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101. comparison of tight management vs less control among pts with type 2 dm who are hospitalized with blood glucose related illnesses | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/comparison-of-tight-management-vs-less-control-among-pts-with-type-2-dm-who-are-hospitalized-with-blood-glucose-related-illnesses
     November 01, 2017 - Your Nomination - Please briefly describe in your own words the question about a health care test or … problem have considerable health or financial hardships   There is uncertainty about how well the test … new technology/development   There is new evidence of clinical and/or cost effectiveness for this test … What is the specific purpose of the health care test or treatment you have a question about? … risk assessment for a disease   Risks or harms that can come from a disease identification tool or test

102. Cervical Cancer Screening | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/cervical-cancer-screening
     There are two types of tests: the Pap test and the HPV test. … With the Pap test, the lab checks the sample for cancer cells or abnormal cells that could become cancer … With the HPV test, the lab checks for HPV infection.

103. Comparative Effectiveness of Fecal DNA Testing in Screening for Colorectal Cancer in Average Risk Adults. (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/colorectal-cancer-screening_disposition-comments.pdf
     February 01, 2012 - In both cases the test performed poorly. … This test, ColoSure®, was developed and is provided by LabCorp as a laboratory developed test and is … as a fecal immunochemical test. … This test, ColoSure®, was developed and is provided by LabCorp as a laboratory developed test and is … All clinical validity (clinical test performance) is based on the analytic validity of the test.

104. Prostate Cancer Screening | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/prostate-cancer-screening
     There is no standard screening test for prostate cancer . … One test is the digital rectal exam (DRE). … Another test is the prostate-specific antigen (PSA) blood test.

105. Biomarkers for Assessing and Managing Iron Deficiency Anemia in Late-Stage Chronic Kidney Disease | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/chronic-kidney-disease-anemia-2011/research
     December 01, 2019 - The remaining 12 studies investigated the test performance of newer or classical markers of iron status … There is also a low level of evidence that sTfR has a similar test performance compared with classical … iron treatment, but the strength of evidence was insufficient to come to a conclusion regarding the test … For Key Question 4 (factors affecting the test performance and clinical utility of newer markers), we … Furthermore, we can conclude that there is insufficient evidence to determine the test performance of

106. Antinuclear Antibody, Rheumatoid Factor, and Cyclic-Citrullinated Peptide Tests for Evaluating Musculoskeletal Complaints in Children | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/musculoskeletal-complaints-tests-children/research
     December 01, 2019 - To explore differences in test performance for accuracy modifiers including age, sex, race or ethnicity … To evaluate the impact of test results on clinical decisionmaking and clinically important outcomes such … The 12 case-control studies that examined other test-disease combinations did not specifically address … The strength of evidence is insufficient to determine the test performance of ANA or CCP to diagnose … No studies examined clinically important outcomes such as the impact of the test results on referrals

107. Routine Preoperative Testing: Comparative Effectiveness Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/preoperative-testing/research-protocol
     December 01, 2019 - Aberrant test results may lead to cascade testing (either appropriate if the test result signals a real … To systematically review test performance would require a broader review of each test--beyond routine … We will not assesses test results (i.e., abnormal vs. normal test results) as predictors of outcomes. … To include any preoperative test evaluated by an eligible study. … Effective strategy to guide pathology test ordering in surgical patients.

108. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/musculoskeletal-complaints-tests-children_research-protocol.pdf
     September 29, 2010 - The rheumatoid factor (RF) test is the most commonly used serological test to determine the presence … A CCP test may also be ordered as a follow-up to a negative RF test when clinical signs, such as symmetrical … The ANA test is the primary screening test for SLE: an abnormal FANA titre with a homogeneous or speckled … represents a perfect test; an area of 0.5 represents a worthless test. … The strength of evidence for primary (diagnostic test performance) and secondary (test referrals, additional

109. Diagnosis and Treatment of Clinical Alzheimer's-type Dementia (CATD) (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/catd-protocol-draft_0.pdf
     November 02, 2018 - Cognitive Tests to be Assessed for Diagnostic Accuracy Cognitive Test Categories Cognitive Test Names … Memory) Verbal memory Varies by test Confrontation naming (e.g., BNT) Language Varies by test … = Continuous Performance Test, CVLT = California Verbal Learning Test, DKEFS = Delis-Kaplan Executive … Information extracted only from diagnostic studies will include diagnostic test, reference test, and … thresholds, reference test thresholds, and measures of test performance are comparable.

110. Diagnosis and Treatment of Clinical Alzheimer's-type Dementia (CATD) | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/alzheimers-type-dementia/protocol
     August 01, 2020 - Cognitive Tests to be Assessed for Diagnostic Accuracy Cognitive Test Categories Cognitive Test Names … memory Varies by test Confrontation naming (e.g., BNT) Language Varies by test Verbal fluency-letter … Alzheimer's Disease, COWAT = Controlled Oral Word Association Test, CPT = Continuous Performance Test … Information extracted only from diagnostic studies will include diagnostic test, reference test, and … thresholds, reference test thresholds, and measures of test performance are comparable.

