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381. Localized Prostate Cancer | Effective Health Care
     effectivehealthcare.ahrq.gov/decision-aids/prostate-cancer/12.html
     June 08, 2018 - Remember that if you choose active surveillance and you have a change in your test results, you can then

382. Quantitative Synthesis: Chapter 5. Network Meta-Analysis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-5.pdf
     February 01, 2018 - can be assessed using standard methods for evaluating homogeneity: ► I2 ► 𝝉𝝉𝟐𝟐 ► Cochran Q test … http://dx.doi.org/10.1016/j.jclinepi.2008.04.012 Single measures for consistency • Global Wald test … being easily interpreted. • Various approaches exist for comparing direct and indirect estimates: ► Z-test … ► Side-splitting Loop-based approaches • Z-test: Used to compare difference of pooled effect sizes … • Investigators should test relevant assumptions where possible, regardless of method chosen.

383. EHC Research Protocol: Management of Colonic Diverticulitis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diverticulitis-research-protocol.pdf
     January 01, 2019 - Specifically, (1) the systematic review will summarize existing systematic reviews on the test accuracy … What is the test accuracy of CT imaging for the diagnosis or staging of acute diverticulitis? … † Older studies are of little relevance to contemporary practice given changes in diagnostic test … For Key Question 1a (test accuracy), we will focus on test sensitivity and specificity for diagnosis … We expect that these will include: 17 • Test accuracy for o Diagnosing acute diverticulitis

384. Brooks_ECCS2012 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/brooks_eccs2012.pdf
     January 01, 2012 - Brooks_ECCS2012       Slide 1: Addressing  Tensions  When Conventional Wisdom, Clinical Practice   and  Evidence  Collide: Prostate Cancer Screening  Guidelines Durado  Brooks, M.D., M.P.H. Director, Prostate  and  Colorectal Cancers American Cancer…

385. Disposition of Comments for CER 153 Non-Muscle-Invasive Bladder Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/bladder-cancer-non-muscle-invasive_disposition-comments.pdf
     October 27, 2015 - --how often and how long should the interval use of cystoscopy be performed based on either pre-test … I believe that the most timely and useful information concerns the analysis of the test performance … probability…” Should this AHRQ report be able to spell out the pre-test probabilities? … related to the pre-test probability of a urothelial malignancy as AHRQ has done for the progression … Follow-up of the negative evaluation of microscopic hematuria related to pre-test probabilities 2.

386. Testing a Machine Learning Tool for Facilitating Living Systematic Reviews of Chronic Pain Treatments | Effective Health Care Program
     effectivehealthcare.ahrq.gov/products/machine-learning-tool
     November 03, 2020 - Testing a Machine Learning Tool for Facilitating Living Systematic Reviews of Chronic Pain Treatments Timeline October 30, 2020 Topic Initiated November 03, 2020 Research Report Testing a Machine Learning Tool for Facilitating Living Systematic Reviews of Ch…

387. Development and Usability Testing of EPC Evidence Review Dissemination Summaries for Health Systems Decisionmakers | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/usability-testing
     November 09, 2018 - Development and Usability Testing of EPC Evidence Review Dissemination Summaries for Health Systems Decisionmakers Timeline November 08, 2018 Topic Initiated November 09, 2018 Research Report Development and Usability Testing of EPC Evidence Review Dissemina…

388. FRN 35 - Preventive Pharmacological Treatments for Migraine in Adults: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-future_research.pdf
     April 01, 2013 - The most important multimodal treatments to test are those commonly used in practice and are likely … The most important drug combinations to test are those commonly used in practice or those suggested … Studies should be adequately powered to test hypothesized relationships, including among subgroups. … Resource use, size and duration High; large sample sizes to test differences among subgroups would … The most important multimodal treatments to test are those commonly used in practice and are likely

389. Impact of Contacting Study Authors on Systematic Review Conclusions: Diagnostic Tests for Hepatic Fibrosis | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/hepatic-fibrosis/white-paper
     April 02, 2014 - Impact of Contacting Study Authors on Systematic Review Conclusions: Diagnostic Tests for Hepatic Fibrosis White Paper April 2, 2014 Web Version [NLM Site] Download Main Document PDF 505.2 KB People using assistive technology may not be able to fully access information in these files. For additional ass…

390. Disposition of Comments Report for Imaging Techniques for the Diagnosis and Staging of Hepatocellular Carcinoma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_disposition-comments.pdf
     October 23, 2014 - The finding may be a reflection of the low pre test probability of HCC in the surveillance population … How does a negative ultrasound affect post-test probability? … Could use incidence rates of HCC in say HCV cirrhotics as pre-test probability. … pre- test probabilities of HCC. … The table is on test performance; the Zhang study does not report test performance (sensitivity/specificity

