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121. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/gestational-diabetes-screening-diagnosis_research-protocol.pdf
     December 16, 2011 - receive a subsequent diagnostic test. 1,8 Typically, a 50 g oral glucose challenge screening test … A hierarchical regression approach to meta-analysis of diagnostic test accuracy evaluations. … Operating characteristics of a rank correlation test for publication bias. … Bias in meta-analysis detected by a single graphical test. Br Med J 1997;315:629–34. 30. … Glucose Tolerance Test/ 16. Glucose Intolerance/ 17.

122. Methods Research Report: Testing a Machine Learning Tool for Facilitating Living Systematic Reviews of Chronic Pain Treatments (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-testing-machine-learning-tool-chronic-pain.pdf
     November 01, 2020 - Publication No. 21-EHC004 November 2020 ii Key Messages Purpose of Project To develop and test … text word-only search strategies without MEDLINE® indexing for three chronic pain living reviews, test … This project had three stages: develop optimized search strategies (Stage 1), test machine learning … machine learning classifier on optimized searches (Stage 2), and test machine learning classifier on … and to test the performance of a machine classifier on the optimized search strategies.

123. FRN 41 - Noninvasive Technologies for the Diagnosis of Coronary Artery Disease in Women: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis-future_research_1.pdf
     February 01, 2013 - '/exp AND 'exercise test'/exp OR exercise AND test) OR treadmill) OR ('echocardiography'/exp OR echo … '/exp AND 'exercise test'/exp OR exercise AND test) OR treadmill AND ('single photon emission computer … '/exp AND 'exercise test'/exp OR exercise AND test) OR treadmill AND (cardio* OR heart OR coronary OR … '/exp AND 'exercise test'/exp OR exercise AND test) OR treadmill AND (cardio* OR heart OR coronary OR … '/exp AND 'exercise test'/exp OR exercise AND test) OR treadmill)) OR ('single photon emission computer

124. Disposition of Comments for Technical Brief 23 Genetic Testing (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/genetic-testing-developmental-disabilities_disposition-comments.pdf
     June 30, 2015 - However, we would include any study that compare a test of interest with a nongenetic test. … In the tables in Appendix D, we reported information on “Genetic Counseling Required Pre-Test or Post-Test … So, these 56 tests are not one same test. … A clinical test is either an FDA-cleared/approved commercial kit or a laboratory-developed test (LDT … , it is the diagnostic test.

125. Evidence Summary-Comparative-Effectiveness-Review-213-Lower-Limb-Prostheses (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-213-lower-limb-protheses-evidence-summary.pdf
     September 01, 2018 - The instruments evaluated are: • 1 Leg Standing Balance • 180 Degree Turn Test • 2MWT (2 Minute Walk … Test) • 6MWT (6 Minute Walk Test) • AAS (Amputee Activity Survey) • ABC (Activities-specific Balance … ) • Functional Reach Test • Houghton Scale • L Test (L Test of Functional Mobility) • LCI (Locomotor … Capabilities Index) • LEMOCOT (Lower-Extremity Motor Coordination Test) • NQ-ACGC (Quality of Life … (31%) to predict falls, but this test overall was not statistically significant (P=0.22).

126. Breast-Abnormalities-Tests-Update Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_executive.pdf
     February 01, 2012 - Sensitivity is a measure of how accurately the test can identify women with cancer; specificity is a … measure of how accurately the test can identify women who do not have cancer. … test with high specificity will rarely misclassify women without cancer as having cancer. … This estimate is known as a “pre-test” or “prior” probability. … if an additional imaging test will be helpful in guiding management decisions.

127. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
     September 08, 2011 - Whether or not the semi-quantitative test will yield similar results to the quantitative test is unknown … o Was the reference standard independent of the index test (i.e. the index test did not form part of … o Was the execution of the index test described in sufficient detail to permit replication of the test … the test is used in practice? … o Were uninterpretable/intermediate test results reported?

128. Infectious Disease Including HIV/AIDS #09 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1412.pdf
     December 22, 2014 - ................................................................................ 10 Xpert MTB/RIF Test … test that is run on Cepheid’s GeneXpert® real-time polymerase chain reaction (PCR) system. … The test is intended to simultaneously detect M. tuberculosis complex species and determine whether … results (e.g., tuberculin skin test, QuantiFERON-TB Gold test), and/or chest radiographs.108,109 The … the sample simultaneously with a nucleic acid amplification test, an acid- fast bacteria smear test

129. Glaucoma-Screening Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_executive.pdf
     April 01, 2012 - SAP Suprathreshold Test Evidence From Burr et al., 2007. … SAP Threshold Test Evidence From Burr et al., 2007. … Based on analyses of the common criterion for each test, test accuracy, combination tests, tests for … standard if the candidate test was one of function or a test of function as the reference if the … candidate test were one of structure.

