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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/bereaved-persons-protocol.pdf
    June 01, 2023 - and included in the ICD-11 in 20186 and classified as a formal disorder in the DSM-V TR in 2022.7 Symptoms … be at risk for prolonged grief disorder (selected approach), and c) individuals who have signs or symptoms … ; severity of grief disorder; continued meeting grief disorder criteria; depression symptoms; quality … The influence of symptoms of prolonged grief disorder, depression, and anxiety on quality of life among … Inventory of Complicated Grief: a scale to measure maladaptive symptoms of loss.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children_research-protocol.pdf
    June 04, 2010 - but common side effects include dry mouth, sedation, extrapyramidal side effects (EPS; a cluster of symptoms … Off-label prescriptions are used in younger children for behavioral symptoms (e.g., irritability and … first and second generation antipsychotics for treating disorder/illness specific and nonspecific symptoms … The following symptoms are included for each disorder or illness: 1) PDDs: qualitative impairment … mood disturbance, psychotic features; 4) Schizophrenia and related psychoses: positive and negative symptoms
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0648-140819.pdf
    June 24, 2014 - some studies indicate that diagnosis in primary care is often based primarily on clinical signs and symptoms … The diagnostic accuracy of clinical signs and symptoms is uncertain. § Gout is treated by both nonpharmacologic
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ocd-protocol.pdf
    August 15, 2023 - “If screening suggests [obsessive compulsive] symptoms may be present, clinicians should fully evaluate … criteria for and specific treatment of PANS/PANDAS is outside the scope of this review, given that OCD symptoms … diagnosis or treatment of PANS/PANDAS; rather, the review should maintain its focus on youth with symptoms … OCD and/or other conditions which may be either be comorbid with OCD or may present with similar symptoms … tic disorders) o Diagnosis during COVID-19 pandemic (as defined by study authors) o Duration of symptoms
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
    March 01, 2018 - Transparency of Reporting Requirements for Studies Evaluating the Effectiveness of Treatment Options for Symptoms … Transparency of Reporting Requirements for Studies Evaluating the Effectiveness of Treatment Options for Symptoms … Transparency of Reporting Requirements for Studies Evaluating the Effectiveness of Treatment Options for Symptoms … Using a systematic review on the effectiveness of treatment options for symptoms of diabetic peripheral … Pregabalin relieves symptoms of painful diabetic neuropathy: a randomized controlled trial.
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/abnormal-uterine-bleeding_executive.pdf
    March 01, 2013 - variation) within 2 to 20 days • Duration of flow from 4 to 8 days • Blood loss volume from 5 to 80 ml Symptoms … Both biologic and self-reported symptoms of bleeding severity were improved. … Overall, decision aids did not result in choices that influence disease symptoms in directly measurable … The studies in this review reported harms profiles for common symptoms similar to 9 package insert … and contraceptive or fertility desires, as well as potentially improving other symptoms like menstrual
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/bladder-cancer-non-muscle-invasive_executive.pdf
    October 01, 2015 - – For evaluation of symptoms: Sensitivity was 0.47 (95% CI, 0.33 to 0.61) and specificity 0.93 (95% … – For evaluation of symptoms: Sensitivity was 0.76 (95% CI, 0.61 to 0.87) and specificity 0.53 (95% … – For evaluation of symptoms: Sensitivity was 0.73 (95% CI, 0.50 to 0.88) and specificity 0.95 (95% … Diagnostic Accuracy: Patient Characteristics or Presenting Signs or Symptoms For this Key Question … • BCG alone was associated with increased risk of constitutional symptoms (1 trial; RR, 1.63; 95%
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/catd-protocol-draft_0.pdf
    November 02, 2018 - and is costly to families and society.4 Agitation, aggression and other behavioral and psychological symptoms … These symptoms may imperil the safety of the patient and others, and often are highly distressing to … Data reported on function was limited and these treatments did not improve behavioral symptoms. … Since this outcome eliminated, drugs targeted to these symptoms should be eliminated. … Assessment and management of behavioral and psychological symptoms of dementia.