391. Localized Prostate Cancer | Effective Health Care
     effectivehealthcare.ahrq.gov/decision-aids/prostate-cancer/13.html
     June 08, 2018 - If you choose immediate treatment, or if you choose active surveillance and have a change in your test

392. Antibiotics-Respiratory-Infection Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_executive.pdf
     January 01, 2016 - CRP, white blood cell); rapid multiplex PCR tests used to rule in/out organisms (e.g., rapid strep test … C-Reactive Protein (CRP) Use of the CRP test has been shown to reduce overall prescribing for acute … For influenza testing, this finding was not surprising, as clinicians were likely using the test to … Moderate-strength evidence showed that the rapid strep test combined with a clinical score used as … Low- strength evidence also showed that the combination of a rapid strep test and a decision rule was

393. Antipsychotics for the Prevention and Treatment of Delirium: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/antipsychotics/research-protocol
     September 06, 2018 - prospective study of U.S. critically ill patients found that among 12-month survivors, ~25% had cognitive test … We will create standardized forms for data extraction and pilot test them. … analyses when there is higher heterogeneity. 24 Publication bias will be examined by using Begg's test … Operating characteristics of a rank correlation test for publication bias. … Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997 Sep 13;315(7109):629-34.

394. Diagnostic Errors in the Emergency Department: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/diagnostic-errors-emergency/protocol
     December 21, 2020 - We will create standardized forms for data extraction and pilot test them.  … -2) tool. 16 The QUADAS-2 tool assesses the risk of bias in four domains: patient selection, index test … analyses when there is higher heterogeneity. 19 Publication bias will be examined by using Begg's test … Operating characteristics of a rank correlation test for publication bias. … Bias in meta-analysis detected by a simple, graphical test.

395. Development and Implementation of Secure Statistical Analyses on Distributed Databases | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/dsitributed-database-analyses/abstract
     July 28, 2010 - As a result, this current project is to develop, test, and validate a method for secure statistical analysis

396. ASSESSING THE QUALITY OF INCLUDED STUDIES (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/assessing-the-risk-of-bias_draft-report.pdf
     June 02, 2011 - Pilot test and train Determine composition of the review team. … a health condition and typically compare results with those from another medical test. … We refer the reader to the AHRQ Medical Test Guidance). … for genetic test studies. … Systematic reviews of diagnostic test accuracy. Ann Intern Med. 2008 Dec 16;149(12):889-97. 21.

397. Gestational-Diabetes-Screening-Diagnosis Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gestational-diabetes-screening-diagnosis_executive.pdf
     October 01, 2012 - receive a subsequent diagnostic test.14 Typically, a 50 g oral glucose challenge test (OGCT) is initially … The domain of the index test was generally rated as low risk of bias (53 percent). … Limited data support the use of HbA1c as a screening test. … HbA1c does not perform as well as the 50 g OGCT as a screening test for GDM. … in favor of proceeding directly to a diagnostic test for GDM.

398. Antibody Response Following SARS-CoV-2 Infection and Implications for Immunity: Final Update of a Rapid, Living Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19.pdf
     December 31, 2022 - unvaccinated individuals, prior infection reduced the risk of hospitalization after a positive NAAT test … In our review, a central question is whether an antibody test obtained in everyday practice provides … A related but separate question is whether the test reliably confirms or excludes previous infection … Based on our updated results, it is highly likely that an antibody test specific for previous infection … if antibodies are present, the individual will have some protection at the time of the serological test

399. Technical Brief Summary - Impact of Community Health Worker Certification on Workforce and Service Delivery for Asthma and Other Selected Chronic Diseases (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/technical-brief-34-health-worker-certification-summary.pdf
     March 01, 2020 - Opportunities for additional research include: Conducting pragmatic randomized controlled trials to test … May keep out candidate CHWs with extensive experience in the community who are not good test-takers.

400. Comparative Effectiveness of Screening for Methicillin-Resistant Staphylococcus aureus (MRSA) | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/mrsa-screening-2010/research-protocol
     June 02, 2011 - Studies will be stratified by the turnaround time of the test used, rather than by the testing modality … Once the screening test results are received, patients who screen positive may be isolated; patients … Abbreviations: KQ = key question; MRSA = methicillin-resistant Staphylococcus aureus ; Test + = positive … MRSA-screening test result; Test – = negative MRSA-screening test result. … /estimation results) Test used Summary measures Sample variability measures Precision of estimate