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  1. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/renal-function_research-protocol.pdf
    June 13, 2013 - Previous reviews and meta-analyses have investigated the prognostic performance of troponin testing … Note that for the population with suspected ACS (KQ 1-3), biomarker testing is done so routinely as … part of standard care that “no testing” is not a realistic comparator. … hs troponin I Troponin testing in CKD vs non-CKD Troponin testing vs. … • For the population with suspected ACS (KQ 1-3), biomarker testing is done so routinely as part
  2. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/echocardiography_research.pdf
    May 01, 2014 - 12 The criteria vary by previous service and clinical indication, but in gen- eral echocardiography testing … unclear - in the case of stress echo- cardiography, the relationship between the office location of testing … material and increased cost of care after testing is modest.13 However, evidence indicates that physicians … : an empiric analysis of cardiac stress testing with imaging. … Repeat testing among Medicare beneficiaries. Arch Intern Med 2012;172(22):1745-51. 19.
  3. effectivehealthcare-admin.ahrq.gov/products/methods-guide-editorial/methods
    December 01, 2019 - compared to a reference standard, in this case, invasive angiography) and the downstream result of testing
  4. effectivehealthcare-admin.ahrq.gov/products/liver-cancer/research-protocol
    December 01, 2019 - Surveillance is the use of periodic testing to monitor lesions in the liver that give rise to a clinical … What are the adverse effects or harms associated with using imaging techniques related to testing or … Psychosocial effects of diagnostic testing on patients, patients’ caregivers, and other family members … Psychosocial effects of diagnostic testing on patients, patients’ caregivers, and other family members … Psychosocial effects of diagnostic testing on patients, patients’ caregivers, and other family members
  5. effectivehealthcare-admin.ahrq.gov/health-topics/radon
    Testing is the only way to know if your home has elevated radon levels. It is inexpensive and easy.
  6. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-performance_methods.pdf
    July 01, 2012 - screening performance of the test, it quantifies the impact of patient management strategies that include testing … PSA levels are not elevated in as many as 15 percent of individuals with prostate cancer, making PSA testing
  7. effectivehealthcare-admin.ahrq.gov/products/cancer-pancreas/research-protocol
    January 01, 2020 - factors (e.g., Peutz-Jeghers syndrome, Lynch syndrome, and BRCA2, PALB2, and p16 mutations) motivate testingTesting for recurrent pancreatic cancer is excluded. … diagnostic errors/ or exp diagnostic error/) 34 Pancreatic cancer and imaging and diagnostic testing
  8. effectivehealthcare-admin.ahrq.gov/products/renal-function/research-protocol
    December 01, 2019 - Previous reviews and meta-analyses have investigated the prognostic performance of troponin testing in … as part of standard care that “no testing” is not a realistic comparator. … In KQ 4, one comparator of interest would be “no testing” beyond the use of a standard risk-predictor … For the population with suspected ACS (KQs 1–3), biomarker testing is done so routinely as part of a … standard workup that “no testing” is not a realistic comparator and thus will not be evaluated.
  9. effectivehealthcare-admin.ahrq.gov/products/methods-future-research-steps-framework/research
    December 01, 2019 - During pilot-testing, we identified challenges including difficulty in applying the framework for completed … Further testing should determine if these challenges are ameliorated if the framework is used during
  10. effectivehealthcare-admin.ahrq.gov/products/febrile-infants-diagnosis-management/research
    December 01, 2019 - Harms associated with testing or management strategies have been less well studied. … Future studies should focus on identifying the risks associated with testing and management strategies
  11. effectivehealthcare-admin.ahrq.gov/products/prostate-cancer-surveillance/research
    December 01, 2019 - Increased diagnosis of early-stage prostate cancer due to prostate-specific antigen (PSA) testing, led … different monitoring protocols, all with different combinations of periodic digital rectal examination, PSA testing
  12. effectivehealthcare-admin.ahrq.gov/health-topics/blood-count-tests
    November 09, 2009 - Report November 9, 2009 Additional Patient Outcomes and Alternative Pathways in Evaluations of Testing
  13. effectivehealthcare-admin.ahrq.gov/health-topics/leukodystrophies
    Researchers are testing bone marrow transplantation as a treatment for some of the leukodystrophies.
  14. effectivehealthcare-admin.ahrq.gov/health-topics/heart-diseases?page=0
    June 21, 2018 - Diabetic Peripheral Neuropathy Systematic Review Archived March 29, 2016 Noninvasive Testing … Artery Stenosis Update Research Protocol Archived January 15, 2015 Noninvasive Testing
  15. effectivehealthcare-admin.ahrq.gov/health-topics/heart-attack
    November 14, 2017 - Depression: A Systematic Review Systematic Review Archived March 29, 2016 Noninvasive Testing … Coronary Artery Disease Research Protocol Archived January 15, 2015 Noninvasive Testing
  16. effectivehealthcare-admin.ahrq.gov/health-topics/heart-diseases
    June 21, 2018 - Diabetic Peripheral Neuropathy Systematic Review Archived March 29, 2016 Noninvasive Testing … Artery Stenosis Update Research Protocol Archived January 15, 2015 Noninvasive Testing
  17. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cell-free-dna-appendices.pdf
    May 22, 2024 - stool-based tests (colorectal), low- dose computed tomography (lung), cytology, human papilloma virus testing … Sensitivity TP/(TP+FN) Proportion of persons with cancer testing positive on the MCST; ranges from … Specificity TN/(TN+FP) Proportion of persons without cancer testing negative on the MCST; ranges from … Early real-world experience with repeat multi- cancer early detection (MCED) testing. … Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention.
  18. effectivehealthcare-admin.ahrq.gov/products/musculoskeletal-disorders-imaging/research-protocol
    December 01, 2019 - What are the postulated advantages and disadvantages of positional MRI testing compared to contemporary … Guiding question 2: What is the current availability and cost of positional MRI testing and what are … Approximately how many facilities and of what kind are currently providing positional MRI testing in … used Study design and size Role of the test in patient management Setting where positional MRI testing … Moreover, we will record the outcomes being assessed in each study, including testing related harms,
  19. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/diagnostic-tests-accuracy_research.pdf
    January 01, 2013 - algorithms in the frequentist and Bayesian settings, using approximate and discrete likelihoods to model testing … 1 Background The value of diagnostic testing for patient management ultimately derives from its effect … Testing primarily affects outcomes by indirect means, influencing downstream patient management decisions … , including decisions for further testing, and administration or choice of treatment. … screening programs do not rely on isolated markers, but combine sequential biochemical and ultrasound testing
  20. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/colon-cancer-gene-profiling_disposition-comments.pdf
    December 14, 2012 - I did wonder why at several times the idea of only testing T3 tumors without MSI was mentioned instead … of suggesting that testing be restricted to all Stage II tumors without MSI but since it was just a … Most of the studies were for prognostic testing, but predictive testing is the more important clinical … in or..” such that the first sentence would be changed to, “Because the topic of this Brief is GEP testing … Clarification of “patients for testing” will be very important as clinical algorithms for use of GEP

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