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261. Topic Suggestion Description | Effective Health Care Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/key-questions-1-does-routine-preoperative-testing-compared-to-no-testing-or-alternative-testing-strategies-improve-outcomes-such-as-surgical-complications-other-morbidity-and-mortality-among-patients-undergoing-elective-surge
     February 10, 2011 - 128.7 KB] Briefly describe a specific question, or set of related questions, about a health care test … potassium in patients on diuretics, pregnancy test in women of child-bearing age) Do routine preoperative … time/partial promboplastin time basic or complete metabolic panel, urinalysis, and urine pregnancy test … variation in preoperative testing, decrease costs, maximize quality, improve physician confidence with test

262. Topic 0586 LUTS Secondary to BPH NSD FINAL (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0713-140625.pdf
     January 07, 2014 - interested in the adverse effects of pharmacotherapy treatment options, and patient characteristics or test … effects of pharmacotherapy treatment options; a better understanding of the patient characteristics or test … What are the patient characteristics or test results that can be used to determine the optimal pharmacotherapy

263. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-executive.pdf
     December 01, 2009 - Studies of diagnostic test performance compare the results of the experimental test to a reference test … The reference test is intended to measure the “true” disease status of each patient. … Studies of diagnostic test performance were examined to see if they met the inclusion criteria. … In general, the smaller the negative likelihood ratio, the more accurate 4 the diagnostic test is … However, each individual woman’s post-test risk varies by her individual pre-test risk of malignancy.

264. Skin Conditions | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/health-topics/skin-conditions
     December 08, 2017 - Treatments for Basal Cell and Squamous Cell Carcinoma of the Skin Systematic Review December 8, 2017 Technical Brief: Evaluation of Suspicious Skin Lesions Using Non-Invasive Diagnostic Techniques Research Protocol Archived August 23, 2010 Systematic Review of Treatments f…

265. Hepatic-Fibrosis White-Paper (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatic-fibrosis_white-paper.pdf
     April 01, 2014 - No test for which we obtained additional data was originally rated low strength of evidence. … No test for which we obtained additional data was originally rated low strength of evidence, where … Comparison of test performance profile for blood tests of liver fibrosis in chronic hepatitis C. … How to use an article about a diagnostic test. B. … Genet Test Mol Biomarkers. 2012 Jun;16(6):531-5. PMID: 22352690. 63.

266. Disposition of Comments Report for Serum Free Light Chain Analysis for the Diagnosis, Management, and Prognosis of Plasma-Cell Dyscrasias (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_disposition-comments.pdf
     August 23, 2012 - This conundrum exemplifies the challenges surrounding evaluation of a test in monoclonal disorders. … This was done to allow for a comparison of test accuracy among patients that were not preselected as … “Hospital stays” may be an unrealistic outcome to measure for a laboratory test (would performing a … Site as a future light chain test for evaluation. … Finally, it is the most useful test in patients with amyloidosis.

267. Breast Diseases | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/health-topics/breast-diseases
     February 13, 2012 - Noninvasive Diagnostic Tests for Breast Abnormalities: Update of a 2006 Review Systematic Review Archived February 13, 2012 Effectiveness of Noninvasive Diagnostic Tests for Breast Abnormalities Systematic Review Archived February 9, 2006 Data Points #14: Use of endocrine t…

268. Screening for Glaucoma: Comparative Effectiveness | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/glaucoma-screening/research
     April 12, 2012 - For diagnostic test accuracy, we included case control studies, designs in which tests were performed … on all participants, and designs in which participants were randomized to one test.

269. Reporting the Findings of Updated Systematic Reviews of Comparative Effectiveness: How Do Users Want To View New Information? | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/reporting-findings-updated-reviews/white-paper
     May 16, 2013 - To test the five differently formatted summaries, we identified several categories of users of CERs, … by several organizations whose role is to conduct systematic reviews and updates and to create and test

270. Health Facilities | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/health-topics/health-facilities
     November 15, 2011 - Archived October 29, 2010 Using the Principles of Randomized Controlled Trial Design to Guide Test

271. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0332_07-29-2010.pdf
     January 01, 2010 - active treatment) lead to improvements in health outcomes compared to a no-testing strategy, or are test … Errors in test assay leading to inaccurate results. b. … This test is already being marketed and there is a critical need for an understanding of how this marker

272. Treating Localized Prostate Cancer | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/prostate-cancer-therapies-update/consumer
     January 21, 2016 - PSA blood test: This blood test tells how much PSA (a protein made by the prostate gland) is in your … If the test results are not normal, your doctor may recommend more tests, such as a biopsy. … T1 : The cancer is too small to be felt during a digital rectal exam or seen in an imaging test (such … T2 : The cancer can be felt during a digital rectal exam and may be seen in an imaging test. … During checkups, your doctor may do a digital rectal exam, a PSA blood test, a biopsy, or other tests

273. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0411_02-10-2011.pdf
     January 01, 2011 - time/partial thromboplastin time, basic or complete metabolic panel, urinalysis, and urine pregnancy test … (e.g., potassium in patients on diuretics, pregnancy test in women of child-bearing age) 4.

274. Comparative Effectiveness Research Review Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_disposition-comments.pdf
     February 13, 2012 - We did calculate the positive likelihood ratios and used those to illustrate post-test probability of … disease across a range of pre-test probabilities. … Non- invasive test such as MRI have unknown long term risk of Gd exposure and PET, BSGI and MIBI have … Analytical framework schema (page 27) indicates the non-invasive diagnostic test would occur after … If an available non-invasive diagnostic test could assist clinicians in evaluating women....

275. Disposition of Comments for Imaging Tests for the Staging of Colorectal Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_disposition-comments.pdf
     November 20, 2014 - Estimates of test performance should incorporate information from all sources. … and the other imaging test in the same patients. … So the test of choice is heavily dependent on the clinical situation. … accuracy Our own report was restricted to test accuracy studies that examined comparative test performance … All of these studies used PET/CT, compared test accuracy of PET/CT vs.

276. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections_executive.pdf
     December 01, 2011 - Direct comparisons of diagnostic tests without a reference test were not included. … We included initial cure, recurrence (variably defined by symptoms with or without a positive test for … Otherwise, there was only low-strength evidence for or against differences in test specificities. … There was moderate evidence that the test specificities in one comparison did not differ. … Bayes’ formula, then the differences in post-test probabilities might not lead to different clinical

277. Evidence gaps for mHealth tools in diabetes | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/evidence-gaps-for-mhealth-tools-in-diabetes
     May 10, 2016 - 234 KB] Briefly describe a specific question, or set of related questions, about a health care test

278. Hypertension-Pulmonary-Arterial Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_executive.pdf
     April 01, 2013 - structure and function of the right heart in patients with pulmonary hypertension.7 However, this test … Therefore, although transthoracic echocardiography is the standard screening test for PAH, it is less … NT-proBNP) are two biological substances found in the blood that have been studied as a screening test … Thirty-four studies used RHC as a reference test, 15 studies used 6MWD as a reference test, and 10 … studies used FC as a reference test.

279. Using the Principles of Randomized Controlled Trial Design to Guide Test Evaluation | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/rtc-design-principles/research

280. Renal-Cancer Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_research-protocol.pdf
     April 20, 2015 - Risk: Low/High/Unclear Domain 2: Index Test(s) (complete for each index test used) Were the index … test results interpreted without knowledge of the reference standard? … Methods to detect publication bias for medical test studies are not robust. … Chapter 8: meta-analysis of test performance when there is a "gold standard". … Methods Guide for Medical Test Reviews.