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61. Medical Tests - White Paper Series | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/medical-tests-series/overview
    August 01, 2019 - published in Medical Decision Making and served as background papers for the Methods Guide for Medical Test … (EPCs), other experts in government, industry, and academia and also marked the launch of a Medical Test … Group was charged with developing guidance for conducting comparative effectiveness reviews of medical test … Using the Principles of Randomized Controlled Trial Design to Guide Test Evaluation . … Using the Principles of Randomized Controlled Trial Design to Guide Test Evaluation .

62. PowerPoint Presentation (ppt file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/medical-test-reviews-options-summarizing.ppt
    June 01, 2012 - Methods guide for medical test reviews. … “Truly” Diseased “Truly” Healthy RS (+) RS (-) RS (+) RS (-) Index test (+) 1 2 2 1 Index test … (-) 1 2 2 1 RS (+) RS (-) Index test (+)  = 1 + 2  = 1 + 2 Index test (-)  = 1 + … Comparison of a screening test and a reference test in epidemiologic studies. II. … Comparison of a screening test and a reference test in epidemiologic studies. II.

63. PowerPoint Presentation (ppt file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/medical-test-reviews-options-summarizing.ppt
    June 01, 2012 - Methods guide for medical test reviews. … “Truly” Diseased “Truly” Healthy RS (+) RS (-) RS (+) RS (-) Index test (+) 1 2 2 1 Index test … (-) 1 2 2 1 RS (+) RS (-) Index test (+)  = 1 + 2  = 1 + 2 Index test (-)  = 1 + … Comparison of a screening test and a reference test in epidemiologic studies. II. … Comparison of a screening test and a reference test in epidemiologic studies. II.

64. Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/antiplatelet-treatment/research-protocol
    December 01, 2019 - Which test (or combination of tests or no test) provides the best guide for whether a patient should … Does the predictive accuracy of either the genetic or phenotypic test or the effectiveness of test-and-treatment … (modifying) predictive test performance, and the effectiveness of test-and-treatment strategies. … for small-study effects. 42 This test is often referred to as a test for publication bias; however, … Genetic test: For the purpose of this review we will adopt the definition of a genetic test proposed

65. PowerPoint Presentation (ppt file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/medical-test-reviews-frameworks.ppt
    June 01, 2012 - regarding the test. … test, a triage test, or an add-on to existing test strategies? … as the old test; plus, the new test has advantages. … The example cases involve a replacement test, an add-on test, and a triage test. … For example, when a new test is as sensitive and as specific as the old test and the new test has advantages

66. PowerPoint Presentation (ppt file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/medical-test-reviews-frameworks.ppt
    June 01, 2012 - regarding the test. … test, a triage test, or an add-on to existing test strategies? … as the old test; plus, the new test has advantages. … The example cases involve a replacement test, an add-on test, and a triage test. … For example, when a new test is as sensitive and as specific as the old test and the new test has advantages

67. Appendix-Table-B-1-Observational-Studies (xls file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/appendix-table-B-1-observational-studies.xlsx
    March 20, 2021 - and no documented previous positive PCR or Ab test. … Participants with negative PCR test but no Ab data were excluded. … Individuals with an antibody test on or after Jan 2020 Individuals with more than one antibody test with … and 1 Ab test during analysis period. … Note: all participants had 2 or more PCR- tests between baseline Ab test and PCR+ test (and most participants

68. PowerPoint Presentation (ppt file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/medical-test-reviews-risk-bias.ppt
    June 01, 2012 - Methods guide for medical test reviews. … Variation in test technology  When the characteristics of a medical test change over time as a result … Sources of systematic bias related to the study’s test protocol include variation in test execution, … of an index test. … the sensitivity and specificity of the test may lead to overoptimistic measures of test performance.

69. PowerPoint Presentation (ppt file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/medical-test-reviews-risk-bias.ppt
    June 01, 2012 - Methods guide for medical test reviews. … Variation in test technology  When the characteristics of a medical test change over time as a result … Sources of systematic bias related to the study’s test protocol include variation in test execution, … of an index test. … the sensitivity and specificity of the test may lead to overoptimistic measures of test performance.

