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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/wireless-motility-capsule_disposition-comments.pdf
    May 20, 2013 - Our decision to exclude breath testing was confirmed with the Key Informants. … WMC testing resulted in changes in management in 84% of patients. … as surrogates for motility testing or to exclude alarm conditions. … The Use of Colonic Testing to Guide Treatment in the Introduction chapter now states, “If testing confirms … “established” standards of upper and lower gut motility testing.
  2. effectivehealthcare.ahrq.gov/products/cancer-communication/research
    March 28, 2013 - independent SEG, and members had expertise in clinical cancer communication, survey design, cognitive testing … During pre-testing, the items functioned well overall. … The cancer patients who participated in the testing were generally able to understand the questions, … Additional steps are needed to finalize the items including additional cognitive testing, conducting
  3. effectivehealthcare.ahrq.gov/decision-aids/lung-cancer-screening/static/lung-cancer-screening-clin-checklist.pdf
    March 01, 2016 - Discussed potential harms of lung cancer screening, including: » False-positive results » Followup testing … if an abnormality is found (and the possible complications of invasive testing) » Overdiagnosis … » Total radiation exposure (screening and diagnostic testing, cumulative) Discussed other issues: … b Symptomatic patients may need followup and diagnostic testing, but not screening. … This could lead to treatment of people who do not really need treatment. » Screening and followup testing
  4. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/lung-cancer-screening-clin-checklist.pdf
    March 01, 2016 - Discussed potential harms of lung cancer screening, including: » False-positive results » Followup testing … if an abnormality is found (and the possible complications of invasive testing) » Overdiagnosis … » Total radiation exposure (screening and diagnostic testing, cumulative) Discussed other issues: … b Symptomatic patients may need followup and diagnostic testing, but not screening. … This could lead to treatment of people who do not really need treatment. » Screening and followup testing
  5. effectivehealthcare.ahrq.gov/decision-aids/lung-cancer-screening/static/lung-cancer-screening-decision-aid.pdf
    March 01, 2016 - If you have smoked for many years, you may want to think about screening (testing) for lung cancer with … What is the difference between screening and diagnostic testing? … Screening is a medical term for testing to find a disease before it causes any symptoms or problems. … Diagnostic testing is not the same as screening. … If the screening test is positive, additional testing may involve higher doses of radiation.
  6. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/lung-cancer-screening-decision-aid.pdf
    March 01, 2016 - If you have smoked for many years, you may want to think about screening (testing) for lung cancer with … What is the difference between screening and diagnostic testing? … Screening is a medical term for testing to find a disease before it causes any symptoms or problems. … Diagnostic testing is not the same as screening. … If the screening test is positive, additional testing may involve higher doses of radiation.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis-future_research_1.pdf
    February 01, 2013 - or layered-testing strategies)? … layered-testing strategies? … or layered-testing strategies)? … or layered-testing strategies? … multiple testing or layered-testing strategies?
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/making-healthcare-safer-IV.pdf
    August 04, 2023 - Additionally, owing to the overlapping findings of the C.difficile testing chapter in MHS III, our … rapid response will also subsume the C.difficile surveillance and testing topics as it relates to active … surveillance, along with screening and testing in asymptomatic patients. … in 2017, there has been an acceleration in publications evaluating C.difficile testing and diagnostic … of surveillance cannot be evaluated • Testing stewardship interventions • No microbial organism
  9. effectivehealthcare.ahrq.gov/health-topics/kidney-tests/
  10. Decision Modeling (ppt file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-decision-modeling.ppt
    June 01, 2012 - Links between testing, test results, and patient outcomes are complex. … Example: HIV testing Direct effects: Emotional distress from the testing process, cognitive/emotional … For example, testing for HIV has both direct and indirect effects. … summary testing performance (e.g., sensitivity, specificity). … The table shown classifies the results of PET testing.
  11. Decision Modeling (ppt file)

    effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-decision-modeling.ppt
    June 01, 2012 - Links between testing, test results, and patient outcomes are complex. … Example: HIV testing Direct effects: Emotional distress from the testing process, cognitive/emotional … For example, testing for HIV has both direct and indirect effects. … summary testing performance (e.g., sensitivity, specificity). … The table shown classifies the results of PET testing.
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/wireless-motility-capsule-future_research.pdf
    May 01, 2013 - We found two studies evaluating WMC as an add-on to other testing. … Consensus guidelines suggest that WMC testing is a replacement for current testing methods, however … The next series of questions asked about the incremental value of WMC testing in addition to other testingtesting. … We found two studies evaluating WMC as an add-on to other testing.
