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181. Schwitzer_ECCS2012 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/schwitzer_eccs2012.pdf
     July 23, 2012 - This excerpt comes from  an article, “Cancer Society Casts Doubt on Value of Prostate  Cancer Test … initially chose active surveillance after positive results from  a prostate-­‐specific  antigen  test … School of Medicine, tells his physician not to order a PSA   [prostate-­‐specific  antigen]  blood test … or an annual electrocardiogram  since neither test has  been  shown  to  save  lives …  posted  on its  blog: “…[O]ur greatest fear was that forces with an economic interest in the test

182. Renal-Function Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-function_research-protocol.pdf
     June 13, 2013 - This may lead to misclassification and reduce the utility of the diagnostic test. … Publication bias will be examined by using Begg’s test and Egger’s test, including evaluation of the … Methods Guide for Medical Test Reviews. Rockville, MD. 2010. … Operating characteristics of a rank correlation test for publication bias. … kidney-disease-test-protocol.2 kidney-disease-test-protocol.3 kidney-disease-test-protocol.4 kidney-disease-test-protocol

183. Towards a Framework for Communicating Confidence in Methodological Recommendations for Systematic Reviews and Meta-Analyses (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methodological-recommendations-framework-communications_research.pdf
     September 01, 2013 - The original paper emphasized that this test was valid in the equal effect setting. … Chapter 8: meta-analysis of test performance when there is a "gold standard". … Comprehensive Overview of Methods and Reporting of Meta-Analyses of Test Accuracy. … Arcsine test for publication bias in meta- analyses with binary outcomes. … Diagnostic test accuracy working group: Handbook for diagnostic test accuracy reviews. 2011; http:

184. C-Diff-Infections-Surveillance-140925 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/c-diff-infections-surveillance-140925.pdf
     January 01, 2014 - to have used clinical stool specimen, compared at least two diagnostic tests, and used a reference test … Rapid and sensitive loop-mediated isothermal amplification test for Clostridium difficile detection … challenges cytotoxin B cell test and culture as gold standard. … test used. … difficile, the illumigene C. difficile test and the Xpert C.

185. Disposition of Comments for CER 158 Diagnosis of Gout (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout-diagnosis-disposition-160727.pdf
     February 24, 2016 - Regarding the circularity of KQ1b, the test whose accuracy was of primary interest (or at least how … the accuracy of the test was affected by number and identity of affected joints) was synovial fluid … Even if these test well so far I am concerned. … The population of interest is those to whom the diagnostic test would be applied to - this includes … This obviously influences the reported sensitivity of the test.

186. Topic 0613 Tympanostomy Tubes NSD FINAL (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0765-150129.pdf
     November 03, 2014 - Questions from Nominator: Key Question #3: What is the comparative effectiveness of obtaining a hearing test … years, being considered for tympanostomy tubes Intervention(s): Hearing testing Comparator(s): No test … Should clinicians obtain a hearing test prior to inserting tympanostomy tubes? 3.

187. An analytical framework for quantifying components of variability in prescriber decisions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/instrumental-variable-methods_research.pdf
     April 01, 2010 - These tests assume that one has available a valid IV and the test then attempts to determine whether … F(1,63051)=12.30 P-val=0.0005 Anderson-Rubin Wald test Chi-sq(1)=12.30 P-val=0.0005 … (Cragg-Donald Wald F statistic): 1.5e+04 Stock-Yogo weak ID test critical values: 10% … F(1,63045)=19.74 P-val=0.0000 Anderson-Rubin Wald test Chi-sq(1)=19.74 P-val=0.0000 … (Cragg-Donald Wald F statistic): 1.5e+04 Stock-Yogo weak ID test critical values: 10%

188. Disposition of Comments Report for Core Needle and Open Surgical Biopsy for Diagnosis of Breast Lesions: An Update to the 2009 Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_disposition-comments.pdf
     September 10, 2014 - Why did this report shift to analysis of comparative test performance? … We believe that the evidence on each test of interest is of moderate strength. … We have provided additional information on the definition of all diagnostic test result categories. … Results Page 43: Wait time for test results. … The Authors mention a study that used "a microwave processor to reduce wait times for test results

189. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0012_03-21-2008.pdf
     January 01, 2008 - What is the yield of screening with a TSH test? … Since the prevalence of high and low TSH test Subclinical Hypothyroidism Nomination Summary Document

