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81. Imaging Tests for the Diagnosis and Staging of Pancreatic Adenocarcinoma | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/cancer-pancreas/research-protocol
    January 01, 2020 - under which to order a second test and which test to order; and if a test is ordered, what is its influence … specificity of the test. … test. … It is computed by dividing the number of patients who test positive on the imaging test by the number … It is computed by dividing the number of patients who test negative on the imaging test by the number

82. PowerPoint Presentation (ppt file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/medical-test-reviews-genetic.ppt
    June 01, 2012 - Methods guide for medical test reviews. … Methods guide for medical test reviews. … Methods guide for medical test reviews. … Methods guide for medical test reviews. … of a genetic test result.

83. Blood-based Tests for Multiple Cancer Screening: A Systematic Review (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cell-free-dna-draft-report.pdf
    December 01, 2024 - For KQ 3 (test accuracy), we extracted author reported accuracy data for each test, cancer type, or … This test, a precursor to the test currently under development called Cancerguard (Exact Sciences), … Yet, there is potential for test developers to revise estimates of test accuracy using different lengths … Test pricing and billing. 2024. https://www.galleri.com/patient/the- galleri-test/cost. … https://www.galleri.com/patient/the-galleri-test/cost https://www.galleri.com/patient/the-galleri-test

84. What is the most effective therapy for a depressed patient who has not responded to an SSRI? | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/what-is-the-most-effective-therapy-for-a-depressed-patient-who-has-not-responded-to-an-ssri
    November 01, 2017 - Your Nomination - Please briefly describe in your own words the question about a health care test or … problem have considerable health or financial hardships   There is uncertainty about how well the test … new technology/development   There is new evidence of clinical and/or cost effectiveness for this test … What is the specific purpose of the health care test or treatment you have a question about? … risk assessment for a disease   Risks or harms that can come from a disease identification tool or test

85. Evaluating Practices and Developing Tools for Comparative Effectiveness Reviews of Diagnostic Test Accuracy: Methods for the Joint Meta-Analysis of Multiple Tests | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/diagnostic-tests-accuracy/research
    November 01, 2017 - Evaluating Practices and Developing Tools for Comparative Effectiveness Reviews of Diagnostic Test … Evaluating Practices and Developing Tools for Comparative Effectiveness Reviews of Diagnostic Test … Structured Abstract Background Existing methods for meta-analysis of diagnostic test accuracy focus … primarily on a single index test rather than comparing two or more tests that have been applied to the … rates (TPR, sensitivity) and between the false-positive rates (FPR, one minus specificity) of each test

86. Searching for Studies (ppt file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/medical-test-reviews-search-strategies.ppt
    June 01, 2012 - Test Review This figure presents an overview of the steps in the medical test review process. … Methods guide for medical test reviews. … Methods guide for medical test reviews. … There also may be test overlap, in which case the test name alone may be insufficient. … As an example, think of the hematocrit test, also known as packed cell volume test.

87. Appendicitis Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/appendicitis_executive.pdf
    December 01, 2015 - When five or more sufficiently similar studies evaluated the test performance of the same test in the … Studies of Test Performance In general, studies of test performance were deemed to be at moderate to … Test Performance of Clinical Symptoms and Signs (in Isolation) Table A presents key test performance … Test Performance of Laboratory Tests (in Isolation) Table B presents key test performance results for … Summary estimates of test performance of diagnostic imaging for acute appendicitis Test Population

88. Musculoskeletal-Complaints-Tests-Children Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/musculoskeletal-complaints-tests-children_executive.pdf
    March 01, 2012 - Clinical Impacts of Test Results In children and adolescents aged 18 years or less with undiagnosed … presented forest plots to summarize the results for each test–disease pairing. … ) examined the prevalence of a positive IgM-RF test for pSLE. … pediatric patients who had an RF test and were seen at a children’s hospital. … A result of high Sp and low Sn was observed for almost all the test–disease combinations.

89. Imaging for Pretreatment Staging of Small Cell Lung Cancer | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/lung-cancer-staging/research-protocol
    December 01, 2019 - Test criteria Type of test. … or test strategy compared to another test or test strategy. … or test strategy compared to another test or test strategy. … or test strategy compared to another test or test strategy. … /test strategy compared to another test or test strategy.

90. Genetic Testing | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/health-topics/genetic-testing
    June 30, 2015 - For some, it is important to know whether a disease can be prevented or treated if a test is positive … But test results might help a person make life decisions, such as family planning or insurance coverage … Presentation September 1, 2013 Training Modules for the Methods Guide for Medical Test … Methods Guide – Chapter June 1, 2012 Chapter 6: Assessing Applicability of Medical Test … Average Risk Adults Research Report June 16, 2011 Addressing Challenges in Genetic Test

91. Decision-Analytic Modeling to Evaluate Benefits and Harms of Medical Tests – Uses and Limitations | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/benefits-harms-modeling/research
    November 01, 2017 - High test performance does not guarantee that physicians will act according to test results, that patients … Different Roles A medical test can have different roles in a test-and-treat strategy, depending on … Different versions of a test can have very different performance characteristics. … Designing studies to ensure that estimates of test accuracy are transferable. … Regression methods for meta-analysis of diagnostic test data.

