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effectivehealthcare-admin.ahrq.gov/products/immunity-after-covid/rapid-review
April 01, 2023 - What are the unintended consequences of antibody testing after SARS-CoV-2 infection? … Most studies did not perform protocolized follow-up testing designed to capture all incident infections … Antibody testing has been proposed as a potential marker or correlate of protection against infection … In these situations, the prognostic value of antibody testing was identical to the prognostic value of … settings when the timing of testing in relation to infection is unknown.
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effectivehealthcare-admin.ahrq.gov/products/mrsa-screening/research
December 01, 2019 - The screening strategy may use a testing modality with a rapid turnaround time (results available on … the same day as the testing is performed, typically using polymerase chain reaction (PCR), intermediate … turnaround time (results available next day to 2 days after testing performed) or longer turnaround … time (results available greater than 2 days after testing performed, typically culture).
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effectivehealthcare-admin.ahrq.gov/sites/default/files/whitepaper3-lijmer02262010-2.pdf
January 01, 2009 - Premature dissemination of testing technologies can lead
to erroneous diagnoses and preventable delays … The ultimate question in
decisions about testing is how much net gain from testing there will be for … The benefits from testing may be limited to a subset of those tested, so sample size
requirements can … be substantial.45 Trials of testing need a well-defined protocol that links testing,
results, and downstream … All of these practical problems
are challenging but not insurmountable, and trials of testing can be
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/medical-tests-proposals_research.pdf
January 01, 2009 - Premature dissemination of testing technologies can lead
to erroneous diagnoses and preventable delays … The ultimate question in
decisions about testing is how much net gain from testing there will be for … The benefits from testing may be limited to a subset of those tested, so sample size
requirements can … be substantial.45 Trials of testing need a well-defined protocol that links testing,
results, and downstream … All of these practical problems
are challenging but not insurmountable, and trials of testing can be
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effectivehealthcare-admin.ahrq.gov/products/musculoskeletal-complaints-tests-children/research-protocol
December 01, 2019 - Reports
Antinuclear Antibody, Rheumatoid Factor, and Cyclic-Citrullinated Peptide Testing … Antinuclear Antibody, Rheumatoid Factor, and Cyclic-Citrullinated Peptide Testing … No systematic reviews examining ANA for pediatric SLE or RF and CCP testing for JIA were identified. … Antinuclear antibody (ANA) testing. Pediatr Rev 2003;24:320-1.
Syed RH, Gilliam BE, Moore TL. … Anti-CCP antibody testing as a diagnostic and prognostic tool in rheumatoid arthritis.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/celiac-disease_clinician.pdf
July 01, 2016 - Testing for the presence of HLA-DQ2 or HLA-DQ8 has excellent
sensitivity and negative predictive value … For
children younger than 2 years, the ACG guidelines recommend
initial testing with tTG IgA, DGP IgA … a Sensitivity and specificity values are for point-of-care testing.
b Sensitivity and specificity values … a Sensitivity and specificity values are for point-of-care testing.
b Sensitivity and specificity values … Testing algorithms
�� All algorithms studied used tTG tests.
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effectivehealthcare-admin.ahrq.gov/products/asthma-nitric-oxide/research-protocol
June 01, 2021 - the diagnosis of asthma is challenging, given their inability to participate in the usual diagnostic testing … In children ages 0-4 years with recurrent wheezing, how accurate is FeNO testing in predicting the future … Comparators
KQ 1a: Standard diagnostic testing of asthma made by healthcare providers based on history … Use of bronchodilators prior to FeNO testing
Whether appropriate testing protocol was followed ( … We will iteratively continue testing the form until no additional items or unresolved questions exist
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effectivehealthcare-admin.ahrq.gov/products/mhs4-active-infection/protocol
September 01, 2023 - Additionally, owing to the overlapping findings of the C.difficile testing chapter in MHS III, our … surveillance, along with screening and testing in asymptomatic patients. … in 2017, there has been an acceleration in publications evaluating C.difficile testing and diagnostic … outside of outbreak surveillance testing Multicomponent interventions in which the isolated effect of … surveillance cannot be evaluated Testing stewardship interventions No microbial organism of interest
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rtc-design-principles_research.pdf
January 01, 2009 - Critical steps in the pathway between testing and patient
outcomes, such as differences in test accuracy … These RCTs should have long-term followup to capture all
immediate and downstream consequences of testing … It may involve no prior testing if the
new test is intended for primary screening or for monitoring … Other pathways
It is possible that the availability of D-dimer lowers the threshold for testing in … Additional patient outcomes and
pathways in evaluations of testing.
