-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/atrial-fibrillation_research-protocol.pdf
May 22, 2012 - Prevalence of atrial fibrillation in elderly
subjects (the Cardiovascular Health Study). … Atrial fibrillation as an independent risk factor for
stroke: the Framingham Study. … The
Framingham Study. Stroke 1996;27(10):1760-4. PMID: 8841325.
13. … (Catheter Ablation For The Cure Of Atrial Fibrillation Study). … Catheter ablation versus antiarrhythmic drugs for
atrial fibrillation: the A4 study.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_research-protocol.pdf
February 04, 2014 - The standard
variables for subgroup/sensitivity analyses are study size, study quality, and
treatment … Score as one of three
levels, separately by
type of study design:
• Low level of
study limitations … • Medium level of
study limitations
• High level of
study limitations
Directness Required Directness … Score as one of three
levels:
• Consistent
• Inconsistent
• Unknown (e.g.,
single study)
Single-study … It includes:
• Study publication bias (i.e.,
nonreporting of the full study)
• Selective outcome
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin-future_research.pdf
August 01, 2014 - Study design considerations
Study Design
Considerations Randomized Controlled Trial Controlled Before-After … The
study group receives the PCT-guided antibiotic
treatment strategy part way into the study, and … Study design considerations (continued)
Study Design
Considerations Randomized Controlled Trial Controlled … The
study group receives the PCT-guided antibiotic
treatment strategy part way into the study, and … Study design considerations (continued)
Study Design
Considerations Randomized Controlled Trial Controlled
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/continuous-outcomes-quantitative-synthesis_methods.pdf
March 01, 2011 - If any of these are missing, the study will be omitted from the meta-analysis. … For example, for the Nelson study, CV=46.2/51.5 = 0.897. … Missing Individuals and Missing Study-Level Characteristics
Individuals missing from a study due to … One study had a sample size of 50
with a SD of 6.07 for the mean difference, and the other study had … For example, if in one study a high score indicates depression and in
another study a low score indicates
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_executive.pdf
April 01, 2011 - We accepted any study designs except individual case
reports. … Other studies identified potential correlates that warrant
further study. … Efficacy of neurofeedback for children in the
autistic spectrum: a pilot study. … A pharmacogenetic study of
escitalopram in autism spectrum disorders. … Donepezil
hydrochloride: A double-blind study in autistic children.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-195-disposition-comments-uterine-fibroids.pdf
December 14, 2017 - TEP Reviewer #2 Executive
Summary
This study is not conclusive. … Study characteristics are poorly
defined-large number of studies and inter-study variability may
be … TEP Reviewer #2 Results This study is much higher quality than Mara study, also rated as
Fair!. … Hence we considered
this trial to be a ‘fair’ quality study. … is even further weakened from this
already weak study.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/meditation_research-protocol.pdf
October 17, 2012 - Harms (any noted by the study such as
exacerbation of psychosis)
Type of study Randomized controlled … For all articles,
reviewers will extract information on general study characteristics (e.g., study design … , study period, and
follow-up), study participants (e.g., age, gender, race, comorbidities,), eligibility … • Did the strategy for recruiting participants into the study differ across study groups? … single study on the pooled estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
June 23, 2014 - Study inclusion criteria
Category Criteria for Inclusion
Study Enrollment Studies that enroll adults … One investigator will extract relevant study, population demographic, and
outcomes data. … We will summarize included study characteristics and outcomes in evidence tables. … Is the study design
prospective,
retrospective, or mixed? … Are reports of the
study free of suggestion
of selective outcome
reporting?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/erythropoiesis-stimulating-agents-utilization_research.pdf
February 01, 2011 - From July
2006 to September 2009 (hereafter
referred to as the study period), there
was a slight rise … During the study period, the number of
beneficiaries without KD (i.e., non-KD
beneficiaries) remained … The use of ESAs among beneficiaries on dialysis
remained constant over the study period at around 90 … The use of ESAs among beneficiaries
with cancer and dialysis remained constant
over the study period … The study period, over which ESA use was examined, included July 2006 to
September 2009.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-hospitalizations_research.pdf
October 01, 2008 - In
this study, we determined the positive predictive value (PPV) of computerized case definitions
for … This study was approved by the Vanderbilt Institutional Review Board and by
the Bureau of TennCare. … We restricted our study to
hospitalization records, because outpatient records were not available for … In our study, it was not possible to estimate the sensitivity or the specificity of our
definitions. … The burden of
community-acquired pneumonia in seniors:
results of a population-based study.
