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Total Results: 965 records

Showing results for "substantial".

201. Evidence-based Practice Center Systematic Review Protocol - Management of Infantile Epilepsies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-disposition-comments.pdf
     October 25, 2022 - Uncontrolled seizures in children 1 to 36 months old have serious short-term health risks and may lead to substantial … cross sectional European collaborative outcomes study on several hundred patients will include a substantial

202. Antiplatelet-Treatment Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_executive.pdf
     September 01, 2013 - There was also substantial risk of selective outcome reporting for outcomes other than MACE. … 11 did not report statistically significant results and produced relatively wide CIs, indicating substantial … However, CIs were extremely wide and overlapping, suggesting that there is substantial uncertainty … However, the evidence is weakened by a substantial concern about selective reporting, publication bias … Future Research This review identified substantial gaps in the literature on genetic testing for CYP2C19

203. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_executive.pdf
     April 01, 2011 - children receiving intensive intervention demonstrate rapid gains, and many children continue to display substantial … Participants typically had substantial impairment or delay, but some children had less early cognitive … This lack of comparison groups presents substantial challenges for assessing effectiveness at a population … In sum, while some therapies hold promise and warrant further study, substantial needs exist for continuing

204. Disposition of Comments for CER 182 Glasgow Coma Scale (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/field-triage-glascow-disposition-170415.pdf
     January 12, 2017 - Further, there are substantial gaps between some points where an ROC curve extrapolates portions of … decision-making really does not exist (e.g., tGCS cut points of 3.5 or 14.5), but yet nevertheless contributes substantial … Investigators were not blinded to papers, as this would require substantial additional resources and … Peer Reviewer #3 General comments to authors Substantial copy-editing is needed.

205. Disposition of Comments: CER 227 Noninvasive Nonpharmacological Treatment for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-227-noninvasive-nonpharm-chronic-pain-comments.pdf
     April 16, 2020 - At the present state of medical knowledge, AHRQ is at substantial risk of comprising its professional … There was substantial variability across studies regarding how (or if) use of analgesics in addition … Thank you for your excellent and substantial work on these reports, and we look forward to the publication

206. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/case-management_research-protocol.pdf
     June 06, 2011 - Evidence-based Practice Center Systematic Review Protocol Source: www.effectivehealthcare.ahrq.gov Published Online: June 06, 2011 1 Evidence-based Practice Center Comparative Effectiveness Review Protocol Project Title: Comparative Effectiveness of Case Management for Adults With Medical Illness an…

207. head-neck-cancer-update-140204 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_research-protocol.pdf
     February 04, 2014 - Patient characteristics, which may include substantial co-morbidities and poor performance status, must … We collected a substantial body of evidence from single-arm Source: www.effectivehealthcare.ahrq.gov … Undetected Reporting bias is suspected when: • Testing for funnel plot asymmetry demonstrates a substantial

208. Dietary Intake of Polyunsaturated Fatty Acids and Plasma Lipid and Cardiovascular Events (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/polyunsaturated-fatty-protocol.pdf
     January 01, 2024 - CV events is critically needed prior to updating the Dietary Reference Intake (DRI) values due to substantial

209. Dietary Saturated Fat Replacement and Plasma Lipid and Cardiovascular Events (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/saturated-fat-replacement-protocol.pdf
     January 01, 2024 - concentrations and subsequent CV events is critically needed prior to updating the DRI values due to substantial

210. Use of Natriuretic Peptide Measurement in the Management of Heart Failure | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/heart-failure-natriuretic-peptide/research-protocol

211. Noninvasive Testing for Coronary Artery Disease | Effective Health Care (EHC) Program
     effectivehealthcare.ahrq.gov/products/coronary-artery-disease-testing/research-protocol

212. Disposition of Comments for Strategies To Prevent Weight Gain Among Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-gain-prevention_disposition-comments.pdf
     March 25, 2013 - Adair et al (Adair LS, Gultiano S, Suchindran C. 20- year trends in Filipino women's weight reflect substantial … Such thresholds may make sense for intensive studies of substantial weight loss among obese individuals … Peer Reviewer 4 Discussion The discussion will need substantial revisions once the definition of … We suggest that there be substantial revision to this report before it is released.

213. Disposition of Comments for CER 171 Noninvasive Testing for Coronary Artery Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/coronary-artery-disease-testing_disposition-comments.pdf
     March 29, 2016 - Team clinicians also confirmed that there may be substantial variability across clinical settings … The review team spent substantial time considering ways to standardize presentation of reported risk … There is substantial variability across ED settings for regions across the United States, and patients … The review team spent substantial time considering ways of standardizing the findings on pre-test risks

214. Rapid Evidence Product_Assisted Home Dialysis in the United States: New Interest in an Old Idea (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/home-dialysis-ESKD-rapid-research.pdf
     April 01, 2025 - clinicians and investigators in the United States had recognized that a lack of home support was a substantial

215. labor-dystocia-protocol-amended-160728 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-dystocia_research-protocol.pdf
     July 28, 2016 - This in turn could have substantial impact on the precision of effect estimates, as well as on estimates

216. Crosscutting-Horizon-Scan-High-Impact-1412 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1412.pdf
     December 01, 2014 - preference for propofol sedation coupled with the high cost of anesthesiologist-delivered propofol is a substantial … Multiple commenters cited the substantial training requirements in airway management and Sedasys system … Construction or remodeling, staff training, and new equipment require substantial investment absorbed

217. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1506.pdf
     June 01, 2015 - experts thought that the ReShape device would not substantially alter health care disparities or have a substantial

218. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/dietary-supplements_research-protocol.pdf
     December 15, 2010 - 2011 Page 2 of 26 disease, concomitant use of dietary supplements and prescription drugs is substantial … population, the risk for drug-supplement interactions among patients with cardiovascular disease is substantial

219. Rheumatoid-Arthritis-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
     March 01, 2013 - A2 Substantial harm: A pivotal trial or systematic review (or guidelines) whose results called into … conclusion, then we classified the CER conclusion as possibly out of date. 3 • If we found substantial

220. Rheumatoid-Arthritis-Medicine Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_surveillance.pdf
     March 01, 2013 - A2 Substantial harm: A pivotal trial or systematic review (or guidelines) whose results called into … conclusion, then we classified the CER conclusion as possibly out of date. 3 • If we found substantial