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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/brca-related-cancer-risk-assessment-genetic-counseling-testing
April 11, 2024 - Final Research Plan
BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing … What are the adverse effects of: 3a) risk assessment, 3b) genetic counseling, 3c) genetic testing, and … This may include testing other family members at higher risk before testing the index patient, including … men, in addition to the potential benefits and harms of testing family members of the index case. … What is the diagnostic accuracy of single vs. multigene panel testing for detecting pathogenic BRCA1
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/brca-related-cancer-risk-assessment-genetic-counseling-testing
January 18, 2024 - Draft Research Plan
BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing … §Genetic testing may be done on the index patient, a relative with cancer, or a relative with highest … What are the adverse effects of: 3a) risk assessment, 3b) genetic counseling, 3c) genetic testing, and … This may include testing other family members at higher risk before testing the index patient, including … men, in addition to the potential benefits and harms of testing for family members of the index case
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/qX9C7hyCBCNRjptQNCa_37
December 01, 2013 - Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-related Cancer in Women
December … If testing would be useful, women should receive
genetic testing for BRCA mutations. (2) Women
whose … BRCA testing in women who are not at risk has the potential for significant harms. … It also can help her make an informed decision about whether to have genetic testing. … BRCA testing
Examining cells for changing to the
BRCA1 and BRCA2 genes.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/xbYLYNJZ5zJXj-W4DNyxyb
June 20, 2019 - Exercise Tolerance Testing To Screen for Coronary Heart Disease: A Systematic Review for the Technical … This article describes the findings on exercise tolerance
testing only. … value of exercise tolerance testing in
asymptomatic women (42, 43). … Exercise Tolerance Testing before Beginning an Exercise
Program
Exercise tolerance testing is frequently … The role of exercise testing in screen-
ing for coronary artery disease.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/y3mQMyN2Y8mxKvPPXjM6kV
August 13, 2019 - Clinical Summary: Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer … Clinical Summary: Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer … Grade: B
Do not perform routine risk assessment, genetic counseling,
or genetic testing. … and harms of
genetic testing, interpretation of results after testing, and discussion of management … Genetic Testing
Tests for BRCA1/2 mutations are highly sensitive and specific for known mutations.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing
August 20, 2019 - and harms of genetic testing, interpretation of results after testing, and discussion of management … and harms of genetic testing, interpretation of results after testing, and discussion of management … Genetic Testing
Testing for BRCA1/2 mutations should be performed only when an individual has personal … evaluated population-based BRCA1/2 mutation testing vs family history–based testing. 75 Results showed … BRCA1 gene testing.
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/lynch-syndrome-related-cancer-adults-risk-assessment-genetic-counseling-testing
February 02, 2023 - Research Plan
Lynch Syndrome-Related Cancer in Adults: Risk Assessment, Genetic Counseling, and Genetic Testing … In asymptomatic adults, does risk assessment, genetic counseling, and genetic testing for pathogenic … What are the harms associated with genetic testing for pathogenic variants associated with Lynch syndrome … Does genetic counseling (related to genetic testing for Lynch syndrome–related cancer) improve patient … modalities; and testing of tumors
KQs 4, 5: Chemotherapy, radiation therapy, and natural therapies
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/MzHhsgTBL37rRvvJfkfgMZ
August 20, 2019 - (Includes testing other high-risk family members, including men, before testing the index patient and … Approaches
BRCA1/2 mutation testing 1 RCT (n = 1034) Universal testing of
Ashkenazi Jews for
founder … family history–based testing. … testing. … gene testing.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing
August 24, 2017 - Final Research Plan
BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing … counseling prior to testing. … Testing may be done on the index patient, a relative with cancer, or a relative with highest risk, as … Women who undergo genetic testing may have benign results or likely benign, or they may have a result … (Approaches include testing other high-risk family members, including men, before testing the index patient
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan11/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing-2013
December 15, 2012 - Final Research Plan
BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing … Among patients with an increased risk of a BRCA mutation, testing will categorize individuals as BRCA … * Clinically significant deleterious mutations of BRCA1 or BRCA2.
** Testing may be done … , interpretation of results after testing, and discussion of management options. … Comparisons
KQs 1 and 3: Risk assessment and genetic testing versus none.
