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  1. effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-intro.ppt
    June 01, 2012 - A causal chain diagram can be used to illustrate the steps from the testing phase to the point that a
  2. Santa_ECCS2012 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/santa_eccs2012.pdf
    February 01, 2013 -   • A first round of field testing was conducted with 83 primary care physicians and a second round … of field testing  with an additional  172 physicians.
  3. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - at Cambridge University in the United Kingdom who evaluated the device estimated that Cytosponge testing … Cytosponge testing could be used in place of routine endoscopy for identifying and monitoring Barrett … of patients at increased risk of having Barrett’s esophagus, rather than true screening (universal testing … .”27 Acceptance and adoption: All experts anticipated moderate to wide acceptance of Cytosponge testing … There are some [minor] storage issues, training, result tracking, and facility issues…[Cytosponge testing
  4. effectivehealthcare.ahrq.gov/sites/default/files/celiac-disease_executive.pdf
    January 01, 2016 - Length of time ingesting gluten before diagnostic testing? Key Question 3. … Patients previously testing negative for CD? Key Question 4. … Testing for tTG IgA has a high PPV for most clinical populations with a modest prevalence of CD. … Thus, no clinical implications for testing individuals with specific risks can be stated at this time … A combination of positive serological testing with a threshold level at or several times above the
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_surveillance.pdf
    January 01, 2013 - Participants completed Humphrey Visual Field testing in addition to FDT C-20-1, GAT, and central corneal … The HFA Short Wavelength Automated Perimetry testing protocol (the most frequently reported) included … of optic nerve damage (e.g., HRT, OCT, and cup/disc ratio), organized in a community setting with testing … Participants completed Humphrey Visual Field testing in addition to FDT C-20-1, GAT, and central corneal … The HFA Short Wavelength Automated Perimetry testing protocol (the most frequently reported) included
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
    September 01, 2014 - relevant results, factors were coded inconsistently and details that would allow formal statistical testing … the test performance meta- analyses presented in the preceding sections we evaluated the impact of testing … delayed diagnosis on the basis of biopsy results is the most important (adverse) outcome related to testing … Outcomes of testing in a hypothetical cohort of 1,000 women Lines correspond to different test modalities
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-pancreas_research-protocol.pdf
    August 09, 2013 - factors (e.g., Peutz-Jeghers syndrome, Lynch syndrome, and BRCA2, PALB2, and p16 mutations) motivate testingTesting for recurrent pancreatic cancer is excluded. 4. … exp diagnostic errors/ or exp diagnostic error/) 34 Pancreatic cancer and imaging and diagnostic testing
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendicitis_disposition-comments.pdf
    December 14, 2015 - available to clinicians and there is a great need for evidence to inform us about the impact of testing … The authors make a somewhat sweeping statement regarding the relationship of diagnostic testing to … mention that a large percentage of patients present atypically, so clinicians rely on the use of testing … This is the key idea behind repeat testing with deferred treatment, an issue that is now discussed … I am concerned that this study may lead to even higher reliance on radiologic testing that is clearly
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_executive.pdf
    April 01, 2012 - field loss may be impractical for population-based screening due to the length of time required for testing … included studies of suspected OAG subpopulations, which included participants identified from prior testing … conducted alone or in any possible combination (including multicomponent simultaneous or sequential testing … screening tests performed alone or in combination.81 Participants completed Humphrey Visual Field testing … Combining structural and functional testing for detection of glaucoma.
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_disposition-comments.pdf
    February 13, 2012 - adding layers of additional tests to improve specificity will result in use of even further additional testing … It would be much more pertinent to focus this analysis by problem rather than grouping all testing … what is meant by “aggressive diagnostic testing”? This seems very opinionated. … We have modified the text to remove the phrase “aggressive diagnostic testing.” … Peer Reviewer #6 Discussion Unless non invasive testing can accurately determine a lesion to have
  11. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_executive.pdf
    December 01, 2011 - diagnostic tests depend on patient or specimen characteristics or the clinical scenarios that lead to testing … In some studies, a low rate of CDI precluded statistical testing. … The reviewed comparative studies did not clearly define the testing scenario including the setting, disease … Laboratory confirmation of a pathogenic C. difficile organism (e.g., by toxin testing) and clinical symptoms … Clostridium difficile testing in the clinical laboratory by use of multiple testing algorithms.
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_executive.pdf
    May 01, 2013 - Effect of Testing Variables (Timing, Frequency, Setting, Provider) on Screening Performance Two … used a range of cutoffs to signal probable postpartum depression (range: 8–13), and descriptions of testing … Our modeling suggests that serial testing using a highly sensitive test (such as the “two-question … The choice of optimal test and test thresholds, testing algorithms, and test frequency need to be made … screening outcomes resulting from other strategies designed to minimize false positives, such as serial testing
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0359_10-15-2010.pdf
    January 01, 2010 - sclerosis due to neurologic deficits of subacute onset Intervention(s): MRI, cerebrospinal fluid testing
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_disposition-comments.pdf
    September 23, 2014 - No other testing is therefore necessary in this group, and patients will typically undergo a ct guided … For each stage of care, appropriate testing and treatment are outlined. … This standard helps imaging facilities conduct quality testing and monitoring of X-ray equipment used
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-ambulatory-therapeutics_research.pdf
    July 01, 2009 - Given that DARTNet uses clinically derived data, it was important to perform detailed testing of all … Software functionality testing included evaluating overall system performance, characteristics of … Testing of the system security is designed to ensure that DARTNet does not represent a security threat … The general approach to validating these areas involved User Acceptance Testing. … In general, acceptance testing involves running a series of tests on a completed system.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
    September 01, 2014 - Clinical outcomes – Mortality – Quality of life • Adverse effects and harms – Procedural harms of testingTesting for recurrent pancreatic cancer was excluded. d.
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-risk-assessment-genes_executive.pdf
    July 01, 2012 - asymptomatic men).14 A meta- analysis of seven randomized controlled trials of screening using PSA testing … Companies known to offer testing for the risk of prostate cancer based on SNP panels were approached … in May of 2011, as were companies known to offer genetic testing more generally. … Risks and benefits of population-based genetic testing for Mendelian subsets of common diseases were … Improving the prediction of complex diseases by testing for multiple disease-susceptibility genes.
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay_research-protocol.pdf
    May 02, 2011 - gammopathy of undetermined significance, and amyloidosis  Less sensitive and more variable than SFLC testing … could differ depending on the PCD, and specific diseases, such as AL amyloidosis, still require urine testing … diagnosis of PCD (MM, NSMM, or AL amyloidosis) with and without measurable disease by traditional testing …  Comparators Traditional testing: o SPEP, UPEP, SIFE, and UIFE. … In general, the figure illustrates how serum-free light chain analysis versus traditional testing (serum
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0520-131115.pdf
    May 29, 2025 - Topic 0438 Risk stratification and CAD NSD FINAL_SJ-2 Risk stratification and CAD Nomination Summary Document Results of Topic Selection Process & Next Ste…
  20. Gout Executive-2016 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive-2016.pdf
    January 01, 2016 - analysis • Type of provider aspirating joint • Type of provider assessing fluid Diagnostic Testing … Key Question 2 assesses potential adverse effects that might be associated with testing: short- and … dotted lines indicate possible outcomes; for example, diagnostic accuracy and adverse effects of testing … they addressed Key Question 2 (adverse events or other negative outcomes in individuals undergoing testing … In addition, specific elements of the criteria, such as hyperuricemia, require additional testing.

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