-
effectivehealthcare.ahrq.gov/sites/default/files/s143.pdf
October 01, 2007 - (Fig.
1 is a schematic representation of the study.) … Study schematic. … Scandinavian Simvastatin Survival Study Group. … The Long-Term Intervention with Pravastatin in Ischaemic Disease
(LIPID) Study Group. … Heart Protection Study Collaborative Group.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_executive.pdf
June 01, 2013 - Criteria
Study design • Controlled studies (randomized trials, cohort studies, case-
control studies … ), pooled patient-level meta-analyses, or
systematic reviews and study-level meta-analysesb
• Study … reports an ovarian cancer outcome of interest and
was published on or after Jan. 1,1990d
– Study … We stratified analyses by study
type (i.e., case-control, cohort, pooled analyses). … We excluded study datasets that reported fewer
than three duration categories; reported odds ratios
-
effectivehealthcare.ahrq.gov/sites/default/files/s23.pdf
October 01, 2007 - In the review we found that every second published
study does not discuss frequency data and 1 in 3 studies … The study was published in
the New England Journal of Medicine (NEJM). … Yale Study Parks FDA Review of Cold Drugs. The Yale
Herald News Online 2000. … The Women’s Health Initiative Study Group. … Design of the Women’s
Health Initiative clinical trial and observational study.
-
effectivehealthcare.ahrq.gov/sites/default/files/worker-health_executive.pdf
April 01, 2016 - We recorded characteristics of study populations,
interventions, comparators, settings, study designs … Two independent reviewers assessed the risk of bias
for each study. … Work Settings and Populations
No study enrolled workers from States in the
Southwest; only one study … Process evaluation
results from the Healthy Directions-Small Business study. … The COMPASS pilot study: a
Total Worker Health™ intervention for home care workers.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cystic-fibrosis-hgh_research-protocol.pdf
August 22, 2008 - funding, study design characteristics and methodological quality criteria, study population
[including … study inclusion and exclusion criteria, run-in period, study withdrawals, dose of rhGH
utilized, length … Each study will be assessed for the following individual criteria: comparable study
groups at baseline … (follow up adj (study or studies)).tw.
8. … (follow up adj (study or studies)).tw.
8.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-nitrous-oxide_research-protocol.pdf
August 24, 2011 - Monitor Study Reviews. … These spreadsheets will allow each author to count key data points,
such as study location, study type … , and number of study participants. … Assessment of Methodological Quality of Individual Studies
Assess Study Quality. … In the absence of meta-
analysis, each study must stand alone.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_disposition-comments.pdf
February 25, 2014 - We
stand by our assessment of this study as reported. … The study data did contribute to Key
Question 5. … as “Good” and a rating of “Fair”
for the Oncken, 2008 study. … We have reassessed the risk of bias for this study. … or
multicomponent study.
-
effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence.ppt
January 01, 2010 - OS = observational study; PICOTS = population, intervention, comparator, outcome, timing, and setting … Risk of bias speaks to the internal validity of a study. … Refocus the study question on gaps in trial evidence. … without detailed review of each study. … question, study design, and the treatments under review.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence.ppt
January 01, 2010 - OS = observational study; PICOTS = population, intervention, comparator, outcome, timing, and setting … Risk of bias speaks to the internal validity of a study. … Refocus the study question on gaps in trial evidence. … without detailed review of each study. … question, study design, and the treatments under review.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
January 01, 2007 - In the
adalimumab study, 25 percent of patients achieved
remission in each treatment group. … One prospective cohort study enrolled a population who
failed initial RA treatment. … Only one study used sulfasalazine as
a synthetic DMARD in combination with a biologic
DMARD. … To date, this study is the
longest comparative assessment of two biologic
treatments for RA. … Results from a six-year observational study in
southern Sweden.