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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/atrial-fibrillation_research-protocol.pdf
    May 22, 2012 - Prevalence of atrial fibrillation in elderly subjects (the Cardiovascular Health Study). … Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. … The Framingham Study. Stroke 1996;27(10):1760-4. PMID: 8841325. 13. … (Catheter Ablation For The Cure Of Atrial Fibrillation Study). … Catheter ablation versus antiarrhythmic drugs for atrial fibrillation: the A4 study.
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_research-protocol.pdf
    February 04, 2014 - The standard variables for subgroup/sensitivity analyses are study size, study quality, and treatment … Score as one of three levels, separately by type of study design: • Low level of study limitations … • Medium level of study limitations • High level of study limitations Directness Required Directness … Score as one of three levels: • Consistent • Inconsistent • Unknown (e.g., single study) Single-study … It includes: • Study publication bias (i.e., nonreporting of the full study) • Selective outcome
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin-future_research.pdf
    August 01, 2014 - Study design considerations Study Design Considerations Randomized Controlled Trial Controlled Before-After … The study group receives the PCT-guided antibiotic treatment strategy part way into the study, and … Study design considerations (continued) Study Design Considerations Randomized Controlled Trial Controlled … The study group receives the PCT-guided antibiotic treatment strategy part way into the study, and … Study design considerations (continued) Study Design Considerations Randomized Controlled Trial Controlled
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/continuous-outcomes-quantitative-synthesis_methods.pdf
    March 01, 2011 - If any of these are missing, the study will be omitted from the meta-analysis. … For example, for the Nelson study, CV=46.2/51.5 = 0.897. … Missing Individuals and Missing Study-Level Characteristics Individuals missing from a study due to … One study had a sample size of 50 with a SD of 6.07 for the mean difference, and the other study had … For example, if in one study a high score indicates depression and in another study a low score indicates
  5. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_executive.pdf
    April 01, 2011 - We accepted any study designs except individual case reports. … Other studies identified potential correlates that warrant further study. … Efficacy of neurofeedback for children in the autistic spectrum: a pilot study. … A pharmacogenetic study of escitalopram in autism spectrum disorders. … Donepezil hydrochloride: A double-blind study in autistic children.
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-195-disposition-comments-uterine-fibroids.pdf
    December 14, 2017 - TEP Reviewer #2 Executive Summary This study is not conclusive. … Study characteristics are poorly defined-large number of studies and inter-study variability may be … TEP Reviewer #2 Results This study is much higher quality than Mara study, also rated as Fair!. … Hence we considered this trial to be a ‘fair’ quality study. … is even further weakened from this already weak study.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/meditation_research-protocol.pdf
    October 17, 2012 - Harms (any noted by the study such as exacerbation of psychosis) Type of study Randomized controlled … For all articles, reviewers will extract information on general study characteristics (e.g., study design … , study period, and follow-up), study participants (e.g., age, gender, race, comorbidities,), eligibility … • Did the strategy for recruiting participants into the study differ across study groups? … single study on the pooled estimate.
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
    June 23, 2014 - Study inclusion criteria Category Criteria for Inclusion Study Enrollment Studies that enroll adults … One investigator will extract relevant study, population demographic, and outcomes data. … We will summarize included study characteristics and outcomes in evidence tables. … Is the study design prospective, retrospective, or mixed? … Are reports of the study free of suggestion of selective outcome reporting?
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/erythropoiesis-stimulating-agents-utilization_research.pdf
    February 01, 2011 - From July 2006 to September 2009 (hereafter referred to as the study period), there was a slight rise … During the study period, the number of beneficiaries without KD (i.e., non-KD beneficiaries) remained … The use of ESAs among beneficiaries on dialysis remained constant over the study period at around 90 … The use of ESAs among beneficiaries with cancer and dialysis remained constant over the study period … The study period, over which ESA use was examined, included July 2006 to September 2009.
