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1. Final Research Plan: Vision in Children Ages 6 Months to 5 Years: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/vision-screening-children-ages-6-months-5-years
   July 24, 2025 - , pupillary reflex test, cover-uncover test, cross cover test, red reflex test).stereotests, such as … the Titmus Fly tests, and ocular alignment tests (e.g., corneal light reflex test, pupillary reflex test … , cover-uncover test, cross cover test, red reflex test). … risk factors, or refractive error (e.g., white reflex test) KQs 2, 3: Studies exclusively assessing … ), the comparison may be the same test administered at different timepoints or by a different person

2. Draft Research Plan: Cervical Cancer: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/cervical-cancer-screening-adults-adolescents
   October 28, 2021 - What is the comparative effectiveness of different cervical cancer screening strategies (i.e., test … What is the test accuracy of and adherence to self-collected high-risk HPV vaginal samples? … Does the test accuracy or adherence vary by population (e.g., by age, gender, race and ethnicity, or … What are the comparative harms of different cervical cancer screening strategies (i.e., test, mode of … What is the comparative test accuracy of high-risk HPV tests used in U.S.

3. Final Research Plan: Colorectal Cancer: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/colorectal-cancer-screening
   May 16, 2019 - ; gFOBT=guaiac-based fecal occult blood test; m SEPT9 =methylated septin 9 gene DNA; sDNA test (+/- FIT … )= stool DNA test with or without FIT; SSP=sessile serrated polyp. … How are newer screening tests (e.g., stool DNA test with or without fecal immunochemical test, or computed … Fecal immunochemical test (quantitative and qualitative testing) Multitarget stool DNA test (with … DNA test (m SEPT9 ) * Urine-based test KQs 2, 3: New technologic enhancements to colonoscopy

4. Summary of USPSTF Draft Recommendation: Screening for Cervical Cancer (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/3UuREAobGvgLbE_FBAnrYQ
   January 13, 2025 - A Pap test is done with a swab of the cervix, usually at the same time as a pelvic exam. … This type of screening test needs to be done by a healthcare professional. … • Co-testing is a type of screening that combines an HPV test and a Pap test. … • Women ages 30–65 should ideally get an HPV test every 5 years. … Alternatively, they can get a Pap test every 3 years or co-testing test every 5 years.

5. Draft Research Plan: Vision in Children Ages 6 Months to 5 Years: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/vision-screening-children-ages-6-months-5-years
   April 24, 2025 - , including: visual acuity tests (e.g., autorefraction; picture identification tests, such as Allen test … ); and ocular alignment tests (e.g., corneal light reflex test, pupillary reflex test, cover-uncover … test, cross cover test, red reflex test) Studies assessing photoscreeners for screening will be included … risk factors, or refractive error (e.g., white reflex test) KQs 2, 3: Studies exclusively assessing … ), the comparison may be the same test administered at different timepoints or by a different person

6. Evaluating Test Strategies for Colorectal Cancer Screening: A Decision Analysis (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/UPu84CV2CNuxR8kpVU6e3V
   November 01, 2008 - Evaluating Test Strategies for Colorectal Cancer Screening: A Decision Analysis Evaluating Test Strategies … for that lesion and whether the lesion is within the reach of the test. … These variations re- sulted in 145 strategies: 90 single-test strategies, 54 com- bination-test strategies … of specificity and the sensitivity of the test for the present lesions. … for adenomas by size or for cancer and the reach of the test.

7. Final Research Plan: Cervical Cancer: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cervical-cancer-screening-adults-adolescents
   March 17, 2022 - What is the comparative effectiveness of different cervical cancer screening strategies (i.e., test … What is the test accuracy of and adherence to self-collected high-risk HPV vaginal samples? … Does the test accuracy or adherence vary by population (e.g., by age, gender, race and ethnicity, or … What are the comparative harms of different cervical cancer screening strategies (i.e., test, mode of … What is the comparative test accuracy of high-risk HPV tests used in U.S.

8. Evidence Summary: Colorectal Cancer: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary19/colorectal-cancer-screening
   May 18, 2021 - compared with no screening; and (3) comparative trials of one screening test vs another screening test … For KQ2, the analyses primarily focused on per-person test accuracy of a single test application to detect … Serum Test Currently, one serum test—Epi proColon (Epigenomics)—is available to screen average-risk … In general test accuracy studies to clarify any differential in detection of proximal vs distal test … Screening test: Screening test was out of scope. Quality: Study was poor quality.

9. Final Research Plan: Syphilis Infection in Nonpregnant Adolescents and Adults: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/syphilis-infection-nonpregnant-adults-adolescents-screening
   January 28, 2021 - What are the harms of screening (e.g., stigma, sequelae of test inaccuracy)? … are the benefits and tradeoffs of screening with reverse sequence testing (i.e., using a treponemal test … for initial screening followed by a nontreponemal test for confirmation) compared to the traditional … sequence testing algorithm (i.e., a nontreponemal test followed by a treponemal test)? … What is the clinical test performance of rapid point-of-care antibody tests?

10. Evidence Summary: Syphilis Infection During Pregnancy: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/syphilis-infection-in-pregnancy-screening
    May 13, 2025 - of false-positive results ranged between 0% and 65%, varying by the index test evaluated and to which … algorithm the index test was compared. … test) reported a false-positive rate of 31% (11/35) for the initial nontreponemal test compared with … the treponemal test. … test) reported false-positive rates that varied substantially (7%-65%).