  9. effectivehealthcare.ahrq.gov/sites/default/files/devdelays_adhd_autism_hi_impact.pdf
    January 01, 2012 - However, experts opined that it is not clear whether other symptoms of ASDs would benefit from this … Suspected ASD can also sometimes mimic bipolar disorder symptoms. … However, the experts noted that it is not clear if other symptoms of ASDs would benefit from this type … ASDs and bipolar disorder can exhibit similar signs and symptoms in children. fMRI would be intended … as an adjunct to assess suspected signs and symptoms suggestive of either ASD or bipolar disorder
  10. effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1406.pdf
    February 01, 2015 - Biomarkers are typically not evident in preclinical AD, and behavioral symptoms are often dismissed … continues to track several interventions and diagnostics for treating dementia, AD, and associated symptoms … etiology, researchers hypothesize that this intervention may both alleviate AD-related cognitive symptoms … National Institute on Aging, approved AD medications treat disease symptoms only, including progressive … a phase II/III trial investigating intranasal administration of Humulin R for treating cognitive symptoms
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/standardized-library-depression-white-paper.pdf
    May 01, 2020 - Of note, several outcome measures focus on change over time, such as improvement in depressive symptoms … Clinical Response Improvement in Depressive Symptoms – Remission Patient age 18 or older with a … A-2 OMF CATEGORY OUTCOME MEASURE DEFINITION Clinical Response Improvement in Depressive Symptoms … A-3 OMF CATEGORY OUTCOME MEASURE DEFINITION Clinical Response Worsening in Depressive Symptoms
  12. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/standardized-library-depression-white-paper.pdf
    May 01, 2020 - Of note, several outcome measures focus on change over time, such as improvement in depressive symptoms … Clinical Response Improvement in Depressive Symptoms – Remission Patient age 18 or older with a … A-2 OMF CATEGORY OUTCOME MEASURE DEFINITION Clinical Response Improvement in Depressive Symptoms … A-3 OMF CATEGORY OUTCOME MEASURE DEFINITION Clinical Response Worsening in Depressive Symptoms
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/insomnia_clinician.pdf
    August 01, 2017 - Diagnostic criteria for insomnia disorder require that sleep symptoms cause clinically significant … basis (at least 3 nights per week for at least 3 months).1 Many treatments are available for insomnia symptoms … Possible respiratory depression in people with severe lung disease or sleep apnea �� Withdrawal symptoms … while not fully awake �� Sleep paralysis, hypnagogic or hypnopompic hallucinations, cataplexy-like symptoms
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0359_10-15-2010.pdf
    January 01, 2010 - Intervention(s): Disease-modifying therapies for delay of relapse and disability, treatments to address symptoms
  15. effectivehealthcare.ahrq.gov/products/prostatic-hyperplasia-medications/research-protocol
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-pharmacologic-treatment_research-protocol.pdf
    December 27, 2016 - edema reduce airflow intermittently, often in response to specific exposures, resulting in respiratory symptoms … Definition of Terms Asthma control: The degree to which the manifestations of asthma (symptoms, functional … Asthma control is determined by assessing the domains of impairment (patient self-reported symptoms, … not currently receiving controller therapy using the domains of impairment (patient self-reported symptoms … Controlled asthma: Minimal manifestations of asthma symptoms and functional impairments, as determined
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
    June 23, 2014 - mainly defined by the presence of manic or mixed episodes that last at least seven days, or by manic symptoms … The symptoms of mania or depression must be a major change from the person's normal behavior. … Once stable, the goal progresses to reduction of subthreshold symptoms and relapse prevention. … Schizoaffective disorder is distinguished by higher psychotic symptoms than bipolar disorder. … Diagnosing bipolar disorder is challenging because of the lack of specificity of many of the symptoms
  18. effectivehealthcare.ahrq.gov/sites/default/files/mcda-ijzerman.pdf
    January 01, 2011 - Integrating stakeholder preferences in comparative effectiveness research using multi-criteria decision analysis (MCDA) and Conjoint Analysis (CA) Slide 1 Integrating stakeholder preferences in comparative effectiveness research using multi-criteria decision analysis (MCDA) and Conjoint Analysis (CA) Maarten J…
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-facilitating-implementation-pilot.pdf
    October 01, 2019 - Parents wanted information to assist in their understanding of the diagnosis, prognosis, symptoms, and … Available Data The EPC report demonstrated that parent training and education programs improved ADHD symptoms … adequate description of their curricula, and showed the curricula to be effective in reducing ADHD symptoms … In this specific example, we knew that parent education programs improve ADHD symptoms and are desired … brief psychoeducation program for parents of ADHD children: improvement of medication adherence and symptoms
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-260-improved-cancer-outcomes-executive-summary_0.pdf
    May 01, 2023 - Finally, among studies of the effects of nutrition interventions on symptoms, three medium-risk-of-bias … studies in dietary supplements reported mixed results for patient- reported symptoms.33 23, 43 One study … life,33 while another reported no benefit.23 Two studies reported mixed outcomes for patient-reported symptoms … carbohydrate drinks.28, 66 A third low-risk-of-bias study reported improvement in treatment tolerance and symptoms … One study reported on each of the following symptoms: quality of life, symptoms, and treatment tolerance

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