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21. Methods Guide for Medical Test Reviews Chapter 3 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-outcomes_methods.pdf
    July 01, 2012 - Direct health effects of testing Emotional, cognitive, social, behavioral re- sponses to testing … Legal, ethical effects of testing Costs Outcome Origins From Testing Process From Test Results … Legal and ethical effect of testing. … Legal and ethical effects of testing. … Legal and ethical effects of testing.

22. Disposition of Comments Report for Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
    September 25, 2013 - for CYP2C19 variants and phenotypic testing for platelet reactivity, focusing on standardizing testing … This appears to be a very rigorous review of platelet function testing and CYP2C19 genetic testing for … We reviewed several studies comparing testing versus no-testing strategies for tests measuring platelet … Use of phenotypic testing (but not genetic testing) as a monitoring test can be considered a variation … Pharmacokinetic and pharmacodynamic testing (such as platelet function testing) in healthy volunteers

23. Noninvasive Testing for Coronary Artery Disease | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/coronary-artery-disease-testing/research-protocol

24. Genetic Testing for Developmental and Intellectual Disabilities | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/genetic-testing-developmental-disabilities/research-protocol

25. Topic 0451 Celiac Disease NSD FINAL (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-533_05-24-2013.pdf
    January 01, 2013 - Testing … The current strategy for diagnosing CD involves serial serologic and histopathologic testing. … After initial evaluation and testing for iron, folate and vitamin B12 deficiencies and ruling out other … Objective 4 - Expected consequences of testing for CD (Celiac 4) a. … What are the expected consequences of testing for CD in the following populations: i.

26. Disposition of Comments for CER 171 Noninvasive Testing for Coronary Artery Disease (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/coronary-artery-disease-testing_disposition-comments.pdf
    March 29, 2016 - Peer Reviewer 1 Methods However it would be helpful to include testing vs no testing in low risk groups … We identified no studies evaluating testing versus no testing that met our inclusion criteria. … testing as analyzed in this report. … There were no studies identified that evaluated testing versus no testing in the population of interest … No studies comparing testing vs. no testing were identified.

27. Considering the Range of Decision-Relevant Effects (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-choosing-outcomes.ppt
    June 01, 2012 - Determine the group to which the testing outcomes are most relevant. … consideration; and (5) the costs of testing. … Additional patient outcomes and pathways in evaluations of testing. … consideration; and (5) the costs of testing. … Genetic Testing Segal JB.

28. Considering the Range of Decision-Relevant Effects (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-choosing-outcomes.ppt
    June 01, 2012 - Determine the group to which the testing outcomes are most relevant. … consideration; and (5) the costs of testing. … Additional patient outcomes and pathways in evaluations of testing. … consideration; and (5) the costs of testing. … Genetic Testing Segal JB.

29. Antibiotics-Respiratory-Infection Clinician (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_clinician.pdf
    March 01, 2016 - While procalcitonin point-of-care testing reduced antibiotic prescribing in adults, use of an adult … Clinical Interventions (Point-of-Care Testing): ��Procalcitonin point-of-care testing in adults reduced … ��Streptococcal antigen point-of-care testing (rapid strep testing) reduced overall prescribing by 20 … ��Point-of-care testing for influenza in children had no effect on antibiotic prescribing (���). … strep testing 3 RCTs ��� Inappropriate prescribing -33% Greater reduction with rapid strep testing 1

30. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0068_01-30-2009.pdf
    January 01, 2009 - Results of Topic Selection Process & Next Steps  Antinuclear autoantibody and rheumatoid factor testing … is interested in the diagnostic accuracy of antinuclear antibody (ANA) and rheumatoid factor (RF) testing … clinical factors that may modify accuracy or benefits and harms associated with obtaining ANA and RF testing … not limited to):  Patient referrals (i.e., to pediatric rheumatologists)  Additional diagnostic testing … (e.g., radiologic studies, laboratory testing, etc

31. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-screening_research-protocol.pdf
    May 18, 2011 - Practice Center Systematic Review Protocol Project Title: Comparative Effectiveness of Fecal DNA Testing … (FOBT) or fecal immunohistochemical testing (FIT) annually; and flexible sigmoidoscopy every 5 years … . 3 Fecal DNA testing detects molecular alterations associated with CRC development in cellular … Question 6: Harms What are the potential harms of fecal DNA testing? … FOBT = Fecal Occult-Blood Testing USPSTF = U.S.

32. Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma Cell Dyscrasias: Future Research Needs (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay-future_research.pdf
    September 01, 2012 - Intervention SFLC testing and SFLC testing in combination with traditional testing. … SFLC testing and SFLC testing in combination with traditional testing. … Intervention SFLC testing, metrics of SFLC testing, frequency of SFLC testing. SFLC testing. … SFLC testing and SFLC testing in combination with traditional testing. … Intervention SFLC testing, metrics of SFLC testing, frequency of SFLC testing SFLC testing.

33. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/wireless-motility-capsule_research-protocol.pdf
    March 14, 2012 - Whether it can replace or should supersede other testing methods is controversial. … An advantage of colon scintigraphy is that testing can be completed in 1 to 2 days. … Capsule testing cannot be performed in any patient expected to have stricture or stenosis. … Other testing might be required to ensure that no narrowing is present. … , then the next step in evaluation is transit testing with use of laxatives.

34. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
    November 22, 2011 - the use of testing (e.g., genetic testing to determine CYP2C19 status or phenotypic testing of platelet … Genetic testing for CYP2C19 ii. … Genetic testing for CYP2C19 followed by phenotypic testing for platelet reactivity iii. … Phenotypic testing for platelet reactivity iv. No testing b. … Potential test-and-treat strategies will include testing for CYP2C19 genetic variants, testing for

35. Comparative Effectiveness of Fecal DNA Testing in Screening for Colorectal Cancer in Average Risk Adults. (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-screening_disposition-comments.pdf
    February 01, 2012 - Comparative Effectiveness of Fecal DNA Testing in Screening for Colorectal Cancer in Average Risk Adults … Fecal DNA Testing in Screening for Colorectal Cancer in Average-Risk Adults. … or soon to be available testing. … or soon to be available testing. … As the authors note, the field of fecal DNA testing is rapidly evolving.

36. Methods Guide for Medical Test Reviews Chapter 11 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-genetic_methods.pdf
    July 01, 2012 - in cases that involve testing for heritable conditions. … 3b: How well does CYP450 testing predict drug efficacy? … Rather, family history-based testing is the paradigm that is recommended to guide the use of BRCA testing … Task Force on Genetic Testing (NIH). … of confirmatory testing.

37. Appendix-Table-B-1-Observational-Studies (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendix-table-B-1-observational-studies.xlsx
    March 20, 2021 - Database was linked to the HMC national PCR testing and COVID-19 hospitalization and severity database … All individuals for whom serological testing data was collected in Qatar Deceased persons tested for … Note: Symptomatic and asymptomatic PCR testing were widely available for employees, with data available … occurred at days 0 and 7; clearence testing was conducted day 28; then homes returned to "routine testing … followed by repeated weekly testing; non-residential students were subject to random surveillance testing

38. Wireless-Motility-Capsule Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/wireless-motility-capsule_executive.pdf
    May 01, 2013 - We sought to determine whether WMC testing is useful in conjunction with or instead of other testing … testing. … Is WMC equivalent to conventional testing? Is it superior? … The SOE was low regarding the effect of WMC testing on treatment decisions based on ROM testing. … ROM testing involves exposure to at least one x ray by definition.

39. Colorectal-Cancer-Screening Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-screening_executive.pdf
    February 01, 2012 - Acceptability of Testing. … (of a program of testing, and harms of testing due to diagnostic inaccuracies) and optimal intervals … roles of fecal DNA testing. … Also, our review did not include stool-based testing using RNA or other genetic/genomic based testing … fecal DNA testing.

40. Executive Summary_Comparative Effectiveness Review No. 261_Postpartum Care up to 1 Year After Pregnancy: A Systematic Review and Meta-Analysis (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-261-postpartum-care-executive-summary.pdf
    June 01, 2023 - • Healthcare Delivery Strategies – Coordination and Management of Care o For screening/testing care … to oral glucose tolerance testing up to 1 year postpartum but not random glucose testing or hemoglobin … (Hb) A1c testing (moderate SoE). … For screening/testing care (3 studies of mail and/or telephone reminders), testing reminders were associated … testing or HbA1c testing (moderate SoE).