92. PowerPoint Presentation (ppt file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/medical-test-reviews-genetic.ppt
    June 01, 2012 - Methods guide for medical test reviews. … Methods guide for medical test reviews. … Methods guide for medical test reviews. … Methods guide for medical test reviews. … of a genetic test result.

93. Imaging Techniques for the Surveillance, Diagnosis, and Staging of Hepatocellular Carcinoma | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/liver-cancer/research-protocol
    December 01, 2019 - What is the comparative test performance of imaging techniques for diagnosing HCC? … What is the comparative test performance of imaging techniques on diagnostic thinking? … and the reference standard, and use preset criteria to define a positive test. … Methods Guide for Medical Test Reviews. AHRQ Publication No. 12-EHC017-EF. … Methods Guide for Medical Test Reviews. AHRQ Publication No.12-EHC017-EF.

94. Laboratory Tests | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/health-topics/laboratory-tests
    November 27, 2018 - A technician or your doctor analyzes the test samples to see if your results fall within the normal range … Many factors affect test results. … Your sex, age and race What you eat and drink Medicines you take How well you followed pre-test

95. My nomination is about comparing outcomes of different glaucoma treatments, particularly canaloplasty to trabeculectomy and to medical therapy alone. | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/my-nomination-is-about-comparing-outcomes-of-different-glaucoma-treatments-particularly-canaloplasty-to-trabeculectomy-and-to-medical-therapy-alone
    November 01, 2017 - Your Nomination - Please briefly describe in your own words the question about a health care test or … problem have considerable health or financial hardships   There is uncertainty about how well the test … treatment, or intervention works   There is significant potential for side effects/harms using this test … new technology/development   There is new evidence of clinical and/or cost effectiveness for this test … What is the specific purpose of the health care test or treatment you have a question about?

96. Blood-based Tests for Multiple Cancer Screening: A Systematic Review | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/cell-free-dna/draft-report
    January 01, 2025 - Screening for multiple cancers in a single blood test may offer a potentially transformative approach … accuracy designs conducted in external validation populations for outcomes related to test accuracy … Fifteen studies (N=91,514) reported 64 estimates of  test accuracy for 14 MCSTs (28 unique comparisons … The evidence was insufficient to assess the harms of diagnostic evaluation after a positive test: one … Accuracy of MCSTs varied by test and study design.

97. COPD is common and respiratory failure due to COPD is an increasingly common disorder. Use of non-invasive positive pressure ventilation (NPPV) for patients with respiratory failure due to exacerbatons of COPD. Several trials and… | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/copd-is-common-and-respiratory-failure-due-to-copd-is-an-increasingly-common-disorder-use-of-non-invasive-positive-pressure-ventilation-nppv-for-patients-with-respiratory-failure-due-to-exacerbatons-of-copd-several-trials-an
    November 01, 2017 - Your Nomination - Please briefly describe in your own words the question about a health care test or … problem have considerable health or financial hardships   There is uncertainty about how well the test … new technology/development   There is new evidence of clinical and/or cost effectiveness for this test … What is the specific purpose of the health care test or treatment you have a question about? … risk assessment for a disease   Risks or harms that can come from a disease identification tool or test

98. Chronic-Kidney-Disease-Anemia-2011 Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/chronic-kidney-disease-anemia-2011_executive.pdf
    January 01, 2011 - • Overall test accuracy: Overall accuracy of a test is expressed as area under the ROC curve (AUC) … • Test accuracy: Test accuracy refers to sensitivity (true positive rate) and specificity (true negative … rate) of a test. … ability or test agreement). … Low/ Insufficient (depending on the test comparisons, study populations, or test performance

99. Layout 1 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests_executive.pdf
    February 01, 2006 - the risk that she has cancer even if the test is negative. … Notes: Sensitivity is the probability that a test is positive in those with the disease. … Specificity is the probability that a test is negative in those without the disease. … inevitably affects the specificity of the test. … to the test, it is used to calculate the risk of having the disease despite a negative test result.

100. More information is needed on the long-term effects of antipsychotic therapy in older adults. Please consider new research in the benefits and harms of treating patients with atypical antipsychotics. | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/more-information-is-needed-on-the-long-term-effects-of-antipsychotic-therapy-in-older-adults-please-consider-new-research-in-the-benefits-and-harms-of-treating-patients-with-atypical-antipsychotics
     November 01, 2017 - Your Nomination - Please briefly describe in your own words the question about a health care test or … problem have considerable health or financial hardships   There is uncertainty about how well the test … new technology/development   There is new evidence of clinical and/or cost effectiveness for this test … What is the specific purpose of the health care test or treatment you have a question about? … risk assessment for a disease   Risks or harms that can come from a disease identification tool or test