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281. Schwitzer_ECCS2012 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/schwitzer_eccs2012.pdf
     July 23, 2012 - This excerpt comes from  an article, “Cancer Society Casts Doubt on Value of Prostate  Cancer Test … initially chose active surveillance after positive results from  a prostate-­‐specific  antigen  test … School of Medicine, tells his physician not to order a PSA   [prostate-­‐specific  antigen]  blood test … or an annual electrocardiogram  since neither test has  been  shown  to  save  lives …  posted  on its  blog: “…[O]ur greatest fear was that forces with an economic interest in the test

282. Effectiveness of Screening and Treatment of C. difficile Infections | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/c-diff-infections/research-protocol
     May 24, 2010 - for toxins if the first step test is positive. … Physicians may not always be sufficiently educated as to which diagnostic test is best to use and how … best to resolve a suspected false negative result (e.g., evidence suggests retesting with the same test … Outcomes for each question: Diagnostic Test Outcomes Sensitivity Specificity Predictive values … Timing: Diagnostic testing: time to test Antibiotic and non-standard treatments: variable, generally

283. - (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_appendixes.pdf
     January 01, 2009 - Sweat Test: A standard diagnostic test for cystic fibrosis that measures the concentration of chloride … Until death or Dec 1984 Student’s t test or Chi-square test and Cox proportional hazards model … Until death or Dec 1984 Student’s t test or Chi-square test and Cox proportional hazards model … Until death or transplant by July 1993 Student’s t test 6 minute walk test MD -101.7 m NS … NR Student’s t test 6 minute walk test MD -43 m (95%CI -53.23, 139.23) NR F-18

284. Prostate-Cancer-Therapies-Update Consumer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_consumer.pdf
     January 01, 2016 - � PSA blood test: This blood test tells how much PSA (a protein made by the prostate gland) is in … If the test results are not normal, your doctor may recommend more tests, such as a biopsy. … � T1: The cancer is too small to be felt during a digital rectal exam or seen in an imaging test … � T2: The cancer can be felt during a digital rectal exam and may be seen in an imaging test. … During checkups, your doctor may do a digital rectal exam, a PSA blood test, a biopsy, or other tests

285. Disposition of Comments Report for Imaging Tests for the Diagnosis and Staging of Pancreatic Adenocarcinoma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_disposition-comments.pdf
     September 23, 2014 - The report acknowledges that CT is usually the first test. … We did not want to assume that the typical test is also the best test. … the literature to support test strategies. … We note that the accuracy of any given imaging test could not be determined, since studies did not … provide results separately for each screening test.

286. Linking Evidence Reviews to Organizational Guideline Planning | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/linking-evidence
     October 18, 2018 - Research Report Linking Evidence Reviews to Organizational Guideline Planning: A Pilot Test

287. Chapter 8: Meta-Analysis of Test Performance When There Is a “Gold Standard” | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/methods-guidance-tests-metaanalysis/methods/

288. Topic 0613 Tympanostomy Tubes NSD FINAL (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0765-150129.pdf
     November 03, 2014 - Questions from Nominator: Key Question #3: What is the comparative effectiveness of obtaining a hearing test … years, being considered for tympanostomy tubes Intervention(s): Hearing testing Comparator(s): No test … Should clinicians obtain a hearing test prior to inserting tympanostomy tubes? 3.

289. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0012_03-21-2008.pdf
     January 01, 2008 - What is the yield of screening with a TSH test? … Since the prevalence of high and low TSH test Subclinical Hypothyroidism Nomination Summary Document

290. Renal-Function Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-function_research-protocol.pdf
     June 13, 2013 - This may lead to misclassification and reduce the utility of the diagnostic test. … Publication bias will be examined by using Begg’s test and Egger’s test, including evaluation of the … Methods Guide for Medical Test Reviews. Rockville, MD. 2010. … Operating characteristics of a rank correlation test for publication bias. … kidney-disease-test-protocol.2 kidney-disease-test-protocol.3 kidney-disease-test-protocol.4 kidney-disease-test-protocol

291. Effective Health Care Program
     effectivehealthcare.ahrq.gov/health-topics/lupus-0
     March 07, 2012 - Antinuclear Antibody, Rheumatoid Factor, and Cyclic-Citrullinated Peptide Tests for Evaluating Musculoskeletal Complaints in Children Systematic Review Archived March 7, 2012 Antinuclear Antibody, Rheumatoid Factor, and Cyclic-Citrullinated Peptide Testing for the Evaluation of Musculoskeletal Co…