11. Screening for Gestational Diabetes: Clinician Summary for USPSTF Recommendation (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/qPSAJPnBVmzFneXUDMRJfs
    August 01, 2021 - gestational diabetes by using 1 of several methods: • A 2-step process that involves a screening test … (oral glucose challenge test) followed by a diagnostic test (oral glucose tolerance test). … • A 1-step process where the diagnostic test (oral glucose tolerance test) is administered to all patients

12. JAMA (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/eko8Cp28pZ3SHHfyvTXJW5
    May 13, 2025 - of false- positive results ranged between 0% and 65%, varying by the in- dex test evaluated and to which … algorithm the index test was compared. … test) reported a false-positive rate of 31% (11/35) for the initial nontreponemal test compared with … the treponemal test. … test) reported false- positive rates that varied substantially (7%-65%).

13. Clinical Summary: Screening for Syphilis Infection in Pregnant Women (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/dwyoU5ur5oQM69fH8GoaSc
    The traditional approach is to perform an initial “nontreponemal” antibody test (ie, Venereal Disease … Research Laboratory [VDRL] test or rapid plasma reagin [RPR] test), follow ed by a confirmatory “treponemal … ” antibody detection test (ie, f luorescent treponemal antibody absorption test or Treponema pallidum … particle agglutination test). … If the test results are discordant, a second treponemal test is performed.

14. Screening for Colorectal Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/DYFdTVu-UY3h7CWGdA7Zkh
    July 20, 2021 - compared with no screening; and (3) comparative trials of one screening test vs another screening test … For KQ2, the analyses primarily focused on per-person test ac- curacy of a single test application to … Screening test: Screening test was out of scope. Quality: Study was poor quality. … Serum Test Currently, one serum test—Epi proColon (Epigenomics)—is avail- able to screen average-risk … In general test accuracy studies to clarify any differential in detection of proximal vs distal test

15. Archived: Evaluating Test Strategies for Colorectal Cancer Screening: A Decision Analysis for the U.S. Preventive Services Task Force: Colorectal Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evaluating-test-strategies-for-colorectal-cancer-screening-a-decision-analysis-for-the-us-preventive-services-task-force/colorectal-cancer-screening-2008
    October 15, 2008 - to WhatsApp Share to Email Print archived Evaluating Test … for that lesion and whether the lesion is within the reach of the test. … These variations resulted in 145 strategies: 90 single-test strategies, 54 combination-test strategies … of specificity and the sensitivity of the test for the present lesions. … for adenomas by size or for cancer and the reach of the test.

16. Draft Recommendation: Syphilis Infection During Pregnancy: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/syphilis-infection-pregnant-persons
    November 19, 2024 - Screening Tests Screening for syphilis involves a blood test that detects antibodies to the organism … A traditional screening algorithm is a two-step process that begins with a nontreponemal test (e.g. … test results. … immunoassay) for the initial screening, followed by a nontreponemal test for reactive samples. … A new rapid home test has also been recently approved by the U.S.

17. Screening for Syphilis Infection in Nonpregnant Adolescents and Adults (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/tmpufJqkzbptG4uBtSGnam
    September 01, 2022 - (eg, Venereal Disease Research Laboratory [VDRL] or rapid plasma reagin [RPR] test). … If positive, confirm with a treponemal antibody detection test (eg, T pallidum particle agglutination … [TP-PA] test) … • Reverse sequence algorithm: Screen with an initial automated treponemal test (eg, enzyme-linked … If positive, confirm with a nontreponemal test.

18. Screening for Colorectal Cancer: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/Xbtq4oDQwVo7KgmSjnnDbz
    November 01, 2021 - of a number of FDA- approved FITs (including 1 FIT plus sDNA test). … Summary of Evidence by Key Question and Screening Test Test Name Study Design No. of Studies No. of … Summary of Evidence by Key Question and Screening Test (continued) Test Name Study Design No. of Studies … Vital signs: colorectal cancer screening test use: United States, 2012. … immunochemical fecal occult blood test than guaiac fecal occult blood test, despite lower compliance

19. Final Research Plan: Hepatitis B Virus Infection in Adolescents and Adults: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/hepatitis-b-virus-infection-screening
    March 14, 2019 - * “Chronic HBV infection” is defined by a positive HBsAg test result. … ‡ “Isolated anti-HBc positive” is defined as positive anti-HBc test results but negative anti-HBs … and HBsAg test results and indicates prior HBV exposure. … HBV vaccination is recommended for patients with positive isolated anti-HBc test results who are from … § “Never exposed to HBV” is defined as negative anti-HBs, anti-HBc, and HBsAg test results.

20. Recommendation: Colorectal Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening
    May 18, 2021 - ), fecal immunochemical test (FIT), and stool DNA test. … , and follow-up procedures for abnormal findings on a screening test. … during the procedure also varies by screening test. … https://medlineplus.gov/lab-tests/fecal-occult-blood-test-fobt/ 33. … ; gFOBT, guaiac fecal occult blood test; RCT, randomized clinical trial; sDNA-FIT, stool DNA test with