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1. Draft Research Plan: Screening for Colorectal Cancer | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/colorectal-cancer-screening3
   January 03, 2019 - ; FIT-DNA = fecal immunochemical test plus stool DNA test; FS = flexible sigmoidoscopy; gFOBT = guaiac-based … fecal occult blood test; m SEPT9 = methylated septin 9 gene DNA. … How are newer screening tests (e.g., fecal immunochemical test plus stool DNA test, computed tomography … ) Fecal immunochemical test plus stool DNA test (FIT-DNA) Blood-based test: Circulating methylated … septin 9 gene DNA test (m SEPT9 ) KQs 2, 3: Hemoccult II (review of test performance and harms

2. Draft Research Plan: Cervical Cancer: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/cervical-cancer-screening-adults-adolescents
   October 28, 2021 - What is the comparative effectiveness of different cervical cancer screening strategies (i.e., test … What is the test accuracy of and adherence to self-collected high-risk HPV vaginal samples? … Does the test accuracy or adherence vary by population (e.g., by age, gender, race and ethnicity, or … What are the comparative harms of different cervical cancer screening strategies (i.e., test, mode of … What is the comparative test accuracy of high-risk HPV tests used in U.S.

3. Final Research Plan: Colorectal Cancer: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/colorectal-cancer-screening
   May 16, 2019 - ; gFOBT=guaiac-based fecal occult blood test; m SEPT9 =methylated septin 9 gene DNA; sDNA test (+/- FIT … )= stool DNA test with or without FIT; SSP=sessile serrated polyp. … How are newer screening tests (e.g., stool DNA test with or without fecal immunochemical test, or computed … Fecal immunochemical test (quantitative and qualitative testing) Multitarget stool DNA test (with … DNA test (m SEPT9 ) * Urine-based test KQs 2, 3: New technologic enhancements to colonoscopy

4. Summary of USPSTF Draft Recommendation: Screening for Cervical Cancer (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/3UuREAobGvgLbE_FBAnrYQ
   January 13, 2025 - A Pap test is done with a swab of the cervix, usually at the same time as a pelvic exam. … This type of screening test needs to be done by a healthcare professional. … • Co-testing is a type of screening that combines an HPV test and a Pap test. … • Women ages 30–65 should ideally get an HPV test every 5 years. … Alternatively, they can get a Pap test every 3 years or co-testing test every 5 years.

5. Final Research Plan: Cervical Cancer: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cervical-cancer-screening-adults-adolescents
   March 17, 2022 - What is the comparative effectiveness of different cervical cancer screening strategies (i.e., test … What is the test accuracy of and adherence to self-collected high-risk HPV vaginal samples? … Does the test accuracy or adherence vary by population (e.g., by age, gender, race and ethnicity, or … What are the comparative harms of different cervical cancer screening strategies (i.e., test, mode of … What is the comparative test accuracy of high-risk HPV tests used in U.S.

6. Draft Research Plan: Vision in Children Ages 6 Months to 5 Years: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/vision-screening-children-ages-6-months-5-years
   April 24, 2025 - , including: visual acuity tests (e.g., autorefraction; picture identification tests, such as Allen test … ); and ocular alignment tests (e.g., corneal light reflex test, pupillary reflex test, cover-uncover … test, cross cover test, red reflex test) Studies assessing photoscreeners for screening will be included … risk factors, or refractive error (e.g., white reflex test) KQs 2, 3: Studies exclusively assessing … ), the comparison may be the same test administered at different timepoints or by a different person

7. Cervical Cancer Screening What You Should Know (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/YhwGborFkVokk_QjRwME9X
   December 03, 2024 - The type of screening test and how often you should be screened depends on factors including your … Age 20 and younger Do not get screened Age 21– 29 Get screened with a Pap test every 3 years … Age 30 –65 Get screened with an HPV test every 5 years Alternatively, get screened with: • A … Pap test every 3 years; or • A combination of Pap and HPV tests (co-testing) every 5 years Age 66 … and older Stop getting screened if you have had regular screenings with a history of normal test

8. Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-related Cancer in Women (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/qX9C7hyCBCNRjptQNCa_37
   December 01, 2013 - • Based on the results of genetic counseling, the woman may choose to have a genetic test. … The test involves examining her cells for changes in BRCA1 and BRCA2 genes. … • Because BRCA test results are complex, it is critical that the woman discuss her test results with … Based on the results of the BRCA test, the woman may choose a treatment that may reduce her chances of … • Others, after learning about the benefits and risks, decide not to have the genetic test.

9. Draft Research Plan: Syphilis Infection in Nonpregnant Adolescents and Adults: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/syphilis-infection-nonpregnant-adults-adolescents-1
   November 19, 2020 - What are the harms of screening (e.g., stigma, sequelae of test inaccuracy)? … are the benefits and tradeoffs of screening with reverse sequence testing (i.e., using a treponemal test … for initial screening followed by a nontreponemal test for confirmation) compared to the traditional … sequence testing algorithm (i.e., a nontreponemal test followed by a treponemal test)? … What is the clinical test performance of rapid point-of-care antibody tests?

10. Final Research Plan: Syphilis Infection in Nonpregnant Adolescents and Adults: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/syphilis-infection-nonpregnant-adults-adolescents-screening
    January 28, 2021 - What are the harms of screening (e.g., stigma, sequelae of test inaccuracy)? … are the benefits and tradeoffs of screening with reverse sequence testing (i.e., using a treponemal test … for initial screening followed by a nontreponemal test for confirmation) compared to the traditional … sequence testing algorithm (i.e., a nontreponemal test followed by a treponemal test)? … What is the clinical test performance of rapid point-of-care antibody tests?

