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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/reliability-testing-grading-evidence_research.pdf
    May 01, 2012 - non-randomized studies of interventions or exposures Methods Research Report Reliability Testing … v Reliability Testing of the AHRQ EPC Approach to Grading the Strength of Evidence in Comparative … We conducted inter-rater reliability testing using data obtained from two published CERs. … Methods We conducted the inter-rater reliability testing using data obtained from two published CERs … Table A summarizes inter-rater testing results. ES-3 Table A.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rti-item-bank-bias-precision_research.pdf
    September 01, 2011 - Phase 2 included face validity testing, cognitive testing, content validity testing, and interrater … reliability testing. … Content Validity Testing An important goal of content validity testing was to identify a core set of … cognitive testing, and 40 items following content validity testing which were used for interrater … reliability testing.
  3. effectivehealthcare.ahrq.gov/get-involved/nominated-topics/population-children-18-years-of-age-1-what-are-the-incidences-and-prevalences-of-non-inflammatory-pain-syndromes-eg-benign-hypermobility-syndrome-patellofemoral-stress-syndrome-fibromyalgia-and-growing-pain-in-children-and-ad
    January 30, 2009 - (e.g. radiologic studies, laboratory testing, etc) Treatment Psychological (anxiety) Does your … Testing which may or may not be relevant or appropriate for the clinical situation. … As a result of misunderstanding the sensitivity and specificity of autoantibody testing for specific … rheumatic diseases, physicians continue to use such testing indiscriminately. … The answer will help to inform clinical practice guidelines for autoantibody testing in children.
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-test_research-protocol.pdf
    October 14, 2011 - October 14, 2011 Evidence-based Practice Center Systematic Review Protocol Project Title: PCA3 Testing … These programs are based on the premise that PSA testing can lead to early detection of prostate cancer … However, testing total PSA levels to decide which patients should undergo a biopsy has been found to … by and used at a single laboratory testing site). … The Key Questions (KQs) present three proposed scenarios in which this testing may be used.
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-screening_disposition-comments.pdf
    February 01, 2012 - Comparative Effectiveness of Fecal DNA Testing in Screening for Colorectal Cancer in Average Risk Adults … Fecal DNA Testing in Screening for Colorectal Cancer in Average-Risk Adults. … or soon to be available testing. … or soon to be available testing. … As the authors note, the field of fecal DNA testing is rapidly evolving.
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-genetic_methods.pdf
    July 01, 2012 - in cases that involve testing for heritable conditions. … 3b: How well does CYP450 testing predict drug efficacy? … Rather, family history-based testing is the paradigm that is recommended to guide the use of BRCA testing … Task Force on Genetic Testing (NIH). … of confirmatory testing.
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/wireless-motility-capsule_executive.pdf
    May 01, 2013 - We sought to determine whether WMC testing is useful in conjunction with or instead of other testingtesting. … Is WMC equivalent to conventional testing? Is it superior? … The SOE was low regarding the effect of WMC testing on treatment decisions based on ROM testing. … ROM testing involves exposure to at least one x ray by definition.
  8. effectivehealthcare.ahrq.gov/products/plasma-cell-dyscrasias-sflc-assay/research
    August 23, 2012 - defined as serum and urine electrophoresis or immunofixation electrophoresis), compared with traditional testing … Three retrospective, fair-quality studies evaluated the SFLC assay as an adjunct to traditional testing … role of the SFLC assay as a better indicator for therapeutic decisionmaking compared with traditional testing … insufficient to suggest that the assay may increase sensitivity when used as an adjunct to traditional testing … Future research should focus on standardization of diagnostic testing and monitoring algorithms in prespecified
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-screening_executive.pdf
    February 01, 2012 - Acceptability of Testing. … (of a program of testing, and harms of testing due to diagnostic inaccuracies) and optimal intervals … roles of fecal DNA testing. … Also, our review did not include stool-based testing using RNA or other genetic/genomic based testing … fecal DNA testing.
