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effectivehealthcare.ahrq.gov/products/reliability-testing-grading-evidence/research
May 22, 2012 - Reliability Testing of the AHRQ EPC Approach to Grading the Strength of Evidence in Comparative Effectiveness … Our project focused on inter-rater reliability testing of the two main components of the AHRQ approach … Data Sources and Methods
We conducted inter-rater reliability testing using data obtained from two
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effectivehealthcare.ahrq.gov/products/coronary-artery-disease-testing/research
March 29, 2016 - 2012 Topic Suggestion Jan. 15, 2015 Research Protocol Mar. 29, 2016 Systematic Review Noninvasive Testing … Revascularization referral was more common following CCTA versus functional testing in general (high … In ED settings, additional testing was more common following CCTA than following SPECT (high strength … or further testing was not described in RCTs. … regarding exposure for the initial test or downstream testing.
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effectivehealthcare.ahrq.gov/products/cancer-quality-indicator-testing/research
May 19, 2010 - Cancer Quality-ASSIST Supportive Oncology Quality Indicator Set: Feasibility, Reliability, and Validity Testing … had both reliability and validity issues, leaving a set of 41 indicators most promising for further testing … communication are very different from those assessing discrete, concrete events like fecal occult blood testing … Cancer Quality-ASSIST supportive oncology quality indicator set: feasibility, reliability, and validity testing
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effectivehealthcare.ahrq.gov/products/genetic-testing-developmental-disabilities/technical-brief
June 30, 2015 - Research Protocol Jun. 30, 2015 Technical Brief Nov. 3, 2015 Disposition of Comments Report Genetic Testing … We searched the National Center for Biotechnology Information's Genetic Testing Registry (GTR) to identify … Common genetic testing methods used include array comparative genomic hybridization, microarray, DNA … We did not identify any studies that directly assessed the impact of genetic testing on health outcomes
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effectivehealthcare.ahrq.gov/products/colorectal-cancer-screening/research
February 29, 2012 - Research Protocol Feb. 29, 2012 Systematic Review May. 17, 2012 Disposition of Comments Report Fecal DNA Testing … Structured Abstract
Objectives
To review the evidence on fecal DNA testing to screen for colorectal … We found no studies that specifically evaluated the harms of fecal DNA testing. … There is also insufficient evidence for the harms, analytic validity, and acceptability of testing in … Existing evidence has little or no applicability to currently available fecal DNA testing.
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effectivehealthcare.ahrq.gov/health-topics/end-life-issues
May 17, 2010 - Testing Cancer Quality Measures for End-of-Life Care
Research Report
Archived
May 17, … Cancer Quality-ASSIST Supportive Oncology Quality Indicator Set: Feasibility, Reliability, and Validity Testing
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effectivehealthcare.ahrq.gov/health-topics/health-facilities
November 15, 2011 - The AHRQ Evidence-Based Care (EBC) Challenge
Research Report
June 1, 2013
Testing … Aureus (MRSA)
Systematic Review
Archived
June 20, 2013
Routine Preoperative Testing … in Shared Decision Making (Session III)
White Paper
September 30, 2013
PCA3 Testing … Aggression in Dementia
Systematic Review
Archived
March 21, 2016
Noninvasive Testing … Coronary Artery Disease
Systematic Review
Archived
March 29, 2016
Noninvasive Testing
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effectivehealthcare.ahrq.gov/products/coronary-artery-disease-testing/research-protocol/
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effectivehealthcare.ahrq.gov/products/genetic-testing-developmental-disabilities/research-protocol/
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effectivehealthcare.ahrq.gov/products/dcis-prognostic-tests/research
September 13, 2012 - Rates of testing varied significantly across race groups for all tests. … Neither study included ER testing. … ER testing is considered standard of care for women with early invasive cancer. … Studies of PR testing are inconclusive in the context of DCIS. … and to better understand how testing rates differ between both groups.
