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101. An Empirical Assessment of Bivariate Methods for Meta-Analysis of Test Accuracy | Effective Health Care Program
     effectivehealthcare.ahrq.gov/products/bivariate-methods-utility
     November 19, 2012 - An Empirical Assessment of Bivariate Methods for Meta-Analysis of Test Accuracy Timeline … Research Report An Empirical Assessment of Bivariate Methods for Meta-Analysis of Test

102. Using the Principles of Randomized Controlled Trial Design to Guide Test Evaluation | Effective Health Care Program
     effectivehealthcare.ahrq.gov/products/rtc-design-principles
     November 09, 2009 - Using the Principles of Randomized Controlled Trial Design to Guide Test Evaluation Timeline … Research Report Using the Principles of Randomized Controlled Trial Design to Guide Test

103. Evaluating Practices and Developing Tools for Comparative Effectiveness Reviews of Diagnostic Test Accuracy: Methods for the Joint Meta-Analysis of Multiple Tests | Effective Health Care Program
     effectivehealthcare.ahrq.gov/products/diagnostic-tests-accuracy
     January 16, 2013 - Evaluating Practices and Developing Tools for Comparative Effectiveness Reviews of Diagnostic Test Accuracy … Evaluating Practices and Developing Tools for Comparative Effectiveness Reviews of Diagnostic Test

104. Addressing Challenges in Genetic Test Evaluation: Evaluation Frameworks and Assessment of Analytic Validity | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/genetic-tests-validity-rating-evaluation
     June 16, 2011 - Addressing Challenges in Genetic Test Evaluation: Evaluation Frameworks and Assessment of Analytic Validity … June 16, 2011 Research Report Addressing Challenges in Genetic Test

105. Noninvasive Testing for Coronary Artery Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-disease-testing_research-protocol.pdf
     January 15, 2015 - The first step is assessing pre-test likelihood that the patient has CAD. … for test-positive people. … Harms related to both the initial test as well as subsequent testing will be evaluated. … Methods Guide for Medical Test Reviews. AHRQ Publication No. 12-EC017. … positive and are treated with those who test negative and are not treated.

106. Imaging for Pretreatment Staging of Small Cell Lung Cancer | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/lung-cancer-staging/research-protocol
     December 08, 2014 - Test criteria Type of test. … or test strategy compared to another test or test strategy. … or test strategy compared to another test or test strategy. … or test strategy compared to another test or test strategy. … /test strategy compared to another test or test strategy.

107. Biomarkers for Assessing and Managing Iron Deficiency Anemia in Late-Stage Chronic Kidney Disease | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/chronic-kidney-disease-anemia-2011/research
     October 12, 2012 - The remaining 12 studies investigated the test performance of newer or classical markers of iron status … There is also a low level of evidence that sTfR has a similar test performance compared with classical … iron treatment, but the strength of evidence was insufficient to come to a conclusion regarding the test … For Key Question 4 (factors affecting the test performance and clinical utility of newer markers), we … Furthermore, we can conclude that there is insufficient evidence to determine the test performance of

108. Imaging Tests for the Diagnosis and Staging of Pancreatic Adenocarcinoma | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/cancer-pancreas/research-protocol
     August 09, 2013 - under which to order a second test and which test to order; and if a test is ordered, what is its influence … specificity of the test. … test. … It is computed by dividing the number of patients who test positive on the imaging test by the number … It is computed by dividing the number of patients who test negative on the imaging test by the number

109. Biomarkers for Assessing and Managing Iron Deficiency Anemia in Late-Stage Chronic Kidney Disease: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia_research.pdf
     January 01, 2013 - results, and differences in test performance pose a dilemma regarding the most appropriate test to … results, and differences in test performance pose a dilemma regarding the most appropriate test to … Low / Insufficient (depending on the test comparisons, study populations, or test performance … For example, to evaluate the test performance of a diagnostic test, it is ideal to recruit consecutive … In contrast, to evaluate the test performance of a monitoring test, it is ideal to recruit consecutive

110. Blood-based Tests for Multiple Cancer Screening: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-protocol.pdf
     June 05, 2024 - KQ 3: Studies that provide data related to test accuracy; both prediagnostic test performance and diagnostic … test performance designs are eligible. … Methods guide for medical test reviews. … Radio Multicancer detection test accuracy Single-cancer detection test accuracy Other Study … cancer and negative test) N False Positives (participants without cancer and positive test)