  10. effectivehealthcare.ahrq.gov/get-involved/nominated-topics/does-the-use-of-cytochrome-p450-2c19-cyp2c19-testing-to-predict-response-to-clopidogrel-in-people-1-with-acute-coronary-syndrome-2-who-have-suffered-other-cardiovascular-disease-related-events-eg-ischemic-stroke-symptomatic-p
    August 04, 2010 - Does the use of Cytochrome P450 2C19 (CYP2C19) testing to predict response to clopidogrel in people: … undergoing percutaneous coronary intervention, lead to improvements in health outcomes compared to a no-testing … would like to see compared: Health outcomes following therapy guided by CYP2C19 pharmacogenetic testing … , to predict clopidogrel response, versus a no-testing strategy. … Organization Please tell us how you heard about the Effective Health Care Program Testing
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendix-table-B-1-observational-studies.xlsx
    March 20, 2021 - Database was linked to the HMC national PCR testing and COVID-19 hospitalization and severity database … All individuals for whom serological testing data was collected in Qatar Deceased persons tested for … Note: Symptomatic and asymptomatic PCR testing were widely available for employees, with data available … occurred at days 0 and 7; clearence testing was conducted day 28; then homes returned to "routine testing … followed by repeated weekly testing; non-residential students were subject to random surveillance testing
  12. effectivehealthcare.ahrq.gov/products/colon-cancer-gene-profiling/research-protocol
    March 13, 2012 - What are the potential benefits and harms of this testing compared to current practice? … Is GEP testing a replacement or add-on technology? … Are there additional specific features of this testing (technology) that need to be considered? … Question 4 What important issues are raised by using GEP testing for stage II colon cancer? … Genomic Testing: ACCE Model Process for Evaluating Genetic Tests.
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-261-postpartum-care-executive-summary.pdf
    June 01, 2023 - • Healthcare Delivery Strategies – Coordination and Management of Care o For screening/testing care … to oral glucose tolerance testing up to 1 year postpartum but not random glucose testing or hemoglobin … (Hb) A1c testing (moderate SoE). … For screening/testing care (3 studies of mail and/or telephone reminders), testing reminders were associated … testing or HbA1c testing (moderate SoE).
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-genetic.ppt
    June 01, 2012 - , versus hereditary genetic testing for mutations or genomic profiles, since acquired mutation testing … of confirmatory testing. … testing for the BRCA mutation. … testing. … of confirmatory testing.
  15. effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-genetic.ppt
    June 01, 2012 - , versus hereditary genetic testing for mutations or genomic profiles, since acquired mutation testing … of confirmatory testing. … testing for the BRCA mutation. … testing. … of confirmatory testing.
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-decision-models_methods.pdf
    July 01, 2012 - The links between testing, test results, and patient outcomes are typically complex: even when testing … In most cases of evaluating medical testing, some type of formal modeling will be useful. … Table 10–2 classifies the results of PET testing. Table 10–2. … Patients without suggestive clinical examination are not candidates for PET testing. … Additional patient outcomes and pathways in evaluations of testing.
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0095_04-10-2009.pdf
    January 01, 2009 - Noninvasive technologies for the diagnosis of CAD including echocardiography, MIBI-SPECT, pharmacologic testing … , stress testing, etc. … Noninvasive technologies for the diagnosis of CAD including echocardiography, MIBI SPECT, pharmacologic testing … , stress testing, etc. … Additionally, reduction in cost and unnecessary repeat testing.
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_research-protocol.pdf
    March 13, 2012 - (This report will tabulate a listing of publications that used GEP testing and included patients with … What are the potential benefits and harms of this testing compared to current practice? e. … Is GEP testing a replacement or add-on technology? f. … Question 4 What important issues are raised by using GEP testing for stage II colon cancer? … Genomic Testing: ACCE Model Process for Evaluating Genetic Tests.
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_executive.pdf
    August 01, 2012 - or IFE), compared with traditional testing alone, improve the diagnostic accuracy for PCDs (MGUS, … to traditional testing on diagnostic performance as insufficient. … SFLC Assay and Diagnostic Testing (KQ1) The addition of SFLC testing to traditional tests of electrophoresis … However, it was not possible to determine whether SFLC testing is superior to traditional 10 testing … Few studies were available for specific comparisons between SFLC testing and traditional testing; the
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0332_07-29-2010.pdf
    January 01, 2010 - Outcome(s): Intermediate outcomes – diagnostic accuracy for detection of tumor; adverse events of testing … active surveillance vs. active treatment) lead to improvements in health outcomes compared to a no-testing … What are the potential harms of testing or subsequent management options associated with use of the … Having a tool with enhanced diagnostic specificity that improves diagnostic testing may partially reduce … While there are currently several guidelines addressing total PSA testing and prostate cancer screening

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