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  1. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1306.pdf
    June 01, 2013 - In the absence of randomized controlled trials or long-term outcomes data, some experts were uncertain … Long-term PN can lead to serious side effects such as liver damage, the risk of which increases the … If teduglutide proves to be generally tolerable in patients with SBS over the long term, reductions … In the absence of results from randomized or long-term trials, some experts are unsure about the true … Long- term outcomes of an endoscopic myotomy for achalasia: the POEM procedure.
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_executive.pdf
    August 01, 2012 - exaggerated treatment effects.9 Future Research More longitudinal research is needed on the long-term … Short- and long-term evaluations of the effectiveness of FGAs and SGAs with patient subpopulations, … Only two studies with long-term followup were identified; hence, evidence on these important AEs is … Long- term longitudinal studies of at least 2-year duration are needed to detect important differences … Finally, data on long-term safety are lacking and urgently needed. 14 References 1.
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/vaccine-safety_research-protocol.pdf
    September 18, 2012 - vaccines included in the 2011 immunization schedule recommended for U.S. adults18* are safe in the short term … (within 30–42 days following immunization) or long term (>42 days after immunization)? … immunization schedules recommended for U.S. children and adolescents in 201119* are safe in the short term … (within 30–42 days following immunization) or long term (>42 days after immunization)? … The following structure was used in the IOM keyword search strategy: “vaccine term” AND “health term
  4. Obesity (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - Most experts also thought that this intervention could help many patients achieve short-term weight … Experts cited the cost, need for daily injections, and unknown long-term safety profile as potential … weight loss, but they would prefer to see longer-term data to analyze how well patients maintained … safety data with new drug applications and commit to long-term postmarket studies.43-46 Until mid- … Studies better defining the potential long-term risks (breast cancer and cardiovascular risks) need
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/data-repository-reviews_white-paper.pdf
    September 01, 2012 - implementation of data curation and quality assurance procedures, as well as the day-to-day and long-term … successful resolution of these issues requires careful deliberation and will be critical to the long- term … determined that, primarily, the key to realizing the above enumerated principles and ensuring the long-term … effective quality control processes is crucial to inspire user trust and will encourage SRDR’s long-term … AHRQ has invested in the development of the SRDR for the past 2 years; however, its long- term funding
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-deprescribing.pdf
    February 01, 2024 - the care continuum, including outpatient clinics, emergency departments, acute care hospitals, long-term … improve patient safety across the healthcare system—from hospitals to primary care practices, long-term … III report on this topic Published in 2018 or earlier Setting Inpatient, outpatient, and long-term … patient education Primary care, outpatient clinics, urgent care, acute care hospitals, long- term … Outpatient clinics, acute care hospitals, long-term care, community pharmacies Age ≥65 years
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/living-systematic-reviews-full-text-articles-white-paper.pdf
    January 01, 2024 - medications, and nonpharmacological interventions, are associated with limited efficacy in the long term … Long- term effectiveness and safety of Nabiximols (tetrahydrocannabinol/cannabidiol oromucosal spray … Long- term effectiveness and safety of medical cannabis administered through the metered- dose Syqe … Long- term effectiveness and safety of medical cannabis administered through the metered- dose Syqe … Long- term effectiveness and safety of nabiximols (tetrahydrocannabinol/cannabidiol oromucosal spray
  8. effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-are-the-best-options-for-fertility-treatment-in-terms-of-safety-and-effectiveness
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth_research.pdf
    January 01, 2020 - The top-tier methodologic improvements focused on improving the capture of short- and long-term birth … Develop registries that capture both short-term and long-term outcomes. … Develop registries that capture both long-term and short-term outcomes 15. … Develop registries that capture both short-term and long-term outcomes. … Develop registries that capture both long term and short term outcomes. 15.
