-protocol
     December 01, 2019 - The test performance of clinical signs and symptoms, laboratory tests, or imaging tests may be modified … treatment for tests used to diagnose RLQ pain and suspected acute appendicitis? … or decision rules, imaging tests, nuclear imaging studies, diagnostic laparoscopy. … Although these tests are often referred to as tests for publication bias; reasons other than publication … nonspecific and the tests noninformative. 64,65 Therefore, instead of relying on statistical tests,

125. Methods Guide for Medical Test Reviews Chapter 3 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-outcomes_methods.pdf
     July 01, 2012 - tests, and prognostic tests, although prognostic tests are also discussed in Chapter 11. … It is likely that the direct health effects of screening tests are less than in tests used for diagnosis … and prognosis: screening tests are generally designed to be less invasive than tests used to make diagnoses … Example of a Diagnostic Test We differentiate diagnostic tests from screening tests largely by the population … effects than tests used for other purposes.

126. Breast Abnormalities Update Surveillance Assessment_CER 47_Low (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_surveillance.pdf
     September 01, 2012 - Breast Abnormalities Update Surveillance Assessment_CER 47_Low CER #47: Noninvasive Diagnostic Tests … .............................................................. 5 1 Noninvasive Diagnostic Tests … Introduction Comparative Effectiveness Review (CER) #47, Noninvasive Diagnostic Tests for Breast … original release until September 2012, we received any FDA updates on the included treatments and tests … Noninvasive Diagnostic Tests for Breast Abnormalities: Update of a 2006 Review.

127. Methods Guide for Medical Test Reviews Chapter 2 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-topics_methods.pdf
     July 01, 2012 - Chapter 2 2-1 Chapter 2 Developing the Topic and Structuring Systematic Reviews of Medical Tests … Due to the indirect impact of medical tests on clinical outcomes, reviewers need to identify which … This paper highlights challenges unique to systematic reviews of medical tests. … such tests in clinical decisionmaking, such as guiding the decision to perform a biopsy. … Are tests’ cases subsequently confirmed by same reference standard? 6.

128. Methods Guide for Medical Test Reviews Chapter 6 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-applicability_methods.pdf
     July 01, 2012 - Evidence, Agency for Healthcare Research and Quality, Rockville, Maryland Abstract Use of medical tests … should be guided by research evidence about the accuracy and utility of those tests in clinical care … To make informed decisions about medical tests, whether diagnostic, prognostic, or those used to monitor … Rapidly Evolving Tests A third challenge, especially relevant to medical tests, is that, even more than … How and by whom tests are conducted in practice and in studies.

129. Methods Guide for Medical Test Reviews Chapter 9 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-performance_methods.pdf
     July 01, 2012 - Assess the concordance of difference tests instead of test accuracy. … Tests With Correlated Results Within the Strata of the Disease When the two tests are correlated conditional … A probabilistic model for the comparison of diagnostic tests. … Meta- analysis of diagnostic tests with imperfect reference standards. … Evaluation of diagnostic tests without gold standards.

130. Methods Guide for Medical Test Reviews Chapter 7 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-grading_methods.pdf
     July 01, 2012 - Our focus will be on diagnostic tests, meaning tests that are used in the diagnostic and management … This is particularly challenging when tests are used as a part of an algorithm. … Tests that are more invasive will naturally have greater harms. … Key Points • One can use GRADE for diagnostic tests. … Impact of Gene Expression Profiling Tests on Breast Cancer Outcomes.

131. Diagnosis and Treatment of Clinical Alzheimer's-Type Dementia | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/alzheimers-type-dementia/research
     October 01, 2022 - Key Messages Many brief cognitive tests were highly (>0.8) sensitive and specific distinguishing CATD … To summarize evidence on: (1) the accuracy of brief cognitive tests for identifying clinical Alzheimer … Multiple brief cognitive tests were highly sensitive and specific (>0.8) for distinguishing CATD from … , amyloid positron emission tomography (PET), fluorodeoxyglucose (FDG)-PET, and combinations of CSF tests … Brief Cognitive Tests for Distinguishing Clinical Alzheimer-Type Dementia From Mild Cognitive Impairment

132. genetic-testing-developmental-disabilities-protocol-140930 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/genetic-testing-developmental-disabilities_research-protocol.pdf
     September 30, 2014 - Interventions: Genetic tests for diagnosing DDs This Technical Brief only includes tests that are available … We anticipate identifying a large number of tests of interest from GTR. … syndrome,” 155 tests linked to “fragile X syndrome,” and 142 tests linked to “Prader-Willi syndrome … Most of these tests are LDTs. We will also search two other U.S. … for DDs, and new technologies or tests under development.

