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Total Results: 965 records

Showing results for "substantial".

421. Renal-Artery-Stenosis Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_surveillance.pdf
     June 01, 2012 - conclusion, then we classified the CER conclusion as possibly out of date. 4 • If we found substantial … or recent textbook (e.g., UpToDate): • Opposing findings (e.g., effective vs. ineffective) – A1 • Substantial

422. Research White Paper Managing Missing Data in Patient Registries Addendum Registries for Evaluating Patient Outcomes Third Edition (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
     February 01, 2018 - Because missing data can have a substantial impact on registry findings, as well as any clinical or … forward, or best observation carried forward.22 Single imputation methods may introduce bias, sometimes substantial

423. Comparative Effectiveness of Pain Management Interventions for Hip Fracture | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/hip-fracture-pain/research-protocol

424. Disposition of Comments for CER 211: Drug Therapy for Early Rheumatoid Arthritis: A Systematic Review Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-211-rheumatoid-arthritis-disposition-comments.pdf
     December 20, 2018 - Within FDA approved dose ranges, are there substantial dose variations across studies? … Within FDA-approved ranges, there were no substantial variations in average dosages. … Given this targeted scope of the Draft Report, there are substantial differences in the body of evidence

425. Disposition of Comments_CER 231 Care Interventions for People Living With Dementia and Their Caregivers (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-231-dementia-care-interventions-disposition-comments.pdf
     July 31, 2020 - For intervention categories with more substantial analytic sets, we also provided further detail in … my other comments related to inclusion of deeper insight into those interventions that have seen substantial … related to the current layout of the document and tables, which make it difficult to synthesize the substantial

426. Disposition of Comments Report for Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
     September 25, 2013 - The subjectivity in assessing SOE is evident in the substantial discrepancies among the peer reviewers … Introduction/ Background ES-1 The question of identifying the optimal antiplatelet therapy may also carry substantial … Low levels of platelet aggregation are consistent with a substantial effect of the drug – these levels

427. Microsoft Word - Comp Eff 10.doc (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-2007_research-2007-1.pdf
     January 01, 2007 - being the number one attributable risk factor for death throughout the world, hypertension results in substantial … suboptimal blood pressure is the number one attributable risk factor for death throughout the world.2 Substantial … single agent, this outcome seemed to represent a reasonable comparison that was not confounded by substantial

428. Disposition of Comments CER 185 Tympanostomy Tubes in Children With Otitis Media (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-disposition.pdf
     May 05, 2017 - Given the small total number of studies (with a single NRCS) and substantial heterogeneity of reported … We did not quantitatively pool the results, primarily because of the small number of studies and substantial

429. Disposition of Comments CER 185 Tympanostomy Tubes in Children With Otitis Media (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/tympanostomy-tubes-disposition.pdf
     May 05, 2017 - Given the small total number of studies (with a single NRCS) and substantial heterogeneity of reported … We did not quantitatively pool the results, primarily because of the small number of studies and substantial

430. Epilepsy-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
     August 01, 2012 - A2 Substantial harm: A pivotal trial or systematic review (or guidelines) whose results called into … • If we found substantial new evidence that might change the CER conclusion, and/or a majority of

431. Epilepsy-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
     August 01, 2012 - A2 Substantial harm: A pivotal trial or systematic review (or guidelines) whose results called into … • If we found substantial new evidence that might change the CER conclusion, and/or a majority of

432. ASSESSING THE QUALITY OF INCLUDED STUDIES (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/assessing-the-risk-of-bias_draft-report.pdf
     June 02, 2011 - have grown increasingly concerned about the practice of ghost authoring (i.e., primary authors or substantial … contributors are not identified) or guest authoring (i.e., one or more identified authors are not substantial … their reviewers made these judgments, but such the fact remains that these approaches can suffer from substantial

433. Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/thromboembolism-update-disposition.pdf
     June 22, 2017 - Without evidence of substantial differences in underlying VTE rates between existing studies and clinical … fracture with minimal blood loss, to an intramedullary nailing of a complex comminuted fracture with substantial

434. Methods Guide for Comparative Effectiveness Reviews_Inclusion of Nonrandomized Studies of Interventions in Systematic Reviews of Intervention Effectiveness: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
     September 01, 2022 - Substantial heterogeneity exists in how NRSIs are classified and described. … Additionally, there may be a substantial amount of missing data when sources such as patient-generated … We suggest that, unless there is substantial confidence in the NRSI design and analytic methods, their

435. Methods Guide for Comparative Effectiveness Reviews_Inclusion of Nonrandomized Studies of Interventions in Systematic Reviews of Intervention Effectiveness: An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
     September 01, 2022 - Substantial heterogeneity exists in how NRSIs are classified and described. … Additionally, there may be a substantial amount of missing data when sources such as patient-generated … We suggest that, unless there is substantial confidence in the NRSI design and analytic methods, their

436. Comparative Effectiveness Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_appendixes.pdf
     January 01, 2006 - Is there evidence of a substantial effort to search for all relevant research? … (3) Is there evidence of a substantial effort to search for all relevant research? … (3) Is there evidence of a substantial effort to search for all relevant research? … (3) Is there evidence of a substantial effort to search for all relevant research? … (3) Is there evidence of a substantial effort to search for all relevant research?

437. Disposition of Comments: Comparative Effectiveness Review 235_Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: An Update of the PTSD-Repository Evidence Base (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-comments.pdf
     November 04, 2020 - Substantial symptom improvement? Not brief enough. … TEP 9 General Comments The utility of this type of report is substantial for identifying holes in

438. Evidence-based Practice Center Systematic Review Protocol: Management of High-Need, High-Cost Patients: A Realist and Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/mgmt-hnhc-patients-protocol.pdf
     November 07, 2019 - Although HNHC patients represent a small proportion of the patient population, they account for a substantial … If the volume of evidence is large, we may focus the SOE grading on outcomes of substantial importance

439. Disposition of Comments_Comparative Effectiveness Review No. 262_Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings: Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-disposition-comments.pdf
     November 07, 2023 - additional information to the overall body of literature, we do not think it is appropriate to provide substantial … Also, considerable heterogeneity seems less pronounced than substantial heterogeneity yet is listed

440. The Refinement of Topics for Systematic Reviews: Lessons and Recommendations From the Effective Health Care Program (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-topic-refinement_methods.pdf
     January 01, 2013 - Other topics may be less clear or complete and require more substantial refinement. … workgroup members had experience in topic refinement across various EPCs, and the Project Officer had substantial