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241. Disposition of Comments Report for Biomarkers for Assessing and Managing Iron Deficiency Anemia in Late-Stage Chronic Kidney Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-kidney-disease-anemia-2011_disposition-comments.pdf
     January 01, 2011 - Key Question 4 addresses the factors that may affect test performance and clinical utility of newer … How we graded the strength of evidence for the test performance of reticulocyte hemoglobin content ( … Also, just because a test reduces the likelihood of iron administration and can save cost (naturally … RPA recommends the report be very clear about whether any diagnostic test is to be used to predict … It is believed that % HYPO may not an adequate test if samples cannot be delivered to a central lab

242. Infectious Disease Including HIV/AIDS #09 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/infectiousdisease_hi_impact.pdf
     December 01, 2013 - The test is intended to simultaneously detect the presence of M. … The test is available in the U.S. as a research-use-only reagent; U.S. marketing approval of a test … results (e.g., tuberculin skin test, QuantiFERON-TB Gold test), and/or chest x-ray results. 138,139 … the sample simultaneously with a nucleic acid amplification test, an acid-fast bacteria smear test … $50 per test).

243. Localized Prostate Cancer | Effective Health Care
     effectivehealthcare.ahrq.gov/decision-aids/prostate-cancer/11.html
     June 08, 2018 - If your test results change, you can then choose to begin a treatment to remove or destroy your cancer … If there is a change in your test results, your doctor will talk to you about whether it is time to begin

244. Technical Brief 13: Gene Expression Profiling for Predicting Outcomes in Stage II Colon Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_technical-brief.pdf
     December 01, 2012 - • What is the test turn-around time, that is, how long does it take to obtain test results? … Turnaround Time, That is, how Long Does it Take To Obtain Test Results? … The potential adverse effects from use of the test are also considered. … Test accuracy (clinical validity, analytic validity) 2. Impact of test on management? 3. … Adverse events of test - directed treatment? 5.

245. Infectious Disease Including HIV/AIDS #09 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/09_infectiousdisease_potential_high_impact_june_2012.pdf
     January 01, 2012 - The test is available in the U.S. as a research-use-only reagent; U.S. marketing approval of a test … results (e.g., tuberculin skin test, QuantiFERON-TB Gold test), and/or chest x-ray results. 173,174 … the sample simultaneously with a nucleic acid amplification test, an acid-fast bacteria smear test … $50 per test). … The only on-demand, rapid Mycobacterium tuberculosis test.

246. Chapter 1: Introduction to the Methods Guide for Medical Test Reviews | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/methods-guidance-tests-introduction/methods/

247. Chapter 6: Assessing Applicability of Medical Test Studies in Systematic Reviews | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/methods-guidance-tests-applicability/methods/

248. Wireless Motility Capsule Versus Other Diagnostic Technologies for Evaluating Gastroparesis and Constipation: A Comparative Effectiveness Review | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/wireless-motility-capsule/research-protocol
     March 14, 2012 - However, the test has been validated and in use since the late 1960s. 8 Colonic Scintigraphy Colon … For this test, the manometry catheter is placed with endoscopic and fluoroscopic guidance after a full … Some experts thought that it would likely be a complementary test rather than an independent test for … Interventions The test of interest is the wireless motility capsule testing, alone (KQs 1 and 3) or … Methods Guide for Medical Test Reviews.

249. Is Lung Cancer Screening Right for Me? A decision aid for people considering lung cancer screening with low-dose computed tomography. (pdf file)
     effectivehealthcare.ahrq.gov/decision-aids/lung-cancer-screening/static/lung-cancer-screening-decision-aid.pdf
     March 01, 2016 - , 18 will have an invasive procedure such as a biopsy (a tiny piece of lung tissue is removed to test … If you have a positive screening test, but your followup imaging tests and biopsy do not show cancer … Diagnostic testing is done when someone has signs or symptoms of lung cancer or when a screening test … If the screening test is positive, additional testing may involve higher doses of radiation. … Having other tests if you have a positive screening test?

250. Is Lung Cancer Screening Right for Me? A decision aid for people considering lung cancer screening with low-dose computed tomography. (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/lung-cancer-screening-decision-aid.pdf
     March 01, 2016 - , 18 will have an invasive procedure such as a biopsy (a tiny piece of lung tissue is removed to test … If you have a positive screening test, but your followup imaging tests and biopsy do not show cancer … Diagnostic testing is done when someone has signs or symptoms of lung cancer or when a screening test … If the screening test is positive, additional testing may involve higher doses of radiation. … Having other tests if you have a positive screening test?

