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Showing results for "target".

21. Technical Brief No. 35, Characteristics of Existing Asthma Self-Management Education Packages - Summary (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/asthma-self-mgmt-summary.pdf
    April 01, 2020 - it challenging to identify best practices because of differences in format, delivery mechanisms, target … steps needed to implement AS-ME include identifying the asthma population, delivery setting, and target

22. Arthritis and Nontraumatic Joint Disease (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - potential diffusion (e.g., in phase III trials or for which some preliminary efficacy data in the target … About 47% of patients with gout do not achieve target goals for sUA levels (<6 mg/dL) with the standard … contraindication to a xanthine oxidase inhibitors who were given lesinurad as monotherapy achieved target … trial, patients given lesinurad 200 mg or 400 mg, and 54% and 59%, respectively, achieved the sUA target … by the manufacturer showed that more patients treated with lesinurad and febuxostat achieved the target

23. Asthma-Immunotherapy-2011 Research (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2011_research.pdf
    January 01, 2011 - defined external validity as the extent to which the results of a study can be generalized to the target … population.5 Applicability may differ from external validity by the definition of the target population … F Included association with risk factors without clear definition of the target population Minor … population Minor flaw Included Incidence estimation without clear target population Minor … population) Not reported Poor reporting Level C <40 (or less than cut off specific for the target

24. Disposition of Comments Report for Antinuclear Antibody, Rheumatoid Factor, and Cyclic-Citrullinated Peptide Tests for Evaluating Musculoskeletal Complaints in Children (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/musculoskeletal-complaints-tests-children_disposition-comments.pdf
    March 07, 2012 - The target audience is implied but not formally stated. … Perhaps this is known to all rheumatologists; however, this is not the target audience. … The major finding is clear for the target population (children with MSK pain) that the use of these … The registries do not include children with MSK pain, which was our target audience. … A single table would also suffice if headings are added for target condition and index test.

25. Primary Hypofractionated Radiation Therapy for Localized Prostate Cancer: Research Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-protocol.pdf
    April 17, 2024 - Key Question 4 was revised to cover a broader range of target volumes and included the investigation … In KQ4, the comparison involves different target volumes—such as the prostate alone, prostate with seminal … Target volumes compared to each other [all grouped by type of hypofractionation (MHF and UHF) KQ 5. … Fiducial markers: Small markers placed in or near the tumor to help guide and precisely target radiation … Organs at risk (OARs): Critical normal tissues near the target area of radiation that must be protected

26. Executive Summary_Comparative Effectiveness Review No. 259: Partial Breast Irradiation for Breast Cancer (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-259-partial-breast-irradiation-executive-summary.pdf
    January 01, 2023 - as a component of breast conserving therapy has traditionally included the whole breast volume as a target … effectiveness and harms are influenced by patient, tumor, and treatment factors, including treatment modality, target … Although the volume of the treatment target relative to the breast, dose/fractionation schedule, and … Defining an optimal radiation dose, fractionation, and target size using contemporary techniques for

27. Communication and Dissemination Strategies To Facilitate the Use of Health-Related Evidence (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-evidence-communication_executive.pdf
    November 01, 2013 - Evidence reports typically target scientifc researchers in related felds, rather than the patients … of various ways of communicating uncertainty associated with health-related evidence to different target … They use various strategies to communicate evidence so that target audiences can better understand it … Possible moderators of interest for all KQs included risk of bias, study size, and target audience. … we were asked to examine various strategies for communicating and disseminating evidence to these target

28. rheumatoid-arthritis-medicine-update-protocol-170515 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-update_research-protocol.pdf
    May 15, 2017 - Based on these findings, drug therapy may need to change at regular intervals until the treatment target … approach, for symptomatic early RA, based on a low level of evidence.13 Treating to target includes … They also recommend a treat-to-target approach to remission or low disease activity. … If the treatment target is not achieved with the first DMARD, such as MTX, a different csDMARD (e.g. … Unlike step up or step down therapy, clinical studies using treat to target strategies use stringent

29. Interventions Targeting Sensory Challenges in Children With Autism Spectrum Disorders - An Update (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-interventions-disposition.pdf
    May 26, 2017 - Target population is well described and defined, but it would be helpful to the reader if the authors … Intervention consists of active, individually-tailored, sensory motor activities that target these underlying … Auditory interventions are very specific interventions that target only one sensory system and are not … TEP Reviewer #4 Discussion/Con clusion The review of sensory therapies is also concise and on target

30. Microsoft Word - 3-DKE274__ACEI-ARB-DRI__Comments_Disposition_Table-21_Jan_2011 cyk _2_.docx (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_disposition-comments.pdf
    October 07, 2011 - The target dose is 32 mg once daily, which is achieved by doubling the dose at approximately 2-week … We have commented in the future research section that combining studies across target conditions may … Most reviews focus on the target condition for inclusion (i.e. … ARBs have limited inclusion of studies to those conducted in patients with the target condition at … It is likely that combining studies reporting identical outcomes, but in different target populations

31. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
    June 01, 2011 - throughout the world, hypertension results in substantial morbidity because of its impact on numerous target … Although ACEIs and ARBs both target the renin system and are treated by clinicians as being equivalent … Trials comparing ACEIs, ARBs, and direct renin inhibitors in these target conditions often report the … For evaluation of rarer events (e.g., mortality or angioedema) it may be worth combining data across target … Future research should consider this strategy and evaluate the extent to which results differ across target

32. Future Research Needs for Childhood Obesity Prevention Programs (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/child-obesity-future_research.pdf
    March 31, 2010 - Our stakeholders greatly favored studying interventions that target caloric restriction over other targeted … Options for Delphi Round 2 Age Race/Ethnicity Socioeconomic Status Setting Target Young Black Low … they had to select one from each category (age, race/ethnicity, socioeconomic status, setting, and target … When the stakeholders were asked to specify the target of intervention during round 2, they favored … Our stakeholders greatly favored studying interventions that target caloric restriction over other targeted

33. Lumbar-Fusion-Draft-Report-Appendix-D (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/lumbar-fusion-draft-report-appendix-d.xlsx
    January 01, 2019 - 66 A: RFA (n=36) -Frequency: Continuous, 5-mm active tip electrode at 80 degrees C for 90 seconds -Target … 40 A: RFA (n=20) -Frequency: Continuous, 5-mm active tip electrode at 85 degrees C for 60 seconds -Target … 81 A: RFA (n=40) -Frequency: Continuous, 5-mm active tip electrode at 80 degrees C for 60 seconds -Target … Facet nerve block (n=44) - Target: L1 to L4, medial articular branch of the posterior primary ramus, … Facet nerve block, 0.5 to 1.0 mL steroid (n=60) Target: L1 to L4 levels and l5 dorsal ramus Guidance

34. Hi Les, (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/rtc-design-principles_research.pdf
    January 01, 2009 - Construct a flow diagram to show its key elements, including target population, prior tests, and the … all potential changes in outcomes, clinical experts involved in the diagnosis and management of the target … patient outcomes and construct a flow diagram to map out the key elements of this trial, including the target … Display Existing Test Strategy The first step when constructing the flow diagram is to display the target … Prior tests that are common to each pathway can be listed with the definition of the target population

35. Protocol for Quantitative Assessment of Benefit and Harm analysis of Aspirin for primary prevention (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research.pdf
    February 01, 2014 - We focused on observational studies that were most applicable to our target population—aged 50 to 84 … We defined the target population as age 50 to 84 years, living in the United States without evidence … This may be particularly true when the target population is dissimilar from the trial population with … Thus, although the target estimates researchers commonly use differ markedly between the NNT and NNH … We assumed that the treatment effects from trials applied to our target populations.

36. Hunt_Panel_3 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/hunt_panel_3.pdf
    January 01, 2010 - Mobile Web use is increasing most rapidly in households with incomes <$30,000/yr • New opportunities to target

37. Ch 5-User-Guide-To-Ocer 130129 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
    January 01, 2012 - example, that researchers linked a registry for a device and a separate clinical registry for the target … from different databases: (1) residual confounding and (2) generalizability (a concept related to target … In the previous example study of device and clinical registries linked to Medicare, the finite target … Therefore, patients who are not in good general condition due to severe target disease or comorbidities … Estimating causal parameters without target populations.

38. Medical-Evidence-Communication Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-evidence-communication_research-protocol.pdf
    July 31, 2012 - various contents and formats that increases the likelihood that it will be understood and used by the target … various ways of communicating uncertainty associated with health and health care evidence to different target … They use various techniques to communicate evidence so that target audiences can understand it better … Intermediate outcomes are applicable to all target audiences. … Possible moderators of interest for all key questions include: risk of bias, study size, and target

39. Phenylketonuria Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/phenylketonuria_executive.pdf
    February 01, 2012 - However, there is some variation in the target Phe level among clinics and across countries.3,4 In … The primary target health outcome is maintenance of cognition; secondary outcomes include increasing … Phe levels were reduced by at least 30 percent (the usual research target) in up to half of treated … Although the current literature does not provide evidence for effectiveness in all target patients, … The mechanism by which LNAAs may work should be clarified, as should the optimal target population

40. Cancer-Anemia-Update Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_executive.pdf
    April 01, 2013 - Health-Related Quality of Life Treating to high target hemoglobin levels (greater than 12 g/dL) was … of the evidence included here was obtained under treatment protocols that used higher baseline and target … While it is possible that adverse event rates might be somewhat different with lower baseline and target