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Showing results for "testing".

21. Noninvasive Testing for Coronary Artery Disease | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/coronary-artery-disease-testing/research-protocol
    December 01, 2019 - Some types of noninvasive testing (e.g., stress testing) provide additional information not provided … , imaging stress testing, or no further testing? … or no further testing. … (both initial and subsequent testing): Harms of testing (renal failure, allergy, nephrogenic … Consequences of testing may also include use of downstream testing, anxiety related to false positives

22. Data Points #15: Prognostic factor testing among older women with ductal carcinoma in situ and early invasive breast cancer | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/dcis-prognostic-tests/research
    December 01, 2019 - Rates of testing varied significantly across race groups for all tests. … Neither study included ER testing. … ER testing is considered standard of care for women with early invasive cancer. … Studies of PR testing are inconclusive in the context of DCIS. … and to better understand how testing rates differ between both groups.

23. Does the use of Cytochrome P450 2C19 (CYP2C19) testing to predict response to clopidogrel in people: (1) with acute coronary syndrome, (2) who have suffered other cardiovascular disease-related events (e.g., ischemic stroke, symptomatic… | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/does-the-use-of-cytochrome-p450-2c19-cyp2c19-testing-to-predict-response-to-clopidogrel-in-people-1-with-acute-coronary-syndrome-2-who-have-suffered-other-cardiovascular-disease-related-events-eg-ischemic-stroke-symptomatic-
    November 01, 2017 - Nominated Topics Does the use of Cytochrome P450 2C19 (CYP2C19) testing … SHARE: Does the use of Cytochrome P450 2C19 (CYP2C19) testing … Does the use of Cytochrome P450 2C19 (CYP2C19) testing to predict response to clopidogrel in people: … you would like to see compared: Health outcomes following therapy guided by CYP2C19 pharmacogenetic testing … , to predict clopidogrel response, versus a no-testing strategy.

24. Key Questions 1. Does routine preoperative testing compared to no testing or alternative testing strategies improve outcomes (such as surgical complications, other morbidity, and mortality) among patients undergoing elective surgery? 2.… | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/key-questions-1-does-routine-preoperative-testing-compared-to-no-testing-or-alternative-testing-strategies-improve-outcomes-such-as-surgical-complications-other-morbidity-and-mortality-among-patients-undergoing-elective-surg
    November 01, 2017 - Does routine preoperative testing compared to no testing or alternative testing strategies improve outcomes … Does routine preoperative testing compared to no testing or alternative testing strategies improve outcomes … Key Questions Does routine preoperative testing compared to no testing or alternative testing strategies … What are the harms of routine preoperative testing compared to no testing or to an alternative testing … compared to no testing or alternative testing.

25. Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/antiplatelet-treatment/research
    December 01, 2019 - for CYP2C19 variants and phenotypic testing to measure platelet reactivity) to identify patients who … (for CYP2C19 variants) or phenotypic testing (for platelet reactivity). … One hundred six studies provided information on the ability of genetic testing for CYP2C19 variants to … Fourteen studies provided information on the use of genetic testing for CYP2C19 variants for guiding … treatment choice: 1 randomized trial of testing versus no testing, 12 randomized treatment trials assessing

26. Data Points 15: Breast Cancer Diagnostic Workup: Prognostic factor testing among older women with ductal carcinoma in situ and early invasive breast cancer (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/dcis-prognostic-tests_research.pdf
    August 22, 2012 - Estrogen and Progesterone Receptor Testing Rates of ER/PR testing for women with DCIS varied strongly … HER2 Testing As with ER/PR testing, HER2 testing increased dramati- cally among women with DCIS between … BRCA Testing We found a low rate (0.6%) of BRCA testing among women with DCIS. … and are thus testing randomly. … Data Points • # 15 • Breast Cancer Diagnostic Workup 14 Appendix D: ER/PR testing and HER2 testing

27. Comparative Effectiveness of Fecal DNA Testing in Screening for Colorectal Cancer in Average-Risk Adults | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/colorectal-cancer-screening/research-protocol
    December 01, 2019 - (FOBT) or fecal immunohistochemical testing (FIT) annually; and flexible sigmoidoscopy every 5 years … with or without fecal blood testing (FOBT or FIT). 3, 4 Some disagreement occurs between guideline … . 3 Fecal DNA testing detects molecular alterations associated with CRC development in cellular DNA … Question 6: Harms What are the potential harms of fecal DNA testing? … FOBT = Fecal Occult-Blood Testing USPSTF = U.S.

28. Topic 0505 Genetic Testing for Developmental Diseases NSD FINAL_SJ (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0594-131115.pdf
    March 13, 2013 - Topic 0505 Genetic Testing for Developmental Diseases NSD FINAL_SJ … § Genetic Testing for Developmental Diseases Nomination Summary Document … Results of Topic Selection Process & Next Steps  The topic, Genetic Testing … Comparator(s): Other genetic testing/no genetic testing Outcome(s): Changes to child treatment specific …  Given the limited available evidence, the rapid pace of change in genetic testing, and the recent

29. Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/antiplatelet-treatment/research-protocol
    December 01, 2019 - Randomized trials of testing strategies versus no-testing strategies can address the question of whether … the use of testing (e.g., genetic testing to determine CYP2C19 status or phenotypic testing of platelet … Genetic testing for CYP2C19 Genetic testing for CYP2C19 followed by phenotypic testing for platelet … reactivity Phenotypic testing for platelet reactivity No testing How do modifying factors … In the context of this review, phenotypic testing specifically refers to testing of platelet reactivity

30. Chapter 3: Choosing the Important Outcomes for a Systematic Review of a Medical Test | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/methods-guidance-tests-outcomes/methods
    October 01, 2019 - Consider to which group the outcomes of testing are most relevant. … Legal and ethical effect of testing. … Legal and ethical effects of testing. … Legal and ethical effects of testing. … Additional patient outcomes and pathways in evaluations of testing.