111. Appedixes A-D (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-911-workforce-appendixes_0.pdf
     December 10, 2021 - 206 n with event: 2 (1%) Newberry, 202110 Age, 18-34 Incidence PCR test SARS-COV2 206 n with event … : 2 (1%) Newberry, 202110 Age, 35-49 Prevalence IgG seroprevalence test SARS-COV2 556 n with event: … SARS-COV2 594 n with event: 8 (1%) Newberry, 202110 Race, White Incidence PCR test SARS-COV2 594 n … SARS-COV2 26 n with event: 0 (0%) Newberry, 202110 Race, Asian Prevalence IgG seroprevalence test … SARS-COV2 78 n with event: 0 (0%) Newberry, 202110 Race, Other Prevalence IgG seroprevalence test

112. Cancer-Pancreas Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
     September 01, 2014 - Test Criteria a. Type of test. … one of the following three types of conclusions: (1) test A is more accurate than test B, (2) test B … ) may permit more estimates of single test staging accuracy. … Specific test protocols, however, may differ between the studies we included and the typical test parameters … 17 (e.g., for staging small tumors, one test is best, but for large tumors, another test is best

113. Liver-Cancer Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer_research-protocol.pdf
     July 24, 2013 - What is the comparative test performance of imaging techniques for diagnosing HCC? i. … What is the comparative test performance of imaging techniques on diagnostic thinking? c. … and the reference standard, and use preset criteria to define a positive test. … Methods Guide for Medical Test Reviews. AHRQ Publication No. 12-EHC017-EF. … Methods Guide for Medical Test Reviews. AHRQ Publication No.12- EHC017-EF.

114. Protocol: Imaging for Pretreatment Staging of Small Cell Lung Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-staging_research-protocol.pdf
     December 08, 2014 - Test criteria a. Type of test. … or test strategy compared to another test or test strategy … or test strategy compared to another test or test strategy … or test strategy compared to another test or test strategy … /test strategy compared to another test or test strategy

115. Routine Preoperative Testing: Comparative Effectiveness Review | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/preoperative-testing/research-protocol
     May 14, 2013 - Aberrant test results may lead to cascade testing (either appropriate if the test result signals a real … To systematically review test performance would require a broader review of each test--beyond routine … We will not assesses test results (i.e., abnormal vs. normal test results) as predictors of outcomes. … To include any preoperative test evaluated by an eligible study. … Effective strategy to guide pathology test ordering in surgical patients.

116. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pregnancy_hi_impact.pdf
     January 01, 2012 - Endoglin urine test for preeclampsia screening 5. … application for a test kit. … test (LDT) to be performed on samples sent to its Sequenom Center for Molecular Medicine. … blood test). 47 This test appears to be closest to product launch and was expected to launch in fall … Many experts suggested that the MaterniT21 test has the potential for controversy.

117. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0488_12-27-2011.pdf
     January 01, 2011 - outcomes (related to accurate diagnosis leading to immediate appropriate management or false negative test … mortality (related to accurate diagnosis leading to immediate appropriate management or false negative test … results resulting in delayed appropriate management)  Harms and costs related to false positive test … Which imaging test or test that can “see” some functions of a cancer (e.g., blood flow, consumption … of sugar, etc.) is the best test to diagnose pancreatic cancer and tell how advanced it is or how widely

118. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/12_pregnancy_potential_high_impact_june_2012.pdf
     January 01, 2012 - (San Diego, CA), which markets a laboratory-developed test and is in the process of developing a test … (Redwood City, CA) developed a test (the verifi™ Non- Invasive Prenatal Test) that is also based on … The test that is furthest along in development is Sequenom, Inc.’s (San Diego, CA) MaterniT21™ test … Sequenom developed the MaterniT21 test, a DNA-based, first-trimester screening assay (blood test) using … http://www.verinata.com/news/non-invasive-prenatal-test/ http://www.verinata.com/news/non-invasive-prenatal-test

119. Localized Prostate Cancer | Effective Health Care
     effectivehealthcare.ahrq.gov/decision-aids/prostate-cancer/05.html
     June 08, 2018 - men that choose screening, two tests that may be used to detect prostate cancer are: PSA blood test … : A blood test that detects a protein, called prostate-specific antigen (PSA), made by the prostate … This test shows how much PSA is in your blood. … If your PSA levels are higher than normal or have increased over time, your doctor might test you for

120. Imaging Techniques for the Diagnosis and Staging of Hepatocellular Carcinoma | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/liver-cancer/research
     October 23, 2014 - The purpose of this review is to compare the effectiveness of imaging techniques for HCC on test performance … tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET) that evaluated test … the reference standard used and study, patient, tumor, and technical characteristics on estimates of test … A total of 281 studies were included, 274 of which evaluated test performance. … Although there are some potential differences in test performance between different imaging modalities