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-surveillance_research-protocol.pdf
    May 19, 2011 - However, both surgical and radiation treatments result in significant short- and long-term adverse … Decisionmaking tools and aids Question 4 What are the comparative short- and long-term outcomes … surveillance‖ and other observational strategies Immediate treatments KQ4 KQ4 Short- and long-term
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-seniors-death_research.pdf
    August 01, 2007 - Objective: To assess the short-term mortality in a population-based cohort of all British Columbia seniors … We sought to assess the short-term mortality in a population-based cohort of all British Columbia seniors … Evaluating short-term drug effects in claims databases using physician-specific prescribing preferences … A naturalistic, long-term, retrospective, comparative study. … Simultaneous assessment of short-term gastrointestinal benefits and cardiovascular risks of selective
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-nitrous-oxide_research-protocol.pdf
    August 24, 2011 - ‖ The term ―pain relief‖ was replaced with ―pain management‖, as the term ―relief‖ may imply total … Long-term maternal, child, and occupational health outcomes. … Long-term outcomes will include associated birth outcomes. … The term ―pain relief‖ was replaced with ―pain management‖, as the term ―relief‖ may imply total dissipation … Outcomes related to birth will be classified as long-term, and include the primary outcomes as well
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_research-protocol.pdf
    June 11, 2014 - hemorrhage-postpartum-protocol-140611 Evidence-based Practice Center Systematic Review Protocol Project Title: Management of Postpartum Hemorrhage I. Background and Objectives for the Systematic Rev…
  14. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/11_peptic_ulcer_potential_high_impact_2012-12-111.pdf
    January 01, 2012 - In the absence of randomized controlled trials or long-term trials, some experts were uncertain of … Long- term outcomes of an endoscopic myotomy for achalasia: the POEM procedure. … term=PO EM+and+achalasia&Search=Search. 38. … term=POEM+and+achalasia&Search=Search http://www.clinicaltrials.gov/ct2/results? … What are the long-term outcomes for children with SBS? [internet].
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
    January 01, 2017 - The evidence is less applicable to long-term outcomes, such as function, long-term quality of life, … (6 to 12 weeks) than longer term (1 to 2 years). … The evidence is not applicable to long-term followup (greater than 2 years). … Long- term harms are not assessable in short-term studies, and relying on observational evidence has … • Additional well-designed long-term studies are needed.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccines-safety-protocol-130325.pdf
    September 18, 2012 - vaccines included in the 2011 immunization schedule recommended for U.S. adults18* are safe in the short term … (within 30–42 days following immunization) or long term (>42 days after immunization)? … immunization schedules recommended for U.S. children and adolescents in 201119* are safe in the short term … (within 30–42 days following immunization) or long term (>42 days after immunization)? … The following structure was used in the IOM keyword search strategy: “vaccine term” AND “health term
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-emergency_research-protocol.pdf
    July 18, 2011 - Side effects The second objective of this CER is to assess important immediate and longer term side … Prevention of Recurrence Some patients with status migrainosus suffer a short-term recurrence that … ED for acute migraine. 19 However, they are infrequently used and have important short- and long-term … The followup period for longer term outcome studies. … Question 3 What are the associated short-term adverse effects of these parenteral pharmacological
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_research-protocol.pdf
    December 09, 2009 - Not only are short-term mortality rates high, but a large proportion of those patients who survive never … 1-year postfracture.8 Up to 25 percent of hip fractures occur in continuing care facilities (long-term … The term “comparative” has been removed from the intervention and the statement “or other interventions … The term short and long have been replaced with acute and chronic, respectively. c. KQ2: i. … to participate in rehabilitation, the quality of sleep in hospital, and length of stay and/or long-term
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0651-131114.pdf
    June 20, 2013 - Comparator(s): All other treatment options Outcome(s): Increases in short- and long-term benefits in … elimination of low back pain, improvements in functioning and quality of life; decreases in short- and long-term
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-update_executive.pdf
    August 01, 2014 - 3 KQ 1c: What are the longer term effects (>6 months) on core symptoms (e.g., social communication … KQ 4: What is the evidence that effects measured at the end of the treatment phase predict long-term … Further, the long-term impact of these early skill improvements is not yet clear, and many studies did … Most studies reported short-term gains in either parent- rated social skills or directly tested emotion … Treatment Effects That Predict Long- Term Outcomes Few studies assess end-of-treatment effects that

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