-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/insomnia_clinician.pdf
August 01, 2017 - Drug Administration (FDA) has
approved several prescription drugs for insomnia, typically
for short-term … Effectiveness was demonstrated across modes
of delivery and was sustained in the long term (at least … sleep outcomes, primarily in older patients (low to
moderate SOE).
�� Evidence regarding the long-term … Pharmacological Therapy: Adverse Effects (See Table 3)
�� Evidence regarding the long-term (more than … Evidence regarding their longer-term
efficacy and safety is limited or lacking.
�� Outcome reporting
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effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-37-opiod-use-adults-comments.pdf
November 03, 2020 - Indeed in some studies of long term opioid
use, overdose deaths seem to diminish with age. … Methods Please clarify that you are considering long term
opioid therapy as an outcome. … However, we have added a statement about
intermediate-term work that should be
conducted: Intermediate-term … Long-term opioid; should not
be categorized as a negative outcome in itself. … indicator of greater need for long-term use to
manage chronic pain.”
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_disposition-comments.pdf
November 27, 2012 - The term "IRLS responders" is used
frequently but I am not sure what you mean by this term. … Peer Reviewer
#1
Results Pg 18 and pg 53: Short-term Harms. … and long-term harms. … On the
contrary, refs 41-53 all provide long-term data. … We defined short term studies a priori and continue to
believe that adequately assessing the long-term
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_executive.pdf
February 01, 2012 - of treating many of the pediatric diseases
with HSCT has resulted in an increased number of
long-term … As improvements in survival have
been achieved, there is greater concern about long-
term effects and … comparative effectiveness of
HSCT and conventional chemotherapy regarding overall
survival, long-term … Practitioner review: long-term consequences
of childhood cancer. … Long-term cause-
specific mortality among survivors of childhood cancer.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-outcomes_research-protocol.pdf
March 03, 2014 - such a
balance is crucial in serious mental illness (SMI), where adequate treatment requires long-term … , and either major depression with psychotic features or treatment-resistant depression, is
a long-term … What are the expected short-term developments in this field that may address
these uncertainties or … What are potential long-term (10-year) developments in this field?
III. Methods
1. … (≤ 6 months), intermediate term, and long term (≥12 months) § TBD
Setting § Inpatient or outpatient
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/omega-3-maternity_executive.pdf
October 01, 2016 - infant n-3 FA
supplementation did not alter growth
patterns (attainment of height or weight)
of full-term … Key Question 3: Maternal or childhood adverse events:
– What are the short and long-term risks related … or preterm human infants at or after birth
– What are the short and long-term risks associated
with … Pooling studies that assessed supplementation of healthy
term infants with formula containing any n- … No significant
effects of supplementations were seen on cognitive
development among term infants.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
June 01, 2011 - This review summarizes the evidence on the
comparative long-term benefits and harms of ACEIs,
ARBs, and … ACEIs and ARBs appear to have similar long-term effects on
ARB); blood pressure among individuals with … Relatively few studies assessed
Moderate (ACEI these outcomes over the long term.
vs. … Given the
importance of these issues, it is notable how few large,
long-term, head-to-head studies have … )
• Long-term comparisons of direct renin inhibitors
with ACEIs and ARBs.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0404_01-14-2011.pdf
January 01, 2011 - What are the long-term (> 90-day) mortality, morbidity, and functional outcomes
associated with various … for guiding the diagnosis and management of PAH as well as for use in evaluating
short- and long-term … for PAH over
the past 3 decades; however, there continues to be a lack of data supporting the long-term
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0024_06-09-2008.pdf
January 01, 2008 - Nominator 2 (anonymous) is interested in
the long-term effects of treating older patients with antipsychotics … It will be important that the review from the EHC Program focus on key long-term, real life … effectiveness
trials and comparative harms rather than short-term efficacy trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-evidence-summary-2022-update_0.pdf
January 01, 2022 - In
patients with chronic (mainly neuropathic) pain with short-term treatment (4 weeks to
<6 months) … Key Question 1: Benefits of cannabinoids for chronic pain compared with placebo in the
short term (4 … improvements in pain with some cannabis products, but the impact on
moderate or long-term outcomes … Evidence is too limited to
compare effects on serious and long-term harms, even indirectly. … Only short-term evidence is available for cannabis-related interventions containing
THC and/or CBD to
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-treatment_clinician.pdf
November 01, 2016 - Conclusions
Several interventions for low back pain are associated with
small-to-moderate, primarily short-term … moderate SOE).
