-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/bladder-cancer-non-muscle-invasive_disposition-comments.pdf
October 27, 2015 - Results were
stratified for patients with
symptoms and for
surveillance. … Page 75 – throughout the review the
authors refer to biomarkers studies tested
in patients with “symptoms … we were
referring to testing for initial
diagnosis of bladder cancer
in patients with signs or
symptoms … We Revised to be clearer
that evaluation of symptoms
was in patients without a
prior diagnosis of … Results were
presented separately for
evaluation of symptoms (no
prior diagnosis) and
surveillance
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-nonsurgical-therapies_research-protocol.pdf
February 22, 2012 - endobronchial
obstruction from primary or recurrent stage IIIa, IIIb, or IV lung tumors, manifested by
symptoms … Among
patients with stage IIIa disease, treatment may be undertaken to relieve symptoms, to improve … Endobronchial BT also may be an option for
patients in whom EBRT fails to relieve symptoms or for those … Intermediate outcomes: Local control, lung function (e.g., forced expiratory volume
1), pulmonary symptoms … Intermediate outcomes, such as local control,
recurrence, lung function (e.g., FEV1), pulmonary symptoms
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1306.pdf
October 01, 2014 - blocking the GR-II
receptor might prevent excessive cortisol activity, potentially relieving PMD symptoms … Experts also thought that if DBS were effective at controlling MDD
symptoms, it might decrease the … dosages lower
than those used for anesthesia.31 Data from these trials suggested that depressive symptoms … Course of improvement in depressive
symptoms to a single intravenous infusion of
ketamine vs add-on … Rapid decrease in depressive symptoms
with an N-methyl-d-aspartate antagonist in ECT-
resistant major
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_executive.pdf
November 01, 2012 - , 2)
(KQs 3, 4)
Intermediate Outcomes
• Time in ED (hours)
• Vital signs
• Recurrence of severe
symptoms … Analytic Framework
KQ = Key Question; ED = emergency department
of severe symptoms, or return ED visits … Extrapyramidal Symptoms
Seven studies reported extrapyramidal symptoms as a
result of treatment. … We conducted a post hoc mixed-treatment analysis of
15 studies that reported akathisia symptoms as … The odds of
experiencing akathisia symptoms following administration
of these drugs were in the range
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-brain-injury_executive.pdf
April 01, 2011 - Risk factors for depressive symptoms
after mild-to-moderate traumatic brain injury. … Affective symptoms in the
chronic stage of traumatic brain injury: a study of married
couples. … Are there symptoms
that are specific for depressed mood in patients with traumatic
brain injury? … Posttraumatic
stress disorder symptoms during the first six months after
traumatic brain injury. … Attention and
depressive symptoms in chronic phase after traumatic brain
injury.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-cough_executive.pdf
March 01, 2014 - focus on curing
the underlying etiology (e.g., bacterial bronchitis or
pneumonia) or suppressing symptoms … reaction
• Drowsiness
• Headache
• Chest pain
• Dizziness
• Rash
• Others
Adverse Events
• Cough symptoms … The following
outcomes were considered: cough symptoms and severity,
complications related to coughing … data
on changes in these measures over time associated with
treatment (or no treatment) of cough symptoms … More consistent
reporting of patient characteristics such as age, underlying
etiology, duration of symptoms
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
April 01, 2015 - This results in
classic symptoms associated with MS. … as many women
as men are affected, and diagnosis usually
occurs between the ages of 20 and 50.1
Symptoms … Neurologic symptoms of a
relapse typically develop over a course
of days, stabilize, and spontaneously … CIS involves neurologic
symptoms such as vision loss, numbness, or weakness
that last at least 24 hours … The most commonly
reported adverse events were injection site reactions,
flulike symptoms, depression
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-anxiety-children_0.pdf
October 01, 2018 - DA was produced as cards containing information on issues that drive treatment decisions (effect
on symptoms … psychologists, the 5 topics usually discussed when a treatment is chosen
were: “reduction in anxiety symptoms … title/introduction card, and the remaining five displayed content relating to reduction in anxiety
symptoms … Reduction in anxiety symptoms and improvement in day-day function were
displayed with a scale of 1-4 … The scales for symptoms and improvement in day-to-day function were based off data
from the original
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia_horizon-scan-high_impact-1306-revised.pdf
July 09, 2013 - Symptoms are typically not evident in early, preclinical AD; however,
ES-3
toxic changes begin … biologics, and alternative
or complementary interventions that modify the disease or better manage symptoms … disease’s early stages, is not straightforward, especially because many other conditions can
cause symptoms … currently available
