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  1. effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1506.pdf
    December 01, 2015 - Standard basic testing for TB costs about $40, and drug susceptibility testing can add another $102 … As for susceptibility testing, compared with conventional culture-based susceptibility testing, the … Xpert MTB/RIF point-of- care testing had similar sensitivity to laboratory-based Xpert MTB/RIF testing … Xpert MTB/RIF into a TB diagnostic algorithm, TB testing without molecular testing was calculated … When all health-system costs were considered, TB testing without molecular testing was most costly
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_disposition-comments.pdf
    August 23, 2012 - Followup testing was omitted as an intervention in the definition of KQ5, but the use of FLC, SPEP ( … The frequency of follow up testing in the various risk groups is certainly an area for more research … The IMWG criteria for progression and relapse only use SFLC testing in the absence of any other signs … Peer Reviewer #2 General Our clinical practice has incorporated FLC assays into testing for PCD. … compared to standard testing alone.
  3. effectivehealthcare.ahrq.gov/products/cad-women-diagnosis/research-protocol
    December 08, 2010 - with exercise ECG is the oldest and most commonly used form of stress testing. … . 3 In summary, many factors affect the accuracy of diagnostic testing for CAD in women, 3 including … . 4 After undergoing coronary angiography, some patients may be referred for noninvasive stress testing … Role of noninvasive testing in the clinical evaluation of women with suspected coronary artery disease … ACC/AHA 2002 guideline update for exercise testing: summary article: a report of the American College
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis_research-protocol.pdf
    June 06, 2011 - with exercise ECG is the oldest and most commonly used form of stress testing. … diagnostic performance, ability to localize areas of ischemia, and the option of performing stress testing … .3 In summary, many factors affect the accuracy of diagnostic testing for CAD in women,3 including: … .4 After undergoing coronary angiography, some patients may be referred for noninvasive stress testing … ACC/AHA 2002 guideline update for exercise testing: summary article: a report of the American College
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_disposition-comments.pdf
    June 12, 2012 - Perhaps "NIT modality" or "testing modality" may better reflect what it is meant. … However it appears to involve statistical testing. … P-values arise from testing for presence of interactions. … Layered testing as a focus for future research must be emphasized along with appropriateness of testing … We agree and have already discussed layered testing in the Discussion section.
  6. effectivehealthcare.ahrq.gov/system/files/docs/na_liver_disease_topic_brief_topic_brief.pdf
    October 30, 2020 - We did not find a specific screening and testing strategy aimed at this population. … A testing algorithm for this population has been proposed (See Figure 1). … The options for next steps might be 1) no additional testing for NAFLD; 2) additional testing for everyone … who has abnormal LFTs; and 3) additional testing for those who are “high risk” by the definition given … In any case, if additional testing were done, it would be an ultrasound, since this test was not done
  7. effectivehealthcare.ahrq.gov/sites/default/files/Evidence%20Summary_1.pdf
    April 01, 2020 - However, such testing is time consuming and access is limited in some clinical settings. … the biomarker testing search covered from 2012 to March 2019. … No studies examined the accuracy of blood testing. … studies and few brain imaging or CSF testing studies reported on harms. … Studies should systematically collect data on potential harms of cognitive testing.
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_executive.pdf
    June 01, 2012 - In testing for a statistically significant difference between the diagnostic accuracy of testing modalities … In fact, multiple testing or layered-testing strategies are areas where significant research is needed … A comparison of a functional testing strategy to an anatomic testing strategy for patients with symptomatic … As stated previously, multiple testing or layered-testing strategies, plus the influence on risk- factor … More evidence about predictors affecting diagnostic cardiac testing is needed to support or dispel
  9. effectivehealthcare.ahrq.gov/products/procalcitonin/research-protocol
    April 26, 2011 - Adverse events of testing, such as pain, local bleeding, or infection? … Adverse events of testing, such as persistent or recurrent infection, and antibiotic resistance? … quality of life, and/or mortality) and link G (adverse events of testing). … An early link in an indirect chain of evidence concerns the diagnostic accuracy of testing (B). … HER2 Testing to Manage Patients With Breast Cancer or Other Solid Tumors.
