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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-test_research-protocol.pdf
    October 14, 2011 - October 14, 2011 Evidence-based Practice Center Systematic Review Protocol Project Title: PCA3 Testing … These programs are based on the premise that PSA testing can lead to early detection of prostate cancer … However, testing total PSA levels to decide which patients should undergo a biopsy has been found to … by and used at a single laboratory testing site). … The Key Questions (KQs) present three proposed scenarios in which this testing may be used.
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-genetic.ppt
    June 01, 2012 - , versus hereditary genetic testing for mutations or genomic profiles, since acquired mutation testing … of confirmatory testing. … testing for the BRCA mutation. … testing. … of confirmatory testing.
  3. effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-genetic.ppt
    June 01, 2012 - , versus hereditary genetic testing for mutations or genomic profiles, since acquired mutation testing … of confirmatory testing. … testing for the BRCA mutation. … testing. … of confirmatory testing.
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-decision-models_methods.pdf
    July 01, 2012 - The links between testing, test results, and patient outcomes are typically complex: even when testing … In most cases of evaluating medical testing, some type of formal modeling will be useful. … Table 10–2 classifies the results of PET testing. Table 10–2. … Patients without suggestive clinical examination are not candidates for PET testing. … Additional patient outcomes and pathways in evaluations of testing.
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_research-protocol.pdf
    March 13, 2012 - (This report will tabulate a listing of publications that used GEP testing and included patients with … What are the potential benefits and harms of this testing compared to current practice? e. … Is GEP testing a replacement or add-on technology? f. … Question 4 What important issues are raised by using GEP testing for stage II colon cancer? … Genomic Testing: ACCE Model Process for Evaluating Genetic Tests.
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-testing-machine-learning-tool-chronic-pain.pdf
    November 01, 2020 - Methods Research Report: Testing a Machine Learning Tool for Facilitating Living Systematic Reviews of … Chronic Pain Treatments Methods Research Report Testing a Machine Learning … Systematic Reviews of Chronic Pain Treatments Methods Research Report TestingTesting a Machine Learning Tool for Facilitating Living Systematic Reviews of Chronic Pain Treatments … Standard (MeSH and text word) search strategy testing ...............................................
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_executive.pdf
    August 01, 2012 - or IFE), compared with traditional testing alone, improve the diagnostic accuracy for PCDs (MGUS, … to traditional testing on diagnostic performance as insufficient. … SFLC Assay and Diagnostic Testing (KQ1) The addition of SFLC testing to traditional tests of electrophoresis … However, it was not possible to determine whether SFLC testing is superior to traditional 10 testing … Few studies were available for specific comparisons between SFLC testing and traditional testing; the
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0095_04-10-2009.pdf
    January 01, 2009 - Noninvasive technologies for the diagnosis of CAD including echocardiography, MIBI-SPECT, pharmacologic testing … , stress testing, etc. … Noninvasive technologies for the diagnosis of CAD including echocardiography, MIBI SPECT, pharmacologic testing … , stress testing, etc. … Additionally, reduction in cost and unnecessary repeat testing.
  9. Prognostic Tests (ppt file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-prognostic.ppt
    June 01, 2012 - Setting Who will use the prognostic test; how the test will be used; what the applicable testing scenario … Cost-effectiveness: Do the improvements in patient outcomes justify the additional costs of testing and … Were the subjects somehow referred or selected for testing? What was the testing scenario? … The second question asks about the subject selection and testing scenario. … Subpart A asks about uniformity of testing across all sites or all studies being reported.
  10. Prognostic Tests (ppt file)

    effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-prognostic.ppt
    June 01, 2012 - Setting Who will use the prognostic test; how the test will be used; what the applicable testing scenario … Cost-effectiveness: Do the improvements in patient outcomes justify the additional costs of testing and … Were the subjects somehow referred or selected for testing? What was the testing scenario? … The second question asks about the subject selection and testing scenario. … Subpart A asks about uniformity of testing across all sites or all studies being reported.
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/wireless-motility-capsule_disposition-comments.pdf
    May 20, 2013 - Our decision to exclude breath testing was confirmed with the Key Informants. … WMC testing resulted in changes in management in 84% of patients. … as surrogates for motility testing or to exclude alarm conditions. … The Use of Colonic Testing to Guide Treatment in the Introduction chapter now states, “If testing confirms … “established” standards of upper and lower gut motility testing.
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0332_07-29-2010.pdf
    January 01, 2010 - Outcome(s): Intermediate outcomes – diagnostic accuracy for detection of tumor; adverse events of testing … active surveillance vs. active treatment) lead to improvements in health outcomes compared to a no-testing … What are the potential harms of testing or subsequent management options associated with use of the … Having a tool with enhanced diagnostic specificity that improves diagnostic testing may partially reduce … While there are currently several guidelines addressing total PSA testing and prostate cancer screening
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis-future_research_1.pdf
    February 01, 2013 - or layered-testing strategies)? … layered-testing strategies? … or layered-testing strategies)? … or layered-testing strategies? … multiple testing or layered-testing strategies?
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/making-healthcare-safer-IV.pdf
    August 04, 2023 - Additionally, owing to the overlapping findings of the C.difficile testing chapter in MHS III, our … rapid response will also subsume the C.difficile surveillance and testing topics as it relates to active … surveillance, along with screening and testing in asymptomatic patients. … in 2017, there has been an acceleration in publications evaluating C.difficile testing and diagnostic … of surveillance cannot be evaluated • Testing stewardship interventions • No microbial organism
  15. Decision Modeling (ppt file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-decision-modeling.ppt
    June 01, 2012 - Links between testing, test results, and patient outcomes are complex. … Example: HIV testing Direct effects: Emotional distress from the testing process, cognitive/emotional … For example, testing for HIV has both direct and indirect effects. … summary testing performance (e.g., sensitivity, specificity). … The table shown classifies the results of PET testing.
  16. Decision Modeling (ppt file)

    effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-decision-modeling.ppt
    June 01, 2012 - Links between testing, test results, and patient outcomes are complex. … Example: HIV testing Direct effects: Emotional distress from the testing process, cognitive/emotional … For example, testing for HIV has both direct and indirect effects. … summary testing performance (e.g., sensitivity, specificity). … The table shown classifies the results of PET testing.
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/wireless-motility-capsule-future_research.pdf
    May 01, 2013 - We found two studies evaluating WMC as an add-on to other testing. … Consensus guidelines suggest that WMC testing is a replacement for current testing methods, however … The next series of questions asked about the incremental value of WMC testing in addition to other testingtesting. … We found two studies evaluating WMC as an add-on to other testing.
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_executive.pdf
    September 01, 2013 - Genetic testing for CYP2C19 ii. … Genetic testing for CYP2C19 followed by phenotypic testing for platelet reactivity iii. … Phenotypic testing for platelet reactivity iv. No testing b. … Use of phenotypic testing (but not genetic testing) as a monitoring test can be considered a variation … Combined Testing for CYP2C19 Variants and Phenotypic Testing To Guide Antiplatelet Treatment Of the
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_executive.pdf
    January 01, 2016 - Rapid Streptococcus Antigen Testing. … C-Reactive Protein Testing. … The combination of communication training and CRP testing was not different from CRP testing alone … + Procalcitonin testing + Rapid strep testing + Combination of patient and provider education plus audit … training, communication training plus CRP testing).
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-tests-proposals_research.pdf
    January 01, 2009 - Premature dissemination of testing technologies can lead to erroneous diagnoses and preventable delays … The ultimate question in decisions about testing is how much net gain from testing there will be for … The benefits from testing may be limited to a subset of those tested, so sample size requirements can … be substantial.45 Trials of testing need a well-defined protocol that links testing, results, and downstream … All of these practical problems are challenging but not insurmountable, and trials of testing can be

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