292. Towards a Framework for Communicating Confidence in Methodological Recommendations for Systematic Reviews and Meta-Analyses (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methodological-recommendations-framework-communications_research.pdf
     September 01, 2013 - The original paper emphasized that this test was valid in the equal effect setting. … Chapter 8: meta-analysis of test performance when there is a "gold standard". … Comprehensive Overview of Methods and Reporting of Meta-Analyses of Test Accuracy. … Arcsine test for publication bias in meta- analyses with binary outcomes. … Diagnostic test accuracy working group: Handbook for diagnostic test accuracy reviews. 2011; http:

293. C-Diff-Infections-Surveillance-140925 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections-surveillance-140925.pdf
     January 01, 2014 - to have used clinical stool specimen, compared at least two diagnostic tests, and used a reference test … Rapid and sensitive loop-mediated isothermal amplification test for Clostridium difficile detection … challenges cytotoxin B cell test and culture as gold standard. … test used. … difficile, the illumigene C. difficile test and the Xpert C.

294. Topic Suggestion Description | Effective Health Care Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/treatment-of-epilepsy
     March 10, 2008 - 101.8 KB] Briefly describe a specific question, or set of related questions, about a health care test

295. Topic Suggestion Description | Effective Health Care Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/sleep-apnea-diagnosis
     May 13, 2008 - 135.2 KB] Briefly describe a specific question, or set of related questions, about a health care test

296. Disposition of Comments for CER 158 Diagnosis of Gout (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout-diagnosis-disposition-160727.pdf
     February 24, 2016 - Regarding the circularity of KQ1b, the test whose accuracy was of primary interest (or at least how … the accuracy of the test was affected by number and identity of affected joints) was synovial fluid … Even if these test well so far I am concerned. … The population of interest is those to whom the diagnostic test would be applied to - this includes … This obviously influences the reported sensitivity of the test.

297. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0334_08-04-2010.pdf
     January 01, 2010 - lead to improvements in health outcomes compared to a no-testing strategy, and in whether the genetic test … comparison of testing strategies, there exist several treatment options that may be selected based on the test

298. Instrumental Variable Methods in Comparative Safety and Effectiveness Research | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/instrumental-variable-methods/research
     May 14, 2010 - These tests assume that one has available a valid IV and the test then attempts to determine whether … F(1,63051)=12.30 P-val=0.0005 Anderson-Rubin Wald test Chi-sq(1)=12.30 P-val=0.0005 Stock-Wright LM … (Cragg-Donald Wald F statistic): 1.5e+04 Stock-Yogo weak ID test critical values: 10% maximal IV size … F(1,63045)=19.74 P-val=0.0000 Anderson-Rubin Wald test Chi-sq(1)=19.74 P-val=0.0000 Stock-Wright LM … (Cragg-Donald Wald F statistic): 1.5e+04 Stock-Yogo weak ID test critical values: 10% maximal IV size

299. An analytical framework for quantifying components of variability in prescriber decisions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/instrumental-variable-methods_research.pdf
     April 01, 2010 - These tests assume that one has available a valid IV and the test then attempts to determine whether … F(1,63051)=12.30 P-val=0.0005 Anderson-Rubin Wald test Chi-sq(1)=12.30 P-val=0.0005 … (Cragg-Donald Wald F statistic): 1.5e+04 Stock-Yogo weak ID test critical values: 10% … F(1,63045)=19.74 P-val=0.0000 Anderson-Rubin Wald test Chi-sq(1)=19.74 P-val=0.0000 … (Cragg-Donald Wald F statistic): 1.5e+04 Stock-Yogo weak ID test critical values: 10%

300. Disposition of Comments Report for Core Needle and Open Surgical Biopsy for Diagnosis of Breast Lesions: An Update to the 2009 Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_disposition-comments.pdf
     September 10, 2014 - Why did this report shift to analysis of comparative test performance? … We believe that the evidence on each test of interest is of moderate strength. … We have provided additional information on the definition of all diagnostic test result categories. … Results Page 43: Wait time for test results. … The Authors mention a study that used "a microwave processor to reduce wait times for test results