pharmacotherapies indicated for use in patients with AD treat only the disease symptoms … of mild to moderate AD, and memantine is approved to treat the symptoms of moderate
to severe AD.43
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cerebral-palsy-feeding_research-protocol.pdf
June 12, 2012 - life, as well as
contribute to comorbidities including respiratory conditions and gastrointestinal symptoms … problems, asthma or other
respiratory markers
o Pain/comfort
o Diarrhea
o Other gastrointestinal symptoms … respiratory problems, asthma, or other
respiratory markers
o Pain/comfort
o Other gastrointestinal symptoms … respiratory problems, asthma, or other
respiratory markers
o Pain/comfort
o Other gastrointestinal symptoms … respiratory problems, asthma, or other
respiratory markers
o Pain/comfort
o Other gastrointestinal symptoms
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_surveillance.pdf
October 29, 2012 - CER # 48:
Hematopoietic Stem-Cell Transplantation in the Pediatric
Population
Original release date:
February 01, 2012
Surveillance Report:
October 29, 2012
Key Findings:
• KQ1, 2, 3, 4, 5 and 6 up to date
• Expert opinion: conclusions still valid
• There are no new significant safety co…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-protocol-2021_0.pdf
January 01, 2021 - illustrates how PTSD treatments may be associated with
health and functional outcomes including PTSD symptoms … categorized as “Controls”
None
Outcomes • Any overall PTSD outcome • Studies reporting only individual symptoms … Symptoms and subjective quality of life in post-
traumatic stress disorder: a longitudinal study. … Duration of PTSD symptoms
e. % Active duty military
f. % Veteran
g. % Community
h.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd4-final-protocol.pdf
October 01, 2022 - illustrates how PTSD treatments may be associated with health
and functional outcomes including PTSD symptoms … categorized as
“Controls”
None
Outcomes • Any overall PTSD outcome • Studies reporting only individual symptoms … Symptoms and subjective quality of life in post-traumatic
stress disorder: a longitudinal study. … Duration of PTSD symptoms
e. % Active duty military
f. % Veteran
g. % Community
h.
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis_hi_impact.pdf
January 01, 2014 - RA therapies with improved efficacy, tolerability, and convenience that can
effectively control RA symptoms … cautiously optimistic about the potential of MSCs to improve patient health outcomes by relieving
symptoms … In one study, patients with osteoarthritis (OA) of the knee (Outerbridge grades I through IV and
symptoms … painkillers, corticosteroid injections, or visco-supplementation.
40
In patients with persistent symptoms … investigators reported that tofacitinib showed statistically significant reductions in signs and
symptoms
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-immunotherapy-2010_disposition-comments.pdf
January 01, 2010 - Only when subgroup analyses
were performed on the data, was it possible to
show an effect on symptoms … Specifically for the primary outcome of rhinoconjuntivitis symptoms
scores, the Skoner article (as demonstrated … Furthermore, a 15%
reduction in symptoms in the “active” treatment
group would not be considered clinically … it is stated that the
strength of evidence is high that subcutaneous
immunotherapy improves asthma symptoms … This particular study was assessed for
rhinoconjunctivitis symptoms as follows: medium risk of bias,
-
effectivehealthcare.ahrq.gov/sites/default/files/web-based_osheroff_respondent.pdf
January 01, 2009 - treatments
(based
on
flow)
“Caregiving
responsibilities
include
monitoring
symptoms
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0264_01-14-2008.pdf
January 01, 2008 - juvenile idiopathic arthritis, do drug therapies differ in their ability to
reduce patient-reported symptoms
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0663-131114.pdf
April 10, 2013 - interventions, somatic
treatments, combinations of these, and placebo/sham
Outcome(s): Improvement in symptoms
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer18-heart-disease-ace-inhibitor-arb-executive.pdf
October 01, 2009 - with a stent or coronary artery bypass
surgery, degree and location of lesion, presence and
pattern of symptoms … ARB telmisartan was relatively well tolerated, with
only a statistically higher risk of hypotension symptoms … with a stent or coronary
artery bypass surgery, degree and location of lesion, presence and pattern of symptoms … Presence and pattern Insufficient • The impact of ACE inhibitors, ARBs, and their
of symptoms combination … in subjects with different presence and
pattern of angina symptoms cannot be determined at this
time
-
effectivehealthcare.ahrq.gov/sites/default/files/s96.pdf
October 01, 2007 - using the Medical Dictio-
nary for Regulatory Activities (MeDRA) to describe the
following: diagnoses, symptoms … Surveillance be-
gins with patient presentation at emergency department for
treatment of ADE-related symptoms … cause of ED visits.27,28 Second, polyp-
harmacy can complicate attribution of a patient’s clinical
symptoms … the
treating physician recognizes an association between a drug’s
effects and a patient’s presenting symptoms … NEISS-CADES addresses a primary
outcome of ADEs—manifestation of patient symptoms and
subsequent health-seeking