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effectivehealthcare-admin.ahrq.gov/products/cad-women-diagnosis/research-protocol
December 01, 2019 - with exercise ECG is the oldest and most commonly used form of stress testing. … . 3 In summary, many factors affect the accuracy of diagnostic testing for CAD in women, 3 including … . 4 After undergoing coronary angiography, some patients may be referred for noninvasive stress testing … Role of noninvasive testing in the clinical evaluation of women with suspected coronary artery disease … ACC/AHA 2002 guideline update for exercise testing: summary article: a report of the American College
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effectivehealthcare-admin.ahrq.gov/sites/default/files/brooks_eccs2012.pdf
January 01, 2012 - Slide 13: Patient Decision Aid
Image of Testing for Prostate Cancer: “Should
I be tested? … men.
• There are
tests
to
find it early.
• We don’t
yet
know
if the benefits of testing … outweigh the risks.
• Men
should learn
about
prostate cancer and testing,
then
decide … if testing
is
the right
choice for them.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/study-design-classification_research.pdf
December 01, 2010 - from the 30 studies used for the first round of
testing. … The
same analyses were conducted for the second round of testing. … Pilot testing the tool in the context
of each review is highly recommended. … The same analyses were conducted for the second round of testing. … We made minor revisions following the final round
of testing that merit further testing.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
September 08, 2011 - Direct evidence of the impact of testing on
health outcomes is shown by link A (morbidity, function … , quality of life and/or mortality)
and link G (adverse events of testing). … An early link
in an indirect chain of evidence concerns the diagnostic accuracy of testing (B). … HER2 Testing to Manage Patients With Breast Cancer or Other Solid
Tumors. … The
harms of the testing procedure itself
would relate to venipuncture.
II.
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effectivehealthcare-admin.ahrq.gov/products/medical-tests-proposals/research
December 01, 1969 - Premature dissemination of testing technologies can lead to erroneous diagnoses and preventable delays … The ultimate question in decisions about testing is how much net gain from testing there will be for … The benefits from testing may be limited to a subset of those tested, so sample size requirements can … be substantial. 45 Trials of testing need a well-defined protocol that links testing, results, and … It is inevitable that such trials evaluate the effectiveness of testing as well as that of downstream
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/test-performance-metrics_appendixes.pdf
January 01, 2005 - Sensitivity and Specificity
Sensitivity, also known as the true positive rate, is the probability of testing … Specificity,
or true negative rate, is the probability of testing negative for non-diseased patients
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-disposition-comments.pdf
October 25, 2022 - Since the report did not contain a Key Question
or Contextual Question about genetic testing, it
would … We did look through our database and
identified some studies of genetic testing and
genome sequencing … We did look through our database and
identified some studies of genetic testing and
genome sequencing … We did look through our database and
identified some studies of genetic testing and
genome sequencing … Thank you for this comment, AHRQ may consider
genetic testing for future reports.
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effectivehealthcare-admin.ahrq.gov/products/echocardiography/research
December 01, 2019 - The criteria vary by previous service and clinical indication, but in general echocardiography testing … The presence of testing equipment for echocardiography in primary care offices has been hypothesized … still unclear - in the case of stress echocardiography, the relationship between the office location of testing … material and increased cost of care after testing is modest.
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effectivehealthcare-admin.ahrq.gov/products/asthma-nitric-oxide/research
October 01, 2019 - Using FeNO cutoffs of <20, 20-30, 30-40, =40 part per billion (ppb); respectively, FeNO testing had sensitivities … FeNO testing may identify patients who were more likely to respond to inhaled corticosteroids (SOE: Low … FeNO testing predicted exacerbations in patients undergoing ICS reduction or withdrawal. … The Diagnostic Accuracy of Fractional Exhaled Nitric Oxide Testing in Asthma: A Systematic Review and
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effectivehealthcare-admin.ahrq.gov/products/immunity-after-covid/protocol
June 01, 2021 - Although testing for antibodies to SARS-CoV-2 is becoming more common, how these tests should be utilized … What are the unintended consequences of antibody testing after SARS-CoV-2 infection?
Table 1. … KQ 2-3: Adults with viral RT-PCR confirmed SARS-CoV-2 infection who underwent serologic testing using … We revised our definition of reinfection to be more representative of testing capabilities in real-world … Early in the pandemic, PCR testing was strictly done on symptomatic patients to conserve resources in
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/prostate-cancer-test_executive.pdf
April 01, 2013 - 1
Comparative Effectiveness Review
Number 98
PCA3 Testing for the Diagnosis
and Management of Prostate … subjects/populations (at-risk men
or men with a positive biopsy); (3) study interventions
(biomarker testing … KQ 3: Testing PCA3 and Comparators To Identify
Men With Insignificant Cancer Who May Benefit
From Active … Screening for prostate cancer
with prostate-specific antigen testing: American Society of Clinical … PCA3 Testing for the
Diagnosis and Management of Prostate Cancer.