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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-prognostic_methods.pdf
    July 01, 2012 - what it measures, how it is done, how clinical specimens are obtained, processed, and stored for testing … What is the applicable testing scenario? … Cost effectiveness: Do the improvements in patient outcomes justify the additional costs of testing … Were the subjects somehow referred or selected for testing? What was the testing scenario? 3.
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-protocol.pdf
    June 05, 2024 - intervals, diagnostic pathways after a positive test, and equitable access related to screening, followup testing … organizations such as guideline developers, and payers who determine coverage related to laboratory testing … KQ 5: What are the harms of the evaluation and additional testing following a positive MCST or with … stool-based tests (colorectal), low-dose computed tomography (lung), cytology, human papilloma virus testing … Text Adverse events from diagnostic testing after a positive screening
  3. effectivehealthcare.ahrq.gov/sites/default/files/c-difficile-update_disposition-comments.pdf
    March 29, 2016 - section to avoid suggesting that this is the preferred method for testing. … For example- the last paragraph of the testing section is important. … The communication offered suggestions for guidance on donor selection and screening, serum testing, … and stool testing. … The sections on diagnostic testing and treatment are especially helpful in clarifying such decisions
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/aggression_executive.pdf
    October 01, 2016 - occurred in unit that received the staff training vs. the control unit (4 vs. 5); no statistical testing … restraint on the unit who received the training vs. the control unit (84 vs. 228), no statistical testing … in unit that received the staff training than in control unit (28.2% vs. +7.7%), no statistical testing … data for medication protocols; all reported small numbers of events and performed no statistical testing … flunitrazepam, no statistical testing reported (3 vs. 3, p=NR).48 Drug-related adverse events 91
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/diagnostic-tests-accuracy_research.pdf
    January 01, 2013 - algorithms in the frequentist and Bayesian settings, using approximate and discrete likelihoods to model testing … 1 Background The value of diagnostic testing for patient management ultimately derives from its effect … Testing primarily affects outcomes by indirect means, influencing downstream patient management decisions … , including decisions for further testing, and administration or choice of treatment. … screening programs do not rely on isolated markers, but combine sequential biochemical and ultrasound testing
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_surveillance.pdf
    April 01, 2012 - August 8, 2011 Surveillance Report: July, 2012 Key Findings: - The conclusions for KQ2 (phased testing … How does phased testing (screening tests or battery followed by full test) compare to full testing alone … testing when indicated, to diagnose sleep apnea, as only one study that met our inclusion criteria … This prospective quality C study did not fully analyze the phased testing, thus the sensitivity and … How does phased testing (screening tests or battery followed by full test) compare to full testing alone
  7. effectivehealthcare.ahrq.gov/products/study-design-classification/research
  8. effectivehealthcare.ahrq.gov/products/musculoskeletal-complaints-tests-children/research-protocol
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-selection-harms-systematic-reviews.pdf
    February 01, 2018 - diagnostic tests for Imprecision or insensitivity • Diagnostic tests (e.g. genetic or hematologic testing … ► Nonspecific diagnostic tests can lead to false positives that may precipitate further unneeded testing … or insensitivity For reviews that involve effects of diagnostic tests, be it genetic or hematologic testing … consider inclusion of over-diagnosis and overtreatment, as well as other harms related to diagnostic testing … the inclusion of intermediate measures of harm such as over-diagnosis or overtreatment as a result of testing
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cognitive-decline_research-protocol.pdf
    March 22, 2016 - Many studies testing the association of preventive factors or effectiveness of interventions for preventing … Oversimplification of the models testing intervention effectiveness is another challenge we identified … Research to date has examined fairly simple models testing intervention effects on populations with … For  KQ3:  Adults with  normal or abnormal cognition  who  have  had testing such   as  cognitive  tests … ,  blood/CSF  testing, or brain  imaging  used  in  intervention   studies in  KQ1  or  KQ2.
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
    December 01, 2012 - The purpose of hormonal stimulation testing for bilateral nonpalpable cryptorchidism is to determine … no imaging, hormonal stimulation testing or not) and intervention (surgical vs. hormonal, one-stage … In male children with bilateral nonpalpable testicles, does the use of hormonal stimulation testing … Utility of Hormone Stimulation Testing To Determine Course of Treatment Two studies of a total of … 44 boys examined the potential for hormonal stimulation testing to predict anorchia.
