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341. Renal-Function Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-function_executive.pdf
     August 01, 2014 - is dependent on the pre-test probability for suspected ACS (i.e., Bayes Theorem). … troponin is still low if the pre-test probability is low. … Conversely, low values do not exclude ACS if the pre- test probability is high. … Methods Guide for Medical Test Reviews. AHRQ Publication No. 12-EHC017. … Operating characteristics of a rank correlation test for publication bias.

342. Having a breast biopsy. A review of the research for women and thier families (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_consumer.pdf
     May 01, 2016 - Two common tests used to check for breast cancer are: � Mammogram (MAM-mo-gram): This test is a breast … This is considered the best screening test for breast cancer. … A biopsy is the only test that can tell for sure if a shadow or lump is breast cancer. … research is needed to know this for sure. 6 Note: Ask your doctor if you do not understand your test

343. A Primer for Systematic Reviewers on the Measurement of Functional Status and Health-Related Quality of Life in Older Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/quality-of-life-functional-status-measurement_white-paper.pdf
     September 01, 2013 - Test-retest reliability examines the agreement among scores in stable persons at two points in time. … There is no formal statistical test to evaluate content validity. … SEM is computed as the standard deviation at baseline times the square root of one minus test-retest … Test-retest reliability of health utilities index scores: evidence from hip fracture. … High degree of test- retest reliability among Dyspnea, Emotional function, and Mastery147 Test-Retest

344. Topic Suggestion Description | Effective Health Care Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/for-women-when-comparing-noninvasive-testingwhich-testing-method-echocardiography-mibi-spect-pharmacological-testing-etc-is-more-accurate-in-diagnosing-coronary-artery-disease-there-has-been-inadequate-studies-done-on-women-f
     April 10, 2009 - 113.5 KB] Briefly describe a specific question, or set of related questions, about a health care test

345. Calcineurin_Inhibitors_Protocol_FINAL_10-07-2014 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/calcineurin-inhibitor_research-protocol.pdf
     October 08, 2014 - below in separate categories pertaining to publication type, study design, patient characteristics, test … Addressing challenges in genetic test evaluation. … Methods guide for medical test reviews [AHRQ Publication No. 12-EHC017]. … of the test? … Internal validity and reporting adequacy: Has the reproducibility of the test when performed multiple

346. Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma Cell Dyscrasias | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/plasma-cell-dyscrasias-sflc-assay/research
     August 23, 2012 - Current Page Topic Timeline Jun. 17, 2009 Topic Suggestion May. 2, 2011 Research Protocol Aug. 23, 2012 Systematic Review Jun. 28, 2013 Disposition of Comments Report Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma Cell Dyscrasias Systematic Review Archived August 23, 2012 We…

347. Iron-Deficiency Anemia in Renal Dialysis Patients | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/iron-deficiency-anemia-in-renal-dialysis-patients
     June 17, 2008 - 132.9 KB] Briefly describe a specific question, or set of related questions, about a health care test

348. Topic Suggestion Description | Effective Health Care Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/description-of-a-question-or-questions-about-a-health-care-test-or-treatment-o-in-women-with-leiomyomas-who-are-candidates-for-surgery-does-the-use-of-adjunctive-medical-treatment-result-in-better-outcomes-preoperative-adjuva
     June 03, 2014 - 1.2 MB] Briefly describe a specific question, or set of related questions, about a health care test … Description of a question or questions about a health care test or treatment: In women with leiomyomas

349. Frameworks for Determining Research Gaps During Systematic Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-research-steps-framework_research.pdf
     June 01, 2011 - Pilot test of framework 6. Refinement and finalization of framework. … First, the average time taken to pilot test the framework was 3.5 hours per evidence report. … Our pilot test relied on applying the worksheet retrospectively on existing evidence reports. … They were often embedded in the test or implicit, however. … of Framework Selection of EPC Evidence Reports for Pilot Test Process for Pilot Test of Framework

350. Diagnosis and Treatment of Non-muscle Invasive Bladder Cancer | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/diagnosis-and-treatment-of-non-muscle-invasive-bladder-cancer
     October 03, 2012 - Cancer   Briefly describe a specific question, or set of related questions, about a health care test … The superiority of one test over another and the ideal clinical scenario for employing these tests remain