190. For women, when comparing noninvasive testing,which testing method (echocardiography, MIBI-SPECT, pharmacological testing, etc.) is more accurate in diagnosing coronary artery disease. There has been inadequate studies done on women for… | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/get-involved/nominated-topics/for-women-when-comparing-noninvasive-testingwhich-testing-method-echocardiography-mibi-spect-pharmacological-testing-etc-is-more-accurate-in-diagnosing-coronary-artery-disease-there-has-been-inadequate-studies-done-on-women-

191. Choosing the Important Outcomes for a Systematic Review of a Medical Test | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/methods-guidance-tests-outcomes/slides

192. Meta-analysis of Test Performance Evidence When There is a “Gold Standard” | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/methods-guidance-tests-metaanalysis/slides

193. Version 2_Risk of Reinfection From SARS-CoV-2 -- An Update of an Antibody Response Following SARS-CoV-2 Infection and Implications for Immunity: A Living Rapid Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-2-risk-of-reinfection-from-SARSCoV2_0.pdf
     December 31, 2022 - Nine studies used antibody test results to assign patients to the “positive” or “negative” cohorts;23 … , 26, 28, 30, 31, 33, 37-39 three used a combination of antibody test results and PCR;9, 29, 36 and … 13 days after the initial positive PCR test.14 A large proportion of patients in the dataset … This finding applies only to people who have had a negative antibody test (e.g., for surveillance in … Association of SARS-CoV-2 Seropositive Antibody Test With Risk of Future Infection.

194. S89 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s89.pdf
     October 01, 2007 - In the current study of MCV, we specified an alpha of 0.05 for a 1-sided test. … †One-sided test; when relative risk �1, the log likelihood ratio was set to 0. … †One-sided test; when relative risk �1, the log likelihood ratio was set to 0. … A maximized sequential probability ratio test for vaccine and drug safety surveillance. … A maximized sequential probability ratio test for drug and vaccine adverse event surveillance.

195. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
     May 24, 2010 - for toxins if the first step test is positive. … Physicians may not always be sufficiently educated as to which diagnostic test is best to use and how … best to resolve a suspected false negative result (e.g., evidence suggests retesting with the same test … • Outcomes for each question: Diagnostic Test Outcomes 1. Sensitivity 2. Specificity 3. … • Timing: Diagnostic testing: time to test http://www.effectivehealthcare.ahrq.gov/�

196. Gout Executive-2016 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive-2016.pdf
     January 01, 2016 - However, if no such studies could be identified for a diagnostic test of interest, studies were also … Patient-level factors that influence test behavior have also been understudied. … Assessing risk of bias as a domain of quality in medical test studies. … In: Methods Guide for Medical Test Reviews. AHRQ Publication No. 12-EHC017. … Methods Guide for Medical Test Reviews. AHRQ Publication No. 12-EHC017.

197. Disposition of Comments for Use of Natriuretic Peptide Measurement in the Management of Heart Failure (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_disposition-comments.pdf
     November 20, 2013 - General In point of fact, this document may wish to make the comment that like no other diagnostic test … Simply adding another test because it has excellent rule out diagnostic accuracy does not make sense … But is ruling out the purpose the test is used for? … What will happen to test positive patients and test negative patients? … The length of follow up was unrestricted – there was not limit on how long after the index test the

198. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0334_08-04-2010.pdf
     January 01, 2010 - lead to improvements in health outcomes compared to a no-testing strategy, and in whether the genetic test … comparison of testing strategies, there exist several treatment options that may be selected based on the test

199. Disposition of Comments for PCA3 Testing for the Diagnosis and Management of Prostate Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-test_disposition-comments.pdf
     April 01, 2013 - Even though this test is not invasive, it is a reasonable point that it does require manipulation; … In order to facilitate a comparison of a new test associated with managing patients with a potential … PR # 8 Results Your results do not necessarily support the FDA approved indication for this test. … the massage, this test may have acceptability concerns to patients. … PR # 12 Discussion/ Conclusions This test is clearly not a major improvement over PSA.

200. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tethered-spinal-cord-protocol.pdf
     July 19, 2023 - Surgical detethering, other surgeries, physical therapy, bracing Final health outcomes: KQ1: Test … : The index test domain evaluates whether the conduct or interpretation of the test could have introduced … bias, taking into account whether the results of the test were interpreted without knowledge of the … results were interpreted without knowledge of the results or index test … • Directness: Describes whether the intervention (test, treatment, or strategy) and the comparator