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301. Prostate-Cancer-Therapies-Update Consumer (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_consumer.pdf
     January 01, 2016 - � PSA blood test: This blood test tells how much PSA (a protein made by the prostate gland) is in … If the test results are not normal, your doctor may recommend more tests, such as a biopsy. … � T1: The cancer is too small to be felt during a digital rectal exam or seen in an imaging test … � T2: The cancer can be felt during a digital rectal exam and may be seen in an imaging test. … During checkups, your doctor may do a digital rectal exam, a PSA blood test, a biopsy, or other tests

302. Disposition of Comments Report for Imaging Tests for the Diagnosis and Staging of Pancreatic Adenocarcinoma (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-pancreas_disposition-comments.pdf
     September 23, 2014 - The report acknowledges that CT is usually the first test. … We did not want to assume that the typical test is also the best test. … the literature to support test strategies. … We note that the accuracy of any given imaging test could not be determined, since studies did not … provide results separately for each screening test.

303. What are the comparative diagnostic accuracy, diagnostic thinking, therapeutic, and patient outcome efficacy of non-invasive tests for the risk stratification of patients with coronary artery disease? | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/what-are-the-comparative-diagnostic-accuracy-diagnostic-thinking-therapeutic-and-patient-outcome-efficacy-of-non-invasive-tests-for-the-risk-stratification-of-patients-with-coronary-artery-disease
     November 01, 2017 - Briefly describe a specific question, or set of related questions, about a health care test or treatment

304. Population: Children < 18 years of age: 1. What are the incidences and prevalences of non-inflammatory pain syndromes (e.g., benign hypermobility syndrome, patellofemoral stress syndrome, fibromyalgia, and growing pain) in children and… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/population-children-18-years-of-age-1-what-are-the-incidences-and-prevalences-of-non-inflammatory-pain-syndromes-eg-benign-hypermobility-syndrome-patellofemoral-stress-syndrome-fibromyalgia-and-growing-pain-in-children-and-a
     November 01, 2017 - Briefly describe a specific question, or set of related questions, about a health care test … patterns escalate the economic and social burden of medical care through their high rate of false positive test

305. Topic 0613 Tympanostomy Tubes NSD FINAL (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0765-150129.pdf
     November 03, 2014 - Questions from Nominator: Key Question #3: What is the comparative effectiveness of obtaining a hearing test … years, being considered for tympanostomy tubes Intervention(s): Hearing testing Comparator(s): No test … Should clinicians obtain a hearing test prior to inserting tympanostomy tubes? 3.

306. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0012_03-21-2008.pdf
     January 01, 2008 - What is the yield of screening with a TSH test? … Since the prevalence of high and low TSH test Subclinical Hypothyroidism Nomination Summary Document

307. Renal-Function Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/renal-function_research-protocol.pdf
     June 13, 2013 - This may lead to misclassification and reduce the utility of the diagnostic test. … Publication bias will be examined by using Begg’s test and Egger’s test, including evaluation of the … Methods Guide for Medical Test Reviews. Rockville, MD. 2010. … Operating characteristics of a rank correlation test for publication bias. … kidney-disease-test-protocol.2 kidney-disease-test-protocol.3 kidney-disease-test-protocol.4 kidney-disease-test-protocol

308. Towards a Framework for Communicating Confidence in Methodological Recommendations for Systematic Reviews and Meta-Analyses (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methodological-recommendations-framework-communications_research.pdf
     September 01, 2013 - The original paper emphasized that this test was valid in the equal effect setting. … Chapter 8: meta-analysis of test performance when there is a "gold standard". … Comprehensive Overview of Methods and Reporting of Meta-Analyses of Test Accuracy. … Arcsine test for publication bias in meta- analyses with binary outcomes. … Diagnostic test accuracy working group: Handbook for diagnostic test accuracy reviews. 2011; http:

309. C-Diff-Infections-Surveillance-140925 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/c-diff-infections-surveillance-140925.pdf
     January 01, 2014 - to have used clinical stool specimen, compared at least two diagnostic tests, and used a reference test … Rapid and sensitive loop-mediated isothermal amplification test for Clostridium difficile detection … challenges cytotoxin B cell test and culture as gold standard. … test used. … difficile, the illumigene C. difficile test and the Xpert C.