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-hospitalizations_research.pdf
    October 01, 2008 - In this study, we determined the positive predictive value (PPV) of computerized case definitions for … This study was approved by the Vanderbilt Institutional Review Board and by the Bureau of TennCare. … We restricted our study to hospitalization records, because outpatient records were not available for … In our study, it was not possible to estimate the sensitivity or the specificity of our definitions. … The burden of community-acquired pneumonia in seniors: results of a population-based study.
  11. S143 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s143.pdf
    October 01, 2007 - (Fig. 1 is a schematic representation of the study.) … Study schematic. … Scandinavian Simvastatin Survival Study Group. … The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group. … Heart Protection Study Collaborative Group.
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_executive.pdf
    June 01, 2013 - Criteria Study design • Controlled studies (randomized trials, cohort studies, case- control studies … ), pooled patient-level meta-analyses, or systematic reviews and study-level meta-analysesb • Study … reports an ovarian cancer outcome of interest and was published on or after Jan. 1,1990d – Study … We stratified analyses by study type (i.e., case-control, cohort, pooled analyses). … We excluded study datasets that reported fewer than three duration categories; reported odds ratios
  13. S23 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s23.pdf
    October 01, 2007 - In the review we found that every second published study does not discuss frequency data and 1 in 3 studies … The study was published in the New England Journal of Medicine (NEJM). … Yale Study Parks FDA Review of Cold Drugs. The Yale Herald News Online 2000. … The Women’s Health Initiative Study Group. … Design of the Women’s Health Initiative clinical trial and observational study.
  14. effectivehealthcare.ahrq.gov/sites/default/files/worker-health_executive.pdf
    April 01, 2016 - We recorded characteristics of study populations, interventions, comparators, settings, study designs … Two independent reviewers assessed the risk of bias for each study. … Work Settings and Populations No study enrolled workers from States in the Southwest; only one study … Process evaluation results from the Healthy Directions-Small Business study. … The COMPASS pilot study: a Total Worker Health™ intervention for home care workers.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cystic-fibrosis-hgh_research-protocol.pdf
    August 22, 2008 - funding, study design characteristics and methodological quality criteria, study population [including … study inclusion and exclusion criteria, run-in period, study withdrawals, dose of rhGH utilized, length … Each study will be assessed for the following individual criteria: comparable study groups at baseline … (follow up adj (study or studies)).tw. 8. … (follow up adj (study or studies)).tw. 8.
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-nitrous-oxide_research-protocol.pdf
    August 24, 2011 - Monitor Study Reviews. … These spreadsheets will allow each author to count key data points, such as study location, study type … , and number of study participants. … Assessment of Methodological Quality of Individual Studies Assess Study Quality. … In the absence of meta- analysis, each study must stand alone.
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_disposition-comments.pdf
    February 25, 2014 - We stand by our assessment of this study as reported. … The study data did contribute to Key Question 5. … as “Good” and a rating of “Fair” for the Oncken, 2008 study. … We have reassessed the risk of bias for this study. … or multicomponent study.
  18. effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence.ppt
    January 01, 2010 - OS = observational study; PICOTS = population, intervention, comparator, outcome, timing, and setting … Risk of bias speaks to the internal validity of a study. … Refocus the study question on gaps in trial evidence. … without detailed review of each study. … question, study design, and the treatments under review.
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence.ppt
    January 01, 2010 - OS = observational study; PICOTS = population, intervention, comparator, outcome, timing, and setting … Risk of bias speaks to the internal validity of a study. … Refocus the study question on gaps in trial evidence. … without detailed review of each study. … question, study design, and the treatments under review.
  20. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
    January 01, 2007 - In the adalimumab study, 25 percent of patients achieved remission in each treatment group. … One prospective cohort study enrolled a population who failed initial RA treatment. … Only one study used sulfasalazine as a synthetic DMARD in combination with a biologic DMARD. … To date, this study is the longest comparative assessment of two biologic treatments for RA. … Results from a six-year observational study in southern Sweden.

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