11. Evidence Summary: Colorectal Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary19/colorectal-cancer-screening
    May 18, 2021 - compared with no screening; and (3) comparative trials of one screening test vs another screening test … For KQ2, the analyses primarily focused on per-person test accuracy of a single test application to detect … Serum Test Currently, one serum test—Epi proColon (Epigenomics)—is available to screen average-risk … In general test accuracy studies to clarify any differential in detection of proximal vs distal test … Screening test: Screening test was out of scope. Quality: Study was poor quality.

12. Screening for Colorectal Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/ocULFVqnfy4STqcU2DuPzU
    May 18, 2021 - compared with no screening; and (3) comparative trials of one screening test vs another screening test … For KQ2, the analyses primarily focused on per-person test ac- curacy of a single test application to … mSEPT9a Urine-based testb Metabolomic test Stool-based tests gFOBT sDNA test (with or without FIT … ; gFOBT, guaiac-based fecal occult blood test; mSEPT9, methylated septin 9 gene; sDNA test, stool DNA … Screening test: Screening test was out of scope. Quality: Study was poor quality.

13. Clinical Summary: Screening for Syphilis Infection in Pregnant Women (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/dwyoU5ur5oQM69fH8GoaSc
    August 28, 2018 - The traditional approach is to perform an initial “nontreponemal” antibody test (ie, Venereal Disease … Research Laboratory [VDRL] test or rapid plasma reagin [RPR] test), follow ed by a confirmatory “treponemal … ” antibody detection test (ie, f luorescent treponemal antibody absorption test or Treponema pallidum … particle agglutination test). … If the test results are discordant, a second treponemal test is performed.

14. Screening for Gestational Diabetes: Clinician Summary for USPSTF Recommendation (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/qPSAJPnBVmzFneXUDMRJfs
    August 01, 2021 - gestational diabetes by using 1 of several methods: • A 2-step process that involves a screening test … (oral glucose challenge test) followed by a diagnostic test (oral glucose tolerance test). … • A 1-step process where the diagnostic test (oral glucose tolerance test) is administered to all patients

15. Evaluating Test Strategies for Colorectal Cancer Screening: A Decision Analysis (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/UPu84CV2CNuxR8kpVU6e3V
    November 01, 2008 - Evaluating Test Strategies for Colorectal Cancer Screening: A Decision Analysis Evaluating Test Strategies … for that lesion and whether the lesion is within the reach of the test. … These variations re- sulted in 145 strategies: 90 single-test strategies, 54 com- bination-test strategies … of specificity and the sensitivity of the test for the present lesions. … for adenomas by size or for cancer and the reach of the test.

16. Screening for Colorectal Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/DYFdTVu-UY3h7CWGdA7Zkh
    July 20, 2021 - compared with no screening; and (3) comparative trials of one screening test vs another screening test … For KQ2, the analyses primarily focused on per-person test ac- curacy of a single test application to … Screening test: Screening test was out of scope. Quality: Study was poor quality. … Serum Test Currently, one serum test—Epi proColon (Epigenomics)—is avail- able to screen average-risk … In general test accuracy studies to clarify any differential in detection of proximal vs distal test

17. Screening for Colorectal Cancer Draft Recommendation Statement Frequently Asked Questions (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/hh22FmHmHLZbCGGG9A3kS9
    November 23, 2020 - For adults who are 45 to 75 years old, the harms of screening are small and vary by the screening test … How should a person decide which test to take? … follow-up testing, invasiveness, how often repeat screening is needed, and whether a test is performed … How often to repeat screening for colorectal cancer depends on which test a patient and their clinician … Test frequencies range from every year for the less invasive stool-based tests to every 5 to 10 years

18. Screening for Syphilis Infection in Nonpregnant Adolescents and Adults (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/tmpufJqkzbptG4uBtSGnam
    September 01, 2022 - (eg, Venereal Disease Research Laboratory [VDRL] or rapid plasma reagin [RPR] test). … If positive, confirm with a treponemal antibody detection test (eg, T pallidum particle agglutination … [TP-PA] test) … • Reverse sequence algorithm: Screen with an initial automated treponemal test (eg, enzyme-linked … If positive, confirm with a nontreponemal test.

19. Archived: Evaluating Test Strategies for Colorectal Cancer Screening: A Decision Analysis for the U.S. Preventive Services Task Force: Colorectal Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evaluating-test-strategies-for-colorectal-cancer-screening-a-decision-analysis-for-the-us-preventive-services-task-force/colorectal-cancer-screening-2008
    October 15, 2008 - to WhatsApp Share to Email Print archived Evaluating Test … for that lesion and whether the lesion is within the reach of the test. … These variations resulted in 145 strategies: 90 single-test strategies, 54 combination-test strategies … of specificity and the sensitivity of the test for the present lesions. … for adenomas by size or for cancer and the reach of the test.

20. Exercise Tolerance Testing To Screen for Coronary Heart Disease: A Systematic Review for the Technical Support for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/xbYLYNJZ5zJXj-W4DNyxyb
    June 20, 2019 - group: Normal exercise test result, 7.2/1000 person-years† Abnormal exercise test result, 1.5/1000 … result abnormal, 13 (416/3168) Both test results normal, 1.6% Either test result abnormal, 4.1% … : normal exercise test result, 0.5/1000 person-years†; abnormal exercise test result, 7.6/1000 person-years … Five-year follow-up of maximal treadmill stress test in asymptomatic men and women. … Accurate detection of coronary heart disease by new exercise test. Br Heart J. 1982;48:311-20.