�» Note: No evidence supporting the effectiveness
and safety of opioids in the long term … SRs + to ++ (pain)
+ (function)
��� to
���
Physical therapy Pain, function (short-
and long-term … SR ++ ���
Function 1 SR + ���
Another NSAID Pain 6 RCTs ↔ ���
Opioids—tramadol Placebo Pain (short-term … ) 1 SR + 2 additional RCTs ++
���
Function (short-term) +
Opioids—other§ Placebo Pain, function
(
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioid-chronic-pain-surveillance-report-2.pdf
April 01, 2022 - placebo, short-term pain
Opioids associated with small
improvement in short-term pain
• SOE: High … placebo, short-term
function
Opioids associated with small
improvement in short-term
function
• … followup (1 to <6 months), intermediate-term followup
(6 to <12 months), and long-term followup (≥12 … followup (1 to <6 months), intermediate-term followup (6 to
<12 months), and long-term followup (≥12 … followup (1 to <6 months), intermediate-term followup (6 to
<12 months), and long-term followup (≥12
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
September 01, 2012 - of all perinatal morbidity
and mortality and are the leading cause
of infant mortality and long-term … • Longer term outcomes (e.g., neurodevelopmental
delay and future reproductive outcomes)?
KQ2. … • Longer term outcomes?
KQ3. … Long-term effects have not
been well studied. … Across indications, data are
sparse to evaluate influence on near-term and long-term
maternal and infant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_disposition-comments.pdf
March 05, 2015 - term=uspstf+vitamin+E+2014
http://www.ncbi.nlm.nih.gov/pubmed? … The term “sexual interest” has been replaced by
“sexual desire”. … Progestogen is an all-
inclusive term which includes synthetic progestins (e.g. … When discussing trials
such as the WHI, you may use the term “progestin.” … The term ‘general medicine’ is not entirely clear to
me.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-gain-prevention_disposition-comments.pdf
March 25, 2013 - The question “What is the effectiveness of weight loss
interventions for long-term weight stability? … Relationship of a large weight loss to long-term weight change
among young and middle-aged US women. … For example, almost explicitly, a
perfectly or nearly perfectly performed, unbiased, long-
term RCT … , sufficiently powered
RCT of long-term weight gain with little cross-over,
noncompliance, or loss … long-term observational studies)
actually provide “high” rather than "moderate”
evidence?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/infertility_research-protocol.pdf
October 12, 2015 - time frames, trade-offs between short-term success and long-term
2! … Short-term
!! … Long-term
!! … Short- or long-term health outcomes
•! Timing :
o! Short term:
!! … Long-term:
10!
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_disposition-comments.pdf
June 12, 2013 - Reviewer 9
(Peer)
ES On page 42 [ES 2] line 41 the term long-term survival is used to should
be defined … In reviewing the sentence in question, we concluded that
using the term “long-term” immediately before … We defined the term “BT” as brachytherapy in the
sentence on line 33, ES-3. … We removed the term “radical” and simply refer
to radiotherapy (RT). … This was revised by removing the term “continuous” to
reflect this comment.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
March 01, 2011 - decreased insulin
secretion by pancreatic beta cells, leading
to chronic hyperglycemia and associated
long-term … Long-term complications of diabetes
include microvascular disease, such as
retinopathy and blindness, … These mixed
results suggest the need for further research, including
investigation of the long-term safety … benefits, if any, of the addition of insulin to
oral agents, and the long-term effects on mortality … to engage in longer term studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_executive.pdf
September 01, 2009 - For patients who require intensive
lipid-modifying therapy, what are the comparative
long-term benefits … Do these regimens differ in reaching
LDL targets (or other surrogate markers), short-
term side effects … considered
short term. … regarding long-term clinical outcomes. … LDL-c Targets, Short-Term Side
Effects, Tolerability, and Adherence
Surrogate markers are biological
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-treatment-adherence_disposition-comments.pdf
December 20, 2012 - We changed the term to extended
rapid viral response. … To make
the term consistent within our report,
we opted to use the term treatment
duration. … The term “adherence” here is not precise
enough. … We have
revised our recommendations
regarding long-term outcomes. … ” rather than the generic term of
“counseling” methods.