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effectivehealthcare.ahrq.gov/get-involved/nominated-topics/key-questions-1-does-routine-preoperative-testing-compared-to-no-testing-or-alternative-testing-strategies-improve-outcomes-such-as-surgical-complications-other-morbidity-and-mortality-among-patients-undergoing-elective-surg
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/dcis-prognostic-tests_research.pdf
August 22, 2012 - Estrogen and Progesterone Receptor Testing
Rates of ER/PR testing for women with DCIS varied
strongly … HER2 Testing
As with ER/PR testing, HER2 testing increased dramati-
cally among women with DCIS between … BRCA Testing
We found a low rate (0.6%) of BRCA testing among
women with DCIS. … and are thus testing randomly. … Data Points • # 15 • Breast Cancer Diagnostic Workup
14
Appendix D: ER/PR testing and HER2 testing
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effectivehealthcare.ahrq.gov/health-topics/health-occupations
January 17, 2012 - Implants for Aortic Valve Disease
Research Report
March 28, 2013
Reliability Testing … Osteoarthritis: Future Research Needs
Systematic Review
Archived
February 1, 2013
PCA3 Testing … Global Health Evidence Evaluation Framework
White Paper
June 24, 2013
Genetic Testing … Cancer Quality-ASSIST Supportive Oncology Quality Indicator Set: Feasibility, Reliability, and Validity Testing … September 30, 2012
Additional Patient Outcomes and Alternative Pathways in Evaluations of Testing
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0594-131115.pdf
March 13, 2013 - Topic 0505 Genetic Testing for Developmental Diseases NSD FINAL_SJ … § Genetic Testing for Developmental Diseases
Nomination Summary Document … Results of Topic Selection Process & Next Steps
The topic, Genetic Testing … Comparator(s): Other genetic testing/no genetic testing
Outcome(s): Changes to child treatment specific … Given the limited available evidence, the rapid pace of change in genetic testing, and the recent
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/outcomes-testing-evaluation_research.pdf
January 01, 2009 - Some effects from testing are direct. … A study of genetic testing for BRCA1 and BRCA2
found that women testing positive for a mutation reported … Behavioral Effects of Testing
The emotional, social, and cognitive effects of testing may also affect … In this, testing is no exception. … Most of these frameworks
look at determinants of testing, however, not at the effects of testing.
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effectivehealthcare.ahrq.gov/products/antiplatelet-treatment/research
September 25, 2013 - 2011 Research Protocol Sep. 25, 2013 Systematic Review Feb. 13, 2014 Disposition of Comments Report Testing … for CYP2C19 variants and phenotypic testing to measure platelet reactivity) to identify patients who … (for CYP2C19 variants) or phenotypic testing (for platelet reactivity). … One hundred six studies provided information on the ability of genetic testing for CYP2C19 variants to … treatment choice: 1 randomized trial of testing versus no testing, 12 randomized treatment trials assessing
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effectivehealthcare.ahrq.gov/sites/default/files/coronary-artery-disease-testing_executive.pdf
March 01, 2011 - Additional Noninvasive Testing
Additional noninvasive testing, which impacts the cost and
efficiency … Harms and Consequences of Testing
Harms of testing were rarely reported and details on
comparisons of … No
studies that compared testing with an arm that received
no testing were identified, so the impact … Studies comparing testing
versus clinical evaluation without testing would provide
valuable information … for assessing the need for testing,
possible overuse of testing, and the impact of testing in
general
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/genetic-testing-developmental-disabilities_disposition-comments.pdf
June 30, 2015 - Testing in these two situations should be looked
at separately. … when
compared with no testing. … that no testing for
any underlying diagnosis is worthwhile. … They may do
focused/targeted aCGH/microarray testing. … Good example
of potential risk of testing?
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effectivehealthcare.ahrq.gov/get-involved/nominated-topics/for-women-when-comparing-noninvasive-testingwhich-testing-method-echocardiography-mibi-spect-pharmacological-testing-etc-is-more-accurate-in-diagnosing-coronary-artery-disease-there-has-been-inadequate-studies-done-on-women-
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effectivehealthcare.ahrq.gov/sites/default/files/whitepaper4-bossuyt02262010-2.pdf
January 01, 2009 - Some effects from testing are direct. … A study of genetic testing for BRCA1 and BRCA2
found that women testing positive for a mutation reported … Behavioral Effects of Testing
The emotional, social, and cognitive effects of testing may also affect … In this, testing is no exception. … Most of these frameworks
look at determinants of testing, however, not at the effects of testing.