70. Description of a question or questions about a health care test or treatment: o In women with leiomyomas who are candidates for surgery, does the use of adjunctive medical treatment result in better outcomes? (Preoperative adjuvants &… | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/description-of-a-question-or-questions-about-a-health-care-test-or-treatment-o-in-women-with-leiomyomas-who-are-candidates-for-surgery-does-the-use-of-adjunctive-medical-treatment-result-in-better-outcomes-preoperative-adjuv
    November 01, 2017 - Nominated Topics Description of a question or questions about a health care test … SHARE: Description of a question or questions about a health care test … Briefly describe a specific question, or set of related questions, about a health care test … Description of a question or questions about a health care test or treatment: In women with leiomyomas … Internet Citation: Description of a question or questions about a health care test

71. Decision Modeling (ppt file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/medical-test-reviews-decision-modeling.ppt
    June 01, 2012 - Methods guide for medical test reviews. … Define how the test will be used. … Use a framework to identify test consequences and management strategies for each test result. … Second, use a framework to identify test consequences and management strategies for each test result. … Medical test results are indirect.

72. Decision Modeling (ppt file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/medical-test-reviews-decision-modeling.ppt
    June 01, 2012 - Methods guide for medical test reviews. … Define how the test will be used. … Use a framework to identify test consequences and management strategies for each test result. … Second, use a framework to identify test consequences and management strategies for each test result. … Medical test results are indirect.

73. Preoperative-Testing Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/preoperative-testing_executive.pdf
    January 01, 2014 - These tests may be done alone (e.g., only a pregnancy test) or as part of a panel of tests. … the effect of acting on the abnormal test result on perioperative outcomes is unknown … • We do not assesses test results (i.e., abnormal vs. normal) as predictors of outcomes. … test—for example, whether an ECG abnormality is new or not). … Effective strategy to guide pathology test ordering in surgical patients.

74. Genetic Testing for Developmental and Intellectual Disabilities | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/genetic-testing-developmental-disabilities/research-protocol
    December 01, 2019 - A genetic test may reach the market as a commercially distributed test kit approved or cleared by the … test kits include all reagents and instructions needed to complete the test procedure and interpret … Food and Drug Administration; LDT—laboratory-developed test Test Describe the full name of … The Landscape of Genetic Testing for Diagnosing DDs Clinical Condition Test Available Test … If a test has utility, it means that the results of the test can be used to seek effective treatment

75. Imaging Tests to Check for Kidney Stones in the Emergency Department | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/kidney-stone-imaging/consumer
    November 01, 2020 - Overview You have come to the emergency department and the emergency doctor has recommended an imaging test … If the first imaging test is not clear, you may need a second test. … In the past, a CT scan was often used as the first imaging test to check for kidney stones. … If you have an ultrasound first, you may need a second imaging test, which may be a CT scan. … How you feel about possibly needing a second imaging test.

76. PowerPoint Presentation (ppt file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/medical-test-reviews-strength-evidence.ppt
    June 01, 2012 - Methods guide for medical test reviews. … Methods guide for medical test reviews. … Methods guide for medical test reviews. … Methods guide for medical test reviews. … If no test meets these criteria, the interest may be in benefits and harms of adding on a test.

77. PowerPoint Presentation (ppt file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/medical-test-reviews-strength-evidence.ppt
    June 01, 2012 - Methods guide for medical test reviews. … Methods guide for medical test reviews. … Methods guide for medical test reviews. … Methods guide for medical test reviews. … If no test meets these criteria, the interest may be in benefits and harms of adding on a test.

78. Thyroid Tests | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/health-topics/thyroid-tests
    March 10, 2010 - Antithyroid antibody test - measures antibodies (markers in the blood). … One type of nuclear medicine test is the thyroid scan. … Another nuclear test is the radioactive iodine uptake test, or thyroid uptake test.

79. Should subclinical hypothroidism be treated? | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/should-subclinical-hypothroidism-be-treated
    November 01, 2017 - Your Nomination - Please briefly describe in your own words the question about a health care test or … problem have considerable health or financial hardships   There is uncertainty about how well the test … treatment, or intervention works   There is significant potential for side effects/harms using this test … new technology/development   There is new evidence of clinical and/or cost effectiveness for this test … What is the specific purpose of the health care test or treatment you have a question about?

80. Modeling to evaluate benefits and harms of new diagnostic tests compared to established diagnostic tests – uses and limitations (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/benefits-harms-modeling_research.pdf
    November 19, 2009 - High test performance does not guarantee that physicians will act according to test results, that patients … Different Roles A medical test can have different roles in a test-and-treat strategy, depending on … Designing studies to ensure that estimates of test accuracy are transferable. … Subgroup variation in diagnostic test evaluation. … Regression methods for meta-analysis of diagnostic test data.