251. Celiac-Disease Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/celiac-disease_executive.pdf
     January 01, 2016 - This test is less useful in IgA-deficient individuals. DGP antibodies. … • All participants underwent both the “index test” and the reference standard (biopsy). … for EmA IgA • Test for tTG IgA • Test for DGP IgA antibodies • EmA IgG, tTG IgG, and DGP IgG tests … with an EmA or DGP test. … Methods Guide for Medical Test Reviews. AHRQ Publication No. 12-EC017.

252. Disposition of Comments Report for Noninvasive Technologies for the Diagnosis of Coronary Artery Disease in Women (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_disposition-comments.pdf
     June 12, 2012 - CONCLUSIONS: A multicomponent CMR stress test can accurately diagnose CAD in women. … It is unclear what anatomic differences affect stress test results; and g. … which may influence these test parameters. … I assume this differs by test method. … However, it was unclear from the tables how the test performed in the reference subgroup.

253. Mechanistic Evidence in Evidence-Based Medicine: A Conceptual Framework | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/mechanistic-evidence-framework/white-paper
     June 19, 2013 - The objective was to identify and pilot test a framework for the evaluation of the evidential weight … with technical experts, (4) Refinement of framework, (5) Development of two case studies, (6) Pilot test

254. Cad-Women-Diagnosis Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_executive.pdf
     June 01, 2012 - More than one NIT test is often required when the initial test results are equivocal. … Systematic reviews of diagnostic test accuracy. Ann Intern Med 2008;149(12):889-97. … Regression methods for meta-analysis of diagnostic test data. … Methods Guide for Medical Test Reviews [posted November 2010]. Rockville, MD. … The Accuracy of the Electrocardiogram during Exercise Stress Test Based on Heart Size.

255. Disposition of Comments for Efficacy and Safety of Screening for Postpartum Depression (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-postpartum-screening_disposition-comments.pdf
     May 01, 2013 - Performance” or “Diagnostic Test Characterisitic”. … test performance and the resources required to perform the test. … Conceptually, a more resource-intensive test might be preferable to a self-administered test if the … test performance and the resources required to perform the test. … Conceptually, a more resource- intensive test might be preferable to a self- administered test if the

256. Ch 3-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_3-user-guide-to-ocer_130129.pdf
     September 21, 2012 - A test for interaction is conducted to evaluate if a subgroup variable has a statistically significant … Even though the interaction test has low power to detect a true difference in subgroup effects, there … The interaction test will be statistically significant (at a significance level of 0.05), on average … It should also be noted that a statistical test of interaction does not correspond to an assessment … If the interaction test is not significant: - Report ATE.

257. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0310_05-13-2008.pdf
     January 01, 2008 - What are the best available screening and diagnostic tests (e.g., test characteristics vs. costs; e.g … What is the evidence on utilizing only the clinical criteria to omit a screening test and perform a

258. Laboratory Biomarkers for Iron Deficiency Anemia in Late Stage Chronic Kidney Disease | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/chronic-kidney-disease-anemia-2011/research-protocol
     August 29, 2011 - Different forms of iron-deficiency anemia could affect the diagnostic test performance of iron-status … What reference standards are used for the diagnosis of iron status in studies evaluating test accuracy … Adverse effects or harms associated with testing and associated treatments (e.g., test-related anxiety … the diagnostic test performance and the effectiveness of test-oriented treatments (KQ 4). … We will test the forms on several studies and revise as necessary before full data extraction. D.

259. Heart-Failure-Natriuretic-Peptide Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_executive.pdf
     November 01, 2013 - Test Performance and Optimal Decision Cutpoints. … Determinants Affecting Test Performance. … Test Performance and Optimal Cutpoints. … Determinants Affecting Test Performance. … This should provide users of the test with robust information on the applicability of the test to patients

260. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia-2011_research-protocol.pdf
     January 01, 2011 - Different forms of iron-deficiency anemia could affect the diagnostic test performance of iron-status … What reference standards are used for the diagnosis of iron status in studies evaluating test accuracy … Question 4 What factors affect the test performance and clinical utility of newer markers of iron … affecting the diagnostic test performance and the effectiveness of test-oriented treatments (KQ 4) … We will test the forms on several studies and revise as necessary before full data extraction.