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81. Kidney Tests | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/health-topics/kidney-tests/

82. Prenatal Testing | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/health-topics/prenatal-testing

83. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/musculoskeletal-complaints-tests-children_research-protocol.pdf
    September 29, 2010 - The rheumatoid factor (RF) test is the most commonly used serological test to determine the presence … A CCP test may also be ordered as a follow-up to a negative RF test when clinical signs, such as symmetrical … The ANA test is the primary screening test for SLE: an abnormal FANA titre with a homogeneous or speckled … represents a perfect test; an area of 0.5 represents a worthless test. … The strength of evidence for primary (diagnostic test performance) and secondary (test referrals, additional

84. An Empirical Assessment of Bivariate Methods for Meta-Analysis of Test Accuracy | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/bivariate-methods-utility/research
    November 19, 2012 - An Empirical Assessment of Bivariate Methods for Meta-Analysis of Test Accuracy Research Report November … Abstract Background Meta-analyses of sensitivity and specificity pairs reported from diagnostic test … employ a variety of statistical models for estimating mean performance and performance across different test … Results We reanalyzed 308 meta-analyses of test performance. … Alternative SROC curves provide useful global summaries of test performance.

85. Diagnosis and Treatment of Clinical Alzheimer's-type Dementia (CATD) | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/alzheimers-type-dementia/protocol
    November 27, 2018 - = Continuous Performance Test, CVLT = California Verbal Learning Test, DKEFS = Delis-Kaplan Executive … Information extracted only from diagnostic studies will include diagnostic test, reference test, and … , CSF, blood), within each diagnostic test category by specific test, and then by diagnostic accuracy … thresholds, reference test thresholds, and measures of test performance are comparable. … Please flag the test for the team if you are unsure if a test is validated or think that the measure

86. Diagnosis and Treatment of Clinical Alzheimer's-type Dementia (CATD) (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/catd-protocol-draft_0.pdf
    November 02, 2018 - Cognitive Tests to be Assessed for Diagnostic Accuracy Cognitive Test Categories Cognitive Test Names … Memory) Verbal memory Varies by test Confrontation naming (e.g., BNT) Language Varies by test … = Continuous Performance Test, CVLT = California Verbal Learning Test, DKEFS = Delis-Kaplan Executive … Information extracted only from diagnostic studies will include diagnostic test, reference test, and … thresholds, reference test thresholds, and measures of test performance are comparable.

87. 13-MDM347013 30..38 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/whitepaper4-bossuyt02262010-2.pdf
    January 01, 2009 - If so, they should be incorporated into test evaluation. … test results are all connected and can lead to changes in patients’ behavior. … symptoms or enable them to revise future life plans in light of their test results. … and followup, which may affect the net benefit of the test on health outcomes. … are clear for those who test positive and the downsides of treatment are known for those who test negative

88. 13-MDM347013 30..38 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/outcomes-testing-evaluation_research.pdf
    January 01, 2009 - If so, they should be incorporated into test evaluation. … test results are all connected and can lead to changes in patients’ behavior. … symptoms or enable them to revise future life plans in light of their test results. … and followup, which may affect the net benefit of the test on health outcomes. … are clear for those who test positive and the downsides of treatment are known for those who test negative

89. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
    November 22, 2011 - Which test (or combination of tests or no test) provides the best guide for whether a patient should … (modifying) predictive test performance, and the effectiveness of test-and-treatment strategies. … for small-study effects. 42 This test is often referred to as a test for publication bias; however … Genetic test: For the purpose of this review we will adopt the definition of a genetic test proposed … Phenotypic test: A phenotypic test is a means of evaluating the physiological characteristics of a

90. Musculoskeletal-Complaints-Tests-Children Surveillance (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/musculoskeletal-complaints-tests-children_surveillance.pdf
    January 08, 2013 - reported Sn of 100% for ANA test. … ) examined the prevalence of a positive IgM-RF test for pSLE. … patients who had an RF test and were seen at a children’s hospital. … ) examined the prevalence of a positive IgM-RF test for pSLE. … patients who had an RF test and were seen at a children’s hospital.

91. preoperative-testing-protocol-130514 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/preoperative-testing_research-protocol.pdf
    May 14, 2013 - • Aberrant test results may lead to cascade testing (either appropriate if the test result signals … To systematically review test performance would require a broader review of each test—beyond routine … We will not assess test results (i.e., abnormal vs. normal test results) as predictors of outcomes. … To  include  any   preoperative  test  evaluated  by  an  eligible  study.   … Effective strategy to guide pathology test ordering in surgical patients.