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hyperactivity-disorder-protocol-amendment.pdf
    January 08, 2025 - Adults with suspected ADHD Diagnostic Test Unintended consequences or adverse effects of testing … diagnostic) OR title: (diagnosed) OR title: (Measure) OR title: (test) OR title: (tests) OR title: (testing … abstract: (diagnosed) OR abstract: (Measure) OR abstract: (test) OR abstract: (tests) OR abstract: (testing … OR interview OR interviews OR diagnosis OR diagnostic OR diagnosed OR Measure OR test OR tests OR testing … OR interview OR interviews OR diagnosis OR diagnostic OR diagnosed OR Measure OR test OR tests OR testing
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hyperactivity-disorder-protocol.pdf
    November 10, 2024 - Likelihood ratios • False positives • False negatives Unintended consequences or adverse effects of testing … diagnostic) OR title: (diagnosed) OR title: (Measure) OR title: (test) OR title: (tests) OR title: (testing … abstract: (diagnosed) OR abstract: (Measure) OR abstract: (test) OR abstract: (tests) OR abstract: (testing … OR interview OR interviews OR diagnosis OR diagnostic OR diagnosed OR Measure OR test OR tests OR testing … OR interview OR interviews OR diagnosis OR diagnostic OR diagnosed OR Measure OR test OR tests OR testing
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer_research-protocol.pdf
    July 24, 2013 - Surveillance is the use of periodic testing to monitor lesions in the liver that give rise to a clinical … What are the adverse effects or harms associated with using imaging techniques related to testing or …  Psychosocial effects of diagnostic testing on patients, patients’ caregivers, and other family …  Psychosocial effects of diagnostic testing on patients, patients’ caregivers, and other family …  Psychosocial effects of diagnostic testing on patients, patients’ caregivers, and other family
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-meta-analysis.ppt
    June 01, 2012 - D-dimer testing and acute venous thromboembolism. A shortcut to accurate diagnosis? … D-dimer testing and acute venous thromboembolism. A shortcut to accurate diagnosis? … D-dimer testing and acute venous thromboembolism. A shortcut to accurate diagnosis? … Formal testing for heterogeneity confirmed this finding. … D-dimer testing and acute venous thromboembolism. A shortcut to accurate diagnosis?
  16. effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-meta-analysis.ppt
    June 01, 2012 - D-dimer testing and acute venous thromboembolism. A shortcut to accurate diagnosis? … D-dimer testing and acute venous thromboembolism. A shortcut to accurate diagnosis? … D-dimer testing and acute venous thromboembolism. A shortcut to accurate diagnosis? … Formal testing for heterogeneity confirmed this finding. … D-dimer testing and acute venous thromboembolism. A shortcut to accurate diagnosis?
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-performance_methods.pdf
    July 01, 2012 - screening performance of the test, it quantifies the impact of patient management strategies that include testing … PSA levels are not elevated in as many as 15 percent of individuals with prostate cancer, making PSA testing
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-strength-evidence.ppt
    June 01, 2012 - Another task in the first step is to choose the important outcomes that result from the testing encounter … Outcomes of Genetic Testing in Adults With a History of Venous Thromboembolism. … versus not testing is a tossup. … A simple decision model can be used to identify a threshold for which testing versus not testing is a … Outcomes of Genetic Testing in Adults With a History of Venous Thromboembolism.
  19. effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-strength-evidence.ppt
    June 01, 2012 - Another task in the first step is to choose the important outcomes that result from the testing encounter … Outcomes of Genetic Testing in Adults With a History of Venous Thromboembolism. … versus not testing is a tossup. … A simple decision model can be used to identify a threshold for which testing versus not testing is a … Outcomes of Genetic Testing in Adults With a History of Venous Thromboembolism.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-appendix-c-prepub-final.xlsx
    January 01, 2025 - included CT, ultrasound, blood testing, hepatitis testing, urine testing, ECG, mammogram, Pap smear) … Radiation exposure from PET-CT as potential harm of evaluation and additional testing. … Unclear Yes Unclear None NR Cancer patients had testing prior to any treatment. … NR Testing was performed prior to cancer treatment. … NR Testing occurred prior to any treatment.

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