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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-protocol.pdf
June 05, 2024 - intervals, diagnostic pathways after a positive test, and equitable access related to screening,
followup testing … organizations such as guideline developers, and payers who determine coverage related to laboratory
testing … KQ 5: What are the harms of the evaluation and additional testing following a positive MCST or with … stool-based tests (colorectal), low-dose
computed tomography (lung), cytology, human papilloma
virus testing … Text
Adverse events from
diagnostic testing after a
positive screening
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effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-are-the-comparative-diagnostic-accuracy-diagnostic-thinking-therapeutic-and-patient-outcome-efficacy-of-non-invasive-tests-for-the-risk-stratification-of-patients-with-coronary-artery-disease
February 27, 2012 - combinations of stress and measure of induced ischemia, there are a number of options available for stress testing … Health Care Program
Involvement in the Evidence-based Practice Center Program
Noninvasive Testing
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effectivehealthcare.ahrq.gov/products/mrsa-screening-2010/research-protocol
June 02, 2011 - One key issue relates to the microbiological testing method applied. … The systematic review, however, will distinguish among screening that uses a testing modality with a … Interventions
A MRSA-screening strategy:
That includes: MRSA screening using a testing modality ( … 1 to 2 days after testing is performed); or
MRSA screening using a testing modality (typically, culture … ) with a longer turnaround time (results available >2 days after testing is performed);
And that
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/mrsa-screening-2010_research-protocol.pdf
January 01, 2010 - One key issue relates to the microbiological testing method applied. … The systematic
review, however, will distinguish among screening that uses a testing modality with … (results available on the same day as the testing is performed);
or
(2). … after testing is performed);
or
(3). … available >2 days after testing is performed);
b.
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effectivehealthcare.ahrq.gov/products/appendicitis/research-protocol
December 10, 2013 - on clinical grounds surgical consultation should be sought without delay for additional diagnostic testing … For the populations listed under Key Question 1a, what is the effect of alternative testing strategies … What factors modify the comparative effectiveness of testing for patients with RLQ pain and suspected … Studies meeting these criteria will be included regardless of the specific role of testing evaluated … Randomized controlled trials of alternative testing strategies including at least 10 patients per arm
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guide-editorial_methods.pdf
July 01, 2012 - compared to a reference standard, in this case, invasive
angiography) and the downstream result of testing
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-kidney-disease-anemia-2011_executive.pdf
January 01, 2011 - What are the adverse effects or harms associated with
testing using newer and/or older markers of iron … Studies did not attribute these deaths to either
testing or treatment. … What are the adverse
effects or harms
associated with
testing using newer
and/or older markers
of … Studies did not attribute these deaths to either
testing or any treatment. … A randomized trial of iron
deficiency testing strategies in hemodialysis patients.
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effectivehealthcare.ahrq.gov/sites/default/files/estimation-and-reporting_chapter-3.pptx
January 01, 2013 - achieve Possible Difficult to characterize sampling properties (e.g., confidence intervals)
Power of testing … relating to subgroup effects, and a detailed description of the statistical analytical plan on how testing … Evaluate chance findings by testing for interaction.
Avoid bias by adhering to sound study design. … To do this, chance findings should be evaluated by testing for interaction; biases should be avoided … significance If confirmatory analyses, do power calculations
Describe methods to adjust for multiple testing
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-function_executive.pdf
August 01, 2014 - Clinically, the most important use of
troponin testing is to identify patients
suspected of having … If the patient presents late
in the course of ACS, testing could take place during
the “plateau phase … Previous reviews and meta-analyses have investigated the
prognostic performance of troponin testing … 1.5 Among studies that directly compared troponin
testing in patients with CKD versus patients
with … Should cardiac troponin testing include other diagnostic
tests, such as stress testing or echocardiography
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effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
January 01, 2012 - Therefore, in many clinical
circumstances, “no treatment” or “no testing” may
not meet usual standards … Comparison with alternative treatment or testing
within the same or similar indication is usually a … However,
when different treatments or testing modalities are
recommended for patients with varying … The standard care could be no treatment
or no testing, a single treatment or testing, or a set
of existing … treatment or testing modalities.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-meta-analysis.ppt
June 01, 2012 - D-dimer testing and acute venous thromboembolism. A shortcut to accurate diagnosis? … D-dimer testing and acute venous thromboembolism. A shortcut to accurate diagnosis? … D-dimer testing and acute venous thromboembolism. A shortcut to accurate diagnosis? … Formal testing for heterogeneity confirmed this finding. … D-dimer testing and acute venous thromboembolism. A shortcut to accurate diagnosis?