  10. effectivehealthcare.ahrq.gov/products/musculoskeletal-complaints-tests-children/research-protocol
    September 29, 2010 - 2013 Surveillance Report Antinuclear Antibody, Rheumatoid Factor, and Cyclic-Citrullinated Peptide Testing … The scan identified two systematic reviews examining the use of ANA testing in JIA, one focused specifically … No systematic reviews examining ANA for pediatric SLE or RF and CCP testing for JIA were identified. … Antinuclear antibody (ANA) testing. Pediatr Rev 2003;24:320-1. Syed RH, Gilliam BE, Moore TL. … Anti-CCP antibody testing as a diagnostic and prognostic tool in rheumatoid arthritis.
  11. effectivehealthcare.ahrq.gov/health-topics/evidence-based-practice
    September 01, 2019 - and Lessons Learned White Paper February 11, 2019 Development and Usability Testing
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-quality-indicator-testing_research.pdf
    April 01, 2010 - Cancer Quality-ASSIST Supportive Oncology Quality Indicator Set: Feasibility, Reliability, and Validity Testing … Quality-ASSIST supportive oncology quality indicator set: feasibility, reliability, and validity testing … Cancer Quality-ASSIST supportive oncology quality indicator set: feasibility, reliability, and validity testing … had both reliability and validity issues, leaving a set of 41 indicators most promising for further testing … communication are very different from those assessing discrete, concrete events like fecal occult blood testing
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_technical-brief.pdf
    December 01, 2012 - What Important Issues are Raised by Using GEP Testing for Stage II Colon Cancer? … What Important Issues are Raised by Using GEP Testing for Stage II Colon Cancer? … • Is GEP testing a replacement or add-on technology? Guiding Question 2. … Is GEP Testing a Replacement or add-on Technology? … Adverse events of testing?
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-about-160226.pdf
    March 09, 2016 - N Field-testing was conducted with high-risk smokers who were eligible for lung cancer screening … but were not explicitly seeking screening. 23 Field-testing showed that the decision aid was acceptable … Y 24 Field-testing showed that people who were undecided felt that the information was presented … N Field-testing was conducted with high-risk smokers who were eligible for lung cancer screening … Leal, MPH Project Manager, Development and Testing Department of Health Services Research Division
  15. effectivehealthcare.ahrq.gov/sites/default/files/12_pregnancy_potential_high_impact_june_2012.pdf
    January 01, 2012 - Such testing is intended to help women avoid unnecessary, invasive followup testing that could pose …  Key Expert Comments: Overall, experts commenting on maternal blood-based fetal DNA testing viewed … However, a negative result could help some women avoid more invasive testing. … , this fetal DNA testing platform will likely not reduce health disparities. … Overall, experts saw potential for this intervention to significantly impact testing for trisomy 21 at
  16. effectivehealthcare.ahrq.gov/webform/products/mental-health-apps/submit-sead
    June 28, 2021 - Leave this field blank CAPTCHA This question is for testing whether or not you are a human visitor
  17. effectivehealthcare.ahrq.gov/products/celiac-disease/research-protocol
    June 11, 2014 - The validity and acceptability of the various diagnostic testing regimens and criteria have remained … Finally, in response to a comment about how previously negative testing affects test accuracy, we added … length of time ingesting gluten before diagnostic testing? … biopsy) or harms (related to false positives, false negatives, indeterminate results) associated with testing … FN Positive and negative likelihood ratios For KQ 1b, for clinical decision-making Additional testing
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/benefits-harms-modeling_research.pdf
    November 19, 2009 - This indirectness in the link between testing and its downstream effects poses practical challenges … Although testing in itself can affect outcomes directly,1 most of its impact is indirect. … Tradeoffs All testing procedures and treatment decisions are associated with benefits, risks, and … Direct effects include testing-induced emotional, cognitive, and behavioral changes or complications … Patient outcome after testing. Med Decis Making 2009;29(5):E30-E38 2.
  19. effectivehealthcare.ahrq.gov/products/hypertension-pulmonary-arterial/research
    April 25, 2013 - to evaluate the comparative validity, reliability, and feasibility of echocardiography and biomarker testing … accuracy and discrimination; however, one good-quality prospective cohort study suggested that biomarker testing … combination of echocardiography and the biomarker NT-proBNP is sufficiently accurate to rule out PAH when testing
  20. effectivehealthcare.ahrq.gov/products/health-data-mapping/protocol
    December 03, 2019 - Manufacturers of FDA regulated devices typically are required to demonstrate, through testing, that their … Direct (hands on) usability and performance testing will be restricted to those technologies that are … If there are no such technologies, then we will expand this testing to include any technologies that … Data Synthesis Direct (hands on) usability and performance testing will be restricted to those … If there are no such technologies, then we will expand this testing to include any technologies that

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