351. Interventions for Preventing Cognitive Decline, Mild Cognitive Impairment, and Alzheimer’s Disease | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/cognitive-decline/research-protocol
     March 23, 2016 - Consequently, short-term studies may be inadequate to test effectiveness of interventions to prevent … biomarker protein levels in a patient's blood or cerebrospinal fluid (CSF), or decline in cognitive test … volume Brain cell activity level As determined by: Blood/CSF tests, Validated cognitive test … volume Brain cell activity level As determined by: Blood/CSF tests, Validated cognitive test … For KQ2: To test the efficacy, comparative effectiveness, and harms of interventions to prevent, delay

352. Interventions To Improve Antibiotic Prescribing for Uncomplicated Acute Respiratory Tract Infections | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/antibiotics-respiratory-infection/clinician
     April 06, 2016 - Other point-of-care tests (such as the rapid strep test, multi-viral polymerase chain reaction [PCR] … The combination of a rapid strep test with a clinical score (FeverPAIN or a scale based on the presence … tests to rapidly determine the likelihood that a patient has a specific infection (e.g., rapid strep test … of a throat swab sample, multi-viral PCR or an influenza-specific test of throat/nasopharyngeal secretions

353. Supplemental Project To Assess the Transparency of Reporting Requirements: Tympanostomy Tubes in Children With Otitis Media (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research.pdf
     June 01, 2017 - Outcomes Study Outcomes NCT00365092 Auditory continuous performance test Child Behavior Checklist … Children’s version of the Hearing in Noise Test Comprehensive Test of Phonological Processing Disruptive … Child Behavior Checklist Children's Version of the Hearing in Noise Test Comprehensive Test of … Test–Revised Percentage of Consonants Correct–Revised Screening Test for Auditory Processing Disorders … Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997 Sep 13;315(7109):629-34.

354. AHRQ Slide Template 2009 (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/data-extraction.ppt
     January 01, 2009 - Pilot-test the forms on several published papers. … Use an iterative process and have several individuals test the form on multiple studies. … Characteristics of the Index Test and Reference Standard Characteristics of the Index Test and Reference … Here we get information on the characteristics of the index test and the reference standard, as well … as the criteria that test readers used.

355. Troponin Cardiac Marker Interpretation During Renal Function Impairment | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/renal-function/research-protocol
     June 13, 2013 - This may lead to misclassification and reduce the utility of the diagnostic test. … Publication bias will be examined by using Begg’s test 33 and Egger’s test 34 including evaluation … Methods Guide for Medical Test Reviews. AHRQ Publication No. 12-EC017. … Operating characteristics of a rank correlation test for publication bias. … Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997 Sep 13;315(7109):629-34.

356. Hypertension-Pulmonary-Arterial Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hypertension-pulmonary-arterial_research-protocol.pdf
     January 30, 2013 - An echocardiogram is a noninvasive test that provides an estimate of pulmonary artery pressures at rest … The test also helps to exclude valvular, primary myocardial, and congenital causes of Source: … (NT-proBNP) are two biological substances found in the blood that have been studied as a screening test … of PAH, biomarker testing may potentially identify patients with false- negative echocardiographic test … We will test for statistical heterogeneity using graphical displays and test statistics (Q and I2 statistics

357. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy_disposition-comments.pdf
     March 11, 2010 - Executive Summary Under study selection you say the reference test is intended to measure the “true” … is the most accurate test available? … It has been given in the footnote under the table, pre-test risk of 30%. … definition of sensitivity is always “in comparison to a reference test”. … You cannot calculate sensitivity without comparing the investigational test to a reference test.

358. Tool for Linking Evidence Reviews to Organizational Guideline Planning (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/linking-evidence-reviews-tools.pdf
     October 16, 2018 - Accompanies Methods Report: Linking Evidence Reviews to Organizational Guideline Planning: A Pilot Test

359. Simulation-Based Comparison of Methods for Meta-Analysis of Proportions and Rates | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/metanalysis-proportion-rate-comparison/research
     November 04, 2013 - example, researchers commonly perform meta-analyses of sensitivity and specificity to summarize medical test

360. Can anything be done to improve diabetic periphheral neuropathy?What is truly effective? What research seems promising? (diabetes type 2,well controlled) | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/can-anything-be-done-to-improve-diabetic-periphheral-neuropathywhat-is-truly-effective-what-research-seems-promising-diabetes-type-2well-controlled
     April 02, 2013 - 1.2 MB] Briefly describe a specific question, or set of related questions, about a health care test