111. A1C | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/health-topics/a1c
     X Y Z Health Topics A1C Description A1C is a blood test … This test is different from the blood sugar checks that people with diabetes do every day. … Your A1C test result is given in percentages. … Type 2 diabetes is above 6.5 percent If you have diabetes, you should have the A1C test at least twice

112. 13-MDM347013 30..38 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/outcomes-testing-evaluation_research.pdf
     January 01, 2009 - If so, they should be incorporated into test evaluation. … test results are all connected and can lead to changes in patients’ behavior. … symptoms or enable them to revise future life plans in light of their test results. … and followup, which may affect the net benefit of the test on health outcomes. … are clear for those who test positive and the downsides of treatment are known for those who test negative

113. 13-MDM347013 30..38 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/whitepaper4-bossuyt02262010-2.pdf
     January 01, 2009 - If so, they should be incorporated into test evaluation. … test results are all connected and can lead to changes in patients’ behavior. … symptoms or enable them to revise future life plans in light of their test results. … and followup, which may affect the net benefit of the test on health outcomes. … are clear for those who test positive and the downsides of treatment are known for those who test negative

114. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
     November 22, 2011 - Which test (or combination of tests or no test) provides the best guide for whether a patient should … (modifying) predictive test performance, and the effectiveness of test-and-treatment strategies. … for small-study effects. 42 This test is often referred to as a test for publication bias; however … Genetic test: For the purpose of this review we will adopt the definition of a genetic test proposed … Phenotypic test: A phenotypic test is a means of evaluating the physiological characteristics of a

115. Musculoskeletal-Complaints-Tests-Children Surveillance (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/musculoskeletal-complaints-tests-children_surveillance.pdf
     January 08, 2013 - reported Sn of 100% for ANA test. … ) examined the prevalence of a positive IgM-RF test for pSLE. … patients who had an RF test and were seen at a children’s hospital. … ) examined the prevalence of a positive IgM-RF test for pSLE. … patients who had an RF test and were seen at a children’s hospital.

116. Improving Access to and Usability of Systematic Review Data for Health Systems Guidelines Development | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/systematic-review-data/methods-report
     March 01, 2020 - presentations of systematic review data in formats that would address the identified needs, and (3) to test … To develop and test alternative formats for dissemination, we assessed stakeholder needs through qualitative … the literature search to several existing software tools in order to select two tools for the pilot test … data may require the granularity of MAGICapp or the freedom of Tableau and (2) the need for EPCs to test … government data rights, we recommend a follow-on pilot be conducted to allow systematic review teams to test

117. preoperative-testing-protocol-130514 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/preoperative-testing_research-protocol.pdf
     May 14, 2013 - • Aberrant test results may lead to cascade testing (either appropriate if the test result signals … To systematically review test performance would require a broader review of each test—beyond routine … We will not assess test results (i.e., abnormal vs. normal test results) as predictors of outcomes. … To  include  any   preoperative  test  evaluated  by  an  eligible  study.   … Effective strategy to guide pathology test ordering in surgical patients.

118. Thrombosis plays a a key role in the pathophysiology of myocardial infarction-a leading cause of morbidity and mortality. There have been a number of devices proposed for mechanical thrombectomy in patients with in the setting of acute… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/thrombosis-plays-a-a-key-role-in-the-pathophysiology-of-myocardial-infarction-a-leading-cause-of-morbidity-and-mortality-there-have-been-a-number-of-devices-proposed-for-mechanical-thrombectomy-in-patients-with-in-the-settin
     November 01, 2017 - Your Nomination - Please briefly describe in your own words the question about a health care test or … problem have considerable health or financial hardships   There is uncertainty about how well the test … new technology/development   There is new evidence of clinical and/or cost effectiveness for this test … What is the specific purpose of the health care test or treatment you have a question about? … risk assessment for a disease   Risks or harms that can come from a disease identification tool or test

119. Noninvasive Testing for Coronary Artery Disease | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/coronary-artery-disease-testing/research-protocol
     December 01, 2019 - The first step is assessing pre-test likelihood that the patient has CAD. … for test-positive people. … for evaluation using a noninvasive test other than resting ECG Table 1 . … Methods Guide for Medical Test Reviews. AHRQ Publication No. 12-EC017. … positive and are treated with those who test negative and are not treated.

120. Imaging Tests for the Staging of Colorectal Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/colorectal-cancer-staging/research-protocol
     December 01, 2020 - Test performance . … Studies must compare the test or test combination being evaluated to a reference standard (see below) … Studies must directly compare the test or test combination to another test or test combination of interest … Studies must directly compare the test or test combination to another test or test combination of interest … Test Criteria Type of test .