31. Executive Summary CER 171: Noninvasive Testing for Coronary Artery Disease (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/coronary-artery-disease-testing_executive.pdf
    March 01, 2011 - Additional Noninvasive Testing Additional noninvasive testing, which impacts the cost and efficiency … Harms and Consequences of Testing Harms of testing were rarely reported and details on comparisons of … No studies that compared testing with an arm that received no testing were identified, so the impact … Studies comparing testing versus clinical evaluation without testing would provide valuable information … for assessing the need for testing, possible overuse of testing, and the impact of testing in general

32. PCA3 Testing for the Diagnosis and Management of Prostate Cancer | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/prostate-cancer-test/research-protocol
    December 01, 2019 - These programs are based on the premise that PSA testing can lead to early detection of prostate cancer … However, testing total PSA levels to decide which patients should undergo a biopsy has been found to … by and used at a single laboratory testing site). … The Key Questions (KQs) present three proposed scenarios in which this testing may be used. … Note: PCA3 testing has not been approved by the FDA but is offered as a laboratory-developed test.

33. 13-MDM347013 30..38 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/outcomes-testing-evaluation_research.pdf
    January 01, 2009 - Some effects from testing are direct. … A study of genetic testing for BRCA1 and BRCA2 found that women testing positive for a mutation reported … Behavioral Effects of Testing The emotional, social, and cognitive effects of testing may also affect … In this, testing is no exception. … Most of these frameworks look at determinants of testing, however, not at the effects of testing.

34. 13-MDM347013 30..38 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/whitepaper4-bossuyt02262010-2.pdf
    January 01, 2009 - Some effects from testing are direct. … A study of genetic testing for BRCA1 and BRCA2 found that women testing positive for a mutation reported … Behavioral Effects of Testing The emotional, social, and cognitive effects of testing may also affect … In this, testing is no exception. … Most of these frameworks look at determinants of testing, however, not at the effects of testing.

35. Effective Health Care (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0411_02-10-2011.pdf
    January 01, 2011 - 09-12-11 1 Results of Topic Selection Process & Next Steps  Routine preoperative testing … improves patient outcomes compared to patients receiving no preoperative testing or alternative testing … Does routine preoperative testing compared to no testing or alternative testing strategies improve outcomes … What are the harms of routine preoperative testing compared to no testing or to an alternative testing …  No recent comprehensive review related to preoperative testing in ambulatory surgery patients

36. Effective Health Care (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0334_08-04-2010.pdf
    January 01, 2010 - Date: 3-22-11 1 Results of Topic Selection Process & Next Steps  Pharmacogenetic testing … Intervention(s): Genetic testing for CYP2C19 variants to guide treatment selection. … Comparator(s): A no-testing (for CYP2C19 variants) strategy or a strategy of testing for Pharmacogenetic … who are candidates for clopidogrel treatment, compared to alternative testing strategies or a no-testing … strategies or a no- testing strategy?

37. Wireless Motility Capsule Versus Other Diagnostic Technologies for Evaluating Gastroparesis and Constipation: A Comparative Effectiveness Review | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/wireless-motility-capsule/research-protocol
    December 01, 2019 - Whether it can replace or should supersede other testing methods is controversial. … An advantage of colon scintigraphy is that testing can be completed in 1 to 2 days. … Other testing might be required to ensure that no narrowing is present. … , then the next step in evaluation is transit testing with use of laxatives. … motility capsule testing, and identify them for physicians and payers.

38. Interventions To Improve Antibiotic Prescribing for Uncomplicated Acute Respiratory Tract Infections | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/antibiotics-respiratory-infection/clinician
    December 01, 2019 - for procalcitonin testing in children increased antibiotic prescribing and adverse consequences. … Clinical Interventions (Point-of-Care Testing): Procalcitonin point-of-care testing in adults reduced … Streptococcal antigen point-of-care testing (rapid strep testing) reduced overall prescribing by 20 to … Rapid viral point-of-care testing (multi-viral PCR) in adults reduced overall prescribing by 8 percent … vs. usual care Overall prescribing -1.9% to -33.5% Greater reduction with CRP testing: RR 0.73

39. Methods Guide for Medical Test Reviews Chapter 3 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-outcomes_methods.pdf
    July 01, 2012 - Direct health effects of testing Emotional, cognitive, social, behavioral re- sponses to testing … Legal, ethical effects of testing Costs Outcome Origins From Testing Process From Test Results … Legal and ethical effect of testing. … Legal and ethical effects of testing. … Legal and ethical effects of testing.

40. PCA3 Testing in the Diagnosis and Management of Prostate Cancer: Future Research Needs (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/prostate-cancer-antigen-3-gene_research.pdf
    April 01, 2013 - Patients with elevated PCA3 values PCA3 testing Current standard of care without PCA3 testing … aggressive therapy PCA3 testing Current standard of care without PCA3 testing Decision to biopsy … Patients with elevated PCA3 values PCA3 testing Current standard of care without PCA3 testing … or standard testing alone. … or standard testing alone.