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_executive.pdf
    January 01, 2016 - Rapid Streptococcus Antigen Testing. … C-Reactive Protein Testing. … The combination of communication training and CRP testing was not different from CRP testing alone … + Procalcitonin testing + Rapid strep testing + Combination of patient and provider education plus audit … training, communication training plus CRP testing).
  14. effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-is-the-comparative-effectiveness-of-genetic-and-other-diagnostic-tests-to-identify-and-treat-intellectual-and-developmental-disabilities-caused-by-genetic-mutations-in-post-natal-to-early-childhood-populations
    October 26, 2012 - tests: Oligo- or SNP-based Chromosomal Microarray (CMA) High-resolution G-banded karyotype FMR1 testing … Determining this would address uncertainty policymakers and clinicians feel regarding the utility of genetic testing … One Medicaid director stated, "We have seen a significant number of claims for genetic testing in children … Our average reimbursement is approximately $1750.00 for this microarray testing. … Organization Please tell us how you heard about the Effective Health Care Program Genetic Testing
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_executive.pdf
    September 01, 2013 - Genetic testing for CYP2C19 ii. … Genetic testing for CYP2C19 followed by phenotypic testing for platelet reactivity iii. … Phenotypic testing for platelet reactivity iv. No testing b. … Use of phenotypic testing (but not genetic testing) as a monitoring test can be considered a variation … Combined Testing for CYP2C19 Variants and Phenotypic Testing To Guide Antiplatelet Treatment Of the
  16. effectivehealthcare.ahrq.gov/get-involved/nominated-topics/can-screening-among-the-general-adult-male-population-for-elevated-pca3-also-known-as-dd3-gene-expression-to-identify-those-at-risk-for-prostate-cancer-who-may-be-candidates-for-prostate-biopsy-reduce-morbidity-and-mortality
    July 29, 2010 - commercially available PCA3 expression assays for prostate cancer screening tests vs. screening by PSA testing … related outcomes resulting from improved/earlier detection of prostate cancer that may result from testing … Organization Please tell us how you heard about the Effective Health Care Program PCA3 Testing … in the Diagnosis and Management of Prostate Cancer: Future Research Needs PCA3 Testing for the Diagnosis
  17. effectivehealthcare.ahrq.gov/products/immunity-after-covid/protocol
    September 10, 2020 - Although testing for antibodies to SARS-CoV-2 is becoming more common, how these tests should be utilized … What are the unintended consequences of antibody testing after SARS-CoV-2 infection? Table 1. … Include: KQ 1,4: Adults with viral RT-PCR confirmed SARS-CoV-2 infection who underwent serologic testing … KQ 2-3: Adults with viral RT-PCR confirmed SARS-CoV-2 infection who underwent serologic testing using … Early in the pandemic, PCR testing was strictly done on symptomatic patients to conserve resources in
  18. effectivehealthcare.ahrq.gov/sites/default/files/whitepaper3-lijmer02262010-2.pdf
    January 01, 2009 - Premature dissemination of testing technologies can lead to erroneous diagnoses and preventable delays … The ultimate question in decisions about testing is how much net gain from testing there will be for … The benefits from testing may be limited to a subset of those tested, so sample size requirements can … be substantial.45 Trials of testing need a well-defined protocol that links testing, results, and downstream … All of these practical problems are challenging but not insurmountable, and trials of testing can be
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-tests-proposals_research.pdf
    January 01, 2009 - Premature dissemination of testing technologies can lead to erroneous diagnoses and preventable delays … The ultimate question in decisions about testing is how much net gain from testing there will be for … The benefits from testing may be limited to a subset of those tested, so sample size requirements can … be substantial.45 Trials of testing need a well-defined protocol that links testing, results, and downstream … All of these practical problems are challenging but not insurmountable, and trials of testing can be
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/celiac-disease_clinician.pdf
    July 01, 2016 - Testing for the presence of HLA-DQ2 or HLA-DQ8 has excellent sensitivity and negative predictive value … For children younger than 2 years, the ACG guidelines recommend initial testing with tTG IgA, DGP IgA … a Sensitivity and specificity values are for point-of-care testing. b Sensitivity and specificity values … a Sensitivity and specificity values are for point-of-care testing. b Sensitivity and specificity values … Testing algorithms �� All algorithms studied used tTG tests.

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