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effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-meta-analysis.ppt
June 01, 2012 - D-dimer testing and acute venous thromboembolism. A shortcut to accurate diagnosis? … D-dimer testing and acute venous thromboembolism. A shortcut to accurate diagnosis? … D-dimer testing and acute venous thromboembolism. A shortcut to accurate diagnosis? … Formal testing for heterogeneity confirmed this finding. … D-dimer testing and acute venous thromboembolism. A shortcut to accurate diagnosis?
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effectivehealthcare.ahrq.gov/products/appendicitis/research
December 14, 2015 - and integrated diagnostic algorithms; to identify potential modifiers; and to evaluate the impact of testing
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-strength-evidence.ppt
June 01, 2012 - Another task in the first step is to choose the important outcomes that result from the testing encounter … Outcomes of Genetic Testing in Adults With a History of Venous Thromboembolism. … versus not testing is a tossup. … A simple decision model can be used to identify a threshold for which testing versus not testing is a … Outcomes of Genetic Testing in Adults With a History of Venous Thromboembolism.
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effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-strength-evidence.ppt
June 01, 2012 - Another task in the first step is to choose the important outcomes that result from the testing encounter … Outcomes of Genetic Testing in Adults With a History of Venous Thromboembolism. … versus not testing is a tossup. … A simple decision model can be used to identify a threshold for which testing versus not testing is a … Outcomes of Genetic Testing in Adults With a History of Venous Thromboembolism.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-abnormalities-tests-update_research-protocol.pdf
July 01, 2010 - Positive predictive value: the probability of a woman actually having breast
cancer after testing positive … Negative predictive value: the probability of a woman actually not having breast
cancer after testing
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0651-131114.pdf
June 20, 2013 - Strategies include testing (e.g., imaging tests),
decision tools, identifying risk factors for chronicity … Patients with low back pain
Intervention(s): Procedures to diagnose and treat low back pain, including: testing
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/mental-health-app-draft-technical-brief.pdf
June 21, 2021 - Iterative testing and refinement of the framework was done in five successive
rounds through double … Future
application, testing and refinements may be required to determine the framework’s suitability … We conducted five
rounds of testing and revised the framework. … Operationalizing this question proved to be inconsistent during the pilot testing. … Made to the Framework During Pilot Testing Rounds
Summary and Implications
Next Steps
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effectivehealthcare.ahrq.gov/products/hypothyroidism-hyperthyroidism-screening-treatment/research-protocol
March 10, 2010 - Screening for both subclinical hypo- and hyperthyroidism is accomplished through serum TSH, with testing … of serum free T4 and free T3 if the TSH falls outside of the normal range. 1 Additional testing is … predicated on the results of this testing for diagnostic purposes and exclusion of other conditions. … Interventions
Screening interventions: Serum TSH, with testing of serum free T4 and/or T3 if TSH is … , additional testing for thyroid antibodies, etc).
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effectivehealthcare.ahrq.gov/products/musculoskeletal-disorders-imaging/research-protocol
August 05, 2010 - What are the postulated advantages and disadvantages of positional MRI testing compared to contemporary … Guiding question 2:
What is the current availability and cost of positional MRI testing and what are … Approximately how many facilities and of what kind are currently providing positional MRI testing in … used
Study design and size
Role of the test in patient management
Setting where positional MRI testing … Moreover, we will record the outcomes being assessed in each study, including testing related harms,