92. Key Question Tumor Cell-free DNA for Cancer Screening (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-key-question.pdf
    September 18, 2023 - .3 In 2013, researchers discovered a link between discordant findings from a non-invasive prenatal test … The implications for early cancer detection in asymptomatic patients were recognized by test developers … at average or high-risk for certain cancers and who are currently asymptomatic, a simple biomarker test … If passed into law, this would require CMS to cover an annual MCED test for all Medicare beneficiaries … Test developers are undertaking large clinical trials and partnering with health systems and research

93. Antinuclear Antibody, Rheumatoid Factor, and Cyclic-Citrullinated Peptide Tests for Evaluating Musculoskeletal Complaints in Children | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/musculoskeletal-complaints-tests-children/research
    March 07, 2012 - To explore differences in test performance for accuracy modifiers including age, sex, race or ethnicity … To evaluate the impact of test results on clinical decisionmaking and clinically important outcomes such … The 12 case-control studies that examined other test-disease combinations did not specifically address … The strength of evidence is insufficient to determine the test performance of ANA or CCP to diagnose … No studies examined clinically important outcomes such as the impact of the test results on referrals

94. PROPOSALS FOR A PHASED EVALUATION OF (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/whitepaper3-lijmer02262010-2.pdf
    January 01, 2009 - because of this test?” … Most models start with a Phase I, which consists of test development. … During this phase the test has to meet prespecified technical requirements. … establish how well the test is able to identify patients with the target condition. … How to evaluate a diagnostic marker test.

95. PROPOSALS FOR A PHASED EVALUATION OF (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-tests-proposals_research.pdf
    January 01, 2009 - because of this test?” … Most models start with a Phase I, which consists of test development. … During this phase the test has to meet prespecified technical requirements. … establish how well the test is able to identify patients with the target condition. … How to evaluate a diagnostic marker test.

96. genetic-testing-developmental-disabilities-protocol-140930 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/genetic-testing-developmental-disabilities_research-protocol.pdf
    September 30, 2014 - A genetic test may reach the market as a commercially distributed test kit approved or cleared by the … test kits include all reagents and instructions needed to complete the test procedure and interpret … Data Form for Each Test Identified Data Items Data Collected Data Source Test Describe the full name … The Landscape of Genetic Testing for Diagnosing DDs Clinical Test Available Test Provider/ Targeted … If a test has utility, it means that the results of the test can be used to seek effective treatment

97. Breast-Biopsy-Update Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
    September 01, 2014 - (e.g., blinding of index test assessors to reference standard results), reference standard test (e.g … Test Performance of Open Surgical Biopsy Published information on the test performance of open surgical … (i.e., a test without measurement error). … assessors to the index test results. … Test Performance and Comparative Test Performance Among women at average risk of cancer, core needle

98. Version-3-Immunity-After-Covid-19-Appendix-Table-B-1 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19-appendix-table-B-1.xlsx
    January 24, 2022 - N (%) Male Sex/Gender, N (%) Comorbidities, N (%) Assay Type Assay Brand Definition of a positive test … NR Vaccinated and unvaccinated adults with a positive RT-PCR test result before December 2, 2020. … Pts with initial positive test Mean: 50.5 (21.0) Pts with initial negative test Min: 52.8 (21.4) 237,210 … Ab+ at baseline with PCR+ during follow-up Positive serological test or PCR test upon recruitment PCR … Test type NR.

99. Cancer-Pancreas Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-pancreas_research-protocol.pdf
    August 09, 2013 - under which to order a second test and which test to order; and if a test is ordered, what is its influence … Test Criteria 1. … specificity of the test. … indicates that test A is more accurate, (2) evidence indicates that test B is more accuracy, or 3) … statistical test.

100. Comprehensive Overview of Methods and Reporting of Meta-Analyses of Test Accuracy | Effective Health Care Program
     effectivehealthcare.ahrq.gov/products/diagnostic-tests-reviews
     March 27, 2012 - Comprehensive Overview of Methods and Reporting of Meta-Analyses of Test Accuracy Timeline … Research Report Comprehensive Overview of Methods and Reporting of Meta-Analyses of Test