310. Disposition of Comments for CER 158 Diagnosis of Gout (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/gout-diagnosis-disposition-160727.pdf
     February 24, 2016 - Regarding the circularity of KQ1b, the test whose accuracy was of primary interest (or at least how … the accuracy of the test was affected by number and identity of affected joints) was synovial fluid … Even if these test well so far I am concerned. … The population of interest is those to whom the diagnostic test would be applied to - this includes … This obviously influences the reported sensitivity of the test.

311. Health Screening | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/health-screening
     April 07, 2025 - After a screening test, ask when you will get the results and whom to talk to about them.

312. Effective Health Care (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0334_08-04-2010.pdf
     January 01, 2010 - lead to improvements in health outcomes compared to a no-testing strategy, and in whether the genetic test … comparison of testing strategies, there exist several treatment options that may be selected based on the test

313. An analytical framework for quantifying components of variability in prescriber decisions (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/instrumental-variable-methods_research.pdf
     April 01, 2010 - These tests assume that one has available a valid IV and the test then attempts to determine whether … F(1,63051)=12.30 P-val=0.0005 Anderson-Rubin Wald test Chi-sq(1)=12.30 P-val=0.0005 … (Cragg-Donald Wald F statistic): 1.5e+04 Stock-Yogo weak ID test critical values: 10% … F(1,63045)=19.74 P-val=0.0000 Anderson-Rubin Wald test Chi-sq(1)=19.74 P-val=0.0000 … (Cragg-Donald Wald F statistic): 1.5e+04 Stock-Yogo weak ID test critical values: 10%

314. Disposition of Comments Report for Core Needle and Open Surgical Biopsy for Diagnosis of Breast Lesions: An Update to the 2009 Report (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_disposition-comments.pdf
     September 10, 2014 - Why did this report shift to analysis of comparative test performance? … We believe that the evidence on each test of interest is of moderate strength. … We have provided additional information on the definition of all diagnostic test result categories. … Results Page 43: Wait time for test results. … The Authors mention a study that used "a microwave processor to reduce wait times for test results

315. Genetic Testing for Developmental Disabilities, Intellectual Disability, and Autism Spectrum Disorder | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/genetic-testing-developmental-disabilities/technical-brief
     December 01, 2019 - We also identified one test cleared by the U.S. Food and Drug Administration.

316. S89 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/s89.pdf
     October 01, 2007 - In the current study of MCV, we specified an alpha of 0.05 for a 1-sided test. … †One-sided test; when relative risk �1, the log likelihood ratio was set to 0. … †One-sided test; when relative risk �1, the log likelihood ratio was set to 0. … A maximized sequential probability ratio test for vaccine and drug safety surveillance. … A maximized sequential probability ratio test for drug and vaccine adverse event surveillance.

317. Evidence Report on the (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
     May 24, 2010 - for toxins if the first step test is positive. … Physicians may not always be sufficiently educated as to which diagnostic test is best to use and how … best to resolve a suspected false negative result (e.g., evidence suggests retesting with the same test … • Outcomes for each question: Diagnostic Test Outcomes 1. Sensitivity 2. Specificity 3. … • Timing: Diagnostic testing: time to test http://www.effectivehealthcare.ahrq.gov/�

318. Benefits and Harms of Routine Preoperative Testing: Comparative Effectiveness | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/preoperative-testing/research
     December 01, 2019 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

319. Gout Executive-2016 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/gout_executive-2016.pdf
     January 01, 2016 - However, if no such studies could be identified for a diagnostic test of interest, studies were also … Patient-level factors that influence test behavior have also been understudied. … Assessing risk of bias as a domain of quality in medical test studies. … In: Methods Guide for Medical Test Reviews. AHRQ Publication No. 12-EHC017. … Methods Guide for Medical Test Reviews. AHRQ Publication No. 12-EHC017.

320. Disposition of Comments for Use of Natriuretic Peptide Measurement in the Management of Heart Failure (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_disposition-comments.pdf
     November 20, 2013 - General In point of fact, this document may wish to make the comment that like no other diagnostic test … Simply adding another test because it has excellent rule out diagnostic accuracy does not make sense … But is ruling out the purpose the test is used for? … What will happen to test positive patients and test negative patients? … The length of follow up was unrestricted – there was not limit on how long after the index test the