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Total Results: 965 records

Showing results for "substantial".

241. Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1512.pdf
     December 01, 2015 - According to most experts, metabolic surgery represents a substantial disruption to how most patients … If insurance coverage becomes widely available and substantial patient demand develops, the programs … Most experts thought that metabolic surgery would represent a substantial disruption to how patients … scenarios would take years to play out.”69 Several experts noted that metabolic surgery would be a substantial … On one hand, several experts thought metabolic surgery could offer a substantial improvement in diabetes

242. Dispostion of Comments Report for Screening for Hepatitis C Virus Infection in Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_disposition-comments.pdf
     November 27, 2012 - a limited window available to fill in evidence gaps before screening becomes irrelevant because a substantial … currently a significant source of *incident* cases of chronic HCV, this risk factor accounts for a substantial … In addition, a substantial number of HCV-infected individuals with fibrosis may have persistently normal … 6 Results I would strongly recommend collaboration with large health care organizations that have substantial … This highlights the risks of drawing premature conclusions in an area undergoing substantial transformation

243. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/disabilities-quality-improvement-outcomes_research-protocol.pdf
     August 03, 2011 - Social Security Administration (SSA) Inability to engage in any substantial gainful activity by

244. Autism-Adolescents Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_executive.pdf
     August 01, 2012 - Thus there was substantial variability and limited information on developmental, cognitive, and behavioral … trials is notable in all categories of intervention, but especially so in medical interventions, where substantial … Substantial, foundational research should be done to identify and validate outcome measures in the

245. Renal-Cancer Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_research-protocol.pdf
     April 20, 2015 - A value greater than 50% will be considered to have substantial statistical heterogeneity. … If we find substantial heterogeneity, we will attempt to determine potential reasons by conducting meta-regression … When between event rates are between 5-10%, substantial differences between the N of two arms, or when

246. Juvenile-Arthritis-Dmards Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_surveillance.pdf
     March 14, 2013 - A2 Substantial harm: A pivotal trial or systematic review (or guidelines) whose results called into … conclusion, then we classified the CER conclusion as possibly out of date. 3 • If we found substantial … response/ intolerance to >/= 1 DMARD HRQOL 10 months During the open-label period (A) there were substantial

247. Juvenile-Arthritis-Dmards Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_surveillance.pdf
     March 14, 2013 - A2 Substantial harm: A pivotal trial or systematic review (or guidelines) whose results called into … conclusion, then we classified the CER conclusion as possibly out of date. 3 • If we found substantial … response/ intolerance to >/= 1 DMARD HRQOL 10 months During the open-label period (A) there were substantial

248. Microsoft Word - Comparative_Effectiveness_Research_Review_Disposition_of_Comments_Report_Final_120710_refs_delinked1.docx (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_disposition-comments.pdf
     November 01, 2010 - As discussed in the review, the only good or fair studies found effects far less substantial than what … By using an overly narrow definition of science and excluding a very substantial body of scientific … I wouldn't make substantial changes. I identified no major discrepancies. … Online: Month XX, 20XX 44 Section Comment Response Methods Later, it is stated that, “while substantial … I believe it is premature to state that substantial proportions of children do not demonstrate robust

249. Adverse Events Associated with COVID-19 Pharmaceutical Treatments (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments.pdf
     December 23, 2023 - Adverse Events Associated with COVID-19 Pharmaceutical Treatments Evidence-based Practice Center Rapid Review Protocol Project Title: Adverse Events Associated with COVID-19 Pharmaceutical Treatments I. Background and Objectives for the Systematic Review The Public Readiness and Emergency Preparedness A…

250. Executive Summary_Systematic Review: Mental Health and Occupational Stress in the Emergency Medical Services and 911 Workforces (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-911-workforce-mental-health-executive-summary.pdf
     February 01, 2025 - severity of mental health and occupational stress issues in the EMS and telecommunicator workforces is substantial

251. Mental-Illness-Heart Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_executive.pdf
     April 01, 2013 - Serious mental illness (SMI) is defined generally as a major mental or behavioral disorder, causing substantial … Behavioral interventions focusing on weight loss or diabetes management have no substantial effects

252. Lung-Cancer-Nonsurgical-Therapies Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_executive.pdf
     June 01, 2013 - radiotherapy procedures listed above are time intensive, require significant training, and necessitate substantial … However, a substantial subset of stage I NSCLC patients exists for whom surgery is contraindicated … Alternatives to surgery are important to health care providers, patients, and policymakers, given the substantial … proton beam radiotherapy; RFA = radiofrequency ablation; SBRT = stereotactic body radiotherapy 18 substantial

253. Living Systematic Reviews: Practical Considerations for the Agency for Healthcare Research and Quality Evidence-based Practice Center Program (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/practical-considerations.pdf
     March 01, 2022 - included from the successive screenings prompted the review team to rethink their analytic approach, substantial

254. Towards a Framework for Communicating Confidence in Methodological Recommendations for Systematic Reviews and Meta-Analyses (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methodological-recommendations-framework-communications_research.pdf
     September 01, 2013 - Thus, there is substantial variation in terms of evidentiary strength. … included in these data will differ. 17 no difference in the accuracy of data extraction, but a substantial … Recommendations that require substantial expertise or considerable resources will, of course, be more … probably feasible for systematic reviews with adequate funding, or even for unfunded reviews with substantial

255. Technical Brief 16 Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/advanced-care-decision-aids_disposition-comments.pdf
     July 29, 2014 - Technical Brief 16 Disposition of Comments Report Technical Brief Disposition of Comments Report Research Review Title: Decision Aids for Advance Care Planning Draft review available for public comment from February 12, 2014 to March 11, 2014. Research Review Citation: Butler M, Ratner E, McCreedy …

256. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_executive.pdf
     September 01, 2011 - Layout 1 Background Major depressive disorder (MDD) is common and costly. Over the course of a year, between 13.1 million and 14.2 million people will experience MDD. Approximately half of these people seek help for this condition, and only 20 percent of those receive adequate treatment. For those who do initiate tr…

257. Medical Therapies for Children With Autism Spectrum Disorder—An Updaterum Disorder--An Update (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-medical-disposition.pdf
     May 26, 2017 - to perform an expert review, I have not dwelled on typos or minor errors but instead focus on more substantial … This is a substantial change and could mean that smaller studies prior to 2010 were never captured;

258. Stem-Cell-Children Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_surveillance.pdf
     October 29, 2012 - conclusion, then we classified the CER conclusion as possibly out of date. 4 • If we found substantial … or recent textbook (e.g., UpToDate): • Opposing findings (e.g., effective vs. ineffective) – A1 • Substantial

259. Restless-Legs Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs_research-protocol.pdf
     December 16, 2011 - www.effectivehealthcare.ahrq.gov Published Online: December 16, 2011 3 Controversy and Uncertainty Clinicians face substantial …  Long-term benefits and harms of treatment: Substantial uncertainty exists about the long-term

260. Effectiveness of Screening and Treatment of Subclinical Hypothyroidism or Hyperthyroidism (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypothyroidism-hyperthyroidism-screening-treatment_disposition-comments.pdf
     February 01, 2012 - I would say the best study suggests a substantial increase in CV risk with subclinical hypothyroidism … pessimism is warranted without better data: it is possible that the population attributable risk is substantial