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Showing results for "substantial".

61. Disposition of Comments for Technical Brief 21, Management Strategies To Reduce Psychiatric Readmissions (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/psychiatric-readmissions_disposition-comments.pdf
    May 21, 2015 - #5 Key Informant Background Background p. 8, lines 8-13: “are a substantial problem. … For example, case managers cannot coordinate care easily if there are substantial administrative burdens … The statement in the Summary and Implications section that says “…despite substantial effort to research … (e.g., "At the same time, there has been a substantial effort to research this area as the amount of … is justified57,61,63,90 and whether the benefit (in terms of number of decreased hospital LOS) is substantial

62. GRADING THE STRENGTH OF A BODY OF EVIDENCE (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-strength_methods.pdf
    July 01, 2009 - Agency for Healthcare Research and Quality (AHRQ), produces substantial numbers of evidence reports … With substantial unexplained heterogeneity, however, EPCs should be appropriately cautious about estimating … Substantial variability does not necessarily render an estimate imprecise. … studies have less risk of bias than do randomized trials or that the available randomized trials have a substantial

63. Chicago-Area DEcIDE Center (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/off-label-use-research-priorities_research.pdf
    May 01, 2009 - frequent in these clinical areas, that such uses arise from diverse circumstances, and that there is substantial … prescribing data identified a high volume of off-label prescribing in the absence of good evidence for a substantial … Although we received substantial input from our technical expert panel, the framework we developed included … However, our sensitivity analysis indicated that the framework was quite robust to substantial changes … While past research has highlighted the substantial frequency of off-label use without good evidence

64. Methods Guide for Medical Test Reviews Chapter 9 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-performance_methods.pdf
    July 01, 2012 - However, there is large night-to-night variability in the measured AHI, and there is also substantial … The third option is potentially subject to substantial bias, which is especially difficult to interpret … alternative cutoffs did not affect the results or conclusions of the systematic review, but did require substantial … First, there is considerable night-to-night variability in the measured AHI, as well as substantial

65. Quantitative Synthesis: Chapter 4. Quantifying, Testing, and Exploring Statistical Heterogeneity (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-4.pdf
    July 01, 2019 - might not be important − 30%-60% = may represent moderate heterogeneity* − 50%-90% = may represent substantial … P value from the Chi2 test, or a confidence interval for I2) • Uncertainty in the value of I2 is substantial

66. Case-Management Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/case-management_executive.pdf
    January 01, 2013 - In recognition of the substantial heterogeneity of purposes, approaches, and populations included … suggests that a high-intensity CM intervention sustained over a period of several years can produce a substantial … There is a substantial evidence base about CM for complex chronic diseases.

67. McCullough (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/mccullough.pdf
    January 01, 2011 - McCullough Slide  1: An Ethical Framework for Supporting  Shared Decision Making  When Clinical Evidence is Low Laurence B. McCullough, Ph.D. Dalton Tomlin Chair in Medical Ethics and Health Policy Associate Director for Education Center for Medical Ethics and …

68. Disposition of Comments for CER 201 Effectiveness of Indoor Allergen Reduction in the Management of Asthma (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-201-indoor-allergen-asthma-disposition-comments.pdf
    February 15, 2018 - Academy leadership notes that the manuscript is well written, the product of a substantial amount of … We have included substantial data about allergen reduction, when available, in the Strength of Evidence … We have included substantial data about allergen reduction, when available, in the Strength of Evidence … We agree that there are substantial research gaps for many of the interventions and outcomes, and we … We agree that there are many substantial challenges to conducting research in this field.

69. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-provider-adherence_research-protocol.pdf
    March 02, 2012 - A value greater than 50% will be considered to have substantial statistical heterogeneity. … If we find substantial heterogeneity, we will attempt to determine potential reasons by conducting metaregression … Urban minority children with asthma: substantial morbidity, compromised quality and access to specialists

70. Cad-Pci-Bypass Surveillance (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_surveillance.pdf
    May 01, 2013 - A2 Substantial harm: A pivotal trial or systematic review (or guidelines) whose results called into … • If we found substantial new evidence that might change the CER conclusion, and/or a majority of

71. DRN: Report 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-safety_research.pdf
    July 01, 2009 - AHRQ continues to provide substantial feedback on the network design. … Without strong support from stakeholders, implementation and maintenance of a DRN will be a substantial … The risks of participation for data owners are substantial and must be mitigated in the development … Effective Health Care Research Report Number 13 54 Substantial network design challenges arise … The work of transforming a new data resource to the common model is non-trivial and requires substantial

72. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0334_08-04-2010.pdf
    January 01, 2010 - Effective Health Care Topic Number: 0285 Document Completion Date: 3-22-11 1 Results of Topic Selection Process & Next Steps  Pharmacogenetic testing for CYP2C19 variants for guiding antiplatelet treatment will go forward for refinement as a systematic review. The scope of this topic, including p…

73. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0371_11-23-2010.pdf
    January 01, 2010 - Effective Health Care Topic Number: 0313 Document Completion Date: 12-12-11 1 Results of Topic Selection Process & Next Steps  Outcomes of serious mental illness will go forward for refinement as a systematic review. The scope of this topic, including populations, interventions, comparators, and…

74. Public-Reporting-Quality-Improvement Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/public-reporting-quality-improvement_executive.pdf
    July 01, 2012 - Introduction A substantial amount of research exists demonstrating that health care frequently fails … continuing commitments to transparency and patient-centered health care are likely to contribute to substantial … information contained in public reports is accurate and useful for patient selection, even if there is a substantial

75. Disposition of Comments_Blood-Based Tests for Multiple Cancer Screening: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-disposition-comments.pdf
    May 14, 2025 - Consider adding, "...when certain criteria, such as no substantial changes to the test, are met." … absence of cancer screening.”6 Cancers found early are generally easier to treat, and there is a substantial … deaths occur due to cancer types that are not targeted by current screening methods in the US12 A substantial … Additionally, DHA's substantial requirements for evidence review by its Joint Laboratory Working Group

76. Methods Guide for Medical Test Reviews Chapter 12 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-prognostic_methods.pdf
    July 01, 2012 - Selecting Studies and Assessing Quality Previous reviews of prognostic indicators have demonstrated substantial

77. A Randomized Trial of Epidural Glucocorticoid Injections for Spinal Stenosis: A Brief Summary of Findings for Clinicians (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/glucocorticoid-injections_clinician.pdf
    June 01, 2016 - pro- portions of patients with at least minimal clinically meaningful improvement (≥30%) and with substantial

78. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_executive.pdf
    May 01, 2010 - Examination of the dosing information on outlier cases indicated substantial variation in the dose of … There was substantial variation in the dose and timing of rFVIIa provided making it difficult to assess … transplantation (0.3 percent) and prostatectomy (0.0 percent). rFVIIa is used in patients who experience substantial

79. Underperformance of Contemporary Phase III Oncology Trials and Strategies for Improvement | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/grant-manuscripts/underperformance-abstract

80. Noninvasive, Nonpharmacological Treatment for Chronic Pain (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharma-treatment-pain_research-protocol-amended.pdf
    September 20, 2017 - In addition, it appears that there is substantial overlap across systematic reviews regarding included … Most comments noted that there was substantial heterogeneity within the included chronic pain conditions … • Regarding exercise, we realize that there is likely substantial diversity in the types and delivery … Systematic reviews may be excluded based on currency or relevance (e.g., if there is a substantial … Large/substantial effects were defined as greater than moderate.