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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis_research-protocol.pdf
    June 06, 2011 - with exercise ECG is the oldest and most commonly used form of stress testing. … diagnostic performance, ability to localize areas of ischemia, and the option of performing stress testing … .3 In summary, many factors affect the accuracy of diagnostic testing for CAD in women,3 including: … .4 After undergoing coronary angiography, some patients may be referred for noninvasive stress testing … ACC/AHA 2002 guideline update for exercise testing: summary article: a report of the American College
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_disposition-comments.pdf
    June 12, 2012 - Perhaps "NIT modality" or "testing modality" may better reflect what it is meant. … However it appears to involve statistical testing. … P-values arise from testing for presence of interactions. … Layered testing as a focus for future research must be emphasized along with appropriateness of testing … We agree and have already discussed layered testing in the Discussion section.
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-usability-testing.pdf
    November 01, 2018 - Development and Usability Testing of EPC Evidence Review Dissemination Summaries for Health Systems Decisionmakers … Methods Research Report Development and Usability Testing of EPC Evidence … Summaries for Health Systems Decisionmakers Methods Research Report Development and Usability Testing … Development and Usability Testing of EPC Evidence Review Dissemination Summaries for Health Systems … We modified the interview guide and format of the interview substantially following pilot testing, in
  4. effectivehealthcare.ahrq.gov/products/grades-predictive-values/abstract
  5. effectivehealthcare.ahrq.gov/products/cancer-end-of-life-quality-meaures/research
  6. effectivehealthcare.ahrq.gov/sites/default/files/Evidence%20Summary_1.pdf
    April 01, 2020 - However, such testing is time consuming and access is limited in some clinical settings. … the biomarker testing search covered from 2012 to March 2019. … No studies examined the accuracy of blood testing. … studies and few brain imaging or CSF testing studies reported on harms. … Studies should systematically collect data on potential harms of cognitive testing.
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_executive.pdf
    June 01, 2012 - In testing for a statistically significant difference between the diagnostic accuracy of testing modalities … In fact, multiple testing or layered-testing strategies are areas where significant research is needed … A comparison of a functional testing strategy to an anatomic testing strategy for patients with symptomatic … As stated previously, multiple testing or layered-testing strategies, plus the influence on risk- factor … More evidence about predictors affecting diagnostic cardiac testing is needed to support or dispel
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_technical-brief.pdf
    December 01, 2012 - What Important Issues are Raised by Using GEP Testing for Stage II Colon Cancer? … What Important Issues are Raised by Using GEP Testing for Stage II Colon Cancer? … • Is GEP testing a replacement or add-on technology? Guiding Question 2. … Is GEP Testing a Replacement or add-on Technology? … Adverse events of testing?
  9. effectivehealthcare.ahrq.gov/sites/default/files/12_pregnancy_potential_high_impact_june_2012.pdf
    January 01, 2012 - Such testing is intended to help women avoid unnecessary, invasive followup testing that could pose …  Key Expert Comments: Overall, experts commenting on maternal blood-based fetal DNA testing viewed … However, a negative result could help some women avoid more invasive testing. … , this fetal DNA testing platform will likely not reduce health disparities. … Overall, experts saw potential for this intervention to significantly impact testing for trisomy 21 at
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-generated-health-data-protocol-chronic-conditions.pdf
    March 17, 2020 - Manufacturers of FDA regulated devices typically are required to demonstrate, through testing, that … If there are no such technologies, then we will expand this testing to include any technologies that … Data Synthesis Direct (hands on) usability and performance testing will be restricted to those … If there are no such technologies, then we will expand this testing to include any technologies … The team realized that the original proposed approach to direct usability and performance testing
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence-quiz.ppt
    May 29, 2025 - Case reports are hypothesis generating rather than hypothesis testing. … Cohort and case-control studies are well suited for testing hypotheses of whether one intervention is … Cohort and case-control studies are well suited for testing hypotheses that one intervention is associated
  12. effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence-quiz.ppt
    May 29, 2025 - Case reports are hypothesis generating rather than hypothesis testing. … Cohort and case-control studies are well suited for testing hypotheses of whether one intervention is … Cohort and case-control studies are well suited for testing hypotheses that one intervention is associated
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-applicability.ppt
    June 01, 2012 - Preventive lipid testing in individuals with cardiovascular disease has changed the proportion able to … to treatment, and variable ordering of testing across subjects. … Resources for conventional Pap smear testing were strained at the time, which contributed to the rise … The underlying incidence and prevalence data included: Provided context Informed modeling of testing … impact Reviewers could not estimate the usefulness of human papilloma virus testing among older women
  14. effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-applicability.ppt
    June 01, 2012 - Preventive lipid testing in individuals with cardiovascular disease has changed the proportion able to … to treatment, and variable ordering of testing across subjects. … Resources for conventional Pap smear testing were strained at the time, which contributed to the rise … The underlying incidence and prevalence data included: Provided context Informed modeling of testing … impact Reviewers could not estimate the usefulness of human papilloma virus testing among older women
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-2-risk-of-reinfection-from-SARSCoV2_0.pdf
    December 31, 2022 - antibody levels, SARS-CoV-2 variants, or case identification method (e.g., surveillance, symptomatic testing … Antibody testing has been proposed as a potential marker or correlate of protection against infection … In these situations, the prognostic value of antibody testing was identical to the prognostic value … settings when the timing of testing in relation to infection is unknown. … Re- infection with SARS-CoV-2 in Patients Undergoing Serial Laboratory Testing.
  16. effectivehealthcare.ahrq.gov/products/prostate-cancer-test/research
  17. effectivehealthcare.ahrq.gov/products/prostate-cancer-test/research-protocol
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-executive-summary.pdf
    May 01, 2025 - tests from labs that meet Centers for Medicare & Medicaid Services requirements for high-complexity testing … cer-methods-guide/overview 3 KQ 5: What are the harms of the evaluation and additional testing … -26 One of these studies also reported on possible harms of screening (KQ 4) and harms of followup testing … .31,32 If MCSTs prove effective and have few to no harms, people will need timely access to followup testing … Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention.
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/benefits-harms-modeling_research.pdf
    November 19, 2009 - This indirectness in the link between testing and its downstream effects poses practical challenges … Although testing in itself can affect outcomes directly,1 most of its impact is indirect. … Tradeoffs All testing procedures and treatment decisions are associated with benefits, risks, and … Direct effects include testing-induced emotional, cognitive, and behavioral changes or complications … Patient outcome after testing. Med Decis Making 2009;29(5):E30-E38 2.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-kidney-disease-anemia-2011_disposition-comments.pdf
    January 01, 2011 - However, considerable heterogeneity is likely to exist between testing platforms/methods, especially … We agree that considerable heterogeneity likely exists between testing platforms, and thus have added … The bundling of dialysis reimbursement has caused most providers to curtail lab testing, which may … Testing needs are different when clinical question is too much versus too little iron. … Testing needs are different when clinical question is too much vs. too little iron.

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