133. Plasma-Cell-Dyscrasias-Sflc-Assay Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_executive.pdf
     August 01, 2012 - PCDs are a heterogeneous group of disorders that require a panel of tests for accurate diagnosis. … (i.e., SFLC assay in addition to traditional testing) and the comparator (traditional tests alone) … (serum or urine tests [SPEP, UPEP, SIFE, or UIFE], bone marrow evaluation, or skeletal survey). … No direct comparisons between the SFLC assay and traditional tests were performed. … , compared with traditional tests alone, in undiagnosed patients with suspected PCD?

134. COPD | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/copd
     October 11, 2019 - breath, especially with physical activity Wheezing Chest tightness Doctors use lung function tests … , imaging tests, and blood tests to diagnose COPD.

135. Pancreatic Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/pancreatic-cancer
     September 23, 2014 - Doctors use a physical exam, blood tests, imaging tests, and a biopsy to diagnose it. … pancreaticcancer.html Products Systematic Review Archived September 23, 2014 Imaging Tests … of Pancreatic Adenocarcinoma Research Protocol Archived August 9, 2013 Imaging Tests

136. Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma Cell Dyscrasias | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/plasma-cell-dyscrasias-sflc-assay/research
     December 01, 2019 - regarding the role of the serum free light chain (SFLC) assay in diagnosis as an adjunct to traditional tests … standardized protocol was used to extract details on designs, diagnoses, interventions (diagnostic tests … The comparison and outcomes of interest were the role of the SFLC assay as an adjunct to traditional tests … for diagnosis of PCDs, and the effectiveness of the SFLC assay versus traditional tests for studying … therapeutic decisionmaking compared with traditional testing alone and as a substitute for other diagnostic tests

137. Diagnosis and Treatment of Clinical Alzheimer's-type Dementia (CATD) (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/catd-protocol-draft_0.pdf
     November 02, 2018 - For diagnostic tests, SOE will be graded for the 1-2 most commonly reported validated tests for each … of the following categories: global cognitive screening tests, global multidomain cognitive tests, … memory, MRI, PET, and CSF tests. … ]) KQ 8: Brain imaging tests in contemporary use (CT, MRI, PET, fMRI, SPECT), CSF tests, blood tests … tests, memory, MRI, PET imaging, and CSF tests.

138. Diagnosis and Treatment of Clinical Alzheimer's-type Dementia (CATD) | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/alzheimers-type-dementia/protocol
     August 01, 2020 - For diagnostic tests, SOE will be graded for the 1-2 most commonly reported validated tests for each … , MRI, PET, and CSF tests. … ]) KQ 8: Brain imaging tests in contemporary use (CT, MRI, PET, fMRI, SPECT), CSF tests, blood tests … tests, memory, MRI, PET imaging, and CSF tests. … these tests may be useful.

139. Disposition of Comments for Technical Brief 23 Genetic Testing (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/genetic-testing-developmental-disabilities_disposition-comments.pdf
     June 30, 2015 - polymorphism (SNP)-array tests. … tests.” … So, these 56 tests are not one same test. … 113 different tests. … represent newer versions of tests.

140. Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma Cell Dyscrasias: Future Research Needs (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay-future_research.pdf
     September 01, 2012 - , compared with traditional tests, in individual PCDs with regard to: a. … Can it diagnose or detect disease progression earlier than traditional tests? c. … and how do they compare with the SFLC test with and without traditional tests? … Can it diagnose or detect disease progression earlier than traditional tests? c. … and how do they compare with the SFLC test with and without traditional tests?