130. Colorectal-Cancer-Staging Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_executive.pdf
     September 01, 2014 - T2-weighted MRI) Outcomes: • Test performance outcomes – Test performance (sensitivity, specificity … Single test performance. … performance for a particular imaging test. 3. … Comparative test performance. … Methods Guide for Medical Test Reviews. AHRQ Publication No. 12-EHC017.

131. Gout Dx protocol_140715-draft (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_research-protocol-2014.pdf
     January 01, 2014 - What are the adverse effects associated with each diagnostic test (including pain, infection at the … Assessing Risk of Bias as a Domain of Quality in Medical Test Studies. … Methods Guide for Medical Test Reviews. Rockville (MD); 2012. 14. … Operating characteristics of a rank correlation test for publication bias. … Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997 Sep 13;315(7109):629-34.

132. Santa_ECCS2012 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/santa_eccs2012.pdf
     February 01, 2013 - • The most common screening test was an electrocardiogram, followed by a stress  test and  ultrasound … 2) • 11 percent had  talked  with  their  physician  about followup if the  screenin test … • 9 percent  had discussed the accuracy of the test. … • 4 percent knew about the potential complications from  the test. … • 1 percent had  discussed  with  their  physician  whether  or not the  test saved

133. Executive Summary CER 171: Noninvasive Testing for Coronary Artery Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/coronary-artery-disease-testing_executive.pdf
     March 01, 2011 - test-negative people. … Moreover, the impact of a negative test or the treatment downstream from a positive test may extend … pathways were followed after the initial test, which test(s) may lead to the most appropriate treatment … Studies did not provide information on the impact of test results on post-test risk stratification … Documentation of management of those who test positive compared with those who test negative and followup

134. Breast-Abnormalities-Tests-Update Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-abnormalities-tests-update_research-protocol.pdf
     July 01, 2010 - that affected the accuracy of the noninvasive test being evaluated. … ” because the outcome of test accuracy is indirectly related to health outcomes. … Meta-DiSc: a software for meta- analysis of test accuracy data. … Sensitivity: the proportion of women with breast cancer who test positive for breast cancer. … Specificity: the proportion of women with benign lesions who test negative for breast cancer.

135. Topic 0451 Celiac Disease NSD FINAL (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-533_05-24-2013.pdf
     January 01, 2013 - nominator is a celiac disease (CD) patient interested in finding out about “easier Summary: ways” to test … Staff-Generated PICO Population(s): Patients with suspected CD with a positive serology test Intervention … (s): Alternative confirmatory test strategies including additional serologic testing, HLA typing and … avoidance of the potential harms associated with biopsy Key Questions Is there an “easier way” to test

136. Prostate-Cancer-Risk-Assessment-Genes Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-risk-assessment-genes_executive.pdf
     July 01, 2012 - pre-analytic or analytic variables)43 Clinical validity A measurement of the accuracy with which a test … predictive value Clinical utility Degree to which benefits are provided by positive and negative test … The commercial availability of a test panel was defined as a clinical test offered (or soon to be offered … ) by a certified laboratory, or licensed or certified kit reagent test panels sold for use by clinical … What are the sources of variation in accuracy or analytical validity across different test platforms

137. Using the Principles of Randomized Controlled Trial Design to Guide Test Evaluation | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/rtc-design-principles/research

138. Blood Count Tests | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/health-topics/blood-count-tests

139. PCA3 Testing in the Diagnosis and Management of Prostate Cancer: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-antigen-3-gene_research.pdf
     April 01, 2013 - Highest priority went to establishing the diagnostic accuracy of the test. … Hence, the value of such a test would obviously be limited. … accuracy alone would not necessarily equate to test effectiveness. … The value of such a test would obviously be limited. … Lack of information on how demographics impact PCA3 test. 5.

140. Disposition of Comments for CER 171 Noninvasive Testing for Coronary Artery Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/coronary-artery-disease-testing_disposition-comments.pdf
     March 29, 2016 - TEP 2 Introduction p.11 - again, CACS should be removed since it is a screening test quite different … Really well done, especially the differentiation by pre- test risk groups and by site of testing. … A negative stress test would provoke further evaluation for other etiologies of the chest pain. … But only the pre-test risks reported by authors of the studies were used for stratification. … Classification of patient pre-test risk was based on how it was described in the studies.