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing
August 20, 2019 - What are adverse effects of genetic testing? … family history–based testing. … testing. … BRCA1 gene testing. … Approaches
BRCA1/2 mutation testing
1 RCT (n = 1034)
Universal testing of Ashkenazi Jews
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www.uspreventiveservicestaskforce.org/uspstf/document/exercise-tolerance-testing-to-screen-for-coronary-heart-dise/coronary-heart-disease-electrocardiography-screening-2004
February 03, 2004 - book=es22 . 5 This article describes the findings on exercise tolerance testing only. … Exercise Tolerance Testing Before Beginning an Exercise Program
Exercise tolerance testing is frequently … The role of exercise testing in screening for coronary artery disease. … Prognostic value of exercise EKG testing in asymptomatic normotensive subjects. … Exercise testing in clinical medicine. Lancet 2000;356:1592-7.
80.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/RGu5KsFRY2YEAsDC9EQox9
December 31, 2013 - Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer in Women: Clinical Summary … of USPSTF Recommendation
RISK ASSESSMENT, GENETIC COUNSELING, AND GENETIC TESTING FOR BRCA-RELATED … positive screening results should receive genetic
counseling and, if indicated after counseling, BRCA testing … Grade: B
Do not routinely recommend genetic counseling or BRCA
testing to women whose family history … Screening Tests
Genetic risk assessment and BRCA mutation testing are generally multistep processes
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www.uspreventiveservicestaskforce.org/uspstf/announcements/final-recommendation-statement-risk-assessment-genetic-counseling-and-genetic-testing-brca12-related-cancer
August 20, 2019 - Final Recommendation Statement: Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA1/2- … released today a final recommendation statement on risk assessment, genetic counseling, and genetic testing … The Task Force found that some women may benefit from risk assessment, counseling, and testing for the
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www.uspreventiveservicestaskforce.org/uspstf/announcements/public-comment-draft-recommendation-statement-and-draft-evidence-review-risk-assessment-genetic-counseling-and-genetic-testing-brca
March 18, 2019 - Recommendation Statement and Draft Evidence Review: Risk Assessment, Genetic Counseling, and Genetic Testing … recommendation statement and draft evidence review on risk assessment, genetic counseling, and genetic testing … The Task Force found that testing is beneficial for the small number of women in the United States who
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing-2013
December 24, 2013 - Update in Progress for BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing … It is essential that before testing, the individual is fully informed about the implications of testing … The consequences of genetic testing for individuals and their relatives require more study. … Genetic testing may identify such mutations. … Although the preferred BRCA testing strategy is initial testing of a family member with breast or ovarian
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www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/file/supporting_documents/brca-medications-draft-rec-statement-bulletin.pdf
March 18, 2019 - Task Force Issues Draft Recommendation Statement on Risk Assessment, Genetic Counseling, and Genetic Testing … for BRCA-Related Cancer
Testing offers the opportunity to reduce certain types of cancer in women … “BRCA testing is beneficial for the small number of women in the United States who are at increased … “The test results are complex and testing comes with some harms, so we recommend women who get
tested … Screening ultimately helps determine if genetic counseling and testing
are needed.
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www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/file/supporting_documents/brcatestbulletin.pdf
December 24, 2013 - Preventive Services Task Force Finds Benefit in Risk Assessment, Genetic Counseling, and Genetic Testing … Preventive Services Task Force Finds Benefit in Risk
Assessment, Genetic Counseling, and Genetic Testing … for BRCA-
Related Cancer for Small Group of High-Risk Women
Task Force Finds Testing Harmful for Women … There are some harms of testing; results are often inconclusive and
many women could be burdened with … Therefore, the Task Force continues to recommend against routine genetic
counseling and BRCA testing
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer--brca-testing-ovarian-cancer-screeni
September 15, 2005 - archived
Final Recommendation Statement
Breast and Ovarian Cancer: BRCA Genetic Testing … against routine referral for genetic counseling or routine breast cancer susceptibility gene (BRCA) testing … Expand All
Preface
Genetic Risk Assessment and BRCA Mutation Testing for Breast and … The impact of BRCA testing on ethical, legal, and social issues needs to be better clarified. … Risk factor analysis and implications for genetic testing. JAMA 1997;278:1242-50.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/pACFPdCoN8fVoddBs-_CLE
November 12, 2019 - and harms of genetic testing, in-
terpretation of results after testing, and discussion of manage-
ment … Genetic Testing
Testing for BRCA1/2 mutations should be performed only when an
individual has personal … and harms of genetic testing, interpretation of results after testing, and discussion of management … c If testing for BRCA2.
d If testing for BRCA1. … gene testing.